Topamax, Latuda, Klonopin for a 34-year old woman
Summary: 443 female patients aged 34 (±5) who take the same drugs are studied.
This is a personalized study for a 34 year old female patient who has Bipolar, Anxiety Disorder. The study is created by eHealthMe based on reports from FDA and social media.
What are the drugs
Topamax has active ingredients of topiramate. It is often used in migraine. (latest outcomes from Topamax 24,579 users)
Latuda has active ingredients of lurasidone hydrochloride. It is often used in bipolar ii disorder. (latest outcomes from Latuda 503 users)
Klonopin has active ingredients of clonazepam. It is often used in stress and anxiety. (latest outcomes from Klonopin 31,277 users)
What are the conditions
Bipolar (mood disorder) can be treated by Lamictal, Lithium Carbonate, Seroquel, Lamotrigine, Abilify, Depakote. (latest reports from Bipolar 43,111 patients)
Anxiety disorder (excessive, uncontrollable, unexplained and often irrational worry) can be treated by Xanax, Klonopin, Clonazepam, Lexapro, Zoloft, Ativan. (latest reports from Anxiety Disorder 15,910 patients)
On Nov, 28, 2014: 443 females aged 32 (±5) who take Topamax, Latuda, Klonopin are studied
Information of the patient in this study:
Conditions: Bipolar, Anxiety Disorder
- Topamax - 200MG (topiramate): used for 6 - 12 months
- Latuda - 80MG (lurasidone hydrochloride): used for 6 - 12 months
- Klonopin - 1MG (clonazepam): used for 1 - 6 months
eHealthMe real world results:
Drug effectiveness over time :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years||not specified|
|Topamax is effective||0.00%|
(0 of 3 people)
(0 of 1 people)
(0 of 1 people)
(1 of 5 people)
(4 of 7 people)
(2 of 2 people)
(1 of 3 people)
(0 of 2 people)
|Latuda is effective||n/a||100.00%|
(1 of 1 people)
|Klonopin is effective||0.00%|
(0 of 2 people)
(2 of 3 people)
(0 of 1 people)
(6 of 7 people)
(1 of 7 people)
(2 of 3 people)
(0 of 1 people)
(0 of 1 people)
Most common drug interactions over time * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years||not specified|
|Dyspnoea (difficult or laboured respiration)||Weight Increased||Asthenia (weakness)||Thyroid Nodule (a growth (lump) in the thyroid gland)||Psychotic Disorder||Nephrotic Syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema)||Impairment Of Speech (inability to speak (adult))||Nausea (feeling of having an urge to vomit)|
|Tongue Disorder (disease of tongue)||Postpartum Depression (depression suffered by a mother following childbirth)||Hepatic Enzyme Increased||Urinary Tract Infection||Gallbladder Injury||Intentional Overdose||Menopause (end of monthly cycles in women)||Completed Suicide (act of taking one's own life)|
|Non-accidental Overdose||Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)||Autoimmune Disorder (a condition in which the immune system attacks the body's normal substances and tissue)||Fatigue - Chronic (long feeling of tiredness)||Cholecystitis Chronic (long lasting infection of gallbladder)||Obsessive-compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)||Infertility Female||Headache (pain in head)|
|Muscle Spasms (muscle contraction)||Fatigue (feeling of tiredness)||Infertility Female||Hoarseness Or Changing Voice||Pain||Yellow Fever (acute viral circulation system bleeding disease)||Akathisia (a movement disorder characterized by a feeling of inner restlessness)||Pain|
|Oedema Peripheral (superficial swelling)||Dysarthria (speech disorder)||Sudden Hearing Loss||Sinusitis (inflammation of sinus)||Bipolar Disorder (mood disorder)||Exhaustion, Fatigue, Lethargy, Tiredness, Weariness (feeling of tiredness)||Short-term Memory Loss||Type 2 Diabetes Mellitus|
|Intraocular Pressure Increased||Chest Pain||Deafness Neurosensory||Swallowing Difficulty||Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)||Headache - Tension (head pain due to tension)||Autoimmune Disorder (a condition in which the immune system attacks the body's normal substances and tissue)||Diabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)|
|Vomiting||Dizziness||Menopause (end of monthly cycles in women)||Edema (excess of watery fluid collecting in the cavities or tissues of the body)||Injury||Suicide Attempt||Memory Impairment||Depression|
|Papilloedema (optic disc swelling)||Homicide (human killing another human)||Diabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)||Glucose Tolerance Impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)||Borderline Personality Disorder||Loss Of Consciousness||Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)|
