A study of drug interactions between Lyrica, Valium, Vicodin, Percocet, Flexeril, Dilaudid, Skelaxin, Amlodipine for a Male patient aged 50
This is a personalized study of Lyrica, Valium, Vicodin, Percocet, Flexeril, Dilaudid, Skelaxin, Amlodipine drug interactions for a 50 year old male patient. The study is created by eHealthMe based on 3 reports from FDA.
Do you have chronic disease and take multiple drugs? eHealthMe can monitor your drugs and notify you when there are serious drug reactions detected. Our original studies have been used on premier medical publications. The monitor will be personalized to your gender and age. Start now
What are the drugs
Lyrica has active ingredients of pregabalin. It is used in fibromyalgia, pain, neuralgia, peripheral neuropathy, neuropathy peripheral, neuropathic pain.
Valium has active ingredients of diazepam. It is used in stress and anxiety, generalized anxiety disorder, muscle spasms, insomnia, muscle relaxant therapy, sleep disorder.
Vicodin has active ingredients of acetaminophen; hydrocodone bitartrate. It is used in pain, back pain - low, back pain, surgery, pain in limb, arthritis.
Percocet has active ingredients of acetaminophen; oxycodone hydrochloride. It is used in pain, back pain - low, back pain, surgery, fibromyalgia, pain in extremity.
Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is used in muscle spasms, back pain - low, muscle aches, pain, muscle injury, fibromyalgia.
Dilaudid has active ingredients of hydromorphone hydrochloride. It is used in pain, back pain - low, migraine, pain in extremity, post surgical pain, kidney stones.
Skelaxin has active ingredients of metaxalone. It is used in muscle spasms, back pain - low, muscle aches, pain, muscle relaxant therapy, back pain.
Amlodipine has active ingredients of amlodipine besylate. It is used in high blood pressure.
On Apr, 19, 2013: 3 people who reported to have interactions when taking Lyrica, Valium, Vicodin, Percocet, Flexeril, Dilaudid, Skelaxin, Amlodipine are studied
Information of the patient in this study:
Age: 50
Gender: male
Conditions: Sciatica, Hypertension, Pain
Drugs taking:
- Lyrica
- Valium
- Lyrica
- Vicodin
- Percocet
- Flexeril
- Dilaudid
- Skelaxin
- Amlodipine
- Lyrica
Drug interactions have: Oedema Peripheral, Multiple Sclerosis, Joint Swelling, Intervertebral Disc Protrusion, Coma
eHealthMe real world results:
For males aged 50 (±5):
Comparison with this patient's adverse outcomes:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports |
| Oedema Peripheral | 3 (100.00%) |
| Multiple Sclerosis | 2 (66.67%) |
| Joint Swelling | 3 (100.00%) |
| Intervertebral Disc Protrusion | 3 (100.00%) |
| Coma | 3 (100.00%) |
Most common interactions experienced by males aged 50 (±5) in the use of Lyrica, Valium, Vicodin, Percocet, Flexeril, Dilaudid, Skelaxin, Amlodipine:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports | |
| 1 | Coma | 3 |
| 2 | Oedema Peripheral | 3 |
| 3 | Joint Swelling | 3 |
| 4 | Intervertebral Disc Protrusion | 3 |
| 5 | Multiple Sclerosis | 2 |
| 6 | Multiple Sclerosis Relapse | 1 |
Login or sign up (it's free) to view more results. Or personalize this study
Most common interactions experienced by males aged 50 (±5) in long term use of Lyrica, Valium, Vicodin, Percocet, Flexeril, Dilaudid, Skelaxin, Amlodipine:
(click on each outcome to view in-depth analysis, incl. how people recovered)| None. |
For people in general (regardless of gender or age):
Comparison with this patient's adverse outcomes:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports |
| Oedema Peripheral | 3 (100.00%) |
| Multiple Sclerosis | 2 (66.67%) |
| Joint Swelling | 3 (100.00%) |
| Intervertebral Disc Protrusion | 3 (100.00%) |
| Coma | 3 (100.00%) |
Most common interactions experienced by people in the use of Lyrica, Valium, Vicodin, Percocet, Flexeril, Dilaudid, Skelaxin, Amlodipine:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports | |
| 1 | Coma | 3 |
| 2 | Oedema Peripheral | 3 |
| 3 | Joint Swelling | 3 |
| 4 | Intervertebral Disc Protrusion | 3 |
| 5 | Multiple Sclerosis | 2 |
| 6 | Multiple Sclerosis Relapse | 1 |
Login or sign up (it's free) to view more results. Or personalize this study
Most common interactions experienced by people in long term use of Lyrica, Valium, Vicodin, Percocet, Flexeril, Dilaudid, Skelaxin, Amlodipine:
(click on each outcome to view in-depth analysis, incl. how people recovered)| None. |
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Next: study your drugs
