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Review: Bupropion and Lithium Carbonate

This review analyzes the effectiveness and drug interactions between Bupropion and Lithium Carbonate. It is created by eHealthMe based on reports of 1,224 people who take the same drugs from FDA and social media, and is updated regularly.

Get connected: join a mobile support group for people who take Bupropion and Lithium Carbonate >>>

What are the drugs

Bupropion hydrochloride (latest outcomes from 6,652 users) has active ingredients of bupropion hydrochloride. It is often used in depression.

Lithium carbonate (latest outcomes from 16,021 users) has active ingredients of lithium carbonate. It is often used in bipolar disorder.

On Sep, 16, 2014: 1,224 people who take Bupropion Hydrochloride, Lithium Carbonate are studied

Bupropion Hydrochloride, Lithium Carbonate outcomes

Drug combinations in study:
- Bupropion Hydrochloride (bupropion hydrochloride)
- Lithium Carbonate (lithium carbonate)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Bupropion Hydrochloride is effective41.67%
(5 of 12 people)
(4 of 17 people)
(2 of 15 people)
(8 of 20 people)
(13 of 34 people)
(9 of 15 people)
(4 of 10 people)
(0 of 1 people)
Lithium Carbonate is effective0.00%
(0 of 10 people)
(6 of 16 people)
(4 of 7 people)
(10 of 23 people)
(17 of 28 people)
(10 of 17 people)
(13 of 19 people)
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Suicidal IdeationSuicidal IdeationType 2 Diabetes MellitusType 2 Diabetes MellitusType 2 Diabetes MellitusGait AbnormalHypertensionDiabetes Mellitus
NauseaType 2 Diabetes MellitusSuicidal IdeationWeight IncreasedDiabetes MellitusDrug ToxicityLibido DecreasedType 2 Diabetes Mellitus
Weight IncreasedDiabetes MellitusInflammationPancreatitis AcuteHypoglycaemiaDehydrationDiarrhoeaDepression
Pericardial EffusionHepatitis CBacterial InfectionDiabetes MellitusAltered State Of ConsciousnessConfusional StateProgressive Renal FailureWeight Increased
Bipolar DisorderPericardial EffusionHysterectomyOverdoseTremorSchizoaffective DisorderDiabetes MellitusNausea
Type 2 Diabetes MellitusTremorGastric UlcerParanoiaNauseaLethargyConstipation AggravatedAnxiety
Suicide AttemptBlood Cholesterol IncreasedBladder DisorderTardive DyskinesiaMemory ImpairmentParanoiaAkathisiaTremor
AngerMemory ImpairmentFungal InfectionSuicidal IdeationOsteoporosisPsychomotor HyperactivityDissociationSuicidal Ideation
Oedema PeripheralHyperglycaemiaDiabetes MellitusBlood Glucose IncreasedHypersomniaCondition AggravatedAnxiety AggravatedFatigue
Venous InsufficiencyDepressionHeadacheDrug IneffectiveVomitingMemory ImpairmentDiabetic NeuropathyInsomnia

Drug effectiveness by gender :

Bupropion Hydrochloride is effective40.00%
(32 of 80 people)
(13 of 43 people)
Lithium Carbonate is effective48.10%
(38 of 79 people)
(22 of 42 people)

Most common drug interactions by gender * :

NauseaDiabetes Mellitus
DepressionType 2 Diabetes Mellitus
Diabetes MellitusWeight Increased
Weight IncreasedDepression
Suicidal IdeationDrug Ineffective
Type 2 Diabetes MellitusSuicidal Ideation
DiarrhoeaBlood Cholesterol Increased

Drug effectiveness by age :

Bupropion Hydrochloride is effectiven/an/a0.00%
(0 of 2 people)
(14 of 41 people)
(7 of 75 people)
(17 of 53 people)
(4 of 25 people)
(3 of 10 people)
Lithium Carbonate is effectiven/an/a0.00%
(0 of 2 people)
(21 of 45 people)
(13 of 62 people)
(16 of 56 people)
(7 of 20 people)
(3 of 6 people)

Most common drug interactions by age * :

Type 2 Diabetes MellitusHormone Level Nos AbnormalSuicidal IdeationDiabetes MellitusType 2 Diabetes MellitusDiabetes MellitusType 2 Diabetes MellitusTremor
Suicide AttemptBipolar I DisorderAgitationDepressionDiabetes MellitusNauseaDiabetes MellitusDepression
HypotensionFeeling AbnormalTremorNauseaDepressionInsomniaDiabetes Mellitus
Diabetic ComplicationSuicide AttemptPyrexiaBlood Cholesterol IncreasedType 2 Diabetes MellitusWeight IncreasedNausea
HyponatraemiaDepressionInsomniaDiabetic KetoacidosisWeight IncreasedTremorAnxiety
Nervous System DisorderOverdoseDizzinessObesityFatiguePainDrug Ineffective
DyspnoeaPersonality DisorderHyperglycaemiaHyperglycaemiaAnxietyAnxietySuicidal Ideation
Pancreatitis AcuteSelf MutilationWeight IncreasedNeuroleptic Malignant SyndromeSuicidal IdeationNeuropathy PeripheralDeath
TremorImpulsive BehaviourGastrooesophageal Reflux DiseaseFatigueBlood Cholesterol IncreasedDepressionMetabolic Encephalopathy
Renal ImpairmentMood SwingsVomitingWeight IncreasedMemory ImpairmentChest PainVomiting

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Bupropion and Lithium Carbonate?

