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Home > Benadryl > Zofran > Benadryl and Zofran

Review: Benadryl and Zofran

Summary: drug interactions are reported among people who take Benadryl and Zofran together.

This review analyzes the effectiveness and drug interactions between Benadryl and Zofran. It is created by eHealthMe based on reports of 745 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Benadryl and Zofran >>>

What are the drugs

Benadryl (latest outcomes from 29,359 users) has active ingredients of diphenhydramine hydrochloride. It is often used in allergies.

Trend of benadryl reports

Zofran (latest outcomes from 882 users) has active ingredients of ondansetron hydrochloride. It is often used in nausea.

Trend of zofran reports

On Nov, 25, 2014: 745 people who take Benadryl, Zofran are studied

Benadryl, Zofran outcomes

Drug combinations in study:
- Benadryl (diphenhydramine hydrochloride)
- Zofran (ondansetron hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Benadryl is effective60.00%
(3 of 5 people)
100.00%
(2 of 2 people)
n/an/a0.00%
(0 of 1 people)
100.00%
(1 of 1 people)
n/a0.00%
(0 of 1 people)
Zofran is effective25.00%
(1 of 4 people)
100.00%
(3 of 3 people)
50.00%
(1 of 2 people)
n/an/a100.00%
(1 of 1 people)
n/a0.00%
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
PyrexiaFebrile NeutropeniaConstipationn/aCardiac ArrestBurning Eyesn/aNausea
DehydrationSepsisAnaemiaNephrogenic Systemic FibrosisVomiting
HyperglycaemiaCaecitisNausea And VomitingStomach PainPyrexia
PneumoniaPneumoniaThrombocytopeniaConstipationPain
HypotensionEscherichia InfectionEsophageal Stricture - BenignNauseaAnxiety
DizzinessClostridial InfectionNeoplasm MalignantDrug IneffectiveDiarrhoea
DyspnoeaEnterococcal BacteraemiaPneumoniaDehydration
Platelet Count DecreasedRespiratory FailureTumour EmbolismHypotension
AnorexiaBacterial Test PositiveColitisHeadache
Neutrophil Count DecreasedDermatitis AcneiformRenal FailureFatigue

Drug effectiveness by gender :

FemaleMale
Benadryl is effective75.00%
(6 of 8 people)
0.00%
(0 of 2 people)
Zofran is effective66.67%
(6 of 9 people)
0.00%
(0 of 2 people)

Most common drug interactions by gender * :

FemaleMale
NauseaPyrexia
VomitingHypotension
AnxietyDehydration
HeadachePneumonia
HypertensionPain
PainVomiting
Urinary Tract InfectionDiarrhoea
NeutropeniaNausea
DiarrhoeaFatigue
PyrexiaFebrile Neutropenia

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Benadryl is effectiven/an/an/a33.33%
(1 of 3 people)
10.53%
(2 of 19 people)
66.67%
(2 of 3 people)
100.00%
(1 of 1 people)
0.00%
(0 of 2 people)
Zofran is effectiven/an/an/a33.33%
(1 of 3 people)
5.26%
(1 of 19 people)
66.67%
(2 of 3 people)
100.00%
(1 of 1 people)
33.33%
(1 of 3 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
ConstipationVomitingNauseaRenal FailureNauseaVomitingPyrexiaDiarrhoea
VomitingPleural EffusionHypotensionMulti-organ FailurePainPyrexiaNauseaNausea
Ejection Fraction DecreasedFebrile NeutropeniaVomitingSupraventricular TachycardiaHaemoglobin DecreasedNauseaNeutropeniaHypotension
Left Ventricular HypertrophyLymphadenopathyHeadacheInfluenza Like IllnessPyrexiaFatigueVomitingDehydration
HypoxiaDiarrhoeaHypersensitivityBronchitisHyperglycaemiaNeck PainAnaemiaFall
Oxygen Saturation DecreasedIrritabilityHodgkin's DiseaseCholecystitisVomitingChest PainFallFebrile Neutropenia
PyrexiaNauseaBlood Bilirubin IncreasedSinusitisDehydrationPainDehydrationUrinary Tract Infection
WheezingAbdominal PainRenal Failure AcuteCardiac Failure CongestiveCellulitisAstheniaDyspnoeaAsthenia
TachypnoeaFibrin D Dimer IncreasedPyrexiaInsomniaOedema PeripheralBack PainPneumoniaPneumonia
RashCystitis HaemorrhagicLymphadenopathyUrinary Tract InfectionHeadacheAnxietyFatigueSepsis

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Benadryl and Zofran?

You are not alone! Join a related mobile support group:
- support group for people who take Benadryl and Zofran
- support group for people who take Benadryl
- support group for people who take Zofran

Can you answer these questions (Ask a question):

More questions for: Benadryl, Zofran

You may be interested at these reviews (Write a review):

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  • Benadryl completed suicide 50 year old
    (Posted by a 50 year old woman who has Completed Suicide, and takes Alcohol, Methenamine Hippurate, Xanax, Benadryl)
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    (Posted by a 62 year old woman who has Narcolepsy, Prinzmetal's Angina , Antiphospholipid Syndrome, High Blood Pressure, Obsessive-compulsive Personality Disorder, Cyclic Vomiting Syndrome, Migraine With Aura, Herniated Intervertebral Disk, Osteoarthritis, Fibromyalgia, Rheumatoid Arthritis, Diabetes Mellitus Insulin-dependent, Bipolar I Disorder, and takes Benadryl, Baclofen, Plaquenil, Nitro-bid, Maxalt-mlt, Imitrex, Zofran Odt, Ms Contin, Clonidine, Amlodipine Besylate, Novolog Flexpen, Levemir Flexpen, Halcion, Valium, Primidone, Neurontin, Trileptal)
    In 2005 I had NMS, which was not detected by my drs for 4 months. I'd been on Lexapro & Seroquel for 2 yrs, but was weaned from Lexapro & placed on Lamictal 3/05. Began getting low-grade fevers, which I was told were not caused by the Lamictal. I quit taking it anyway, fevers (along with uncontrolla ...

  • Leg pain and occasional arm and hand pain
    (Posted by a 69 year old woman who has Lower Leg Pain, and takes Benadryl)
    I started having leg pains at night, lower leg felt like the muscle and bone were being pulled causing sharp pain. It was relieved by getting up and walking but would last most of the night. I finally realized after suffering this over and over for months, that it only happened when I had taken be ...

  • I got pneumonia while taking topamax, obvious correlation
    (Posted by a 44 year old woman who has Plantar Fasciitis, Trigger Finger, Anemia - B12 Deficiency, Anemia, Malabsorption, Gastric Bypass, Osteopenia, Chronic Pancreatitis, Depression, and takes Klonopin, Ambien Cr, Prilosec Otc, Zenpep, Calcium, Zinc Sulfate, Vitamin D, Vitamin A, Job's-tears, Vitamin B12, Zofran, Zantac, Zyrtec, Doxycycline Hyclate, Reclast, Venofer, Neurontin, Buspar, Effexor, Dilaudid)
    I do not take all the medicines above all the time but I am using an implanted pump giving me less than 2mg of dilaudid per day, 75 mg effexor daily and usually buspar. Dr prescribed topamax within 4 days I was hospitalized with Pneumonia, stayed a week came home a week had a clear chest x ray and ...

More reviews for: Benadryl, Zofran

Complete drug side effects:

On eHealthMe, Benadryl (diphenhydramine hydrochloride) is often used to treat allergies. Zofran (ondansetron hydrochloride) is often used to treat nausea. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug studies (Check your drugs):

More related studies for: Benadryl, Zofran

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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