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Review: Crestor and Cymbalta





Summary: drug interactions are reported among people who take Crestor and Cymbalta together.

This review analyzes the effectiveness and drug interactions between Crestor and Cymbalta. It is created by eHealthMe based on reports of 1,044 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Crestor and Cymbalta >>>

What are the drugs

Crestor has active ingredients of rosuvastatin calcium. It is often used in hyperlipidaemia. (latest outcomes from Crestor 60,035 users)

Cymbalta has active ingredients of duloxetine hydrochloride. It is often used in depression. (latest outcomes from Cymbalta 49,275 users)

On Dec, 2, 2014: 1,044 people who take Crestor, Cymbalta are studied

Crestor, Cymbalta outcomes

Drug combinations in study:
- Crestor (rosuvastatin calcium)
- Cymbalta (duloxetine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Crestor is effective0.00%
(0 of 1 people)
50.00%
(4 of 8 people)
46.15%
(6 of 13 people)
50.00%
(7 of 14 people)
53.12%
(17 of 32 people)
91.67%
(11 of 12 people)
66.67%
(2 of 3 people)
n/a
Cymbalta is effective50.00%
(1 of 2 people)
16.67%
(3 of 18 people)
33.33%
(2 of 6 people)
5.56%
(1 of 18 people)
41.94%
(13 of 31 people)
50.00%
(6 of 12 people)
50.00%
(2 of 4 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DeliriumDeliriumMuscular WeaknessDepressionMemory ImpairmentDiarrheaDysphoniaPain
InsomniaInsomniaHepatic FailureSomnolenceMyocardial InfarctionHypersomniaRashNausea
DepressionConstipationDry MouthDisturbance In AttentionCryingAttention Deficit/hyperactivity DisorderCarpal Tunnel SyndromeDizziness
AgitationWeight DecreasedChest Tightness Or PressureTremorFeeling AbnormalPulmonary HypertensionTension HeadacheHeadache
HeadacheHallucinationFatigueInsomniaVomitingRadiation InteractionFatiguePain In Extremity
NauseaOedema PeripheralGastrooesophageal Reflux DiseaseFatigueOedema PeripheralApathyJoint PainFatigue
Weight DecreasedAstheniaDiarrheaMental Status ChangesTinnitusFatigue - ChronicDepressionAnxiety
TremorDeafnessMuscle Contractions InvoluntaryLoss Of ConsciousnessRashBack PainHeart FibrillationDyspnoea
AnxietyPain In ExtremityAmyotrophic Lateral SclerosisLethargyTremorDepressionHeart Rate IncreasedInsomnia
FatigueMyalgiaOedema PeripheralConfusional StateNauseaFibromyalgiaParanoiaDepression

Drug effectiveness by gender :

FemaleMale
Crestor is effective55.17%
(32 of 58 people)
60.00%
(15 of 25 people)
Cymbalta is effective32.81%
(21 of 64 people)
25.93%
(7 of 27 people)

Most common drug interactions by gender * :

FemaleMale
NauseaDyspnoea
PainDrug Ineffective
AnxietyHeadache
FallArthralgia
AstheniaSomnolence
DepressionAnxiety
DizzinessFatigue
Pain In ExtremitySuicidal Ideation
Oedema PeripheralBlood Glucose Increased
FatiguePain

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Crestor is effectiven/an/an/an/a75.00%
(3 of 4 people)
12.50%
(7 of 56 people)
28.05%
(23 of 82 people)
45.16%
(14 of 31 people)
Cymbalta is effectiven/an/an/a0.00%
(0 of 5 people)
25.00%
(1 of 4 people)
6.56%
(4 of 61 people)
13.54%
(13 of 96 people)
31.25%
(10 of 32 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Type 2 Diabetes Mellitusn/aDecreased InterestInfusion Related ReactionWeight IncreasedPainNauseaNausea
Sensation Of Foreign BodyBalance DisorderType 2 Diabetes MellitusDiabetes MellitusDyspnoeaInsomniaFall
PolydactylyDepressionMitral Valve IncompetenceType 2 Diabetes MellitusAnxietyDrug IneffectiveAsthenia
Premature BabyTremorStress CardiomyopathyCholelithiasisHeadachePainDizziness
Anomaly Of External Ear CongenitalHyperhidrosisDiabetes MellitusIntervertebral Disc ProtrusionArthralgiaWeight DecreasedAnxiety
Gallbladder OperationSensory DisturbanceVaginal FistulaNeuropathy PeripheralNauseaFatiguePain
Blood Cholesterol IncreasedLoss Of ConsciousnessParathyroid DisorderGallbladder DisorderWeight IncreasedArthralgiaVomiting
Musculoskeletal PainAstheniaCondition AggravatedSpinal DisorderDizzinessDiarrhoeaFatigue
Musculoskeletal DisorderDysphoriaRenal Failure ChronicDepressionRashVomitingDyspnoea
Myoglobin Blood IncreasedSchizophreniaChest PainMyocardial InfarctionFatigueFeeling AbnormalHeadache

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Crestor and Cymbalta?

