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Review: Diclofenac and Tylenol





Summary: drug interactions are reported among people who take Diclofenac and Tylenol together.

This review analyzes the effectiveness and drug interactions between Diclofenac and Tylenol. It is created by eHealthMe based on reports of 2,596 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Diclofenac and Tylenol >>>

What are the drugs

Diclofenac sodium has active ingredients of diclofenac sodium. It is often used in arthritis. (latest outcomes from Diclofenac sodium 14,955 users)

Tylenol has active ingredients of acetaminophen. It is often used in pain. (latest outcomes from Tylenol 55,615 users)

On Dec, 18, 2014: 2,596 people who take Diclofenac Sodium, Tylenol are studied

Diclofenac Sodium, Tylenol outcomes

Drug combinations in study:
- Diclofenac Sodium (diclofenac sodium)
- Tylenol (acetaminophen)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Diclofenac Sodium is effective40.00%
(4 of 10 people)
0.00%
(0 of 5 people)
n/a20.00%
(1 of 5 people)
25.00%
(1 of 4 people)
60.00%
(3 of 5 people)
50.00%
(1 of 2 people)
0.00%
(0 of 3 people)
Tylenol is effective20.00%
(2 of 10 people)
50.00%
(2 of 4 people)
0.00%
(0 of 3 people)
0.00%
(0 of 3 people)
25.00%
(1 of 4 people)
50.00%
(1 of 2 people)
33.33%
(2 of 6 people)
50.00%
(1 of 2 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
VomitingNephrotic SyndromeAstheniaPetechiaeVitamin B12 DecreasedConjunctival HaemorrhageNauseaNausea
PyrexiaRenal FailurePetechiaeAplastic AnaemiaPseudomembranous ColitisAcute Hepatic FailureVomitingPain
NauseaPulmonary EmbolismAplastic AnaemiaAstheniaBlood Count AbnormalThrombosisRed Blood Cell Count DecreasedPyrexia
Renal Failure AcuteDeep Vein ThrombosisPyrexiaOedema PeripheralFatigueLiver Function Test AbnormalHaematocrit DecreasedVomiting
DiarrhoeaHaemoglobin DecreasedHypotensionDehydrationTinnitusVomitingAstheniaRenal Failure Acute
Blood Creatinine IncreasedPyrexiaRespiratory FailureArthralgiaHepatomegalyHepatitis AcuteStaphylococcal InfectionDiarrhoea
Haemoglobin DecreasedRetroperitoneal FibrosisPleural EffusionDiarrhoeaCytolytic HepatitisAspartate Aminotransferase IncreasedColitis UlcerativeHeadache
Abdominal PainConvulsionMulti-organ FailureUrinary Tract InfectionCholestasisAlanine Aminotransferase IncreasedRectal HaemorrhageArthralgia
AnaemiaMetastases To LiverRhabdomyolysisSwelling FaceGastrointestinal HaemorrhageBlood Albumin IncreasedPallorDyspnoea
MalaiseRenal Failure AcuteChest PainWeight DecreasedDermatitisPyrexiaDecreased AppetiteDehydration

Drug effectiveness by gender :

FemaleMale
Diclofenac Sodium is effective25.93%
(7 of 27 people)
42.86%
(3 of 7 people)
Tylenol is effective26.92%
(7 of 26 people)
25.00%
(2 of 8 people)

Most common drug interactions by gender * :

FemaleMale
NauseaPyrexia
PainRenal Failure Acute
VomitingDyspnoea
PyrexiaVomiting
DiarrhoeaNausea
HeadacheAnaemia
ArthralgiaDiarrhoea
DehydrationHypotension
FatigueArthralgia
Renal Failure AcutePain

