eHealthMe - FDA and Social Media, Personalized eHealthMe - FDA and Social Media, Personalized

FDA and Social Media, Personalized

Drugs A-Z       Conditions A-Z       Health Tools       Health Community
Home > Benadryl > Zofran > Benadryl and Zofran

Review: Benadryl and Zofran

This review analyzes the effectiveness and drug interactions between Benadryl and Zofran. It is created by eHealthMe based on reports of 743 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Benadryl and Zofran >>>

What are the drugs

Benadryl (latest outcomes from 29,348 users) has active ingredients of diphenhydramine hydrochloride. It is often used in allergies.

Zofran (latest outcomes from 875 users) has active ingredients of ondansetron hydrochloride. It is often used in nausea.

On Oct, 26, 2014: 743 people who take Benadryl, Zofran are studied

Benadryl, Zofran outcomes

Drug combinations in study:
- Benadryl (diphenhydramine hydrochloride)
- Zofran (ondansetron hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Benadryl is effective50.00%
(2 of 4 people)
(2 of 2 people)
(0 of 1 people)
(1 of 1 people)
(0 of 1 people)
Zofran is effective25.00%
(1 of 4 people)
(3 of 3 people)
(0 of 1 people)
(1 of 1 people)
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
PyrexiaFebrile NeutropeniaRenal Failuren/aCardiac ArrestBurning Eyesn/aNausea
DehydrationSepsisNeoplasm MalignantNephrogenic Systemic FibrosisVomiting
HyperglycaemiaCaecitisTumour EmbolismStomach PainPyrexia
HypotensionEscherichia InfectionThrombocytopeniaNauseaAnxiety
DizzinessClostridial InfectionAnaemiaDrug IneffectiveDiarrhoea
Platelet Count DecreasedEnterococcal BacteraemiaNauseaHypotension
AnorexiaRespiratory FailureConstipationDehydration
DyspnoeaBacterial Test PositiveStomach PainHeadache
CoughDermatitis AcneiformDrug IneffectiveFatigue

Drug effectiveness by gender :

Benadryl is effective71.43%
(5 of 7 people)
(0 of 2 people)
Zofran is effective62.50%
(5 of 8 people)
(0 of 2 people)

Most common drug interactions by gender * :

Urinary Tract InfectionVomiting
DiarrhoeaFebrile Neutropenia

Drug effectiveness by age :

Benadryl is effectiven/an/an/a33.33%
(1 of 3 people)
(1 of 9 people)
(2 of 3 people)
(1 of 1 people)
(0 of 2 people)
Zofran is effectiven/an/an/a33.33%
(1 of 3 people)
(0 of 9 people)
(2 of 3 people)
(1 of 1 people)
(1 of 3 people)

Most common drug interactions by age * :

ConstipationVomitingNauseaRenal FailureNauseaVomitingPyrexiaDiarrhoea
VomitingPleural EffusionHypotensionMulti-organ FailurePainPyrexiaNauseaNausea
Ejection Fraction DecreasedFebrile NeutropeniaVomitingSupraventricular TachycardiaHaemoglobin DecreasedNauseaNeutropeniaHypotension
Left Ventricular HypertrophyLymphadenopathyHeadacheInfluenza Like IllnessPyrexiaFatigueVomitingDehydration
HypoxiaDiarrhoeaHypersensitivityBronchitisCellulitisNeck PainAnaemiaFall
Oxygen Saturation DecreasedIrritabilityHodgkin's DiseaseCholecystitisVomitingChest PainFallFebrile Neutropenia
PyrexiaNauseaBlood Bilirubin IncreasedSinusitisHyperglycaemiaPainDehydrationUrinary Tract Infection
WheezingAbdominal PainRenal Failure AcuteCardiac Failure CongestiveDehydrationAstheniaDyspnoeaAsthenia
TachypnoeaFibrin D Dimer IncreasedPyrexiaInsomniaOedema PeripheralBack PainPneumoniaPneumonia
RashCystitis HaemorrhagicLymphadenopathyUrinary Tract InfectionHeadacheAnxietyFatigueAnxiety

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Benadryl and Zofran?

Get connected! Join a related mobile support group:
- support group for people who take Benadryl and Zofran
- support group for people who take Benadryl
- support group for people who take Zofran

Comments from related studies:

  • From this study (2 weeks ago):

  • Possible stomach blockage, pharmaceutical bezoar.
    Oxycontin 30 mg every 12 hours is far less effective than oxycodone 15 mg every 6 hours.


  • From this study (2 years ago):

  • have had red itchy inflamation {rash like} swelling of throat and tongue shortness of breath chest pain numbness of fingers and toes feels cold then hot iv drip dry cough possible latex allergy uncontrollable belching


  • From this study (3 years ago):

  • My patient has a milky white substance oozing spontaneously from his implanted port site after the infusion of pepcid, benadryl, zofran, and decadron followed by Cetuximab. Has this been reported before?


Post a new comment    OR    Read more comments

Can you answer these questions (what is this?):

More questions for: Benadryl, Zofran

You may be interested at these reviews (what is this?):

  • Benadryl completed suicide 50 year old
    My mother comitted suicide by taking a bottle of Benadryl. She also had been drinking, she had taken xanax and drank beer, she also took 300 Benadryl pills and started having seizures and went to the hospital was brain dead and her heart stopped the next morning.

  • Had nms in 2005, will trileptal increase chance of recurrence?
    In 2005 I had NMS, which was not detected by my drs for 4 months. I'd been on Lexapro & Seroquel for 2 yrs, but was weaned from Lexapro & placed on Lamictal 3/05. Began getting low-grade fevers, which I was told were not caused by the Lamictal. I quit taking it anyway, fevers (along with uncontrolla ...

  • Leg pain and occasional arm and hand pain
    I started having leg pains at night, lower leg felt like the muscle and bone were being pulled causing sharp pain. It was relieved by getting up and walking but would last most of the night. I finally realized after suffering this over and over for months, that it only happened when I had taken be ...

More reviews for: Benadryl, Zofran

Complete drug side effects:

On eHealthMe, Benadryl (diphenhydramine hydrochloride) is often used to treat allergies. Zofran (ondansetron hydrochloride) is often used to treat nausea. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

44 million health professionals and patients have studied on eHealthMe. Recent studies:

- Venlafaxine Hydrochloride, Prazosin Hydrochloride for a 46-year old woman who has Depression, PTSD (3 minutes ago)

- Lexapro for a 44-year old woman who has Anxiety (30 minutes ago)

- Zoloft for a 52-year old woman who has Depression (38 minutes ago)


Recent mobile support groups

- Mirena and Coagulopathy

- Slapped Cheek

- Abdominal Pain and Premarin

- Ringing In The Ears and Ribavirin

- Gerd and Stomach Discomfort


Recent user comments

- "It has been almost two months that abovementoined sym ... " (58 minutes ago)

- "Wondering if possible i could have candida. i have ce ... " (2 hours ago)

- "Within a week after starting Meloxicam I developed a ... " (2 hours ago)


Recent searches

- Acetyl L Carnitine
- Portal Vein Occlusion
- Nopal
- Prelone
- Polysporin


About - Terms of service - Privacy policy - Press - Testimonials - Contact us

© 2014 All rights reserved. Use of this site constitutes acceptance of's terms of service and privacy policy.