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Review: Cymbalta and Gabapentin and Tryptophan

This review analyzes the effectiveness and drug interactions between Cymbalta and Gabapentin and Tryptophan. It is created by eHealthMe based on 4,325 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Apr, 2, 2014: 4,325 people who reported to have interactions when taking Cymbalta, Gabapentin, Tryptophan are studied

Trend of Cymbalta, Gabapentin, Tryptophan's drug interactions, side effects and effectiveness reports (3329415)

Drug combinations in study:
- Cymbalta (duloxetine hydrochloride)
- Gabapentin (gabapentin)
- Tryptophan (l - tryptophan)

eHealthMe real world results:

Most common interactions experienced by people in the use of Cymbalta, Gabapentin, Tryptophan:

InteractionNumber of reports
Pain1,992
Anxiety1,955
Nausea (feeling of having an urge to vomit)1,491
Dyspnoea (difficult or laboured respiration)1,483
Fatigue (feeling of tiredness)1,337
Depression1,194
Dizziness1,150
Fall1,128
Headache (pain in head)1,127
Back Pain998

Most common interactions experienced by people in long term use of Cymbalta, Gabapentin, Tryptophan:

InteractionNumber of reports
Anxiety138
Pain117
Vomiting112
Depression90
Suicidal Ideation74
Pancreatitis (inflammation of pancreas)74
Headache (pain in head)70
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)66
Insomnia (sleeplessness)65
Weight Decreased64

How effective are the drugs:

not at allsomewhatmoderatehighvery high
Cymbalta4.76%36.51%33.33%17.46%7.94%
Gabapentin4.69%25.00%45.31%15.62%9.38%
Tryptophan0.000.000.000.000.00

Top conditions involved for these people * :

  1. Depression
  2. Pain
  3. Anxiety
  4. Hypertension
  5. Multiple sclerosis

Top co-used drugs for these people * :

  1. Neurontin
  2. Seroquel
  3. Lyrica
  4. Aspirin
  5. Xanax

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Complete drug side effects:

Comments from related studies:

  • From this study (3 days ago):

  • Have gained about 70lbs. In a year, cant lose weight. Every symptom of hypothyroidism and/or adrenal fatigue. I am 34yrs. Old with 3 kids, I weigh about 190lbs, which I only weigh this much when pregnant.
    please help

    Reply

  • From this study (1 month ago):

  • Have been on Gabapentin for years now. For the past 3-4 yrs, I have had a chronically elevated WBC without evidence of illness. WBCs run 10.5 to 13.0 consistently. Even when on antibiotics, has not dropped below 10.5. Am now wondering if this could be related to Gabapentin. The elevated WBCs have resulted in delay of care for back pain issues. At one time, I tried to get off of gabapentin - was titrating the dose(c my provider's permission). I noticed that the Restless Leg Syndrome that I had been experiencing had disappeared with the lower dose of Gabapentin. Unfortunately, the Meralgia Paresthetica synotoms increased & had to increase the Gabapentin back up. RLS came back with increased dose.

    Reply

  • From this study (1 month ago):

  • Have been on Gabapentin for years now. For the past 3-4 yrs, I have had a chronically elevated WBC without evidence of illness.WBCs run 10.5 tp 13.0 consistanly. Even when on antibiotics, has not dropped below 10.5. Am now wondering if this could be related to Gabapentin. The elevated WBCs have resulted in delay of care for back pain issues. At one time, I tried to get off of gabapentin - was titrating the dose(c my provider's permission). I noticed that the Restless Leg Syndrome that I had been experiencing had disappeared with the lower dose of Gabapentin. Unfortunately, the Meralgia Paresthetica synotoms increase & had to increase the Gabapentin back up. RLS came back with increased dose.

    Reply

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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