|Poisoning||Disorientation (disability in which the senses of time, direction, and recognition of people and places)||Glucose Tolerance Impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)||Diabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)||Bile Duct Stone (stones in the common bile duct)||Feeling Hot And Cold||Weight Increased|
|White Blood Cell Count Increased||Depressed Mood||Dizziness||Movement Disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)||Memory Impairment||Foot, Leg, And Ankle Swelling||Vomiting|
* Some reports may have incomplete information.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
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- Join a related mobile support group
You are not alone! Join a related mobile support group:
- support group for people who have Anxiety Disorder
- support group for people who have Bipolar
- support group for people who take Klonopin
- support group for people who take Latuda
- support group for people who take Topamax
Can you answer these questions (Ask a question):
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I would like to start taking Garcinia Cambogia diet supplement colon cleansing regimen but I don't know if I can on these medications or not. Please help?
- Can nuvigil (vs adderall) be used simultaneously to help wean off 60mg/day of adderall? (1 answer)
I have been on Adderall 30mg 2x daily for years!! I've had it lowered to 20mg, I've TRIED to go months without it (when not working) however I feel I've built up a tolerance level to the point that it's not as effective as it once was. My personal life has detoured WAY past anything an ADHD medication can possibly help as far as focusing on NEEDED tasks etc. I end up feeling wrapped up in what I'm doing at the moment that my anxiety increases due to all that I haven't been able to accomplish. I take various medications for various reasons, depression, anxiety, bulimia etc., and for the most part the doses have varied based on circumstances and current need at said time of prescription.. MY FAMILY HAS A HISTORY OF HEART DISEASE, And realizing that I'm already on the highest Adderall dosage scares me (and THEN as I think about it, it makes my heart race!). I've also noticed increased muscle spasms as well as extreme and intense pressure on my jaw (TMJ). MY QUESTION IS: does anyone have any experience LOWERING their Adderall dosage AND adding Nuvigil? The research I've done to date gives me impression that it could help balance out the more extreme effects of Adderall (60mg/day) but that the nuvigil would or could potentially help with the EXTREME exhaustion I feel as Adderall wears off. Some days I just crash, some days I sleep fine and others no matter how hard I tryyyy, I just CAN'T fall asleep, therefore making the next day worse! IDEALLY I'D LIKE TO BE MED FREE, right now I need them, but am hoping maybe I can speak with my doctor to lower Adderall and add Nuvigil to help wean me off the amphetamines as well as lower dosage intake. YES, a lot of the anxiety, sleeplessness and depression are related to current circumstances in my life, however, where I am is not where I want to be or where I'm headed.. Life is a journey, and all my meds have become a part of a journey I never thought I'd find myself taking. I don't want life/meds to define me, or create a me I no longer recognize, because scarily enough that seems to be a common pattern. As I overcome each and every daily obstacle, I also don't want to be "hooked" on my meds or needing "more" to wake up/sleep/function.. I'd like to work on finding a solution towards weaning off my meds NOW, and work my way off slowly, primarily the Adderall. I'm hoping by suggesting to my doctor and showing him my research he may agree (IF ITS EVEN A LOGICAL COMBO, CLEARLY IM NOT A DOCTOR) nuvigil could help me. I've already started taking less of my anti depressants, trazadone and xanax without discussing with doc because he is always busy.. My next appt I want to go in fully prepared with a plan and an overall goal to REDUCE my Adderall dose, but overall, I'm clueless!!! I have no idea what other meds other than nuvigil "could" potentially help if at all. I could be entirely wrong, Anyone with any experience using one vs other or both simultaneously, or anyone with constructive input, PLEASE COMMENT/SHARE!!
