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From FDA reports: drug interactions between Januvia, Metformin, Gliclazide for a Male patient aged 62

This is a personalized study for a 62 year old male patient. The study is created by eHealthMe based on reports of 195 people who take the same drugs and have drug interactionsfrom FDA.

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On Sep, 18, 2014: 195 people who reported to have interactions when taking Januvia, Metformin, Gliclazide are studied

Trend of Januvia, Metformin, Gliclazide's drug interactions, side effects, and effectiveness reports (8702246)

Information of the patient in this study:

Age: 62

Gender: male

Conditions: Type 2 Diabetes Mellitus

Drugs taking:
- Januvia: used for 2 - 5 years
- Metformin
- Gliclazide

Drug interactions have: Macular Oedema, Visual Acuity Reduced, Phlebitis

eHealthMe real world results:

Comparison with this patient's adverse outcomes among males aged 62 (±5):

InteractionNumber of reports
Macular Oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken)4 (10.26%)
Visual Acuity Reduced (reduced clearness of vision)4 (10.26%)
Phlebitis (inflammation of the walls of a vein)4 (10.26%)

Most common interactions experienced by males aged 62 (±5) in the use of Januvia, Metformin, Gliclazide:

InteractionNumber of reports
Abdominal Pain Upper14
Oedema Peripheral (superficial swelling)12
Myalgia (muscle pain)12
Liver Function Test Abnormal10
Headache (pain in head)10
Constipation8
Rash (redness)8
Bone Pain8
Hyperglycaemia (high blood sugar)8
Blood Glucose Increased6

Most common interactions experienced by males aged 62 (±5) in long term use of Januvia, Metformin, Gliclazide:

InteractionNumber of reports
Hyperglycaemia (high blood sugar)2
Nausea (feeling of having an urge to vomit)2
Vertigo2
Prostate Cancer2

For people in general (regardless of gender or age):

Comparison with this patient's adverse outcomes:

InteractionNumber of reports
Macular Oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken)4 (2.05%)
Visual Acuity Reduced (reduced clearness of vision)4 (2.05%)
Phlebitis (inflammation of the walls of a vein)4 (2.05%)

Most common interactions experienced by people in the use of Januvia, Metformin, Gliclazide:

InteractionNumber of reports
Diarrhoea34
Myalgia (muscle pain)28
Hyperkalaemia (damage to or disease of the kidney)27
Oedema Peripheral (superficial swelling)22
Renal Failure Acute (rapid kidney dysfunction)22
Anuria (failure of the kidneys to produce urine)20
Abdominal Pain Upper20
Dyspepsia (indigestion)20
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)20
Drug Interaction20

Most common interactions experienced by people in long term use of Januvia, Metformin, Gliclazide:

InteractionNumber of reports
Nausea (feeling of having an urge to vomit)2
Hyperglycaemia (high blood sugar)2
Vertigo2
Prostate Cancer2
Lung Adenocarcinoma Metastatic (a form of non-small cell lung cancer spreads to other part)2
Lower Limb Fracture2

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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