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Diclofenac Sodium is effectiven/an/a0.00%
(0 of 3 people)
0.00%
(0 of 3 people)
0.00%
(0 of 2 people)
0.00%
(0 of 19 people)
40.00%
(4 of 10 people)
33.33%
(6 of 18 people)
Tylenol is effectiven/an/a0.00%
(0 of 3 people)
33.33%
(1 of 3 people)
0.00%
(0 of 2 people)
5.26%
(1 of 19 people)
22.22%
(2 of 9 people)
27.78%
(5 of 18 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Placental InsufficiencyDiarrhoeaVomitingVomitingPyrexiaNauseaHeadacheRenal Failure Acute
DeathAccidental Drug Intake By ChildNauseaNauseaArthralgiaPyrexiaPyrexiaDehydration
Viral Infection NosRenal Tubular NecrosisMalaiseAbdominal PainDiarrhoeaDyspnoeaPainPain
Metabolic AcidosisSkin DiscolourationIntentional OverdosePyrexiaMaternal Exposure During PregnancyFatigueDiarrhoeaNausea
OligohydramniosRenal Failure AcuteSyncopeConvulsionVomitingHeadacheNauseaConfusional State
Renal Failure NeonatalConvulsions NosChest DiscomfortDrug Exposure During PregnancyRenal Failure AcuteAbdominal PainArthralgiaPyrexia
Respiratory Disorder NosCardiac ArrestLoss Of ConsciousnessCondition AggravatedAbdominal PainMuscular WeaknessVomitingRheumatoid Arthritis
PyrexiaChemical InjuryBlood Glucose DecreasedTachycardiaPainMulti-organ FailurePain In ExtremityOsteoarthritis
Vomiting NeonatalEncephalopathy NosDiarrhoeaLoss Of ConsciousnessDyspnoeaArthralgiaAnaemiaDiarrhoea
Neonatal TachypnoeaHeart Rate IncreasedCyanosisDehydrationDepressionChest PainAstheniaHaemoglobin Decreased

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Diclofenac and Tylenol?

You are not alone! Join a related mobile support group:
- support group for people who take Diclofenac and Tylenol
- support group for people who take Diclofenac Sodium
- support group for people who take Tylenol

Can you answer these questions (Ask a question):

More questions for: Diclofenac Sodium, Tylenol

You may be interested at these reviews (Write a review):

  • I need advise, badly ckd!! (1 response)
    The orthostatic BP started in mid April, I was only dizzy upon wakening then it would subside. I have never been a big breakfast eater so I started doing that. We were in Disney later in April and I was extremely fatigued, to the point of not wanting to walk, Disney would be the first time I passed out when getting dizzy. I of course said I had gotten too warm and was exhausted from work the previous week. The dizziness continued in the mornings & I passed out several more times. On May 1st, I passed out while putting my make-up on and hit my eye on the faucet and head on the tile floor, despite that I went to work thinking it would subside, it didn't. I went to the ER directly after work. They ran a B-met on me and my GFR was 11 and creatinine 3.95. They admitted me to a larger hospital for evaluation. While in there, they pumped me with fluids continuously, saying I had severe dehydration. My kidney function improved, my creatinine levels went back down to 1.34. After 5 days I was discharged and told to see a cardiologist and endo. The endo doc cancelled my appointment on the basis it was not his area. I had had a cortisol and ACTH testing which I guess was normal. I saw the cardiologist, who said it wasn't cardio. I had had an echocardiogram in the hospital and EKG monitoring. Cardio sent me to neurology, the PNRN did a basic neurological exam and drew blood for disease markers such as Lupus, sjorgens, hepatitis, ect. All disease markers came back negative, but my GFR was at 11 again and creatinine was 4.25, BUN 50 along with an elevated ACE level. They called me and said I sarcoidosis. I really don't have any of the primary S/S of this autoimmune disease. I don't know where to go from here, they are referring me to another neurologist at a bigger hospital. I can't live my normal life, can't walk on my feet due extreme pain and I pass out at least 2x a week, which is not good for my old body. My BP upon laying and sitting runs like 117/72, upon standing it drops to like 70/50-50/30. I am on 0.1 mg of florinef, I tried increasing it but then my legs swelled up for a gain of 23#. I talked to Mayo Clinic today and all there specialists are booked out thru December. I have to be able to work, I can't stay home any longer than September 8th! Please advise me!
  • Memory loss (blockade)
    I was on a very long and unpleasant car trip (driving 900km from A to B), that started with 6 hours long border crossing, that involved occasional pushing of a heavy car in order to spare fuel. After that, another 8 hours of driving. I developed a spasm in the area of my low back pain.

    When we arrived at the destination, I asked my wife (of 60+kg) to press my back in that area with her foot. I did not pay attention how exactly she was doing that and she did it by applying stronger pressure, and over the whole spinal area, provoking strong pain in one moment, instead of a relief.

    This happened 6 days ago (10 Aug 2014).

    I went to bed after applying quite a big amount of Diclofenac gel on my back, and I did not get up for the next 36 hours, and was mainly sleeping, however, the whole muscular area was in a spasm and on certain moves very painful after that 'rest'.

    The place where I am now is quite remote, and doctors are not available. As the condition was really bad / painful, I decided to take an advice from a cousin, and started to take the Diclofenac 50 mg orally; and the advice was that it is allowed to take one tablet every 6 hours = 200 mg/day. This has had a good effect and the pain disappeared, except in a mild intensity on certain moves, in that area where I felt the strong pain during my wife's manipulation of my back (basically what happened was that she used her full weight to step on my back, trying to lower the weight by supporting herself with her arms opposed to a piece of furniture which was laid parallel to my laying position, which I think caused the force on my spinal chord to be not vertical, but under an angle).

