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From FDA reports: drug interactions between Alendronate Sodium, Fosamax, Atenolol, Norvasc for a Female patient aged 65

This is a personalized study for a 65 year old female patient. The study is created by eHealthMe based on reports of 268 people who take the same drugs and have drug interactionsfrom FDA.

On Oct, 30, 2014: 268 people who reported to have interactions when taking Alendronate Sodium, Fosamax, Atenolol, Norvasc are studied

Trend of Alendronate Sodium, Fosamax, Atenolol, Norvasc's drug interactions, side effects, and effectiveness reports (7725992)

Information of the patient in this study:

Age: 65

Gender: female

Conditions: Osteoporosis, Blood Pressure

Drugs taking:
- Alendronate Sodium: used for 1 - 6 months
- Fosamax: used for 10+ years
- Atenolol
- Norvasc

Drug interactions have: Adverse Event, Renal Failure Chronic, Nocturia, Nephrosclerosis, Back Pain, Gingival Infection, Gingival Bleeding, Depression, Urinary Incontinence, Pollakiuria, Toothache, Impaired Healing, Blindness, Intervertebral Disc Degeneration, Sinus Disorder, Cataract, Aortic Calcification, Osteonecrosis Of Jaw, Arthritis, Strabismus, Dental Caries, Osteoarthritis, Urinary Retention, Tooth Infection, Major Depression, Hypercalcaemia, Road Traffic Accident, Adverse Drug Reaction, Amblyopia, Aortic Arteriosclerosis, Visual Acuity Reduced, Bladder Prolapse, Bladder Papilloma, Periodontitis, Tooth Disorder, Panic Disorder, Hypertonic Bladder, Oral Infection, Lower Limb Fracture, Anxiety, Breast Cancer, Excessive Granulation Tissue, Scoliosis, Nephropathy, Tooth Loss, Hypotension, Inguinal Hernia

eHealthMe real world results:

Comparison with this patient's adverse outcomes among females aged 65 (±5):

InteractionNumber of reports
Adverse Event12 (20.34%)
Renal Failure Chronic (long lasting kidney dysfunction)14 (23.73%)
Nocturia (the need to get up in the night to urinate)8 (13.56%)
Nephrosclerosis (hardening of the kidney due to renovascular disease)12 (20.34%)
Back Pain46 (77.97%)
Gingival Infection (gum infection)30 (50.85%)
Gingival Bleeding (bleeding gums)30 (50.85%)
Depression59 (100.00%)
Urinary Incontinence (inability to control the flow of urine and involuntary urination)4 (6.78%)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)8 (13.56%)
Toothache (tooth pain)28 (47.46%)
Impaired Healing54 (91.53%)
Blindness4 (6.78%)
Intervertebral Disc Degeneration (spinal disc degeneration)32 (54.24%)
Sinus Disorder (disease of sinus)30 (50.85%)
Cataract (clouding of the lens inside the eye)32 (54.24%)
Aortic Calcification (aortic calcification sign of heart valve disease)4 (6.78%)
Osteonecrosis Of Jaw (death of bone of jaw)59 (100.00%)
Arthritis (form of joint disorder that involves inflammation of one or more joints)44 (74.58%)
Strabismus (a disorder in which the two eyes do not line up in the same direction)4 (6.78%)
Dental Caries30 (50.85%)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)8 (13.56%)
Urinary Retention (the inability to completely or partially empty the bladder)12 (20.34%)
Tooth Infection (pus formation in tooth)59 (100.00%)
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)28 (47.46%)
Hypercalcaemia (elevated calcium (ca+) level in the blood)14 (23.73%)
Road Traffic Accident28 (47.46%)
Adverse Drug Reaction34 (57.63%)
Amblyopia (lazy eye)4 (6.78%)
Aortic Arteriosclerosis (hardening of the aortic arteries)32 (54.24%)
Visual Acuity Reduced (reduced clearness of vision)12 (20.34%)
Bladder Prolapse (bulging of one or more of the pelvic organs into the vagina)4 (6.78%)
Bladder Papilloma (bladder tumour)4 (6.78%)
Periodontitis (inflammation of the tissue around the teeth)24 (40.68%)
Tooth Disorder (tooth disease)59 (100.00%)
Panic Disorder29 (49.15%)
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate)4 (6.78%)
Oral Infection50 (84.75%)
Lower Limb Fracture4 (6.78%)
Anxiety59 (100.00%)
Breast Cancer34 (57.63%)
Excessive Granulation Tissue (excessive collagen-rich tissue which forms at the site of an injury)54 (91.53%)
Scoliosis (a medical condition in which a person's spine is curved from side to side)32 (54.24%)
Nephropathy (damage to or disease of a kidney)30 (50.85%)
Tooth Loss8 (13.56%)
Hypotension (abnormally low blood pressure)12 (20.34%)
Inguinal Hernia (hernia in which a loop of intestine enters the inguinal canal; the most common type of hernia in males)30 (50.85%)

Most common interactions experienced by females aged 65 (±5) in the use of Alendronate Sodium, Fosamax, Atenolol, Norvasc:

