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Review: Clonazepam and Restoril

This review analyzes the effectiveness and drug interactions between Clonazepam and Restoril. It is created by eHealthMe based on reports of 1,538 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: join a mobile support group for people who take Clonazepam and Restoril >>>

What are the drugs

Clonazepam (what 41,200 Clonazepam users reported?) has active ingredients of clonazepam. It is used in stress and anxiety.

Restoril (what 7,634 Restoril users reported?) has active ingredients of temazepam. It is used in insomnia.

On Aug, 18, 2014: 1,538 people who take Clonazepam, Restoril are studied

Clonazepam, Restoril outcomes

Drug combinations in study:
- Clonazepam (clonazepam)
- Restoril (temazepam)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Clonazepam is effective50.00%
(2 of 4 people)
(4 of 12 people)
(3 of 5 people)
(1 of 5 people)
(7 of 14 people)
(3 of 7 people)
(4 of 5 people)
Restoril is effective16.67%
(1 of 6 people)
(4 of 13 people)
(1 of 2 people)
(6 of 8 people)
(3 of 11 people)
(3 of 9 people)
(1 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
ConstipationAnxietyInsomniaCardiac DisorderSuicide AttemptAnxietyNauseaAnxiety
Hepatocellular DamageDepressionNight SweatsBlood Cholesterol IncreasedIntentional OverdosePneumoniaSacral PainPain
DiarrhoeaInsomniaPain In ExtremityGait DisturbanceRashSinus TachycardiaNeuropathyDepression
DyspepsiaNightmarePalpitationsDecubitus UlcerDyspnoeaSickle Cell Anaemia With CrisisLumbosacral Root PainDiabetes Mellitus
NightmareEmotional DisorderNauseaCoordination AbnormalOsteoporosisAbdominal Wall HaematomaAnterior Knee PainFall
RashDisturbance In AttentionMalaiseComaBack InjuryDilatation VentricularAnxietyBack Pain
HeadacheIrritabilityImpaired Driving AbilityConfusional StateArterial Thrombosis LimbHaemoglobin DecreasedSleeplessnessDizziness
Abdominal DistensionNeuropathy PeripheralImpaired Work AbilitySeptic ShockPulmonary HypertensionFrequent Bowel MovementsTesticular PainChest Pain
Urinary RetentionWeight DecreasedPanic AttackSpeech DisorderSpinal DeformityTibia FracturePainDyspnoea
HypoaesthesiaType 2 Diabetes MellitusMorbid ThoughtsUrinary Tract InfectionAcneOxygen Saturation DecreasedPain In LimbType 2 Diabetes Mellitus

Drug effectiveness by gender :

Clonazepam is effective35.71%
(10 of 28 people)
(14 of 24 people)
Restoril is effective30.77%
(8 of 26 people)
(11 of 24 people)

Most common drug interactions by gender * :

PainNeuropathy Peripheral
DizzinessBack Pain
Diabetes MellitusDiabetes Mellitus
InsomniaType 2 Diabetes Mellitus
Chest PainDyspnoea

Drug effectiveness by age :

Clonazepam is effective0.00%
(0 of 1 people)
(2 of 15 people)
(8 of 58 people)
(7 of 16 people)
(6 of 18 people)
(1 of 13 people)
Restoril is effective0.00%
(0 of 1 people)
(2 of 15 people)
(6 of 44 people)
(8 of 16 people)
(3 of 17 people)
(0 of 13 people)

Most common drug interactions by age * :

Cryingn/aAccidental DeathRespiratory DepressionDiabetes MellitusDepressionAnxietyAnxiety
Multiple Drug OverdoseDrug AbuseType 2 Diabetes MellitusAnxietyPainArthralgia
Foaming At MouthDyspnoeaNauseaType 2 Diabetes MellitusFallPain
Cardiac ArrestSuicidal IdeationAnxietyPainInsomniaFall
DepressionMood SwingsBack PainDiabetes MellitusDepressionDizziness
ScarJoint SprainSuicidal IdeationChest PainAbdominal PainInjury
Female Sexual DysfunctionVaginal DischargeDiabetic NeuropathyDyspnoeaDiabetes MellitusPain In Extremity
Chest DiscomfortCompleted SuicideFatigueDizzinessChest Pain
Muscle SpasmsHeadachePneumoniaBack PainDiarrhoea
AstheniaPain In ExtremityNauseaHeadacheBack Pain

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group:
- group for people who take Clonazepam and Restoril
- group for people who take Clonazepam
- group for people who take Restoril

Comments from related studies:

  • From this study (2 months ago):

  • Two hour episode of the sensation of bugs crawling all on my body, on different spots at different times.


  • From this study (3 months ago):

  • Been on MS ContinSR 100mg, Tizanadine(Zanaflex) 4mg for 10+years and it does not much at all to help, also MS Contin 15mgIR in between. Pain is severe, fatigue is extreme, lack of sleep is hardest. Just started Temazepam for sleep,insurance co's. wants huge co pay for Ambien so had to go with something old for sleeep. Savella, just started idea yet if it's going to help.
    Due to fatigue, lack of sleep, extreme bone and muscle pain bones have turned in degenerative disc disease. Exercise is what is impossible to do due to pain,lack of sleep.


    Linda on Jun, 9, 2014:

    Female, age 52, Fibro and Ankylosing Spondylitis. I took Ambien for one or two years. Either a) didn't work at all,
    b) worked too well and I was hung over the next day or
    c) made me walk in my sleep. Once I cleanly the whole house in my sleep, which was a nice surprise the next morning. But once I took a huge butcher knife and hid it under the bed.


  • From this study (8 months ago):

  • I was started on Pristiq yesterday. Given 50 mg. and was told by my Dr. to cut the pill in half and take 25 mg. for 5 days, then start taking the whole pill(50 mg.) I developed Tardive Dykinesia Oct. of 2011. All symptoms did reverse themselves with the exception of short and long term memory impairement. After taking first dose of Pristiq yesterday, I experienced 2 symptoms that I had when I developed Tardive Dyskinesia; abnormal respirations and impaired gait. Could Pristiq trigger Tardive dyskinesia to recur?


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Complete drug side effects:

On eHealthMe, Clonazepam (clonazepam) is often used to treat stress and anxiety. Restoril (temazepam) is often used to treat insomnia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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