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Review: taking Aspirin and Aleve together

Summary: drug interactions are reported among people who take Aspirin and Aleve together.

This review analyzes the effectiveness and drug interactions between Aspirin and Aleve. It is created by eHealthMe based on reports of 1,887 people who take the same drugs from FDA and social media, and is updated regularly.


You are not alone: join a support group for people who take Aspirin and Aleve >>>

On Apr, 11, 2015: 1,887 people who take Aspirin, Aleve are studied

Aspirin, Aleve outcomes

Drug combinations in study:
- Aspirin (aspirin)
- Aleve (naproxen sodium)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Aspirin is effective66.67%
(2 of 3 people)
(1 of 3 people)
(3 of 4 people)
(3 of 5 people)
(4 of 8 people)
(5 of 14 people)
(4 of 10 people)
Aleve is effective33.33%
(2 of 6 people)
(4 of 8 people)
(2 of 8 people)
(5 of 11 people)
(5 of 9 people)
(4 of 8 people)
(3 of 4 people)

Drug effectiveness by gender :

Aspirin is effective46.43%
(13 of 28 people)
(9 of 19 people)
Aleve is effective41.38%
(12 of 29 people)
(13 of 25 people)

Drug effectiveness by age :

Aspirin is effectiven/an/an/a0.00%
(0 of 5 people)
(1 of 2 people)
(2 of 14 people)
(10 of 29 people)
(9 of 21 people)
Aleve is effectiven/an/an/a0.00%
(0 of 5 people)
(0 of 3 people)
(2 of 14 people)
(12 of 31 people)
(11 of 28 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DyspnoeaFatigueCerebrovascular AccidentLung Adenocarcinoma Stage IvLung Adenocarcinoma Stage IvGastric HaemorrhageHaemoglobin DecreasedPain
HypersensitivityContusionGait DisturbanceWeight IncreasedAbasiaGastric Ulcer HaemorrhageAbdominal PainAnxiety
DizzinessDyspnoeaHemiplegiaCerebrovascular AccidentMusculoskeletal DisorderGastric DisorderDiarrhoea HaemorrhagicBack Pain
PruritusDizzinessMaculeAbdominal PainDysstasiaGastric InfectionProtein UrineDizziness
PainUpper Gastrointestinal HaemorrhageContusionBlood Pressure IncreasedDrug IneffectiveGastric UlcerColitisPain In Extremity
ErythemaVision BlurredDyspnoeaConfusionCoronary Artery OcclusionIntestinal PolypRenal DisorderArthralgia
HeadacheHeadacheRenal DisorderHyperlipidemiaArthropathyLoss Of ConsciousnessScarNausea
DiarrhoeaDysgeusiaScabAltered State Of ConsciousnessBack DisorderHaematocheziaDry MouthDyspnoea
Pain In ExtremityFallBlisterBronchitis NosChest PainDifficulty In WalkingCardiac DiscomfortFall
Chest PainMyocardial InfarctionPollakiuriaBleeding Time ProlongedPalpitationsDry MouthDry EyeOedema Peripheral

Most common drug interactions by gender * :

Back PainDyspnoea
Pain In ExtremityFatigue
Oedema PeripheralVomiting
NauseaMyocardial Infarction

Most common drug interactions by age * :

n/an/aDeep Vein ThrombosisInjuryPain In ExtremityPainPainPain
Neck PainPainChest PainAnxietyAnxietyAsthenia
Vith Nerve ParalysisAbdominal PainDeep Vein ThrombosisDizzinessBack PainDyspnoea
PainPelvic PainBack PainNauseaInjuryFatigue
Intracranial Venous Sinus ThrombosisDysuriaOedema PeripheralDepressionChest PainDizziness
Periorbital OedemaMicturition UrgencyDyspnoeaDiabetes MellitusHypoaesthesiaArthralgia
General Physical Health DeteriorationNephrolithiasisMyocardial InfarctionWeight IncreasedDyspnoeaPain In Extremity
InjuryBack PainBlood Cholesterol IncreasedDiarrhoeaPyrexiaFall
Mental DisorderOedema PeripheralPulmonary EmbolismArthralgiaAnhedoniaBack Pain
Pulmonary EmbolismRashAnxietyHypertensionPain In JawAnxiety

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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- support group for people who take Aleve
- support group for people who take Aspirin

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Aspirin (aspirin) is often used to treat blood clots. Aleve (naproxen sodium) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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