You can also:
- get notified of updates of this study
- post a comment or see what 123 people said
- let eHealthMe monitor your drugs
- get our mobile app: never miss a symptom, compare it with patients like me in real time, and discuss it with doctors later
- still have questions? Check any related studies below
Drug effectiveness in real world:
- Amlodipine for Hypertension reported by 41 people (updated 1 day ago)
- Lyrica for Pain reported by 162 people (updated 5 days ago)
- Lyrica for Sciatica reported by 12 people (updated 3 months ago)
Alternative drugs:
- Hypertension (228 drugs) (updated 2 hours ago)
- Pain (206 drugs) (updated 1 day ago)
- Sciatica (20 drugs) (updated 4 weeks ago)
Comments from related studies:
From this study (1 week ago):
From this study (2 weeks ago):
From this study (1 month ago):
From this study (2 months ago):
From this study (2 months ago):
peanuts on Mar, 31, 2010:
my friend is suffering from rhumatory arthertis.and is currenty taking cocaine. oxy cotin,prestine, wellbutrim, predisone 10mg what side effects should she expect ?????
jimmy on Apr, 29, 2013:
Susan,
Finally, I'd been reading thru here and finnaly, what doctor in the U.S. still prescribes cocaine? LOL
jimmy on Apr, 29, 2013:
IF you donT see my other comments, Never take Cymbalta or anything containing same ingrediants or speeding thru the same side effects durring their enjoyable living advertizements!
Jmsrocks on Jul, 25, 2012:
Probably death. Cocain and opiates together = speed ball.
Hebe on Jul, 31, 2012:
I have had two close relatives on prednisone, and for both of them it alone can make them feel really speedy. Combined with cocaine and wellbutrin would probably make sleeping very difficult. As the previous commenter mentioned, combining oxys into this is probably a bit dangerous.
Patty O'Neill on Aug, 10, 2012:
The comments about death in combination with cocaine and opiates or any other drug is possible
depending on how much and the situation. Frightening people is not the key here. Basically any drug in combination with another could cause a major health problem as we are all very much not the same makeup. Cheers,
ken on Aug, 17, 2012:
If she continues with this type of treatment, its kinda scary in all reality. Why not see a doctor, that's where the healing may start.
Jackie on Apr, 30, 2013:
I am wondering if you were diagnosed because you had pain and found out you had a neurological message going on.... or just a process of elimination over the pain after you were taking your anti psychotic medication? I've been taking oxycone for my pain my back and neck disc issues um for about a year now, was having joint pain and stiffness all over my body the Dr put me on cymbalta and now three weeks later he put me on wellbutrin and I'm wondering about seratonin syndrome... I'm having muscle twitching also lump on top of my head and vision problems.
iCaNtCaLlIt on Oct, 24, 2012:
Please coke for arthrit.? take your fish oils 2 each meal and take your perscribed pain meds(careful very addicting) stop the coke thats being silly for real. goodluck, lifes a bych and ya die thats why we get high .. p.s ankle 9 surgerys plates screws never walk normal again, fight thru it..i got hurt at work btw 7 ton crushed my leg instead of me....jus always think thingd can be worse, be a gpod person dont let this bring u dwn n b miserable..pul thru keep head up n watch those pain meds..goodluck...email if u wana talk but dont come with negatibity. buhbye
susan on Jan, 3, 2013:
have vit d blood levles ck, and supplenment. vit d is an amazing pain control helper.
nefariouson3 on Nov, 7, 2012:
I too am a chronic pain sufferer, I drove over a explosive in the middle-east. I don't understand what or why this thread was written up like a true medical study, to me it looks more like a recreational train wreck, some listed drugs have reverse reactions and others simply have no medical need what so ever, personally I would seek professional help and attempt to get off the unneeded drugs and concentrate on the true medical issues. At your age 51, you run the risk of many complications and possibility death from the listed drugs, though who am I to judge, life is way too short enjoy it when your still alive.
Th3
Had'em all on Nov, 14, 2012:
Prison and/or death. Comparing taking coke by inhalation and oxycontin orally is NOT the same thing as speed ball. Kindergarten speed ball maybe. Addiction threshold of oxy is 60mg/day. She should try to stay below that.