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- A life of depression and fatigue
1) Family history of depression, 2) Diagnosed depression 1964-not treated until 1973, 3) Worked in medical field 35 years, 4) Emergency on-call 24/7, 5) Hospital 15 times major depression, 6) Tried nearly all MAOI, TCA, SSRI, SNRI, and ECT. 7) 100% Disability in 1998 for depression. Now at age 70 I have dysthymia, chronic fatigue, COPD, and PTSD. My recommendation to younger people - do not over stress,
do not smoke, avoid horrific or traumatic situations and try to find some enjoyment in life. If you have symptoms like mine seek early treatment put balance in your life. The often heard recommendations - get plenty of sleep, eat properly, learn to relax and avoid bad habits should not be ignored, they are critical to good physical and mental health.
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- 3 strong drugs together against neuropathic pain
Neuropathic pain debuted when I was 24, now I'm 50. Received diagnosed with Ehler-Danlos syndrome (EDS), joint hypermobility type, when I was 35 years old. So it can take some time to get a diagnose. And as EDS-patient I do not belong to any clinic. Orthopedics says that EDS is not orthopedic, rheumatology says that EDS is not an autoimmune disease, GPs say that EDS is too difficult, and so on. Sooner or later we all end up at Psychiatry, even if we are not depressed.
The first kind of pain I got when I was 24 came from low back, but I experienced as pelvic pain and leg pain. It was clearly a neuropathic pain, but it took years to find out. Later it was treated by a pain clinic with cortisone around the genitofemoral nerves (both sides). Since this treatment didn't result in lasting freedom from pain, the pain clinic started to give me RF (radio frequency) treatment. This made the pain disappeared after one year, and I was 80% free from it between 2002 and 2014, 12 years. The pain doctors said pain could return after 10 years.
The other kind of neuropathic pain started 2003 with intense stomach pain. During 6 months I could hardly eat nothing due to nausea and vomiting. After this 6 months, stomach pain changed to almost unbearable pain in upper back.
What happened 2003, and what all the doctors missed, was that the right lowest ribs slid up over the sternum. This rib dislocation is till there today, but now with a lot of cartilage formed around the rib where it is stuck in the lower end of the sternum. The dislocation is clearly visible on X-ray. This has greatly affected the thoracic spine. I have a scoliosis which I had not before 2003. And I still have severe pain in the thoracic spine.
It was initially treated with morphine daily, and later with Durogesic (fentanyl), but this didn't help much. 2005 I was hospitalized because I had too much pain to take care of myself and my hygiene. After some months the doctors started to give me clonazepam because the muscles along the spine was in a chronic seizures. Clonazepam helped, but I could still have a lot of pain in two vertebrae in the thoracic spine. It felt as if someone drilled into the vertebrae without anesthesia. After a few months, doctors also prescribed me methadone. Then the pain disappeared almost completely. Since 2006, I have eaten clonazepam and methadone every day, and I need to sleep in an armchair to not get more pain because of moving during sleep.
There are side effects. After 1,5 years with clonazepam and methadone I started to have panic attacks. Or rather one long panic attack which didn't stop before I got treatment with amitryptilin and pregabalin (Lyrica). These 2 medicines stopped the panic disorder completely after some hours, and the panic was then gone. Then I got side effects of these 2 medicines, amitryptilin & Lyrica, too. I gained a lot of weight (from 83 to 148 kg) and got much water (edema) in both my legs under the knees and in both feet. The feet could swallow to the double size. 2012 I stopped with amitryptilin and started to loose weight again (in Aug 2014 below 80 kg) and get less water in my legs. Today I eat as little medicines I can, but I have to take methadone, clonazepam and Lyrica every day, twice. If I try to take away one of these 3 medicines, I got pain problems at once. Lyrica is the most painful one to take away. In Sept-Dec 2013 I lowered Lyrica from 300 mg daily, to 150, then to 75 and finally 0 mg. The pain I had was extremely difficult to handle. It didn't help to take more methadone or anything else. I have checked on Internet and found that many people got pain from quitting with Lyrica. Most people start eating it again. So did I. But 2006 and 2007 it was enough to treat the pain with methadone and clonazepam, I got the Lyrica against anxiety not pain. But today I take Lyrica against pain.
