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Related topic: Benadryl, Zofran

Review: Benadryl and Zofran

This review analyzes the effectiveness and drug interactions between Benadryl and Zofran. It is created by eHealthMe based on 723 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Mar, 30, 2014: 723 people who reported to have interactions when taking Benadryl, Zofran are studied

Trend of Benadryl, Zofran's drug interactions, side effects and effectiveness reports (3339980)

Drug combinations in study:
- Benadryl (diphenhydramine hydrochloride)
- Zofran (ondansetron hydrochloride)

eHealthMe real world results:

Most common interactions experienced by people in the use of Benadryl, Zofran:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Vomiting361
Pyrexia (fever)354
Anxiety311
Diarrhoea272
Nausea (feeling of having an urge to vomit)266
Pain197
Fatigue (feeling of tiredness)164
Dehydration (dryness resulting from the removal of water)164
Anaemia (lack of blood)153
Headache (pain in head)152

Most common interactions experienced by people in long term use of Benadryl, Zofran:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Nephrogenic Systemic Fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)4
Cardiac Arrest4
Decubitus Ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)3
Coagulopathy (blood's ability to clot is impaired)3
Central Line Infection (infection by central line in icu)2
Hypercalcaemia (elevated calcium (ca+) level in the blood)2
Headache (pain in head)2
Eye Infection2
Grand Mal Convulsion (a type of generalized seizure that affects the entire brain)2
Discomfort2

How effective are the drugs:

not at allsomewhatmoderatehighvery high
Benadryl50.00%0.00%0.00%0.00%50.00%
Zofran0.00%0.00%100.00%0.00%0.00%

Top conditions involved for these people * :

  1. Premedication
  2. Nausea
  3. Prophylaxis
  4. Pain
  5. Acute myeloid leukaemia

Top co-used drugs for these people * :

  1. Acetaminophen
  2. Diphenhydramine hcl
  3. Lorazepam
  4. Dexamethasone
  5. Potassium chloride

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Complete drug side effects:

On eHealthMe, Benadryl (diphenhydramine hydrochloride) is often used to treat allergen. Zofran (ondansetron hydrochloride) is often used to treat nausea. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (1 year ago):

  • have had red itchy inflamation {rash like} swelling of throat and tongue shortness of breath chest pain numbness of fingers and toes feels cold then hot iv drip dry cough possible latex allergy uncontrollable belching

    Reply

  • From this study (2 years ago):

  • My patient has a milky white substance oozing spontaneously from his implanted port site after the infusion of pepcid, benadryl, zofran, and decadron followed by Cetuximab. Has this been reported before?

    Reply

  • From this study (5 years ago):

  • THIS DRUG CAUSED DERMATOMYOSITIS AND SEVERE PAIN,RASH AND MUSCLE WEAKNESS.

    Reply

Can you answer these questions (what is this?):

More questions for: Benadryl, Zofran

You may be interested at these reviews (what is this?):

  • Leg pain and occasional arm and hand pain
    I started having leg pains at night, lower leg felt like the muscle and bone were being pulled causing sharp pain. It was relieved by getting up and walking but would last most of the night. I finally realized after suffering this over and over for months, that it only happened when I had taken be ...

  • I got pneumonia while taking topamax, obvious correlation
    I do not take all the medicines above all the time but I am using an implanted pump giving me less than 2mg of dilaudid per day, 75 mg effexor daily and usually buspar. Dr prescribed topamax within 4 days I was hospitalized with Pneumonia, stayed a week came home a week had a clear chest x ray and ...

More reviews for: Benadryl, Zofran

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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