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Home > Arava > Plaquenil > Arava and Plaquenil

Review: Arava and Plaquenil

This review analyzes the effectiveness and drug interactions between Arava and Plaquenil. It is created by eHealthMe based on reports of 1,913 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Arava and Plaquenil >>>

What are the drugs

Arava (latest outcomes from 16,324 users) has active ingredients of leflunomide. It is often used in rheumatoid arthritis.

Trend of arava reports

Plaquenil (latest outcomes from 15,510 users) has active ingredients of hydroxychloroquine sulfate. It is often used in rheumatoid arthritis.

Trend of plaquenil reports

On Oct, 29, 2014: 1,913 people who take Arava, Plaquenil are studied

Arava, Plaquenil outcomes

Drug combinations in study:
- Arava (leflunomide)
- Plaquenil (hydroxychloroquine sulfate)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Arava is effective0.00%
(0 of 4 people)
(1 of 12 people)
(0 of 3 people)
(0 of 1 people)
(2 of 9 people)
(0 of 2 people)
(1 of 3 people)
Plaquenil is effectiven/a33.33%
(2 of 6 people)
(0 of 4 people)
(1 of 6 people)
(3 of 14 people)
(0 of 5 people)
(0 of 4 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DiarrhoeaPneumoniaPelvic PainNauseaProgressive Multifocal LeukoencephalopathyGastritisAnorexiaPyrexia
PneumoniaLymphadenopathyVaginal HaemorrhagePneumoniaNauseaCardiac FailureAscitesArthralgia
Drug Exposure During PregnancyLung NeoplasmSquamous Cell Carcinoma Of The CervixVomitingVomitingGastrointestinal DisorderAbdominal DistensionNausea
Abdominal PainCellulitisCellulitisBeta Haemolytic Streptococcal InfectionHepatic CirrhosisRheumatoid ArthritisLymphedemaInjection Site Pain
Escherichia InfectionEscherichia InfectionNauseaCellulitisBlood Alkaline Phosphatase IncreasedMyocardial InfarctionWhite Blood Cell Count IncreasedRheumatoid Arthritis
Lung NeoplasmPseudomonas InfectionDrug Exposure During PregnancyHepatic FailureAscitesErythemaRheumatoid ArthritisInjection Site Erythema
Chest PainAppendicitis PerforatedBeta Haemolytic Streptococcal InfectionDyspnoeaHepatitis FulminantPainHepatic CirrhosisFatigue
Appendicitis PerforatedOvarian CystAppendicitis PerforatedPyrexiaDrug Exposure During PregnancyMental Status ChangesNauseaDrug Ineffective
VomitingNauseaEscherichia InfectionHypertensionColitis IschaemicConfusional StateBreast Cancer Stage IiDyspnoea
LymphadenopathyBeta Haemolytic Streptococcal InfectionHepatitis FulminantFatigueAstheniaWeight IncreasedBreast CancerDiarrhoea

Drug effectiveness by gender :

Arava is effective14.81%
(4 of 27 people)
(0 of 7 people)
Plaquenil is effective9.68%
(3 of 31 people)
(3 of 8 people)

Most common drug interactions by gender * :

NauseaDrug Ineffective
Injection Site PainFatigue
Rheumatoid ArthritisDyspnoea
Injection Site ErythemaArthralgia
FatigueMyocardial Infarction

Drug effectiveness by age :

Arava is effectiven/an/an/an/a18.18%
(2 of 11 people)
(1 of 6 people)
(0 of 19 people)
(1 of 11 people)
Plaquenil is effectiven/an/an/an/a8.33%
(1 of 12 people)
(1 of 7 people)
(1 of 22 people)
(3 of 12 people)

Most common drug interactions by age * :

n/an/aInjection Site UrticariaVaginal HaemorrhageDrug Exposure During PregnancyInjection Site ErythemaRheumatoid ArthritisArthralgia
Serum SicknessPelvic PainPyrexiaPyrexiaArthralgiaPneumonia
Drug Exposure During PregnancyDrug Exposure During PregnancyPregnancyNauseaInjection Site PainNausea
Injection Site RashSquamous Cell Carcinoma Of The CervixInjection Site PainFatigueDrug IneffectiveRheumatoid Arthritis
Injection Site PainHeadacheHypotensionDyspnoeaHeadachePyrexia
Injection Site HaemorrhageStaphylococcal AbscessDiarrhoeaInjection Site HaematomaDizzinessFall
DyspnoeaRenal Impairment NosGastroenteritisAlopeciaPainPancytopenia
Feeling HotSweating IncreasedMetabolic AcidosisInjection Site PainFatigueOedema Peripheral
Injection Site BurningTachycardia NosHypoxiaChest PainPyrexiaDyspnoea

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Arava and Plaquenil?

