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Review: taking Benadryl and Zofran together

Summary: drug interactions are reported among people who take Benadryl and Zofran together.

This review analyzes the effectiveness and drug interactions between Benadryl and Zofran. It is created by eHealthMe based on reports of 746 people who take the same drugs from FDA and social media, and is updated regularly.

 

You are not alone: join a support group for people who take Benadryl and Zofran >>>

On Mar, 26, 2015: 746 people who take Benadryl, Zofran are studied

Benadryl, Zofran outcomes

Drug combinations in study:
- Benadryl (diphenhydramine hydrochloride)
- Zofran (ondansetron hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Benadryl is effective60.00%
(3 of 5 people)
100.00%
(2 of 2 people)
n/an/a0.00%
(0 of 2 people)
100.00%
(1 of 1 people)
n/a0.00%
(0 of 1 people)
Zofran is effective25.00%
(1 of 4 people)
100.00%
(3 of 3 people)
50.00%
(1 of 2 people)
n/a100.00%
(1 of 1 people)
100.00%
(1 of 1 people)
n/a0.00%
(0 of 1 people)

Drug effectiveness by gender :

FemaleMale
Benadryl is effective66.67%
(6 of 9 people)
0.00%
(0 of 2 people)
Zofran is effective70.00%
(7 of 10 people)
0.00%
(0 of 2 people)

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Benadryl is effectiven/an/an/a33.33%
(1 of 3 people)
10.53%
(2 of 19 people)
66.67%
(2 of 3 people)
4.00%
(1 of 25 people)
0.00%
(0 of 2 people)
Zofran is effectiven/an/an/a33.33%
(1 of 3 people)
5.26%
(1 of 19 people)
66.67%
(2 of 3 people)
8.00%
(2 of 25 people)
33.33%
(1 of 3 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
PyrexiaFebrile NeutropeniaConstipationn/aNephrogenic Systemic FibrosisBurning Eyesn/aNausea
DehydrationSepsisAnaemiaConstipationVomiting
HyperglycaemiaCaecitisNausea And VomitingCardiac ArrestPyrexia
PneumoniaPneumoniaThrombocytopeniaNauseaPain
HypotensionEscherichia InfectionEsophageal Stricture - BenignHeadacheAnxiety
DizzinessClostridial InfectionNeoplasm MalignantLethargyDiarrhoea
DyspnoeaEnterococcal BacteraemiaPneumoniaDepressionDehydration
Platelet Count DecreasedRespiratory FailureTumour EmbolismSkin Burning SensationHypotension
AnorexiaBacterial Test PositiveColitisAnxiety, Apprehension, Feeling Uptight, Jitters, Stress, Stress And Anxiety, TensionHeadache
Neutrophil Count DecreasedDermatitis AcneiformRenal FailureChronic PancreatitisFatigue

Most common drug interactions by gender * :

FemaleMale
NauseaPyrexia
VomitingHypotension
AnxietyDehydration
HeadachePneumonia
Urinary Tract InfectionPain
HypertensionVomiting
PainDiarrhoea
NeutropeniaNausea
PyrexiaFatigue
DiarrhoeaFebrile Neutropenia

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
ConstipationVomitingNauseaRenal FailureNauseaVomitingNauseaDiarrhoea
VomitingPleural EffusionHypotensionMulti-organ FailurePainPyrexiaPyrexiaNausea
Ejection Fraction DecreasedFebrile NeutropeniaVomitingSupraventricular TachycardiaHaemoglobin DecreasedNauseaNeutropeniaHypotension
Left Ventricular HypertrophyLymphadenopathyHeadacheInfluenza Like IllnessPyrexiaFatigueVomitingDehydration
HypoxiaDiarrhoeaHypersensitivityBronchitisHyperglycaemiaNeck PainAnaemiaFall
Oxygen Saturation DecreasedIrritabilityHodgkin's DiseaseCholecystitisVomitingChest PainFallFebrile Neutropenia
PyrexiaNauseaBlood Bilirubin IncreasedSinusitisDehydrationPainDyspnoeaUrinary Tract Infection
WheezingAbdominal PainRenal Failure AcuteCardiac Failure CongestiveCellulitisAstheniaDehydrationAsthenia
TachypnoeaFibrin D Dimer IncreasedPyrexiaInsomniaOedema PeripheralBack PainPneumoniaPneumonia
RashCystitis HaemorrhagicLymphadenopathyUrinary Tract InfectionHeadacheAnxietyRespiratory FailureSepsis

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Benadryl and Zofran?

 

 

 

You are not alone! Join a related support group:
- support group for people who take Benadryl
- support group for people who take Zofran

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Benadryl (diphenhydramine hydrochloride) is often used to treat allergies. Zofran (ondansetron hydrochloride) is often used to treat nausea. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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