Review: taking Zyrtec and Advil together


Summary

Drug interactions are reported among people who take Zyrtec and Advil together. This review analyzes the effectiveness and drug interactions between Zyrtec and Advil. It is created by eHealthMe based on reports of 2,136 people who take the same drugs from FDA and social media, and is updated regularly.

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Zyrtec

Zyrtec has active ingredients of cetirizine hydrochloride. It is often used in hypersensitivity. (latest outcomes from Zyrtec 29,632 users)

Advil

Advil has active ingredients of ibuprofen. It is often used in pain. (latest outcomes from Advil 17,452 users)

On Jul, 27, 2016

2,136 people who take Zyrtec, Advil are studied.


Number of reports submitted per year:

Zyrtec and Advil drug interactions.

Drug effectiveness over time:

Zyrtec:
  • < 1 month: 18.0% - (4 of 22 people)
  • 1 - 6 months: 50.0% - (9 of 18 people)
  • 6 - 12 months: 20.0% - (2 of 10 people)
  • 1 - 2 years: 40.0% - (8 of 20 people)
  • 2 - 5 years: 53.0% - (17 of 32 people)
  • 5 - 10 years: 64.0% - (9 of 14 people)
  • 10+ years: 66.0% - (4 of 6 people)
  • not specified: 100.0% - (1 of 1 people)
Advil:
  • < 1 month: 63.0% - (23 of 36 people)
  • 1 - 6 months: 46.0% - (7 of 15 people)
  • 6 - 12 months: 0.0% - (0 of 7 people)
  • 1 - 2 years: 58.0% - (7 of 12 people)
  • 2 - 5 years: 41.0% - (7 of 17 people)
  • 5 - 10 years: 77.0% - (7 of 9 people)
  • 10+ years: 67.0% - (19 of 28 people)
  • not specified: 20.0% - (1 of 5 people)

Drug effectiveness by gender:

Zyrtec:
  • female: 40.0% - (38 of 93 people)
  • male: 53.0% - (16 of 30 people)
Advil:
  • female: 52.0% - (52 of 99 people)
  • male: 63.0% - (19 of 30 people)

Drug effectiveness by age:

Zyrtec:
  • 0-1: 0.0% - (0 of 1 people)
  • 2-9: 42.0% - (3 of 7 people)
  • 10-19: 40.0% - (4 of 10 people)
  • 20-29: 52.0% - (9 of 17 people)
  • 30-39: 50.0% - (15 of 30 people)
  • 40-49: 46.0% - (12 of 26 people)
  • 50-59: 26.0% - (5 of 19 people)
  • 60+: 46.0% - (6 of 13 people)
Advil:
  • 0-1: 100.0% - (2 of 2 people)
  • 2-9: 75.0% - (6 of 8 people)
  • 10-19: 40.0% - (4 of 10 people)
  • 20-29: 44.0% - (8 of 18 people)
  • 30-39: 65.0% - (19 of 29 people)
  • 40-49: 57.0% - (16 of 28 people)
  • 50-59: 42.0% - (9 of 21 people)
  • 60+: 53.0% - (7 of 13 people)

Most common drug interactions over time *:

< 1 month:
  • sinusitis
  • conjunctivitis
  • croup infectious
  • acute tonsillitis
  • bronchitis
  • gastroenteritis
  • pneumonia
  • reflux oesophagitis
  • rhinitis
  • dyspnoea
1 - 6 months:
  • conjunctivitis
  • acute tonsillitis
  • bronchitis
  • croup infectious
  • gastroenteritis
  • pneumonia
  • reflux oesophagitis
  • rhinitis
  • sinusitis
  • congenital cystic kidney disease
6 - 12 months:
  • muscle spasms
  • anxiety
  • back pain
  • dizziness
  • pain
  • swelling of fingers
  • weight gain
  • abdominal pain
  • biliary dyskinesia
  • bruxism
1 - 2 years:
  • cerebrovascular accident
  • hypertension
  • metabolic acidosis
  • metabolic alkalosis
  • fatigue aggravated
  • headache
  • musculoskeletal stiffness
  • nausea
  • pyrexia
  • vomiting
2 - 5 years:
  • colonic polyp
  • dizziness
  • weight gain
  • back pain
  • muscle spasms
  • swelling of fingers
  • fatigue
  • headache
  • lipodystrophy
  • memory impairment
5 - 10 years:
  • anxiety
  • deep vein thrombosis
  • depression
  • cholecystitis chronic
  • pain
  • injury
  • pulmonary embolism
  • emotional distress
  • general physical health deterioration
  • insomnia
10+ years:
  • cholecystitis chronic
  • pain
  • deep vein thrombosis
  • injury
  • anxiety
  • cholelithiasis
  • depression
  • fatigue
  • gallbladder disorder
  • hair loss
not specified:
  • pain
  • pyrexia
  • nausea
  • anxiety
  • dyspnoea
  • vomiting
  • fatigue
  • arthralgia
  • headache
  • back pain

Most common drug interactions by gender *:

female:
  • pain
  • anxiety
  • nausea
  • dyspnoea
  • headache
  • deep vein thrombosis
  • fatigue
  • pulmonary embolism
  • injury
  • pyrexia
male:
  • pyrexia
  • sinusitis
  • vomiting
  • nausea
  • pain
  • dyspnoea
  • pneumonia
  • insomnia
  • fatigue
  • fall

Most common drug interactions by age *:

0-1:
  • chills
  • insomnia
  • pyrexia
  • eating disorder
  • wheezing
  • dyspnoea
  • malaise
  • adverse event
  • pneumonia
  • erythema multiforme
2-9:
  • pyrexia
  • vomiting
  • erythema multiforme
  • eye swelling
  • ear infection
  • lip swelling
  • rash
  • malaise
  • urticaria
  • dyspnoea
10-19:
  • vomiting
  • pain
  • clostridial infection
  • dyspnoea
  • histiocytosis haematophagic
  • pyrexia
  • pulmonary embolism
  • nausea
  • abdominal pain
  • pleural effusion
20-29:
  • pain
  • pulmonary embolism
  • fatigue
  • anxiety
  • dizziness
  • hodgkin's disease
  • injury
  • night sweats
  • deep vein thrombosis
  • upper respiratory tract infection
30-39:
  • pain
  • deep vein thrombosis
  • anxiety
  • pulmonary embolism
  • cholecystitis chronic
  • injury
  • nausea
  • fatigue
  • gallbladder disorder
  • weight increased
40-49:
  • pain
  • anxiety
  • injury
  • nausea
  • anaemia
  • arthralgia
  • deep vein thrombosis
  • headache
  • back pain
  • osteonecrosis of jaw
50-59:
  • pain
  • arthralgia
  • nausea
  • cerebrovascular accident
  • headache
  • back pain
  • hypoaesthesia
  • dyspnoea
  • diarrhoea
  • anxiety
60+:
  • pain
  • nausea
  • chest pain
  • fatigue
  • pneumonia
  • dyspnoea
  • anxiety
  • asthenia
  • hypotension
  • pleural effusion

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Zyrtec (cetirizine hydrochloride) is often used to treat hypersensitivity. Advil (ibuprofen) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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