Get her the hell off Pristine/Ketoconazole unless it is absolutely positively necessary. If necessary, try to get a lower dose. Stuff fries the liver & with all the other crap--BAD idea.
Is there a reason she isn't taking an NSAID? I see prednisone. Would help more than oxy.
kobe77 on Jan, 3, 2013:
Lmao! Lmao! You sound like your high ......enjoy your trip!
knowledgable on Jan, 7, 2013:
Death bed us what they should expect. Mixing cocaine and oxy, are they brainless!!!!
Sydney on Jan, 9, 2013:
Tell your friend to GET OFF WHEAT. The wheat products in this country are GMO which are very bad for us and cause arthritis. Tell your friend to research. Never let the Dr.s try and figure out what's wrong with you. They won't. And they'll kill you trying.
nursing101 on Jan, 28, 2013:
Well, NSAID, you say? Hmmm....I see motrin, naproxen and aspirin on the list....all NSAID's
Billy on Feb, 2, 2013:
It is a wonder that your wife is at all coherent taking that cocktail of medications. I would try to find a new doctor that has a better grasp of toxicology and drug interactions. Cocaine and Oxycotin--can't belief any reputable doctor would prescribe that combination.
High depression low motivation on Feb, 8, 2013:
I take fish oils and centrum vitamins for depression replacing latuda and Lexapro wich was messing with my school I was out of phase sleeping all day and cloudy thinking. Now I just take Adderall and Xanax for agoraphobia and I feel a lot better and Im actually doing homework!! I scored high on my test than on the antidepressants with low scores.
AdoreTu on Mar, 4, 2013:
Well, I just stopped at your post, and who ever is taking all of that stuff needs to take some Milk Thistle to help restore their liver.
Sam on Mar, 11, 2013:
Way back in the late 1960's I heard it called a combination of cocaine and opiate type drugs a speedball. My best guess is your friend is on the way out of this world, unless there is an intervention. In short, death is the end result/side effect of taking such a combination of drugs....
Deo Vindece,
Sam
BCS on Mar, 12, 2013:
Honestly. She can expect to die very young.
Everything from heart, kidney, liver, stomach, brain, lungs, immune system, etc. will began to shut down.
She will most likely become increasingly weak, finding herself in the hospital more often, and eventually die of organ failure. that is unless she dies from an overdoes first.
bcs on Mar, 12, 2013:
Yeah, hybrid wheat is causing all the problems. not the cocaine and oxy, mixed with other prescription drugs.
I agree Hybrid wheat is harmful and best left out of ones diet, but it's not the biggest problem here. (it hybrid not gmo) they haven't released that yet.
Susan on Mar, 12, 2013:
Are you guys really this dumb? She meant to say her friend was taking Codeine not cocaine. I'm not even going to bother asking a question on this website if you're that dumb! LOL
Jenn on Mar, 15, 2013:
I know that I am super sensitive to both codeine and oxy. They actually make me more nauseous and dizzy and i find regular tylenol or ibuprophen to be more effective against pain. I have heard some good things about omega fish oil and gluten free diets. My sister has RA too and when she flares up even pain meds dont help much. She is also gluten intolerant and can feel a marked difference in symptoms when she "slips" and eats gluten-y things. Steroids make your blood pressure high, she takes them when she gets flare ups but tries to ween herself off as the flare up dissipates. She gets weird skin breakouts because steroids also mess with the natural flora of your body. RA sux!!!!
doc moc on Mar, 25, 2013:
have tou tried cocaine? pretty sure its gluten free our previous inquisitor seemed to have some luck with its administration in combination with an assortment of other medications to treat her condition also as far as the flora issue goes i dont think cocaine is an antagonist
doc moc on Mar, 30, 2013:
oh yes BCS i agree hybrid wheat is a very dangerous substance especially when compared to the rather inocuous substances of cocaine and oxycontin! just what are your qualifications to dispense such well researched and supported opinions? You are truly a fool
Stephanie on Apr, 1, 2013:
Yeah I'm pretty sure she ment codeine. i dont visit these sites often anymore becasue my questions never get answered and everything gets way off topic.
