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Review: Diflucan and Valtrex

This review analyzes the effectiveness and drug interactions between Diflucan and Valtrex. It is created by eHealthMe based on reports of 1,504 people who take the same drugs from FDA and social media, and is updated regularly.

Get connected: join a mobile support group for people who take Diflucan and Valtrex >>>

What are the drugs

Diflucan (latest outcomes from 17,693 users) has active ingredients of fluconazole. It is often used in vaginal yeast infection.

Valtrex (latest outcomes from 16,433 users) has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes.

On Oct, 13, 2014: 1,504 people who take Diflucan, Valtrex are studied

Diflucan, Valtrex outcomes

Drug combinations in study:
- Diflucan (fluconazole)
- Valtrex (valacyclovir hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Diflucan is effective33.33%
(2 of 6 people)
(2 of 2 people)
(2 of 2 people)
(0 of 1 people)
Valtrex is effective50.00%
(2 of 4 people)
(2 of 2 people)
(1 of 1 people)
(4 of 4 people)
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
PneumoniaSepsisGraft Versus Host DiseaseDrowsinessBreath OdourHiatus HerniaWeight DecreasedPain
Renal Failure AcutePyrexiaPyrexiaGamblingHepatic FailureVitamin D DecreasedPyrexia
Febrile NeutropeniaThrombocytopeniaBlood Alkaline Phosphatase IncreasedLiver Function Test AbnormalVomitingMusculoskeletal DiscomfortNausea
PyrexiaFebrile NeutropeniaGamma-glutamyltransferase IncreasedSuicide AttemptWeight DecreasedDepressionAnxiety
SepsisVomitingDepressionPalpitationsHerpes SimplexInsomniaVomiting
NeutropeniaCytomegalovirus Test PositiveAcute Graft Versus Host DiseaseAnxietyGastrooesophageal Reflux DiseaseSuicide AttemptDiarrhoea
AnaemiaViral Haemorrhagic CystitisCholelithiasisBiliary DyskinesiaGastritisNightmarePneumonia
ThrombocytopeniaInterstitial Lung DiseaseDrug IneffectiveGallbladder Non-functioningDrowsinessHallucination, AuditoryAnaemia
PancytopeniaBlood Alkaline Phosphatase IncreasedCerebral ToxoplasmosisPainGerdHerpes ZosterFatigue
RashWhite Blood Cell Count DecreasedAnxietyCholecystitis ChronicDehydrationGastric DisorderFebrile Neutropenia

Drug effectiveness by gender :

Diflucan is effective44.44%
(4 of 9 people)
(2 of 2 people)
Valtrex is effective66.67%
(6 of 9 people)
(3 of 3 people)

Most common drug interactions by gender * :

VomitingFebrile Neutropenia
Febrile NeutropeniaPain
Osteonecrosis Of JawDiarrhoea

Drug effectiveness by age :

Diflucan is effectiven/an/a0.00%
(0 of 1 people)
(2 of 4 people)
(0 of 3 people)
(1 of 2 people)
(2 of 2 people)
(1 of 4 people)
Valtrex is effectiven/an/a100.00%
(1 of 1 people)
(1 of 2 people)
(2 of 4 people)
(1 of 2 people)
(3 of 3 people)
(1 of 4 people)

Most common drug interactions by age * :

DizzinessVomitingFebrile NeutropeniaChest PainFatiguePainPyrexiaPneumonia
FatigueDiarrhoeaBlood Bilirubin IncreasedNauseaAnaemiaPyrexiaPainPyrexia
Type 2 Diabetes MellitusMental Status ChangesPlatelet Count DecreasedDiarrhoeaDehydrationAnxietyAnxietyFebrile Neutropenia
Chest PainHypoxiaHaemoglobin DecreasedNeck PainDyspnoeaNauseaBack PainNausea
Cerumen ImpactionEpistaxisBlood Creatinine IncreasedAstheniaMulti-organ FailureOsteonecrosis Of JawVomitingDiarrhoea
Blood Cholesterol IncreasedSinusitis FungalRenal Failure AcuteCholecystitisGastrointestinal HaemorrhageGeneral Physical Health DeteriorationNeutropeniaAsthenia
Blood Triglycerides IncreasedTachycardiaAnxietyAbdominal Pain UpperNeutropeniaAnaemiaAnaemiaThrombocytopenia
Bundle Branch Block RightDisseminated Intravascular CoagulationPyrexiaPainProctalgiaVomitingOsteoarthritisVomiting
Back PainFebrile NeutropeniaDiarrhoeaDyspnoeaHyperglycaemiaHypertensionNauseaFatigue
AcidosisPneumoniaSepsisOedema PeripheralHeadacheFebrile NeutropeniaHypokalaemia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Diflucan and Valtrex?

Get connected! Join a related mobile support group:
- support group for people who take Diflucan and Valtrex
- support group for people who take Diflucan
- support group for people who take Valtrex

Comments from related studies:

  • From this study (2 years ago):

  • I take the diflucan, valtrex, and depoProvera intermittently, as needed. The others I take daily.


  • From this study (2 years ago):

  • I discontinued Welbutrin 6 months ago, and I discontinued
    by counting out the grains and decreasing over a one year period
    Cymbalta 4 weeks ago and panic attacks began


Post a new comment    OR    Read more comments

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Complete drug side effects:

On eHealthMe, Diflucan (fluconazole) is often used to treat vaginal yeast infection. Valtrex (valacyclovir hydrochloride) is often used to treat genital herpes. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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