Review: taking Zyrtec and Acetaminophen together


Summary

Drug interactions are reported among people who take Zyrtec and Acetaminophen together. This review analyzes the effectiveness and drug interactions between Zyrtec and Acetaminophen. It is created by eHealthMe based on reports of 3,024 people who take the same drugs from FDA and social media, and is updated regularly.

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Zyrtec

Zyrtec has active ingredients of cetirizine hydrochloride. It is often used in hypersensitivity. (latest outcomes from Zyrtec 33,169 users)

Acetaminophen

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. (latest outcomes from Acetaminophen 72,922 users)

On Aug, 21, 2016

3,024 people who take Zyrtec, Acetaminophen are studied.


Number of reports submitted per year:

Zyrtec and Acetaminophen drug interactions.

Drug effectiveness over time:

Zyrtec:
  • < 1 month: 18.0% - (2 of 11 people)
  • 1 - 6 months: 42.0% - (6 of 14 people)
  • 6 - 12 months: 25.0% - (1 of 4 people)
  • 1 - 2 years: 33.0% - (2 of 6 people)
  • 2 - 5 years: 27.0% - (3 of 11 people)
  • 5 - 10 years: 22.0% - (2 of 9 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 0.0% - (0 of 1 people)
Acetaminophen:
  • < 1 month: 41.0% - (5 of 12 people)
  • 1 - 6 months: 33.0% - (1 of 3 people)
  • 6 - 12 months: 0.0% - (0 of 3 people)
  • 1 - 2 years: 28.0% - (2 of 7 people)
  • 2 - 5 years: 50.0% - (3 of 6 people)
  • 5 - 10 years: 50.0% - (4 of 8 people)
  • 10+ years: 54.0% - (6 of 11 people)
  • not specified: 0.0% - (0 of 2 people)

Drug effectiveness by gender:

Zyrtec:
  • female: 25.0% - (9 of 36 people)
  • male: 38.0% - (8 of 21 people)
Acetaminophen:
  • female: 34.0% - (12 of 35 people)
  • male: 52.0% - (9 of 17 people)

Drug effectiveness by age:

Zyrtec:
  • 0-1: 0.0% - (0 of 1 people)
  • 2-9: 20.0% - (1 of 5 people)
  • 10-19: 14.0% - (1 of 7 people)
  • 20-29: 85.0% - (6 of 7 people)
  • 30-39: 45.0% - (5 of 11 people)
  • 40-49: 0.0% - (0 of 8 people)
  • 50-59: 37.0% - (3 of 8 people)
  • 60+: 10.0% - (1 of 10 people)
Acetaminophen:
  • 0-1: 100.0% - (1 of 1 people)
  • 2-9: 25.0% - (1 of 4 people)
  • 10-19: 42.0% - (3 of 7 people)
  • 20-29: 50.0% - (3 of 6 people)
  • 30-39: 63.0% - (7 of 11 people)
  • 40-49: 66.0% - (4 of 6 people)
  • 50-59: 12.0% - (1 of 8 people)
  • 60+: 11.0% - (1 of 9 people)

Most common drug interactions over time *:

< 1 month:
  • pyrexia
  • infusion related reaction
  • hepatic enzyme increased
  • rash
  • vomiting
  • malaise
  • restlessness
  • abdominal discomfort
  • fistula
  • dyspnoea
1 - 6 months:
  • thinking abnormal
  • erythema
  • violence-related symptom
  • chest pain
  • cough
  • fatigue
  • lip swelling
  • oral discomfort
  • photosensitivity reaction
  • pruritus
6 - 12 months:
  • thrombocytopenia
  • aortic valve incompetence
  • atrial septal defect
  • cyanosis neonatal
  • meningitis aseptic
  • meningitis enteroviral
  • meningitis neonatal
  • pulmonary valve stenosis
  • respiratory distress
  • pneumonia bacterial
1 - 2 years:
  • itching scar
  • hepatitis c
  • lipodystrophy
  • muscle cramps
  • syncope
  • back pain
  • cough
  • faeces pale
  • fatigue
  • night sweats
2 - 5 years:
  • anaemia
  • difficulty passing stool
  • leg cramps
  • lower respiratory tract infection
  • short-term memory loss
  • watery eyes
  • lipodystrophy
  • muscle cramps
  • syncope
  • fatigue
5 - 10 years:
  • difficulty passing stool
  • insomnia
  • leg cramps
  • short-term memory loss
  • watery eyes
  • abnormal dreams
  • drowsiness
  • fatigue
  • restlessness
  • tremor
10+ years:
  • backache
  • chronic pancreatitis
  • epilepsy
  • fatigue
  • generalised anxiety disorder
  • major depression
  • migraine without aura
  • pain - neck
  • tension headaches
  • trigeminal neuralgia
not specified:
  • nausea
  • pain
  • pyrexia
  • fatigue
  • dyspnoea
  • headache
  • vomiting
  • anxiety
  • dizziness
  • arthralgia

Most common drug interactions by gender *:

female:
  • nausea
  • pain
  • fatigue
  • vomiting
  • headache
  • pyrexia
  • anxiety
  • dyspnoea
  • dizziness
  • diarrhoea
male:
  • pyrexia
  • dyspnoea
  • pain
  • insomnia
  • headache
  • nausea
  • fatigue
  • dizziness
  • arthralgia
  • diarrhoea

Most common drug interactions by age *:

0-1:
  • pyrexia
  • chills
  • insomnia
  • eating disorder
  • wheezing
  • dyspnoea
  • malaise
  • adverse event
  • thrombocytopenia
  • vomiting
2-9:
  • wheezing
  • dyspnoea
  • pneumonia
  • adverse event
  • pyrexia
  • lethargy
  • diarrhoea
  • vomiting
  • abdominal pain upper
  • lymphadenopathy
10-19:
  • pyrexia
  • vomiting
  • pain
  • headache
  • dyspnoea
  • suicide attempt
  • abdominal pain
  • nausea
  • suicidal ideation
  • clostridial infection
20-29:
  • fatigue
  • pyrexia
  • pain
  • vomiting
  • nausea
  • upper respiratory tract infection
  • dizziness
  • asthenia
  • headache
  • hodgkin's disease
30-39:
  • fatigue
  • anaemia
  • blood pressure increased
  • sinusitis
  • arthralgia
  • abdominal pain
  • pruritus
  • pulmonary embolism
  • nausea
  • depression
40-49:
  • headache
  • nausea
  • anxiety
  • fatigue
  • vomiting
  • pain
  • dizziness
  • chest pain
  • injury
  • depression
50-59:
  • nausea
  • pain
  • pyrexia
  • arthralgia
  • headache
  • fall
  • depression
  • anxiety
  • dizziness
  • fatigue
60+:
  • nausea
  • dyspnoea
  • fatigue
  • diarrhoea
  • pain
  • pneumonia
  • asthenia
  • pyrexia
  • dizziness
  • vomiting

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Zyrtec (cetirizine hydrochloride) is often used to treat hypersensitivity. Acetaminophen (acetaminophen) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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