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Review: taking Clonidine and Xanax together

Summary: drug interactions are reported among people who take Clonidine and Xanax together.

This review analyzes the effectiveness and drug interactions between Clonidine and Xanax. It is created by eHealthMe based on reports of 797 people who take the same drugs from FDA and social media, and is updated regularly.


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On Mar, 15, 2015: 797 people who take Clonidine Hydrochloride, Xanax are studied

Clonidine Hydrochloride, Xanax outcomes

Drug combinations in study:
- Clonidine Hydrochloride (clonidine hydrochloride)
- Xanax (alprazolam)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Clonidine Hydrochloride is effective20.00%
(1 of 5 people)
(1 of 6 people)
(2 of 3 people)
(1 of 4 people)
(4 of 7 people)
(1 of 1 people)
(2 of 3 people)
Xanax is effective25.00%
(1 of 4 people)
(2 of 2 people)
(1 of 3 people)
(3 of 4 people)
(3 of 7 people)
(3 of 4 people)
(5 of 6 people)

Drug effectiveness by gender :

Clonidine Hydrochloride is effective52.63%
(10 of 19 people)
(2 of 10 people)
Xanax is effective65.00%
(13 of 20 people)
(5 of 10 people)

Drug effectiveness by age :

Clonidine Hydrochloride is effectiven/an/an/a10.00%
(3 of 30 people)
(4 of 15 people)
(0 of 5 people)
(4 of 21 people)
(1 of 5 people)
Xanax is effectiven/an/an/a13.33%
(4 of 30 people)
(4 of 15 people)
(1 of 5 people)
(5 of 21 people)
(4 of 6 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Drug IneffectiveMaternal Exposure During PregnancyDetoxificationDrug IneffectiveExhaustion, Fatigue, Lethargy, Tiredness, WearinessHigh Blood PressureCoronary Artery DiseaseNausea
Median Nerve InjuryAbortion SpontaneousPainDetoxificationInsomnia ExacerbatedNight SweatsCognitive DisorderAnxiety
OsteomyelitisVomitingSyncopeDizzinessVision BlurredJoint StiffnessDeliriumDepression
Drug DependenceSomnolenceCompleted SuicidePainSleepyNausea AggravatedDizzinessDrug Ineffective
Maternal Exposure During PregnancyAbdominal PainDrug IneffectiveCompleted SuicideSweating - ExcessiveDizziness PosturalDysuriaDrug Withdrawal Syndrome
PainNephrogenic Systemic FibrosisParaesthesiaSyncopeDrowsinessDementiaCarotid Artery StenosisDrug Dependence
DepressionGranulomaDrug DependenceParaesthesiaMucosal Dryness NosDrug DependenceAtrioventricular BlockPain
Gun Shot WoundMuscle TwitchingDizzinessDrug DependenceDry MouthDyspnoeaDelusional Disorder, Paranoid TypeHeadache
SurgerySkin ReactionBradycardiaNephrolithiasisDementiaPanic AttackMental Status ChangesAsthenia
Radius FractureSeizure ClusterDeathRashBack PainDrug AbuserBlue VisionChest Pain

Most common drug interactions by gender * :

Drug IneffectiveDrug Withdrawal Syndrome
AnxietyDrug Dependence
DepressionDrug Ineffective
AstheniaOedema Peripheral
Drug Withdrawal SyndromeHeadache
Drug DependenceDehydration
Chest PainDyspnoea

Most common drug interactions by age * :

Neonatal DisorderAutismOverdose NosDrug Withdrawal SyndromeDrug DependenceChest PainAnxietyAsthenia
Metabolic AcidosisAnaphylactic ReactionPalpitationsNauseaDrug Withdrawal SyndromeNauseaDepressionDrug Ineffective
Neonatal HypotensionAggressionSweating IncreasedWeight DecreasedAnxietyDepressionDrug Withdrawal SyndromeDyspnoea
Oxygen Saturation DecreasedOverdoseVomiting NosDrug DependenceDepressionHeadacheNauseaWeakness
Ventricular FibrillationComaNauseaAnxietyNauseaAnxietyDrug DependenceNausea
Premature BabyHepatic FailureHeadacheFormicationDysarthriaDrug Withdrawal SyndromeOedema PeripheralTremor
Maternal Condition Affecting FoetusBrain DamageConvulsionDyskinesiaArthralgiaAstheniaArthralgiaBlood Pressure Increased
MalaiseUnresponsive To StimuliMuscle SpasmsHypertensionDizzinessDrug IneffectiveBlood Glucose Increased
Bradycardia NeonatalElectrocardiogram Qt ProlongedDrug AbuserPainSinus TachycardiaPyrexiaAnxiety
Congenital Tricuspid Valve AtresiaFeeling AbnormalPainDysuriaDehydrationBursitisOedema Peripheral

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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- support group for people who take Clonidine Hydrochloride
- support group for people who take Xanax

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Clonidine Hydrochloride (clonidine hydrochloride) is often used to treat high blood pressure. Xanax (alprazolam) is often used to treat stress and anxiety. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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