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Review: Benadryl and Zofran

This review analyzes the effectiveness and drug interactions between Benadryl and Zofran. It is created by eHealthMe based on reports of 741 people who take the same drugs from FDA and social media, and is updated regularly.

Get connected: join a mobile support group for people who take Benadryl and Zofran >>>

What are the drugs

Benadryl (latest outcomes from 29,335 users) has active ingredients of diphenhydramine hydrochloride. It is often used in allergies.

Zofran (latest outcomes from 869 users) has active ingredients of ondansetron hydrochloride. It is often used in nausea.

On Sep, 14, 2014: 741 people who take Benadryl, Zofran are studied

Benadryl, Zofran outcomes

Drug combinations in study:
- Benadryl (diphenhydramine hydrochloride)
- Zofran (ondansetron hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Benadryl is effective50.00%
(2 of 4 people)
100.00%
(2 of 2 people)
n/an/an/an/an/a0.00%
(0 of 1 people)
Zofran is effective25.00%
(1 of 4 people)
100.00%
(3 of 3 people)
n/an/an/an/an/a0.00%
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
PyrexiaFebrile NeutropeniaTumour Embolismn/aNephrogenic Systemic Fibrosisn/an/aNausea
DehydrationSepsisPneumoniaCardiac ArrestVomiting
HyperglycaemiaCaecitisNeoplasm MalignantPyrexia
PneumoniaPneumoniaRenal FailurePain
HypotensionEscherichia InfectionThrombocytopeniaAnxiety
DizzinessClostridial InfectionAnaemiaDiarrhoea
Platelet Count DecreasedEnterococcal BacteraemiaHypotension
AnorexiaRespiratory FailureDehydration
DyspnoeaBacterial Test PositiveHeadache
CoughDermatitis AcneiformFatigue

Drug effectiveness by gender :

FemaleMale
Benadryl is effective80.00%
(4 of 5 people)
0.00%
(0 of 2 people)
Zofran is effective66.67%
(4 of 6 people)
0.00%
(0 of 2 people)

Most common drug interactions by gender * :

FemaleMale
NauseaPyrexia
VomitingHypotension
AnxietyDehydration
HeadachePneumonia
Urinary Tract InfectionNausea
PainVomiting
HypertensionDiarrhoea
NeutropeniaPain
DiarrhoeaFatigue
PyrexiaFebrile Neutropenia

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Benadryl is effectiven/an/an/a33.33%
(1 of 3 people)
20.00%
(1 of 5 people)
50.00%
(1 of 2 people)
100.00%
(1 of 1 people)
0.00%
(0 of 2 people)
Zofran is effectiven/an/an/a33.33%
(1 of 3 people)
0.00%
(0 of 5 people)
50.00%
(1 of 2 people)
100.00%
(1 of 1 people)
33.33%
(1 of 3 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
ConstipationVomitingNauseaRenal FailureNauseaVomitingPyrexiaDiarrhoea
VomitingPleural EffusionHypotensionMulti-organ FailurePainNauseaNauseaNausea
Ejection Fraction DecreasedFebrile NeutropeniaVomitingSupraventricular TachycardiaPyrexiaPyrexiaNeutropeniaHypotension
Left Ventricular HypertrophyLymphadenopathyHeadacheInfluenza Like IllnessHaemoglobin DecreasedFatigueVomitingDehydration
HypoxiaDiarrhoeaHypersensitivityBronchitisVomitingNeck PainAnaemiaFall
Oxygen Saturation DecreasedIrritabilityHodgkin's DiseaseCholecystitisDehydrationChest PainFallFebrile Neutropenia
PyrexiaNauseaBlood Bilirubin IncreasedSinusitisCellulitisAstheniaDehydrationUrinary Tract Infection
WheezingAbdominal PainRenal Failure AcuteCardiac Failure CongestiveHyperglycaemiaPainDyspnoeaAsthenia
TachypnoeaFibrin D Dimer IncreasedPyrexiaInsomniaHeadacheBack PainPneumoniaPneumonia
RashCystitis HaemorrhagicLymphadenopathyUrinary Tract InfectionOedema PeripheralAnxietyFatigueAnxiety

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Benadryl and Zofran?

Get connected! Join a mobile support group:
- group for people who take Benadryl and Zofran
- group for people who take Benadryl
- group for people who take Zofran

Comments from related studies:

  • From this study (2 years ago):

  • have had red itchy inflamation {rash like} swelling of throat and tongue shortness of breath chest pain numbness of fingers and toes feels cold then hot iv drip dry cough possible latex allergy uncontrollable belching

    Reply

  • From this study (3 years ago):

  • My patient has a milky white substance oozing spontaneously from his implanted port site after the infusion of pepcid, benadryl, zofran, and decadron followed by Cetuximab. Has this been reported before?

    Reply

  • From this study (5 years ago):

  • THIS DRUG CAUSED DERMATOMYOSITIS AND SEVERE PAIN,RASH AND MUSCLE WEAKNESS.

    Reply

Can you answer these questions (what is this?):

More questions for: Benadryl, Zofran

You may be interested at these reviews (what is this?):

  • Leg pain and occasional arm and hand pain
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  • I got pneumonia while taking topamax, obvious correlation
    I do not take all the medicines above all the time but I am using an implanted pump giving me less than 2mg of dilaudid per day, 75 mg effexor daily and usually buspar. Dr prescribed topamax within 4 days I was hospitalized with Pneumonia, stayed a week came home a week had a clear chest x ray and ...

More reviews for: Benadryl, Zofran

Complete drug side effects:

On eHealthMe, Benadryl (diphenhydramine hydrochloride) is often used to treat allergies. Zofran (ondansetron hydrochloride) is often used to treat nausea. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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