InteractionNumber of reports
Tooth Disorder (tooth disease)59
Osteonecrosis Of Jaw (death of bone of jaw)59
Depression59
Anxiety59
Tooth Infection (pus formation in tooth)59
Diarrhoea59
Mitral Valve Incompetence (inefficient heart valve)56
Impaired Healing54
Excessive Granulation Tissue (excessive collagen-rich tissue which forms at the site of an injury)54
Oral Infection50

Most common interactions experienced by females aged 65 (±5) in long term use of Alendronate Sodium, Fosamax, Atenolol, Norvasc:

InteractionNumber of reports
Osteonecrosis Of Jaw (death of bone of jaw)14
Tooth Disorder (tooth disease)14
Impaired Healing14
Depression14
Oral Infection14
Adverse Drug Reaction14
Arthritis (form of joint disorder that involves inflammation of one or more joints)14
Gingival Infection (gum infection)14
Gingival Bleeding (bleeding gums)14
Breast Cancer14

For people in general (regardless of gender or age):

Comparison with this patient's adverse outcomes:

InteractionNumber of reports
Adverse Event18 (6.72%)
Renal Failure Chronic (long lasting kidney dysfunction)50 (18.66%)
Nocturia (the need to get up in the night to urinate)14 (5.22%)
Nephrosclerosis (hardening of the kidney due to renovascular disease)12 (4.48%)
Back Pain62 (23.13%)
Gingival Infection (gum infection)30 (11.19%)
Gingival Bleeding (bleeding gums)30 (11.19%)
Depression103 (38.43%)
Urinary Incontinence (inability to control the flow of urine and involuntary urination)10 (3.73%)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)8 (2.99%)
Toothache (tooth pain)32 (11.94%)
Impaired Healing80 (29.85%)
Blindness4 (1.49%)
Intervertebral Disc Degeneration (spinal disc degeneration)32 (11.94%)
Sinus Disorder (disease of sinus)30 (11.19%)
Cataract (clouding of the lens inside the eye)36 (13.43%)
Aortic Calcification (aortic calcification sign of heart valve disease)4 (1.49%)
Osteonecrosis Of Jaw (death of bone of jaw)114 (42.54%)
Arthritis (form of joint disorder that involves inflammation of one or more joints)48 (17.91%)
Strabismus (a disorder in which the two eyes do not line up in the same direction)4 (1.49%)
Dental Caries30 (11.19%)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)28 (10.45%)
Urinary Retention (the inability to completely or partially empty the bladder)14 (5.22%)
Tooth Infection (pus formation in tooth)104 (38.81%)
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)28 (10.45%)
Hypercalcaemia (elevated calcium (ca+) level in the blood)20 (7.46%)
Road Traffic Accident28 (10.45%)
Adverse Drug Reaction34 (12.69%)
Amblyopia (lazy eye)4 (1.49%)
Aortic Arteriosclerosis (hardening of the aortic arteries)34 (12.69%)
Visual Acuity Reduced (reduced clearness of vision)14 (5.22%)
Bladder Prolapse (bulging of one or more of the pelvic organs into the vagina)4 (1.49%)
Bladder Papilloma (bladder tumour)4 (1.49%)
Periodontitis (inflammation of the tissue around the teeth)24 (8.96%)
Tooth Disorder (tooth disease)86 (32.09%)
Panic Disorder29 (10.82%)
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate)8 (2.99%)
Oral Infection54 (20.15%)
Lower Limb Fracture8 (2.99%)
Anxiety101 (37.69%)
Breast Cancer42 (15.67%)
Excessive Granulation Tissue (excessive collagen-rich tissue which forms at the site of an injury)54 (20.15%)
Scoliosis (a medical condition in which a person's spine is curved from side to side)36 (13.43%)
Nephropathy (damage to or disease of a kidney)48 (17.91%)
Tooth Loss8 (2.99%)
Hypotension (abnormally low blood pressure)54 (20.15%)
Inguinal Hernia (hernia in which a loop of intestine enters the inguinal canal; the most common type of hernia in males)30 (11.19%)

Most common interactions experienced by people in the use of Alendronate Sodium, Fosamax, Atenolol, Norvasc:

InteractionNumber of reports
Osteonecrosis Of Jaw (death of bone of jaw)114
Tooth Infection (pus formation in tooth)104
Depression103
Anxiety101
Diarrhoea89
Tooth Disorder (tooth disease)86
Impaired Healing80
Headache (pain in head)76
Nausea (feeling of having an urge to vomit)70
Mitral Valve Incompetence (inefficient heart valve)68

Most common interactions experienced by people in long term use of Alendronate Sodium, Fosamax, Atenolol, Norvasc:

InteractionNumber of reports
Impaired Healing29
Osteonecrosis Of Jaw (death of bone of jaw)29
Tooth Infection (pus formation in tooth)29
Tooth Disorder (tooth disease)29
Depression29
Oral Infection29
Oral Disorder (mouth disease)29
Pain In Jaw29
Adverse Drug Reaction29
Arthritis (form of joint disorder that involves inflammation of one or more joints)29

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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