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From FDA reports: side effects of Letrozole

This is a study of Letrozole side effects. The study is created by eHealthMe based on reports of 9,442 people who take the same drug and have side effectsfrom FDA.

On Sep, 22, 2014: 9,442 people who reported to have side effects when taking Letrozole are studied

Trend of Letrozole's drug interactions, side effects, and effectiveness reports (8221050)

Information of the patient in this study:

Gender: female

Conditions: Breast Cancer

Drugs taking:
- Letrozole

Side effects have: Spondylitic Myelopathy, Myelomalacia

eHealthMe real world results:

For people in general (regardless of gender or age):

Comparison with this patient's adverse outcomes:

Side effectNumber of reports
Spondylitic Myelopathy (an inflammation of the vertebra)14 (0.15%)
Myelomalacia (softening and damage of the spinal cord due to some injury like compression by disc extrusion)10 (0.11%)

Most common side effects experienced by people in the use of Letrozole:

Side effectNumber of reports
Pain3,162
Anxiety2,421
Bone Disorder2,290
Osteonecrosis Of Jaw (death of bone of jaw)2,222
Arthralgia (joint pain)2,212
Fatigue (feeling of tiredness)1,947
Osteonecrosis (death of bone)1,816
Dyspnoea (difficult or laboured respiration)1,692
Nausea (feeling of having an urge to vomit)1,622
Back Pain1,570

Most common side effects experienced by people in long term use of Letrozole:

Side effectNumber of reports
Bone Disorder168
Pain In Jaw142
Pain140
Impaired Healing138
Osteomyelitis (infection of bone)136
Osteonecrosis (death of bone)136
Metastases To Bone (cancer spreads to bone)120
Arthralgia (joint pain)118
Osteonecrosis Of Jaw (death of bone of jaw)114
Swelling106

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Can you answer these questions (Ask a question):

  • Does femara affect crp results?
    (Asked by a 69 year old woman who has Cancer - Breast, and takes Femara)
    Does femara affect the results of the C Reactive Protein test? I have been on it for two years and have side effects of joint pain and hot flashes with nausea.

  • Breast cancer of former norplant users
    (Asked by a 47 year old woman who has Breast Cancer, and takes Norplant)
    Patients who had a norplant that developed breast cancer after it's removal. I know of 3 young women who have aggressive breast cancer and they all had norplant at some point.

  • What can i do to eliminate the pain and tenderness from superficicial thrombophlebitis in and under my breast
    (Asked by a 71 year old woman who has Superficial Thrombophlebitis, Breast Cancer)
    after breast cancer surgery, I developed superficial thrombophlebitis. Cannot wear a bra because any pressure froma band on a bra upon the rib cage right under my breast is painful. Any ideas for relief? Will time hopefully make this go away and the veins become less painful? Do I need to see a ...

More questions for: Breast Cancer, Letrozole, Myelomalacia, Spondylitic Myelopathy

You may be interested at these reviews (Write a review):

  • Bone pain whilst taking letrozole
    (Posted by a 70 year old woman who has Severe Bone Pain And Fatigue, and takes Letrozole)
    Before having breast cancer I walked 10 miles a week, and did a 40 min exercise routine. Having had a lumpectomy followed by 15 radiation treatments, and then prescribed letrozole for 10 years, I can no longer do my 40 min exercise routine, nor the power walking that I have done for so many years. ...

  • Victoza and breast cancer
    (Posted by a 44 year old woman who has Breast Cancer, and takes Victoza)
    I took victoza for about 1 year. I have no history of breast cancer 9 my family.

  • Tinnitus with letrozole
    (Posted by a 58 year old woman who has Ringing In The Ears, and takes Letrozole)
    Sudden onset of ringing in the ears after two weeks on Letrozole 2.5mgs

More reviews for: Breast Cancer, Letrozole, Myelomalacia, Spondylitic Myelopathy

Complete side effects:

In-depth study of side effects (who have it, when it happens and how):

Drug effectiveness in real world:

Alternative drugs:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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