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Review: Benadryl and Librium

This review analyzes the effectiveness and drug interactions between Benadryl and Librium. It is created by eHealthMe based on reports of 78 people who take the same drugs from FDA and social media, and is updated regularly.

Get connected: join a mobile support group for people who take Benadryl and Librium >>>

What are the drugs

Benadryl (latest outcomes from 29,348 users) has active ingredients of diphenhydramine hydrochloride. It is often used in allergies.

Librium (latest outcomes from 1,672 users) has active ingredients of chlordiazepoxide hydrochloride. It is often used in stress and anxiety.

On Sep, 27, 2014: 78 people who take Benadryl, Librium are studied

Benadryl, Librium outcomes

Drug combinations in study:
- Benadryl (diphenhydramine hydrochloride)
- Librium (chlordiazepoxide hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Benadryl is effective0.00%
(0 of 2 people)
(1 of 1 people)
(1 of 1 people)
(0 of 1 people)
Librium is effective33.33%
(1 of 3 people)
(1 of 2 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Animal Biten/an/aWithdrawal Syndromen/an/aWithdrawal SyndromePain
Fungal InfectionTachycardiaTachycardiaFall
PruritusWeight LossWeight LossHeadache
Rash MacularEustachian Tube DysfunctionEustachian Tube DysfunctionInsomnia
Rash PapularVomiting
Diabetes Mellitus
Decreased Appetite

Drug effectiveness by gender :

Benadryl is effective50.00%
(1 of 2 people)
(0 of 2 people)
Librium is effective66.67%
(2 of 3 people)
(0 of 2 people)

Most common drug interactions by gender * :

VomitingDiabetes Mellitus
NauseaCompleted Suicide
Weight DecreasedAsthenia
Suicidal IdeationPancreatitis Acute
InsomniaDrug Ineffective

Drug effectiveness by age :

Benadryl is effectiven/an/an/a25.00%
(1 of 4 people)
(0 of 5 people)
Librium is effectiven/an/an/a33.33%
(1 of 3 people)
(0 of 5 people)
(1 of 1 people)

Most common drug interactions by age * :

n/an/an/aDeliriumComa NecDry MouthInsomniaPain
Completed SuicideMydriasisHepatic SteatosisPainFatigue
Neuroleptic Malignant SyndromeTachycardiaHepatitisFallParaesthesia
Polysubstance DependenceCompleted SuicideHepatosplenomegalyDrug IneffectiveHypoaesthesia
PharyngitisAbdominal DiscomfortHepatic CirrhosisMuscle SpasmsHeadache
Schizoaffective DisorderBronchitisHeadacheDyspnoeaVomiting
Vaginal HaemorrhageChronic Obstructive Pulmonary DiseaseDizzinessDiarrhoeaDizziness
Neck PainDepressionGastritisDecreased AppetiteFall
Suicidal IdeationCoughHyperkalaemiaHypoaesthesiaOverdose

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Benadryl and Librium?

Get connected! Join a related mobile support group:
- support group for people who take Benadryl and Librium
- support group for people who take Benadryl
- support group for people who take Librium

Comments from related studies:

  • From this study (2 years ago):

  • The length of time I've struggled with sleep disorders has resulted in higher than normal Benadryl usage, but I wake up every day (after only a few hours of sleep) with my ears feeling plugged now. Benadryl is the only thing I have found to relieve the pressure, increasing my usage of the drug even more.


Can you answer these questions (what is this?):

More questions for: Benadryl, Librium

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  • Leg pain and occasional arm and hand pain
    I started having leg pains at night, lower leg felt like the muscle and bone were being pulled causing sharp pain. It was relieved by getting up and walking but would last most of the night. I finally realized after suffering this over and over for months, that it only happened when I had taken be ...

More reviews for: Benadryl, Librium

Complete drug side effects:

On eHealthMe, Benadryl (diphenhydramine hydrochloride) is often used to treat allergies. Librium (chlordiazepoxide hydrochloride) is often used to treat stress and anxiety. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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