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Review: Benadryl and Cogentin

This review analyzes the effectiveness and drug interactions between Benadryl and Cogentin. It is created by eHealthMe based on 357 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

On Apr, 2, 2014: 357 people who reported to have interactions when taking Benadryl, Cogentin are studied

Trend of Benadryl, Cogentin's drug interactions, side effects and effectiveness reports (3179053)

Drug combinations in study:
- Benadryl (diphenhydramine hydrochloride)
- Cogentin (benztropine mesylate)

eHealthMe real world results:

Most common interactions experienced by people in the use of Benadryl, Cogentin:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Diabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)165
Type 2 Diabetes Mellitus91
Nausea (feeling of having an urge to vomit)76
Dizziness74
Tardive Dyskinesia (a disorder that involves involuntary movements)72
Fatigue (feeling of tiredness)70
Tremor (trembling or shaking movements in one or more parts of your body)69
Depression68
Extrapyramidal Disorder (involuntary muscle spasms in the face and neck)63
Headache (pain in head)58

Most common interactions experienced by people in long term use of Benadryl, Cogentin:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Agitation Aggravated (state of anxiety or nervous excitement)3
Respiratory Arrest (cessation of normal respiration due to failure of the lungs to function effectively)3
Respiratory Failure (inadequate gas exchange by the respiratory system)3
Coma (state of unconsciousness lasting more than six hours)3
Flushed2
Aggression Aggravated2
Hyperactivity Syndrome Aggravated2
Drug Interaction Nos2
Drug Toxicity Nos2
Foreign Body Trauma (injury by foreign particle)2

How effective are the drugs:

not at allsomewhatmoderatehighvery high
Benadryl0.000.000.000.000.00
Cogentin0.00%100.00%0.00%0.00%0.00%

Top conditions involved for these people * :

  1. Bipolar disorder
  2. Schizophrenia
  3. Depression
  4. Anxiety
  5. Agitation

Top co-used drugs for these people * :

  1. Seroquel
  2. Zyprexa
  3. Risperdal
  4. Haldol
  5. Diphenhydramine hcl

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Benadryl, Cogentin

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Complete drug side effects:

On eHealthMe, Benadryl (diphenhydramine hydrochloride) is often used to treat allergies. Cogentin (benztropine mesylate) is often used to treat tardive dyskinesia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Can you answer these questions (what is this?):

More questions for: Benadryl, Cogentin

You may be interested at these reviews (what is this?):

  • Leg pain and occasional arm and hand pain
    I started having leg pains at night, lower leg felt like the muscle and bone were being pulled causing sharp pain. It was relieved by getting up and walking but would last most of the night. I finally realized after suffering this over and over for months, that it only happened when I had taken be ...

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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