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Review: taking Acyclovir and Azithromycin together

Summary: drug interactions are reported among people who take Acyclovir and Azithromycin together.

This review analyzes the effectiveness and drug interactions between Acyclovir and Azithromycin. It is created by eHealthMe based on reports of 143 people who take the same drugs from FDA and social media, and is updated regularly.


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On Apr, 15, 2015: 143 people who take Acyclovir, Azithromycin are studied

Acyclovir, Azithromycin outcomes

Drug combinations in study:
- Acyclovir (acyclovir)
- Azithromycin (azithromycin)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Acyclovir is effective0.00%
(0 of 1 people)
(2 of 2 people)
(1 of 1 people)
Azithromycin is effective33.33%
(1 of 3 people)

Drug effectiveness by gender :

Acyclovir is effective66.67%
(2 of 3 people)
(1 of 1 people)
Azithromycin is effective0.00%
(0 of 2 people)
(1 of 1 people)

Drug effectiveness by age :

Acyclovir is effectiven/an/a0.00%
(0 of 1 people)
(1 of 1 people)
(1 of 4 people)
(1 of 1 people)
Azithromycin is effectiven/an/a0.00%
(0 of 1 people)
(0 of 1 people)
(1 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
VomitingElectrocardiogram Qt ProlongedSide Effectsn/an/aVomitingn/aEmotional Distress
PyrexiaNasal Septum PerforationPyrexiaArthralgia
Confusional StateDeathNauseaAnxiety
NauseaLiver Function Test AbnormalDepression
AstheniaHepatitisBack Pain
Liver Function Test AbnormalGeneral Physical Health DeteriorationHaemorrhoids
Csf Test AbnormalBronchitis
Viral Infection NosBlood Glucose Increased

Most common drug interactions by gender * :

ConstipationVomiting Nos
PainLiver Function Tests Nos Abnormal
AnxietyJaundice Nos
FatigueInternational Normalised Ratio Increased
Emotional DistressLoss Of Consciousness Nec
Blood Glucose IncreasedHepatic Failure
InjuryPulmonary Embolism
Gait DisturbanceSepsis Nos

Most common drug interactions by age * :

n/aPericardial EffusionBlood Lactate Dehydrogenase IncreasedStreptococcal Infection NosLymphadenopathyAlopeciaInjuryInjury
Blood Cortisol IncreasedAbdominal Pain UpperSinusitis NosVomiting NosAstheniaPainDizziness
Pitting OedemaBlood Glucose IncreasedRash Maculo-papularBack PainEmotional DistressAnxiety
Hepatitis NosDepressed Level Of ConsciousnessBronchitisDysuriaArthralgiaDyspepsia
Anaemia NosConvulsions NosArthralgiaDyskinesiaPyrexiaHeart Rate Increased
Tachycardia NosGrand Mal ConvulsionFatigueDiarrhoeaAnaemiaGingivitis
BlisterAggressionBlood Triglycerides IncreasedDepressionBack PainGait Disturbance
Neutrophil Count IncreasedBlood Creatinine IncreasedDepressionEmotional DistressPurulent DischargeHerpes Simplex
Epidermal NecrosisDiabetes MellitusBlood Glucose IncreasedGastrooesophageal Reflux DiseaseHaemorrhoidsLeukocytosis
DysphagiaNeuroleptic Malignant SyndromePruritusHypertensionOsteonecrosis Of JawLoss Of Consciousness

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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- support group for people who take Acyclovir
- support group for people who take Azithromycin

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Acyclovir (acyclovir) is often used to treat herpes simplex. Azithromycin (azithromycin) is often used to treat sinusitis. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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