You are not alone! Join a related mobile support group:
- support group for people who take Crestor and Cymbalta
- support group for people who take Crestor
- support group for people who take Cymbalta

Recent conversations of related support groups:

  • Support group for people who take Cymbalta
    Now found out I have incompetent vein in leg which may be part of the problem had cystocopy and found cysts in kidney, then developed hypertension but no one will diagnose the pain. Now decided it is the same as diabetic neuropathy but as gp and consultant point out I am a long way from being diabetic with perfect blood glucose so thinks it's just guessing and hope

Can you answer these questions (Ask a question):

More questions for: Crestor, Cymbalta

You may be interested at these reviews (Write a review):

  • Cymbalta side effects
    Starting Cymbalta, side effects were dizzy,felt drugged. Helped with Arthritis pain. About six weeks after i started i developed rectal bleeding.Doctor had me stop Cymbalta and use Tramadol as needed for withdrawal.
  • Cardio version caused fingernail abnormalities
    Right hip fracture. When prepping for surgery AFIB was found. Surgery was cancelled and they attempted to get AFIB under control. Finally, cardioversion was performed. When my nails started to grow out they all had two horizontal lines that cause the nail to break when it grows out to that point.
  • Numbness between toes
    This summer I flip flops, with the strap between my toes, almost exclusively. When I switched this fall to regular shoes I noticed a strange, numb sensation between my big toe and second toe. At first I thought it had something to do with the flip flops and thought it would go away. It has been a few weeks now and this has not gone away, and if anything seems to cover a larger area. Oddly enough I mentioned this to a friend today and she says she has the same thing, between her second and third toe...both of us on our right feet. She is also on an antidepressant but couldn't remember which one, but we thought this was an odd coincidence. She explained it as sort of a sensation that there is a hole in your sock or shoe...and that made sense to me...there is still some sensation in the area but it is an odd feeling...something isn't quite right. I am doing some online research right now to try to figure out if this is common with Cymbalta or not?
  • Cymbalta caused joint pain
    I had taken Cymbalta for about 1.5 years and after taking it for a few months, I started having widespread joint pain. The joint pain has gotten worse and is becoming debilitating. Joint pain in the literature as a side affect of the drug but the joint pain seems to be permanent! I have not taken Cymbalta in a couple years but the joint pain has remained. I have had blood tests and my doctor says the tests show it is not arthritis.
  • Transition from mirtazapine to cymbalta (bipolar ii) 6 week duration taken in conjunction with seroquel, propranalol and implanon
    In early September I approached my Psychiatrist to report that I was having sleep paralysis episodes as well as insatiable appetite. I had put on about 20lb in the space of 6 months since the sleep paralysis started.

    My Psychiatrist opted to wean me off the Mirtazapine and onto Cymbalta. I have now been on 60mg of Cymbalta for about 4 weeks and completely titrated off the Mirtazapine.

    I have noted that since switching to Cymbalta that I no longer have the insatiable appetite, nor have I had any further sleep paralysis episodes (though I have had a brain MRI to rule out any physiological issues - yet to receive results).

    I have noticed that I have had mild to moderate rolling nausea with the Cymbalta and that I now have food aversions. Food does not interest me as much anymore and I find that certain foods (mostly processed snacks) are no longer palatable. I also find that I become full after much smaller meal portions.

    I have found that I can no longer drink wine or spirits because they now taste awful however I can still tolerate certain brands of beer. I also no longer enjoy drinking cola.

    I am also on the Implanon Implant. I have had this implant inserted for about 12 months and my cycles have been rather regular. Since starting the Cymbalta I have had some breakthrough bleeding yet my periods have not been as painful, though they have been heavier and longer.

    My Psychiatrist will commence titrating me off the Seroquel in about two weeks and onto Topamax as it is his belief it will be less sedating than the Seroquel and that it will hopefully help as a mood stabiliser, treat my migraines and allow me to come off the Propranolol. he also hopes that I am able to loose some of the weight gained since the sleep paralysis episodes started.

    As a side note regarding the Propranolol, I have naturally low blood pressure and I find while Propranalol is generally an effective migraine prophylactic, (I do get some breakthrough migraines) it does make my blood pressure even lower which leads to dizziness and faintness when I stand up too quickly from a recumbent position.

More reviews for: Crestor, Cymbalta

Comments from related studies:

  • From this study (5 months ago):

  • Occurs summer & winter. Is somewhat debilitating.

    Reply

  • From this study (7 months ago):

  • Have had unidentified autoimmune disease for five years, elevated cardiac enzymes from coronary vasospasms, joint pain, arthritis, muscle weakness, muscle tears

    Reply

  • From this study (9 months ago):

  • Over past 6+ years, hair has thinned by half.

    Reply

    help on Apr, 9, 2014:

    hair loss maybe due to thyroid issues?

    Reply

Post a new comment    OR    Read more comments

Complete drug side effects:

On eHealthMe, Crestor (rosuvastatin calcium) is often used to treat high blood cholesterol. Cymbalta (duloxetine hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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