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From FDA reports: side effects of Letrozole

This is a study of Letrozole side effects. The study is created by eHealthMe based on reports of 9,442 people who take the same drug and have side effectsfrom FDA.

On May, 13, 2015: 9,442 people who reported to have side effects when taking Letrozole are studied

Trend of Letrozole's drug interactions, side effects, and effectiveness reports (8221050)

Information of the patient in this study:

Gender: female

Conditions: Breast Cancer

Drugs taking:
- Letrozole

Side effects have: Spondylitic Myelopathy, Myelomalacia

eHealthMe real world results:

For people in general (regardless of gender or age):

Comparison with this patient's adverse outcomes:

Side effectNumber of reports
Spondylitic Myelopathy14 (0.15%)
Myelomalacia10 (0.11%)

Most common side effects experienced by people in the use of Letrozole:

Side effectNumber of reports
Bone Disorder2,290
Osteonecrosis Of Jaw2,222
Back Pain1,570

Most common side effects experienced by people in long term use of Letrozole:

Side effectNumber of reports
Bone Disorder168
Pain In Jaw142
Impaired Healing138
Metastases To Bone120
Osteonecrosis Of Jaw114

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:


Can you answer these questions (Ask a question):

  • Relief for severe nerve pain in hands?
    Just finished 2nd Zometa infusion (x 3 mos.) 2 weeks ago. Severe nerve pain in hands that have existing mild neuropathy. Will this go away?
  • My question is there are if studies and reports on the efficiency of this treatment?
    My mother is being treated against breast cancer for almost 20 years. There are about four years has been removed a breast and emptied (removed) the armpits. After she used only Xeloda Capecitabina 500 mg and soon after chemotherapy. At present she use Faslodex one time by month. Another doctor, sug ...
  • Plantar fasciitis and femara
    HELP!!! I have been on femara for 12 months, and at about 4 months I started getting plantar fasciitis. I now have plantar fasciitis in both feet and it is so painful that I am contemplating using a wheel chair. I cry daily from the pain, and sometimes wish I would just die. I was taking ibuprof ...

More questions for: Breast Cancer, Letrozole, Myelomalacia, Spondylitic Myelopathy

You may be interested at these reviews (Write a review):

  • Bone pain whilst taking letrozole
    Before having breast cancer I walked 10 miles a week, and did a 40 min exercise
    routine. Having had a lumpectomy followed by 15 radiation treatments, and then
    prescribed letrozole for 10 years, I can no longer do my 40 min exercise routine, nor the power walking that I have done for so ...
  • Victoza and breast cancer
    I took victoza for about 1 year. I have no history of breast cancer 9 my family.
  • Tinnitus with letrozole
    Sudden onset of ringing in the ears after two weeks on Letrozole 2.5mgs

More reviews for: Breast Cancer, Letrozole, Myelomalacia, Spondylitic Myelopathy

Complete side effects:

In-depth study of side effects (who have it, when it happens and how):

Drug effectiveness in real world:

Alternative drugs:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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