Review: taking Zyprexa and Seroquel together


Summary

Drug interactions are reported among people who take Zyprexa and Seroquel together. This review analyzes the effectiveness and drug interactions between Zyprexa and Seroquel. It is created by eHealthMe based on reports of 8,285 people who take the same drugs from FDA and social media, and is updated regularly.

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Zyprexa

Zyprexa has active ingredients of olanzapine. It is often used in schizophrenia. (latest outcomes from Zyprexa 45,357 users)

Seroquel

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. (latest outcomes from Seroquel 81,424 users)

On Aug, 25, 2016

8,285 people who take Zyprexa, Seroquel are studied.


Number of reports submitted per year:

Zyprexa and Seroquel drug interactions.

Drug effectiveness over time:

Zyprexa:
  • < 1 month: 9.0% - (1 of 11 people)
  • 1 - 6 months: 40.0% - (2 of 5 people)
  • 6 - 12 months: 66.0% - (2 of 3 people)
  • 1 - 2 years: 20.0% - (1 of 5 people)
  • 2 - 5 years: 16.0% - (1 of 6 people)
  • 5 - 10 years: 100.0% - (2 of 2 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 100.0% - (2 of 2 people)
Seroquel:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 10.0% - (1 of 10 people)
  • 6 - 12 months: 0.0% - (0 of 2 people)
  • 1 - 2 years: 62.0% - (5 of 8 people)
  • 2 - 5 years: 16.0% - (1 of 6 people)
  • 5 - 10 years: 0.0% - (0 of 2 people)
  • 10+ years: 0.0% - (0 of 2 people)
  • not specified: 100.0% - (1 of 1 people)

Drug effectiveness by gender:

Zyprexa:
  • female: 53.0% - (8 of 15 people)
  • male: 20.0% - (4 of 20 people)
Seroquel:
  • female: 40.0% - (6 of 15 people)
  • male: 11.0% - (2 of 18 people)

Drug effectiveness by age:

Zyprexa:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 1 people)
  • 10-19: 0.0% - (0 of 3 people)
  • 20-29: 85.0% - (6 of 7 people)
  • 30-39: 14.0% - (1 of 7 people)
  • 40-49: 0.0% - (0 of 4 people)
  • 50-59: 44.0% - (4 of 9 people)
  • 60+: 25.0% - (1 of 4 people)
Seroquel:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 1 people)
  • 10-19: 0.0% - (0 of 3 people)
  • 20-29: 71.0% - (5 of 7 people)
  • 30-39: 33.0% - (2 of 6 people)
  • 40-49: 0.0% - (0 of 4 people)
  • 50-59: 11.0% - (1 of 9 people)
  • 60+: 0.0% - (0 of 3 people)

Most common drug interactions over time *:

< 1 month:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • psychotic disorder
  • blood cholesterol increased
  • hyperglycaemia
  • weight increased
  • blood triglycerides increased
  • pancreatitis
  • suicidal ideation
  • hyperlipidaemia
1 - 6 months:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • weight increased
  • blood cholesterol increased
  • pancreatitis
  • hyperglycaemia
  • chest pain
  • hyperlipidaemia
  • neuropathy peripheral
  • obesity
6 - 12 months:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • obesity
  • weight increased
  • blood cholesterol increased
  • pancreatitis
  • diabetic ketoacidosis
  • neuropathy peripheral
  • hyperglycaemia
  • diabetes mellitus inadequate control
1 - 2 years:
  • diabetes mellitus
  • type 2 diabetes mellitus
  • blood cholesterol increased
  • pancreatitis
  • obesity
  • hyperglycaemia
  • diabetes mellitus inadequate control
  • hyperlipidaemia
  • diabetic ketoacidosis
  • blood triglycerides increased
2 - 5 years:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • blood cholesterol increased
  • obesity
  • pancreatitis
  • hyperglycaemia
  • diabetes mellitus inadequate control
  • weight increased
  • neuropathy peripheral
  • diabetic neuropathy
5 - 10 years:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • blood cholesterol increased
  • obesity
  • pancreatitis
  • hyperglycaemia
  • neuropathy peripheral
  • blood triglycerides increased
  • hyperlipidaemia
  • diabetes mellitus inadequate control
10+ years:
  • type 2 diabetes mellitus
  • pancreatitis
  • diabetes mellitus
  • blood cholesterol increased
  • obesity
  • renal failure chronic
  • hyperlipidaemia
  • diabetic ketoacidosis
  • malaise
  • urinary tract infection
not specified:
  • diabetes mellitus
  • type 2 diabetes mellitus
  • weight increased
  • pancreatitis
  • blood cholesterol increased
  • hyperglycaemia
  • diabetes mellitus inadequate control
  • obesity
  • diabetic neuropathy
  • diabetic ketoacidosis

Most common drug interactions by gender *:

female:
  • diabetes mellitus
  • type 2 diabetes mellitus
  • blood cholesterol increased
  • pancreatitis
  • weight increased
  • obesity
  • hyperglycaemia
  • diabetes mellitus inadequate control
  • hyperlipidaemia
  • diabetic neuropathy
male:
  • diabetes mellitus
  • type 2 diabetes mellitus
  • weight increased
  • pancreatitis
  • blood cholesterol increased
  • hyperglycaemia
  • obesity
  • diabetes mellitus inadequate control
  • diabetic ketoacidosis
  • neuropathy peripheral

Most common drug interactions by age *:

0-1:
  • diabetes mellitus
  • pancreatitis
  • type 2 diabetes mellitus
  • death
  • diabetic ketoacidosis
  • diabetic coma
  • cleft palate
  • high arched palate
  • feeding disorder neonatal
  • foetal exposure during pregnancy
2-9:
  • weight increased
  • hyperglycaemia
  • dizziness
  • aggression
  • obesity
  • dyspnoea
  • dysstasia
  • eye movement disorder
  • gastric dilatation
  • pancreatitis
10-19:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • weight increased
  • suicidal ideation
  • diabetic ketoacidosis
  • anxiety
  • abnormal behaviour
  • obesity
  • type 1 diabetes mellitus
  • agitation
20-29:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • blood cholesterol increased
  • weight increased
  • hyperglycaemia
  • suicidal ideation
  • pancreatitis
  • psychotic disorder
  • diabetes mellitus inadequate control
  • diabetic ketoacidosis
30-39:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • blood cholesterol increased
  • obesity
  • diabetes mellitus inadequate control
  • pancreatitis
  • hyperglycaemia
  • weight increased
  • diabetic neuropathy
  • hyperlipidaemia
40-49:
  • diabetes mellitus
  • type 2 diabetes mellitus
  • blood cholesterol increased
  • pancreatitis
  • diabetes mellitus inadequate control
  • obesity
  • neuropathy peripheral
  • weight increased
  • hyperglycaemia
  • blood triglycerides increased
50-59:
  • diabetes mellitus
  • type 2 diabetes mellitus
  • pancreatitis
  • blood cholesterol increased
  • weight increased
  • neuropathy peripheral
  • diabetic neuropathy
  • hyperglycaemia
  • diabetes mellitus inadequate control
  • obesity
60+:
  • diabetes mellitus
  • type 2 diabetes mellitus
  • hyperglycaemia
  • weight increased
  • tremor
  • death
  • diabetic neuropathy
  • confusional state
  • hypertension
  • anxiety

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Zyprexa (olanzapine) is often used to treat schizophrenia. Seroquel (quetiapine fumarate) is often used to treat bipolar disorder. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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