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Review: taking Cymbalta and B Complex Vitamin together

Summary: drug interactions are reported among people who take Cymbalta and B Complex Vitamin together.

This review analyzes the effectiveness and drug interactions between Cymbalta and B Complex Vitamin. It is created by eHealthMe based on reports of 1,411 people who take the same drugs from FDA and social media, and is updated regularly.


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On Mar, 3, 2015: 1,411 people who take Cymbalta, B Complex Vitamin are studied

Cymbalta, B Complex Vitamin outcomes

Drug combinations in study:
- Cymbalta (duloxetine hydrochloride)
- B Complex Vitamin (folic acid)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Cymbalta is effective0.00%
(0 of 3 people)
(2 of 5 people)
(4 of 9 people)
(7 of 16 people)
(11 of 19 people)
(1 of 2 people)
(0 of 1 people)
B Complex Vitamin is effective0.00%
(0 of 5 people)
(3 of 8 people)
(2 of 3 people)
(2 of 11 people)
(5 of 8 people)
(6 of 7 people)
(2 of 2 people)

Drug effectiveness by gender :

Cymbalta is effective47.83%
(22 of 46 people)
(3 of 8 people)
B Complex Vitamin is effective47.22%
(17 of 36 people)
(3 of 8 people)

Drug effectiveness by age :

Cymbalta is effectiven/an/an/a50.00%
(3 of 6 people)
(5 of 19 people)
(7 of 36 people)
(9 of 43 people)
(1 of 11 people)
B Complex Vitamin is effectiven/an/an/a50.00%
(2 of 4 people)
(3 of 18 people)
(6 of 33 people)
(8 of 37 people)
(1 of 10 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
PyrexiaWeight DecreasedDrug Exposure During PregnancyCataractHepatic FailureSuicidal IdeationHeart Rate IncreasedPain
NauseaDrug IneffectiveSmall For Dates BabyFibromyalgiaDiarrheaShaking PalsyNauseaNausea
Renal FailureHepatitisPremature BabyJoint SwellingMuscle WeaknessSweating - ExcessiveWeaknessFatigue
Ocular IcterusJaundice CholestaticApnoeaImmune System DisorderLower Blood PressureStomach PainFatigueFall
Memory ImpairmentPancreatitis ChronicBradycardia NeonatalPainSinus HeadacheMuscle TwitchingHeadachePain In Extremity
DepressionHypotensionPulmonary Valve StenosisArthralgiaBone And Joint PainVertigo PositionalArthralgia
Fibrin D Dimer IncreasedConfusional StateOcular IcterusMyocardial InfarctionMalabsorptionAmenorrhea - SecondaryDyspnoea
DelusionBlood Glucose DecreasedHypotensionOedema PeripheralAnxietyTooth AbscessHeadache
Blood Glucose IncreasedRenal CystYellow SkinHerpes ZosterHigh Blood CholesterolMuscle WeaknessDiarrhoea
Haematocrit DecreasedHepatic CystHyperhidrosisDrug IneffectiveFatigue - ChronicLightheadednessDepression

Most common drug interactions by gender * :

FallRenal Failure Acute
Pain In ExtremityWeight Decreased

Most common drug interactions by age * :

n/aPremature BabyType 2 Diabetes MellitusNauseaFatiguePainNauseaPain
Low Birth Weight BabyDiabetes MellitusBiliary DyskinesiaPainConstipationPainFatigue
Foetal Exposure During PregnancyRheumatoid ArthritisPain In ExtremityPain In ExtremityNauseaFatigueAnaemia
GastritisCholecystitis ChronicDepressionAnxietyHeadacheFall
Gallbladder DisorderAbdominal Pain UpperHeadacheRenal Failure AcuteDepressionNausea
Cholecystitis ChronicDepressionArthralgiaDrug IneffectiveArthralgiaCardiac Failure Congestive
Drug Withdrawal ConvulsionsDrug Exposure During PregnancyPyrexiaOedema PeripheralInsomniaDyspnoea
Nail DisorderHypokalaemiaStaphylococcal InfectionFatigueFallNeuropathy Peripheral
Injection Site SwellingAbdominal PainNephrolithiasisFallPain In ExtremityAsthenia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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- support group for people who take B Complex Vitamin
- support group for people who take Cymbalta

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Cymbalta (duloxetine hydrochloride) is often used to treat depression. B Complex Vitamin (folic acid) is often used to treat energy increased. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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