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From FDA reports: drug interactions between Methotrexate, Prednisone, Mobic, Enbrel for a Female patient aged 52

This is a personalized study for a 52 year old female patient. The study is created by eHealthMe based on reports of 114 people who take the same drugs and have drug interactionsfrom FDA.

On Sep, 17, 2014: 114 people who reported to have interactions when taking Methotrexate, Prednisone, Mobic, Enbrel are studied

Trend of Methotrexate, Prednisone, Mobic, Enbrel's drug interactions, side effects, and effectiveness reports (7329517)

Information of the patient in this study:

Age: 52

Gender: female

Conditions: Psoriatic Arthropathy

Drugs taking:
- Methotrexate
- Prednisone
- Mobic
- Enbrel: used for 6 - 12 months

Drug interactions have: Lymphadenopathy, Pneumothorax, Sarcoidosis, Skin Nodule, Granuloma Skin

eHealthMe real world results:

Comparison with this patient's adverse outcomes among females aged 52 (±5):

InteractionNumber of reports
Lymphadenopathy (disease or enlargement of lymph nodes)6 (14.29%)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)2 (4.76%)
Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands)2 (4.76%)
Skin Nodule (slightly elevated lesions on or in the skin)2 (4.76%)
Granuloma Skin (a small area of inflammation on skin due to tissue injury)2 (4.76%)

Most common interactions experienced by females aged 52 (±5) in the use of Methotrexate, Prednisone, Mobic, Enbrel:

InteractionNumber of reports
Cellulitis (infection under the skin)42
Gastrooesophageal Reflux Disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)42
Tricuspid Valve Incompetence (inefficient heart valve)42
Pleural Effusion (water on the lungs)42
Osteoarthritis (a joint disease caused by cartilage loss in a joint)42
Exostosis (formation of new bone on the surface of a bone)42
Essential Thrombocythaemia (chronic blood cancer)42
Fatigue (feeling of tiredness)42
Foot Fracture42
Generalised Oedema (swelling all over the body)42

Most common interactions experienced by females aged 52 (±5) in long term use of Methotrexate, Prednisone, Mobic, Enbrel:

InteractionNumber of reports
Hyperkalaemia (damage to or disease of the kidney)2
Lymphadenopathy (disease or enlargement of lymph nodes)2
Malnutrition (condition that results from eating a diet in which certain nutrients are lacking)2
Lung Infection Pseudomonal (bacterial infection of lung by pseudomonas aeruginosa)2
Heart Valve Incompetence (heart's valves do not work correctly)2
Dermatitis Psoriasiform (large white or silver flakes on the skin)2
Gastrooesophageal Reflux Disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)2
Endocarditis Staphylococcal (an inflammation of the inner layer of the heart by staphylococcal bacterial infection)2
Drug Eruption (adverse drug reaction of the skin)2
Gastrointestinal Haemorrhage (bleeding gastrointestinal tract)2

For people in general (regardless of gender or age):

Comparison with this patient's adverse outcomes:

InteractionNumber of reports
Lymphadenopathy (disease or enlargement of lymph nodes)10 (8.77%)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)2 (1.75%)
Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands)2 (1.75%)
Skin Nodule (slightly elevated lesions on or in the skin)2 (1.75%)
Granuloma Skin (a small area of inflammation on skin due to tissue injury)2 (1.75%)

Most common interactions experienced by people in the use of Methotrexate, Prednisone, Mobic, Enbrel:

InteractionNumber of reports
Cellulitis (infection under the skin)84
Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)82
Pleural Effusion (water on the lungs)80
Diarrhoea80
Oedema Peripheral (superficial swelling)78
Uterine Leiomyoma (uterine benign tumour derived from smooth muscle)78
Osteoarthritis (a joint disease caused by cartilage loss in a joint)76
Osteoporosis (bones weak and more likely to break)76
Pain In Jaw76
Tricuspid Valve Incompetence (inefficient heart valve)76

Most common interactions experienced by people in long term use of Methotrexate, Prednisone, Mobic, Enbrel:

InteractionNumber of reports
Vomiting12
Nausea (feeling of having an urge to vomit)12
Candidiasis (candidiasis or thrush is a fungal infection)10
Weight Decreased8
Hypotension (abnormally low blood pressure)8
Pyrexia (fever)8
Uterine Leiomyoma (uterine benign tumour derived from smooth muscle)8
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)8
Decreased Appetite (decreased appetite occurs when you have a reduced desire to eat)8
Chest Pain8

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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