You are not alone! Join a related mobile support group:
- support group for people who take Arava and Plaquenil
- support group for people who take Arava
- support group for people who take Plaquenil

Can you answer these questions (Ask a question):

  • Can people with hypothyroidism take garcinia cambogia?
    (Asked by a 15 year old girl who has Idiopathic Thrombocytopenic Purpura, Hypothyroidism, Mixed Connective Tissue Disease, and takes Nabumetone, Levothyroxine Sodium, Prednisone, Plaquenil)
    I have hypothyroidism, ITP, and MCTD. With me having all of these issues and taking all these different medications, I was wondering if it would be safe for me to take a diet pill named garcinia cambogia.

  • So does hydroxychloroquine cause celiac desease?
    (Asked by a 47 year old man who has Been Tested Twice For Celiac And Was Always Negitive. Started Hydroxychloroquine And Was Removed Due To Blurring Vision. Tested Again For Celiac And Supposedly It's Now Positive And Causing My Authrit, and takes Hydroxychloroquine Sulfate)
    Been tested over the years for celiac and always negitive. Only had IBS. Took hydroxychloroquine for a year and it effected my vision. Then retested again for celiac because of authrits pain and now I'm positive for celiac.

  • What causes it? and why is it so painful?
    (Asked by a 45 year old woman who has Lupus, Shoulder Pain, and takes Plaquenil, Diclofenac Potassium)
    I can lift my arm out in front of me but not out to the side!! The diclofenac doesn't seem to help. Any suggestions? Has anyone been on benlysta?

  • Does xarelto contribute to extreme thinning of hair
    (Asked by a 72 year old woman who has Dry Eyes, Hypertension, Type 2 Diabetes, Atrial Fibrillation, and takes Glimepiride, Hydroxychloroquine Sulfate, Gabapentin, Pravastatin Sodium, Metformin, Lisinopril, Xarelto)
    extreme hair thinning inability to relieve dry eye symptoms (burning, feeling of foreign object in eyes can anything be done to correct these eymptoms

  • Interactions between quineprox (hydroxychloroquine) &zyvox (linezolid)
    (Asked by a 38 year old woman who has Headache, Fever, Swollen Fingers, Joint Pain, Muscle Tightness And Pain, and takes Zyvox, Cellcept)
    I had foot soft tissue infection and hospitalized for two days and given IV for Cipro. Then I was released from the hospital and given Zyvox 600MG twice a day for ten days. Meanwhile, I am taking 2000 MG cellcept and 400MG Hydroxychloriquine for more than 10 years to control my lupus. Around the si ...

More questions for: Arava, Plaquenil

You may be interested at these reviews (Write a review):

  • Had nms in 2005, will trileptal increase chance of recurrence?
    (Posted by a 62 year old woman who has Narcolepsy, Prinzmetal's Angina , Antiphospholipid Syndrome, High Blood Pressure, Obsessive-compulsive Personality Disorder, Cyclic Vomiting Syndrome, Migraine With Aura, Herniated Intervertebral Disk, Osteoarthritis, Fibromyalgia, Rheumatoid Arthritis, Diabetes Mellitus Insulin-dependent, Bipolar I Disorder, and takes Benadryl, Baclofen, Plaquenil, Nitro-bid, Maxalt-mlt, Imitrex, Zofran Odt, Ms Contin, Clonidine, Amlodipine Besylate, Novolog Flexpen, Levemir Flexpen, Halcion, Valium, Primidone, Neurontin, Trileptal)
    In 2005 I had NMS, which was not detected by my drs for 4 months. I'd been on Lexapro & Seroquel for 2 yrs, but was weaned from Lexapro & placed on Lamictal 3/05. Began getting low-grade fevers, which I was told were not caused by the Lamictal. I quit taking it anyway, fevers (along with uncontrolla ...

  • Spiriva caused me to swell up like a hippo.
    (Posted by a 46 year old woman who has Rheumatoid Arthritis, Irritable Bowel Syndrome, and takes Advair Diskus 250/50, Methotrexate, Plaquenil, Metformin, Klonopin, Zanaflex, Prednisone, Singulair, Imitrex, Nexium)
    My Doctor prescribed spiriva to help me breathe due to asthma/cold. I never smoked but my parents and friends were heavy smokers. I used the spiriva 3 times. Once a day for 3 days then I started swelling in my ankles and the swelling continued until my face, hands arms... basically I was so swollen ...

  • Plaquinil use shortness of breath
    (Posted by a 64 year old woman who has Osteoarthritis, and takes Plaquenil)
    Approximately 4 months after starting Plaquenil, I observed I was experiencing SOB while lifting the patient I was caring for, also had severe muscle weakness. I had been out of the country for several weeks and thought I might have picked up something while in The Dominican. I was also losing wei ...

More reviews for: Arava, Plaquenil

Complete drug side effects:

On eHealthMe, Arava (leflunomide) is often used to treat rheumatoid arthritis. Plaquenil (hydroxychloroquine sulfate) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug studies (Check your drugs):

More related studies for: Arava, Plaquenil

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

47 million health professionals and patients have studied on eHealthMe. Recent updates:

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