eHealthMe - Personalized health information & community eHealthMe - Personalized health information & community

Personalized health information & community

All drugs: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
All conditions: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Check symptoms   -   Check drugs   -   Compare drugs   -   Join a support group   -   More tools

Review: taking Benadryl and Clonazepam together

Summary: drug interactions are reported among people who take Benadryl and Clonazepam together.

This review analyzes the effectiveness and drug interactions between Benadryl and Clonazepam. It is created by eHealthMe based on reports of 1,476 people who take the same drugs from FDA and social media, and is updated regularly.


You are not alone: join a support group for people who take Benadryl and Clonazepam >>>

On Apr, 16, 2015: 1,476 people who take Benadryl, Clonazepam are studied

Benadryl, Clonazepam outcomes

Drug combinations in study:
- Benadryl (diphenhydramine hydrochloride)
- Clonazepam (clonazepam)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Benadryl is effective31.58%
(6 of 19 people)
(5 of 12 people)
(6 of 10 people)
(5 of 11 people)
(5 of 12 people)
(6 of 15 people)
(6 of 10 people)
(2 of 2 people)
Clonazepam is effective26.67%
(4 of 15 people)
(4 of 16 people)
(2 of 7 people)
(4 of 5 people)
(10 of 23 people)
(11 of 17 people)
(9 of 12 people)
(2 of 2 people)

Drug effectiveness by gender :

Benadryl is effective44.29%
(31 of 70 people)
(10 of 21 people)
Clonazepam is effective46.67%
(35 of 75 people)
(11 of 22 people)

Drug effectiveness by age :

Benadryl is effectiven/an/a66.67%
(2 of 3 people)
(8 of 21 people)
(10 of 57 people)
(8 of 53 people)
(11 of 38 people)
(2 of 10 people)
Clonazepam is effectiven/an/a50.00%
(2 of 4 people)
(8 of 23 people)
(12 of 57 people)
(8 of 56 people)
(13 of 38 people)
(3 of 10 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
HeadacheDepressionShort-term Memory LossHeart Rate IncreasedInjuryArthritisItchingPain
HypotensionPathological GamblingBlood Triglycerides IncreasedHigh Blood PressureCholelithiasisPseudoporphyriaDizzinessNausea
Bk Virus InfectionPseudoporphyriaExhaustion, Fatigue, Lethargy, Tiredness, WearinessStomach PainPainFatigue - ChronicBack Pain AggravatedDepression
Cystitis HaemorrhagicInflammationHigh Blood SugarPerimenopauseBipolar DisorderMemory LossAccidental DeathAnxiety
HyperbilirubinaemiaArthritisWeight Gain - UnintentionalTeeth Grinding And ClenchingItchingConstipationAortic Valve StenosisHeadache
SepsisHomicideSweating - ExcessiveInability To CrawlItching - Burning EyesDepressionLightheadednessFall
Cytomegalovirus InfectionHeart Rate IncreasedDrowsinessDisorientationStressUrine Flow DecreasedChronic PainInsomnia
Mucosal InflammationDysarthriaDiarrhoeaNeutrophil Count IncreasedMuscle TwitchingAnxietyDermatitis AcneiformDyspnoea
DehydrationAbortion SpontaneousFeeling JitteryLymphocyte Count DecreasedAngerFacial PainHot FlashesFatigue
Suicidal IdeationFacial Nerve PalsyLymphocyte Count DecreasedExcessive SkinInability To CrawlItchingSweating IncreasedWeight Increased

Most common drug interactions by gender * :

HeadacheWeight Increased
Weight IncreasedBack Pain

Most common drug interactions by age * :

Pulmonary HypertensionSuicidal IdeationSuicidal IdeationInsomniaNauseaHeadacheFallPain
Urethral StenosisDehydrationWeight IncreasedUrinary Tract InfectionDiabetes MellitusDepressionPainHypertension
Weight IncreasedGrand Mal ConvulsionNauseaNauseaAnxietyPainAnxietyDepression
Type 2 Diabetes MellitusSepsisAbdominal Pain UpperVomitingVomitingFallDepressionAnxiety
Obstruction GastricHypotensionFatigueAstheniaChest PainSuicidal IdeationCoughFatigue
Myocarditis Post InfectionViral InfectionWeight DecreasedPericardial EffusionPainNauseaInsomniaNausea
NephrolithiasisDisease ProgressionPyrexiaAbdominal Pain UpperDyspnoeaDyspnoeaPain In ExtremityAnaemia
PancreatitisDrug Administration ErrorHeadacheDyspnoeaCompleted SuicideAnxietyNauseaInsomnia
ConvulsionDepressionAnaemiaDizzinessBack PainPyrexiaDyspnoea
Stevens-johnson SyndromeDrug Withdrawal SyndromeUpper Respiratory Tract InfectionMuscle SpasmsHypotensionInjuryFall

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of Benadryl and Clonazepam on

Do you take Benadryl and Clonazepam?




You are not alone! Join a related support group:
- support group for people who take Benadryl
- support group for people who take Clonazepam

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Benadryl (diphenhydramine hydrochloride) is often used to treat allergies. Clonazepam (clonazepam) is often used to treat stress and anxiety. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


About - Terms of service - Privacy policy - Press - Testimonials - Contact us -

© 2015 All rights reserved. Use of this site constitutes acceptance of's terms of service and privacy policy.