really on Apr, 10, 2013:
people like you should visit your local humane society and have yourself spayed or neutered because the human race does not need less intelligent, human-jackass hybrid beings breeding with those of greater intellect. Cocaine was clearly written, not codeine. and please don't post your questions, prefer you be the guinea pig and take risks alerting the people who matter of potential risk factors. :)
Robert on Apr, 12, 2013:
I just wish the federal government would overhaul Richard Nixon's war on drugs and the whole controlled drug act. I have had my share of pain and you can consider yourself lucky to be able to cope with it. It is the sorry folk out there who have psychiatric disorders which affect the brain's ability to "deal" and cope, and is at a chemical level with them, a neurological mess-up. I know personally, I have phases of time when it is dangerous for me to try and tough it out when my brain sometimes slows down production and release of the natural chemicals like beta endorphin, dopamine, Gammaaminobuteric Acid, and I can find my body aches because Im not making enough natural opiate substances. SO I take drugs given by MD to make me feel normal, like clonazepam, prozac, and sometimes amphetamine in low doses. It is frustrating because people still don't understand and think I am a schmuck for taking drugs to feel normal happiness, calm, joy, relaxation, and to enjoy life's natural pleasures I periodically am unable to feel or appreciate.
Robert on Apr, 12, 2013:
It is true that speedballs, containing opiates and any stimulant. The "speed" in speedball likely refers to amphetamine, which was, prior to 1970, the original or at least most widely used upper in the 1960's. When the Controlled Drug Act was made official, cocaine became hugely popular, as an easier and more available alternative. SO strangely enough it became easier to get a totally outlawed drug than legal controlled drugs, because the new DEA and their most overzealous zealots were too busy finally settling old scores and getting the "dopeheads" and "speedfreeks" with the new Nixonian legislation backing them up like the word of God
Michele on Apr, 12, 2013:
I totally understand where you are coming from. Your comment at the end there helped me understand that I am not "a druggy" as my husband calls me because I need medications to feel an enjoy simple life activities. You're lucky to have found the right combination of medicines to treat your depression. I feel like I've been on a roller coaster for the last 20 years. If I find the "right" combination to treat my severe depression/bipolar2 disorders, then I find myself with one or more intolerable side effects that I must live with, like extreme teeth pain/bruxism. I look at people all the time and say to myself "That person is "normal." "That person is enjoying life." "That person sleeps normally and doesn't need help." "That person is a good mom for doing activities with her child/children." I get sorta jealous, then I start believing what my husband says about me being a druggy and that I am not a good teacher/mom/wife. That I shouldn't need medicine to just have energy to get up and get dressed. But when I read your post it made me feel good, not that you were dealing with depression, but that someone else out there understands how it feels, that my husband is dead wrong and out of line, that my depression is a real disorder and not my fault. Thank you for your post.
shannon on Apr, 13, 2013:
What shouldnt the expexation be...yes, cocaone is an antisthetic...only local, dentists "pink" mouth swab is cocaine based to numb the area and costrict blood vessels toz reduce swelling and bleeding....not for arthritis!..sounds like its a way to find a way out faster by destroying the heart muscle fro. The cocke's super stimulative effect and leave this world. There are other means to treat pain than death and mega doses of narcotics to mask the pain and increase the tolernance of the mds to the point that either there are no interior sinuses lrft by coke use or not enough pain meds to overcome the tolerance....ven IV cocaine use will burn the veins you shoot it in...its a loosing battle...and a painful one from damag thats beendone...Im praying for you guys...
Russ on May, 7, 2013:
Formally of you bashing the cocaine for pain, do some research! Brompton's Cocktail is a chronic pain medicine in liquid form that contains cocaine, opiates, and some other meds. It is an evidenced based treatment for chronic pain, so please don't assume just because it has cocaine in it means it's gonna kill you. People suffering from chronic.pain need relief. if Brompton's works, then let them get their much needed relief!!! Without judgement!!