    Anyway, after 5 tablets of 50mg Diclofenac taken in 6 hours intervals, and as I was feeling better I decided to stop with using the Diclofenac. However, I continued to take Diclofenac 50 mg next day as the back pain returned with greater intensity.

    As this time I read on the Diclofenac package that the maximum dosage should be 150 mg/day, I used it for 2 days in 8 hours interval. This kept the level of pain bearable i.e. not intense and appearing only with that specific move / bending of my body. I was also swimmming in the sea, which in general did not make the situation with the pain worse.

    Why am I writing this report?

    I noticed yesterday, when I had taken Diclofenac 50mg already 6 times in the 8hrs interval, that I had a strange memory blockage: I was watching a movie with a famous actor, and I could not remember the name of the actor. Then I realised, I cannot remember the name of another famous actor, of whom I was reading in newspapers a lot these last few days, and we were talking about that few times.

    Then I thought of another famous actor, and I could not remember his name either! (although I could remember the faces, names of the relevant movies, sequences from those movies etc, for all the 3 actors).

    I have to emphasise that the first actor's name which I realised I cannot remember I did not see during the broadcasting of the film on the TV (but had seen the photo and read the name in the newspapers on that day or a day earlier). Then I thought I could "help" myself by concentrating on that actor's most famous movie, remembering of which I do not have a problem, but that did not help retrieving the name of the actor!

    In spite of expecting to remember the names, this is still not happening.

    If it won't be the case that actor's names were not refreshed so recently, I would consider this as the result of aging, stress, lack of refreshing my memory 'on that side' as I do not watch movies too often in the last years, etc, but still in spite of that I would expect to remember those names.

    I am not obsessed with this situation, and ended up writing this after I wanted to learn more about the types of memory loss, and possible experiences in relation to the use of Diclofenac, when I read that one of the side effects is also related to memory loss.

    I have stopped now with taking the Diclofenac, and will try not to expose myself to sources of information that could help remembering those particular names, to see if and when I will possibly remember these particular names "on my own".

    I did not obsessively try to see if I remember or not remember some other names, but have 'tested' my memory by trying to remember some names of actors I would expect to remember with less chances than those names that instigated this situation, and basically had no problem to remember those 'less expected to remember' names...

    Can this be a 'good' time to discuss seriously about testing myself for early signs of Alzheimer's disease or something similar?
  • Bone pain localized to poison ivy rash
    I am having a moderate to strong reaction to poison ivy exposure. I have a localized rash with blistering, swelling and inflammation similar to cellulitis. The rash has been progressing for about a week. The blisters are not weeping or oozing. The area is cleaned daily with neem oil soap. Coincident with the rash, I have a persistent ache/pain in my lower forearm, wrist and hand that is responding weakly to Aleve and pretty much unresponsive to acetaminophen.
  • Xanax bed wetting will it stop and do i wear diapers or die (1 response)
    I am on the very edge of crazy. So starting this is pushing ne way over. I'm 49 for crap sakes. I am so tired of the pain in my body and I am just tired, this is the last slap I can't anymore. Naturally alcohol I am sure is just about the end game along with cuts.
    Just want to bleed out and not hurt anymore and be so scared to leave my house or sleep. I just want to sleep forever.
  • Penicillin vk induced drowsiness
    I have been taking Penicillin VK and Acetaminophen for a severe pain I had been feeling in my ear. It's been 48 hours since I started taking them. Within the first 24 hours the pain had calmed down and I was feeling normal. However, since day 2 started, I have been feeling really drowsy. I keep falling asleep with no reason or desire to sleep. I just wanted to put this side effect out there for anyone else who might be feeling the same.
    I am a male, 28years old, athletic build, 6 foot.

More reviews for: Diclofenac Sodium, Tylenol

Comments from related studies:

  • From this study (1 year ago):

  • This is a mild attack of what has happened twice before (in 2007 & 2009) when the breathlessness was extreme and the discomfort was actually severe pain in left side of chest and across back of neck. Then checked in hospital and stated to not be a heart attack but bronchial hyper-reactivity/asthma. Returned periodically since them. This attack more severe than these others but less than 2007 or 2009.

    Reply

  • From this study (2 years ago):

  • I THINK I'M DYING

    Reply

  • From this study (2 years ago):

  • i THINK I'M DYING

    Reply

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Complete drug side effects:

On eHealthMe, Diclofenac Sodium (diclofenac sodium) is often used to treat arthritis. Tylenol (acetaminophen) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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