Review: taking Zolpidem tartrate and Melatonin together


Summary

Drug interactions are reported among people who take Zolpidem tartrate and Melatonin together. This review analyzes the effectiveness and drug interactions between Zolpidem tartrate and Melatonin. It is created by eHealthMe based on reports of 685 people who take the same drugs from FDA and social media, and is updated regularly.

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Zolpidem Tartrate

Zolpidem tartrate has active ingredients of zolpidem tartrate. It is often used in insomnia. (latest outcomes from Zolpidem tartrate 15,812 users)

Melatonin

Melatonin has active ingredients of melatonin. It is often used in insomnia. (latest outcomes from Melatonin 8,403 users)

On Sep, 19, 2016

685 people who take Zolpidem Tartrate, Melatonin are studied.


Number of reports submitted per year:

Zolpidem tartrate and Melatonin drug interactions.

Drug effectiveness over time:

Zolpidem Tartrate:
  • < 1 month: 50.0% - (2 of 4 people)
  • 1 - 6 months: 40.0% - (2 of 5 people)
  • 6 - 12 months: 50.0% - (1 of 2 people)
  • 1 - 2 years: 28.0% - (2 of 7 people)
  • 2 - 5 years: 62.0% - (5 of 8 people)
  • 5 - 10 years: 71.0% - (5 of 7 people)
  • 10+ years: 100.0% - (4 of 4 people)
  • not specified: 0.0% - (0 of 0 people)
Melatonin:
  • < 1 month: 0.0% - (0 of 3 people)
  • 1 - 6 months: 12.0% - (1 of 8 people)
  • 6 - 12 months: 37.0% - (3 of 8 people)
  • 1 - 2 years: 0.0% - (0 of 3 people)
  • 2 - 5 years: 0.0% - (0 of 6 people)
  • 5 - 10 years: 100.0% - (1 of 1 people)
  • 10+ years: 50.0% - (3 of 6 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Zolpidem Tartrate:
  • female: 61.0% - (16 of 26 people)
  • male: 45.0% - (5 of 11 people)
Melatonin:
  • female: 26.0% - (7 of 26 people)
  • male: 11.0% - (1 of 9 people)

Drug effectiveness by age:

Zolpidem Tartrate:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (1 of 1 people)
  • 20-29: 57.0% - (4 of 7 people)
  • 30-39: 50.0% - (2 of 4 people)
  • 40-49: 62.0% - (5 of 8 people)
  • 50-59: 66.0% - (6 of 9 people)
  • 60+: 37.0% - (3 of 8 people)
Melatonin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (1 of 1 people)
  • 20-29: 14.0% - (1 of 7 people)
  • 30-39: 25.0% - (1 of 4 people)
  • 40-49: 25.0% - (2 of 8 people)
  • 50-59: 22.0% - (2 of 9 people)
  • 60+: 16.0% - (1 of 6 people)

Most common drug interactions over time *:

< 1 month:
  • urinary retention
  • neutropenic sepsis
  • oedema peripheral
  • pulmonary embolism
  • serotonin syndrome
  • back pain
  • cough
  • deep vein thrombosis
  • dyspnoea
  • pain in extremity
1 - 6 months:
  • fatigue
  • tremor
  • depression
  • lymphadenopathy
  • pain
  • androgens abnormal
  • asthenia
  • back pain
  • bone disorder
  • bone pain
6 - 12 months:
  • liver function test abnormal
  • alanine aminotransferase increased
  • anti-hbc igm antibody positive
  • aspartate aminotransferase increased
  • diaphragm muscle weakness
  • diarrhea
  • frequent headaches
  • insomnia
  • knee pain
  • nausea
1 - 2 years:
  • drug-induced liver injury
  • diaphragm muscle weakness
  • fall
  • fatigue
  • frequent headaches
  • neck stiffness
  • shoulder blade pain
  • alanine aminotransferase increased
  • amnesia
  • arthralgia
2 - 5 years:
  • fall
  • patella fracture
  • anorgasmia
  • delayed ejaculation
  • short-term memory loss
  • urethral pain
  • anxiety
  • bone and joint pain
  • bone loss
  • drug ineffective
5 - 10 years:
  • bloating
  • weight gain
  • hearing loss
  • anxiety and stress
  • tongue irritation
  • vision blurred
  • vision problems
10+ years:
  • benign intracranial hypertension
  • bipolar ii disorder
  • depression
  • frequent headaches
  • insomnia
  • polycystic ovaries
  • postnasal drip
  • short-term memory loss
  • suicidal ideation
  • amnesia
not specified:
  • fatigue
  • insomnia
  • pain
  • headache
  • nausea
  • anxiety
  • dyspnoea
  • drug ineffective
  • constipation
  • depression

Most common drug interactions by gender *:

female:
  • insomnia
  • pain
  • headache
  • nausea
  • fatigue
  • drug ineffective
  • dyspnoea
  • pain in extremity
  • anxiety
  • oedema peripheral
male:
  • fatigue
  • headache
  • nausea
  • insomnia
  • pain
  • pyrexia
  • anxiety
  • dizziness
  • malaise
  • rash

Most common drug interactions by age *:

2-9:
  • anaemia
  • ascites
  • clostridium difficile colitis
  • delirium
  • depressed level of consciousness
  • hypernatraemia
  • hypertension
  • hyponatraemia
  • hypotension
  • hypoxia
10-19:
  • anxiety
  • weight increased
  • abnormal dreams
  • insomnia
  • sleep terror
  • headache
  • fatigue
  • mental impairment
  • pain
  • paradoxical drug reaction
20-29:
  • headache
  • dizziness
  • hallucination, auditory
  • pain
  • deep vein thrombosis
  • amnesia
  • asthenia
  • dyspnoea
  • insomnia
  • musculoskeletal pain
30-39:
  • dizziness
  • headache
  • fall
  • nausea
  • pain
  • arthralgia
  • chest pain
  • drug ineffective
  • fatigue
  • feeling abnormal
40-49:
  • nausea
  • fatigue
  • pain
  • back pain
  • constipation
  • headache
  • anxiety
  • hypoaesthesia
  • depression
  • diarrhoea
50-59:
  • nausea
  • headache
  • insomnia
  • fatigue
  • drug ineffective
  • depression
  • pain
  • rash
  • fall
  • abdominal pain
60+:
  • fatigue
  • insomnia
  • pain
  • headache
  • malaise
  • diarrhoea
  • dizziness
  • pyrexia
  • drug ineffective
  • nausea

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Zolpidem tartrate (zolpidem tartrate) is often used to treat insomnia. Melatonin (melatonin) is often used to treat insomnia. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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