I was in a MVA 2 1/2 years ago, I was an RN and was left unable to work. 3 months after the MVA I underwent a Hysterectomy found 4th grade Endometriosis with Adhesions. Only able to remove uterus, cervix is stuck to bowel unable to remove both ovaries retained. Underwent 2 rounds of 6 months each of Depro Lupron injections endometriosis symptoms subsided for 6-8 months and has since returned being cyclic for 12-15 days a month. During the time between the mva and hysterectomy 2 week period of stiffness, unable to move easily sent to rhuematologist found to recently had Parvo Recovered from that. Over time Rheumatologist diagnosed with connective tissue disorder started on Plaquenil and Prednisone. Diagnosed with Fibromyalgia. Sent to pain management diagnosed with pelvic floor tension myalgia, vuvlodynia, vaginal spasms, low testosterone and intersticial cystitis. Sent to sexual medicine doctor, found muscle damage from hysterectomy did trigger point injections and physical therapy deep tissue massage. Then I tore ACL and Medial Meniscus, unable to continue with pelvic pain doctor because gait was messing up what they were fixing. routine blood test found K+ to be 2.5 started on supplements of 40 meq a day of K+. Total body swelling started overnight started on Lasix, no improvement changed to Bumex edema decreased, potassium increased to 60 meq a day. I have been on pain medication since the MVA I have gone from Vicodin, valium to Percocet oxicontin, to MS Contin, Methadone, Butrans Patch and Now I am on Exalgo 12 mg once a day with 2 mg of dilaudid at bedtime. This does not seem to be working. I have constant abdominal/pelvic pain, vaginal spasms, bladder pain, kidney pain after the Bumex has worn off. I have developed Peripheral Neuropathy of my feet from taking crestor and hydroxychloroquine together, then they changed me to Lipitor, which is a statin and will do the same, Primary MD disagrees. I have suffered from Depression, anxiety, Panic attacks and migraines for over 10 years these are inherited conditions in Maternal Grandmother and Mother, migraines in Father also. They are now looking at Sjogrens Syndrome. Was on Vitamin B6 new medical journals say women should not take more than 10-50 mg a day-otc bottles say 100mg so pain management said I am suffering from vitamin B3 overdose and serotonin syndrome, trying to cut back on anti depressives and anti anxiety meds, but now is not really the time to do, I have been turned down for disability X2
Priti on May, 7, 2013:
Become a vegan, leave animal protein, do yoga and chant " Nam myoho renge Kyo". Search the website "Soka Gakkai International" , practice this philosophy and see the results.
Emm on Apr, 9, 2013:
It is highly unlikely that Lisinopril caused your cancer. You say you also take Atenolol. Both of these medications affect potassium levels in the blood. Altered potassium can cause muscle pain and cramping. The cancer also causes pain. If you are in remission make an appt ASAP. I pray for your recovery. Drink plenty of fluids, eat a mostly raw diet, and do all you can to stay well. Good luck.
amanda biggs on Aug, 31, 2012:
i have breast cancer and i was not feel well so went to doctor and they put me no penicillin vk are they shue it all right to take them
emelita on Mar, 24, 2011:
Yesterday I ask my pharmacy to print me a copy of all the medicine i have taken and he is kind enough to print me from 2005 to present 2011. I have seen that I have been on lisinopryl since or maybe as early as 2005 to 2009. On 2008 I have been diagnose with Uterus cancer so i have an extensive Hysterectomy. By the way all symptoms that I have at the time I am taking lisinopryl is the pain on my hips which I cannot walk much and sit much and stand much. I have always infections which wont go away. after the hysterectomy, the hips pains go away and the infections go away too. After that I change Doctor and he gave me a different HB pills. Now one week ago I started feeling the pain again after the Doctor change my medication So I started digging on what mediation I am taking that resulted of me having a cancer on the uterus and this lisinopryl is the culprit. lisinopryl. at that time I am also taking Atenolol 100 mg.
Aphasia, stroke like, M.S. like
MRI, negative
The problems with my lips began in Feb 2013. It is mostly my upper lip, with symptoms of tiny blisters & a red "line" along the edge of my upper lip, just the redness around my lower lip. There is also burning, swellin, and cracking of the upper lip. It will almost completely heal then will come back again. I thought it was an allrgic reaction to Cindy Crawford's Meaningful Beauty Anti-Aging Night Cream; I had been using it off & on and after a break of a few weeks I used it on my face and within 30 minutes my upper lip was swollen & burning. I have not used it in 2 weeks but the swelling, burning, and blisters started again. I was off of Cymbalta for part of those 2 weeks (thanks to a new insurance pharmacy plan), started back on it 5 days ago. I am wondering if it is the Cymbalta because of the side effect of "mouth sores".
Post a new comment OR Read more comments
Recent related drug studies:
- A study of drug interactions between Amlodipine, Lyrica, Vicodin, Percocet, Flexeril, Dilaudid, Skelaxin, Valium for a patient with Hypertension, Sciatica, Pain. The patient has Oedema Peripheral, Multiple Sclerosis Relapse, Joint Swelling, Intervertebral Disc Protrusion, Coma (Consciousness - decreased)
- A study of drug interactions between Amlodipine, Lyrica, Vicodin, Percocet, Dilaudid, Skelaxin, Flexeril, Valium for a patient with Hypertension, Sciatica, Pain. The patient has Oedema Peripheral, Multiple Sclerosis, Joint Swelling, Intervertebral Disc Protrusion, Coma (Consciousness - decreased)
NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
