A study of drug interactions between Effexor Xr, Metformin, Venlafaxine Hcl for a Female patient aged 65
This is a personalized study of Effexor Xr, Metformin, Venlafaxine Hcl drug interactions for a 65 year old female patient. The study is created by eHealthMe based on 2,518 reports from FDA.
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What are the drugs
Effexor xr has active ingredients of venlafaxine hydrochloride. It is used in depression, stress and anxiety, generalized anxiety disorder, major depression, dysthymia, depressed mood.
Metformin has active ingredients of metformin hydrochloride. It is used in diabetes, type 2 diabetes, polycystic ovary disease, insulin resistance, type 1 diabetes, type 1 diabetes mellitus .
Venlafaxine hcl has active ingredients of venlafaxine hydrochloride.
On Apr, 10, 2013: 2,518 people who reported to have interactions when taking Effexor Xr, Metformin, Venlafaxine Hcl are studied

Information of the patient in this study:
Age: 65
Gender: female
Conditions: Anxiety, Depression, Diabetes Mellitus
Drugs taking:
- Effexor Xr
- Effexor Xr
- Metformin
- Venlafaxine Hcl
Drug interactions have: Coronary Artery Occlusion, Cardiac Failure, Cardiac Operation, Drug Ineffective
eHealthMe real world results:
For females aged 65 (±5):
Comparison with this patient's adverse outcomes:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports |
| Coronary Artery Occlusion | 2 (0.61%) |
| Cardiac Failure | 4 (1.22%) |
| Cardiac Operation | 3 (0.91%) |
| Drug Ineffective | 15 (4.56%) |
Most common interactions experienced by females aged 65 (±5) in the use of Effexor Xr, Metformin, Venlafaxine Hcl:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports | |
| 1 | Diarrhoea | 58 |
| 2 | Vomiting | 47 |
| 3 | Nausea | 44 |
| 4 | Dyspnoea | 41 |
| 5 | Diabetes Mellitus | 39 |
| 6 | Pain | 28 |
| 7 | Renal Failure Acute | 27 |
| 8 | Dizziness | 26 |
| 9 | Bicytopenia | 25 |
| 10 | Blood Glucose Increased | 20 |
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Most common interactions experienced by females aged 65 (±5) in long term use of Effexor Xr, Metformin, Venlafaxine Hcl:
(click on each outcome to view in-depth analysis, incl. how people recovered)| None. |
For people in general (regardless of gender or age):
Comparison with this patient's adverse outcomes:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports |
| Coronary Artery Occlusion | 14 (0.56%) |
| Cardiac Failure | 39 (1.55%) |
| Cardiac Operation | 7 (0.28%) |
| Drug Ineffective | 100 (3.97%) |
Most common interactions experienced by people in the use of Effexor Xr, Metformin, Venlafaxine Hcl:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports | |
| 1 | Diabetes Mellitus | 634 |
| 2 | Anxiety | 469 |
| 3 | Type 2 Diabetes Mellitus | 431 |
| 4 | Diarrhoea | 354 |
| 5 | Dyspnoea | 352 |
| 6 | Nausea | 246 |
| 7 | Depression | 189 |
| 8 | Fatigue | 182 |
| 9 | Pain | 179 |
| 10 | Chest Pain | 175 |
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Most common interactions experienced by people in long term use of Effexor Xr, Metformin, Venlafaxine Hcl:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports | |
| 1 | Anxiety | 16 |
| 2 | Depression | 9 |
| 3 | Aortic Valve Stenosis | 8 |
| 4 | Mental Disorder | 7 |
| 5 | Pancreatitis Acute | 5 |
| 6 | Chest Pain | 5 |
| 7 | Paraesthesia | 4 |
| 8 | Pain | 4 |
| 9 | Multiple Congenital Abnormalities | 4 |
| 10 | Drug Exposure During Pregnancy | 4 |
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In-depth study of side effects (who have it, when it happens and how):
- Coronary Artery Occlusion in Effexor Xr (25 reports)
- Coronary Artery Occlusion in Metformin (387 reports)
- Cardiac Failure in Effexor Xr (62 reports)
- Cardiac Failure in Metformin (811 reports)
Could it be a symptom from a condition:
- Coronary Artery Occlusion in Anxiety (78 reports)
- Coronary Artery Occlusion in Depression (151 reports)
- Coronary Artery Occlusion in Diabetes Mellitus (603 reports)
- Cardiac Failure in Anxiety (198 reports)
- Cardiac Failure in Depression (530 reports)
- Cardiac Failure in Diabetes Mellitus (1,273 reports)
Drug effectiveness in real world:
- Effexor Xr for Anxiety reported by 199 people (updated 19 hours ago)
- Effexor Xr for Depression reported by 828 people (updated 6 days ago)
- Metformin for Diabetes Mellitus reported by 168 people (updated 12 hours ago)
Alternative drugs:
- Anxiety (141 drugs) (updated 10 hours ago)
- Depression (144 drugs) (updated 3 days ago)
- Diabetes Mellitus (59 drugs) (updated 12 hours ago)
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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
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