Beside weight gain and leg edema, clonazepam and Lyrica significantly affect the sexual desire. And Lyrica alone makes it almost impossible to ejaculate. All four drugs together (clonazepam, methadone, amitryptiline and Lyrica), make one forget all about sex life. You don't even miss it. When I stopped with amitryptiline and lowered Lyrica (still taking clonazepam and methadone), I could suddenly easily get erections again, feel desire, but not getting orgasms. This is quite difficult to deal with.
The pain pattern is greatly affected, by pain and by the medicines. So is the mood. I get something which feels like heavy depression, especially if I take the medicines late that day. I should take a medicine like methadone 3 times a day, because the effects of the tablet lasts around 8 hours. But I take them every 12 hours, to have a low consumption in case doctors prescribe them too late (which happens, and then it's good to have a spouse going to the pharmacy buying them for you, because you have too much pain to go yourself).
Since methadone is also used for treating heroine addicts, medical staff treat you with disrespect when they see that it says "methadone" in your health record. I need to show a certificate that says that I deal with chronic neuropathic pain, that I never have had problems with drug addiction, to get normal respect.
I wanted to share this because I think I am alone in the world with these medicines in combination against neuropathic pain caused by hypermobile joints, joint dislocation and muscle spasms. After trying almost everything else, including surgery cutting nerves, methadone, clonazepam and Lyrica seems to be the only way to kill my pain. But it's a life where you always is questioned, because of the use of methadone. I can guarantee that everybody in the world should accept these medicines if they had experienced the unbearable pain I had in upper back before they started to give me clonazepam and methadone.
- Massive aggression within first 4 days at 50mg (1 response)
am only taking 50mg and have only been taking it for 4 days(this is the evening of the 4th day)as a preventative for migraine headaches that I have suffered from from 16 years. I have had pins and needles in my hands and feet as well as spontaneous crying fits since day 2 and Major aggression since yesterday. With normally an insurmountable amount of patience with my 1 year old son, I outright yelled at him last night. This is unacceptable. I have never felt such quick and sudden rage over nothing before, well, over anything before.
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I am a 48 yr old female diagnosed with PTSD, bipolar 2, BPD, histrionic suicidal idealation and a mess!!!
Things were going well in therapy and with my Dr. over the past 2 years on the above "cocktail" MINUS the Latuda and Lexapro.
I have had 3 very serious suicide attempts, all prior to the Tegretol /Prozac regime.
I do not want to change meds! Prior to the Tegretol, Klonopin , Lamictal , Prozac, Trazodone routine, I had made 3 very serious suicide attempts. The last leaving me with liver and kidney disease.
I've recently been left with two tragic yet situational on sets. So against my desire, I agreed to omit Prozac and replace with Lexapro and add Latuda, replacing Tegretol.
I have not been this unbalanced for YEARS! I know my triggers with suicide and believe that is the only reason I'm still alive. I HAD NOT THOUGHT ABOUT suicide for EIGHT YEARS!
Crying all the time, don't eat or sleep for sometimes, up to four days! I'm so tired, I just cry more from frustration of not being able to sleep.
I see my therapist tomorrow, but am on the "call" list for my Dr.
With the holidays among us, I do not nor do I think I can make it on these meds.
Can you PLEASE TELL ME if you know and I wasn't told, the, if any benefits will come forth? I know we are all different and I do trust my Md. Just not this time. Please, please help. Thank you.
Since starting Latuda I have noticed a sharp increase in the inability to tolerate bright light, especially sunlight.
I have experienced hearing loss within the past 8 years and wondered if it had to do with medications I have taken. I have taken others during that time including Abilify, Trileptal, Effexor. I recently have noticed a decrease in my hearing.
Related drug interaction studies:
Drug effectiveness in real world:
- Topamax for Bipolar reported by 43 people (updated 2 days ago)
- Latuda for Bipolar reported by 22 people (updated 8 hours ago)
- Klonopin for Anxiety Disorder reported by 491 people (updated 1 day ago)
Complete drug side effects:
- Anxiety Disorder (92 drugs in 5,511 reports) (updated 1 day ago)
- Bipolar (82 drugs in 3,287 reports) (updated 1 day ago)
NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
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