Drug interactions are reported among people who take Zonegran and Vyvanse together. This review analyzes the effectiveness and drug interactions between Zonegran and Vyvanse. It is created by eHealthMe based on reports of 8 people who take the same drugs from FDA and social media, and is updated regularly.
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Zonegran has active ingredients of zonisamide. It is often used in epilepsy. (latest outcomes from Zonegran 2,892 users)
Vyvanse has active ingredients of lisdexamfetamine dimesylate. It is often used in attention deficit hyperactivity disorder. (latest outcomes from Vyvanse 7,909 users)
On Jul, 24, 2016
8 people who take Zonegran, Vyvanse are studied.
* Approximation only. Some reports may have incomplete information.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
I have been taking Zonegran for migraines for 3 months with minimal side effects. I started at 100mg 1x a day for the first month. The second month I increased to 100mg 2x a month. Yesterday my neurologist increased my dose to 200mg 2x a day. On the same day I started baclofen 10mg - 4x a day, which was prescribed by my pain management doctor. I was very confused & weak upon starting the baclofen. I immediately slept a lot, but my sleep was more like unconciousness. I took both meds (my 4th dose of baclofan) at 11pm & very shortly passed out. I woke up at 4:45am unable to breathe & choking. I had mucus blocking my esophagus & clear mucus all over my face. I was wheezing. I managed to cough out the mucus, but it was very difficult & it hurt my esophagus, lungs, & stomach to do it. After I coughed it out & spit it on my bed & the floor I vomited on myself. I also realized I had voided my entire bladder on myself at some point while this was happening. I realized that I had not been breathing much or at all for a while when I was asleep & my saliva had accumulated in my esophagus & I could I have died in my sleep. I was terrified! I called 911 & went to the hospital via ambulance. They gave me a shot of steroids & a breathing treatment. They took an xray of my chest to rule out pneumonia & said that I did not have it. I told them all of the medication I was on, including Zonegran & baclofan, but they did not seem concerned. They discharged me after 4 hours with a prescription for 40mg of prednisone for 3 days & told me to follow up with my doctor. They told me they saw no reason for me to stop taking the baclofen, as they did not think it caused the problem. I think that they were WRONG, but I didn't know what to say or do. I called my doctor when I got home. Today is a Friday & her nurse said that she could not see me until Monday. She also said that she saw no reason to discontinue the baclofen, unless I merely wanted to. I am scared that this happened. I am anxious that no one seems to see the connection that I do. I am desperate for relief for the pain in my spine, so I will call my pain management doctor's office on Monday & tell them what happened & why I think it did, as well as go & see my regular doctor. But I am scared to sleep tonight. It was such a relief to see here that this side effect with these two drugs is a known one. I hope to get more knowledge here in this forum.
On eHealthMe, Zonegran (zonisamide) is often used to treat epilepsy. Vyvanse (lisdexamfetamine dimesylate) is often used to treat attention deficit hyperactivity disorder. Find out below the conditions the drugs are used for and how effective they are.
NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.
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