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Review: taking Crestor and Cymbalta together

Summary: drug interactions are reported among people who take Crestor and Cymbalta together.

This review analyzes the effectiveness and drug interactions between Crestor and Cymbalta. It is created by eHealthMe based on reports of 1,047 people who take the same drugs from FDA and social media, and is updated regularly.


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On Apr, 8, 2015: 1,047 people who take Crestor, Cymbalta are studied

Crestor, Cymbalta outcomes

Drug combinations in study:
- Crestor (rosuvastatin calcium)
- Cymbalta (duloxetine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Crestor is effective0.00%
(0 of 1 people)
(4 of 8 people)
(6 of 13 people)
(7 of 14 people)
(18 of 34 people)
(11 of 12 people)
(3 of 4 people)
Cymbalta is effective50.00%
(1 of 2 people)
(3 of 18 people)
(2 of 6 people)
(1 of 20 people)
(13 of 31 people)
(7 of 13 people)
(2 of 4 people)

Drug effectiveness by gender :

Crestor is effective55.74%
(34 of 61 people)
(15 of 25 people)
Cymbalta is effective32.84%
(22 of 67 people)
(7 of 27 people)

Drug effectiveness by age :

Crestor is effectiven/an/an/an/a75.00%
(3 of 4 people)
(7 of 56 people)
(24 of 87 people)
(15 of 35 people)
Cymbalta is effectiven/an/an/a0.00%
(0 of 5 people)
(1 of 4 people)
(4 of 61 people)
(14 of 101 people)
(10 of 36 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DeliriumDeliriumMuscular WeaknessTremorMemory ImpairmentDiarrheaDroolingPain
InsomniaInsomniaHepatic FailureMental Status ChangesMyocardial InfarctionFatigue - ChronicIncontinenceNausea
DepressionConstipationDry MouthDisturbance In AttentionCryingNeuropathy PeripheralDysphoniaDizziness
AgitationWeight DecreasedChest Tightness Or PressureDepressionFeeling AbnormalApathyRashHeadache
HeadacheHallucinationFatigueFatigueCerebrovascular AccidentAttention Deficit/hyperactivity DisorderTension HeadachePain In Extremity
NauseaOedema PeripheralGastrooesophageal Reflux DiseaseInsomniaBlood Triglycerides IncreasedPulmonary HypertensionCarpal Tunnel SyndromeFatigue
Weight DecreasedAstheniaDiarrheaSomnolenceNeuropathy PeripheralHypersomniaLack Of Strength, Muscle Weakness, WeaknessAnxiety
TremorDeafnessMuscle Contractions InvoluntaryUnresponsive To StimuliGait DisturbanceLoss Of HairChronic DepressionDyspnoea
AnxietyPain In ExtremityAmyotrophic Lateral SclerosisDeliriumOedema PeripheralBack PainHeart FibrillationInsomnia
FatigueMyalgiaOedema PeripheralParanoiaAnxietyLack Of Strength, Muscle Weakness, WeaknessDepressionDepression

Most common drug interactions by gender * :

PainDrug Ineffective
Pain In ExtremityFatigue
DizzinessSuicidal Ideation
Oedema PeripheralBlood Glucose Increased

Most common drug interactions by age * :

Type 2 Diabetes Mellitusn/aDecreased InterestInfusion Related ReactionWeight IncreasedPainNauseaNausea
Sensation Of Foreign BodyBalance DisorderType 2 Diabetes MellitusDiabetes MellitusDyspnoeaInsomniaFall
PolydactylyDepressionMitral Valve IncompetenceType 2 Diabetes MellitusAnxietyDrug IneffectiveAsthenia
Premature BabyTremorStress CardiomyopathyCholelithiasisHeadachePainAnxiety
Anomaly Of External Ear CongenitalHyperhidrosisDiabetes MellitusIntervertebral Disc ProtrusionArthralgiaWeight DecreasedDizziness
Gallbladder OperationSensory DisturbanceVaginal FistulaNeuropathy PeripheralNauseaArthralgiaPain
Blood Cholesterol IncreasedLoss Of ConsciousnessParathyroid DisorderGallbladder DisorderWeight IncreasedFatigueHeadache
Musculoskeletal PainAstheniaCondition AggravatedSpinal DisorderDizzinessDiarrhoeaDyspnoea
Musculoskeletal DisorderDysphoriaRenal Failure ChronicDepressionRashDizzinessVomiting
Myoglobin Blood IncreasedSchizophreniaChest PainMyocardial InfarctionFatigueSuicidal IdeationFatigue

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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- support group for people who take Crestor
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Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Crestor (rosuvastatin calcium) is often used to treat high blood cholesterol. Cymbalta (duloxetine hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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