Get connected! Join a mobile support group:
- group for people who take Bupropion and Lithium Carbonate
- group for people who take Bupropion Hydrochloride
- group for people who take Lithium Carbonate

Comments from related studies:

  • From this study (1 week ago):

  • Kevin Peters Ph.d on Mar, 4, 2013:

    Sammy, I'm a white 45 male; just wanted to agree on that Klonopin remark. When I was 21 I had my second kidney transplant which was a BAD issue all together, at any rate the hospital did not include my medications taken at home after my surgery. I went thru the worst hallucinations and jerking and seizures you could ever possibly imagine. This went on for almost 3 1/2 weeks before we decided to have me taken OUT of the hospital and relocated before they ended up taking my life. Then the whole staff of paychology including the chief of psychiatry cane in my room to see what they could do, Finallu. During one of my few moments of clarity the C.O.F after blaming me if talking "drugs" prior to my transplant listened to my word of telling him the meds I was on before being admitted. After asking when was the last time I had received my Klonopin and me not knowing, he then reviewed the charts, and didn't see me receiving this med once. He stormed out of the room of about 9 docs and came back in with two Klonopin; for the first time in almost 4 weeks and after three surgeries the first 72 hours I was hospitalized, I was sleeping like a baby, for about 49 hours with NO MORE hallucinations, or seizures or jerking! I finally got out of there without a kidney since that kidney was supposed to go to another man named the same as I in a different city! I do take Xanax and probably always will. The half life on Klonopin is much different hence one if its dangers, Nevwr Ever stop this drug cold! I've been on dialysis 25 1/2 years now and suffered from intense skin cancers, but have fought and done all I can do to live a normal as possible life, working full time except when I'm in yet another surgery, over 32 general anesthetic procedures since 1987. I was the youngest boy-man to ever be on the USA soccer team ready to play in the Korea 1988 Olympics. What a change in life.....
    All the Best,
    K. Peters


    chris on Jun, 4, 2011:

    i have been taking clonzepam and trazedone and my speech is a very hoarse voice, I am wondering if if my speech problem is from these drugs's side effects.


    TwoDimes on Apr, 15, 2012:

    Upon occasion, I, too, have become hoarse and from the use of Klonopin. I was VERY hoarse when I tried to cold turkey off of 4mgs of Klonopin. I am now down to 1.5mgs per day and, still, (as I said, upon occasion, I become hoarse. I am sure that the use of Klonopin is the causative factor. - TwoDimes -


    SammySushi on Jul, 10, 2012:

    Omigosh, never cold turkey clonopin, esp that high of a dose. My dad had a major seizure and hallucinations doing so.


    Christophe on Nov, 13, 2012:

    I suffer from Hypothyroidism, High Cholesterol & Cancer survivor because of Zyprexa use and previously being prescribed Carbamezapine causing Thyroid damage. My best advice to you if you don't want Hypothyroidism is have regular blood tests, Thyroid damage can be undetected for up to 5 years with no symptoms found on regular blood tests prematurally. Make sure you buy iodised salt to use on food when eating this will help reduce your risk of getting Hypothyroidism. two signs of Hypothyriodism which the Carbamezapine & Zyprexa medication boxes labels wont tell you is if your face becomes puffed up, red or sun sensitive while taking these medications this is a sign of Hypothyroidism. It wont be found on your blood test but later on it could appear out of the blue. The other sign to look for is baldness or hair loss on your head, this is another symptom. I hope these comments will help you. You have to weight up the benefits and negatives taking medications if you decide to take these medicines or not. It depends on how you cope with the drug side effects.
    from Christophe


    AUDREY on Dec, 16, 2012:



    Sonya on Feb, 24, 2013:

    You definately need to take a stool softener...straining during defication can cause major problems in people with cardiac problems.


    Stillaguamish on Sep, 6, 2014:

    My heart breaks for you and I'm so sorry you had to go through all that. I recently had two surgeries and was outraged at hospital treatment. I had to demand my regular meds and when they gave in, they only gave me 3 of 6


  • From this study (4 months ago):

  • Trying to determine if being off of Effexor xr for a month is contributing to chronic fatigue


  • From this study (7 months ago):

  • Stoping topamax. Have not started Lithium yet.


Post a new comment    OR    Read more comments

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More reviews for: Bupropion Hydrochloride, Lithium Carbonate

Complete drug side effects:

On eHealthMe, Bupropion Hydrochloride (bupropion hydrochloride) is often used to treat depression. Lithium Carbonate (lithium carbonate) is often used to treat bipolar disorder. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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