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Review: Dilaudid and Methotrexate





Summary: drug interactions are reported among people who take Dilaudid and Methotrexate together.

This review analyzes the effectiveness and drug interactions between Dilaudid and Methotrexate. It is created by eHealthMe based on reports of 445 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Dilaudid and Methotrexate >>>

What are the drugs

Dilaudid has active ingredients of hydromorphone hydrochloride. It is often used in pain. (latest outcomes from Dilaudid 10,263 users)

Methotrexate Sodium has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate Sodium 7,840 users)

On Nov, 25, 2014: 444 people who take Dilaudid, Methotrexate Sodium are studied

Dilaudid, Methotrexate Sodium outcomes

Drug combinations in study:
- Dilaudid (hydromorphone hydrochloride)
- Methotrexate Sodium (methotrexate sodium)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Dilaudid is effective100.00%
(1 of 1 people)
0.00%
(0 of 1 people)
100.00%
(1 of 1 people)
n/an/an/an/an/a
Methotrexate Sodium is effectiven/an/an/an/a50.00%
(1 of 2 people)
n/an/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
NauseaInsomniaMetastatic Gastric CancerRheumatoid ArthritisMetastatic Gastric CancerMetastatic Gastric CancerHypertensive EmergencyPain
HeadacheArthralgiaDysphagiaImpaired HealingDysphoniaDysphoniaTricuspid Valve IncompetenceNausea
DyspnoeaPulse AbnormalDysphoniaNephrolithiasisDysphagiaDysphagiaVentricular HypertrophyFatigue
PyrexiaSleep DisorderGastric CancerGastric CancerGastric CancerGastric CancerAortic Valve IncompetencePyrexia
SomnolenceSomnolencePneumonia AspirationCrohn's DiseaseArthralgiaTracheobronchitisPulmonary Valve IncompetenceAnxiety
PneumonitisProcedural NauseaMetastases To Lymph NodesUrosepsisNeuropathic PainMetastases To Lymph NodesMitral Valve IncompetenceAnaemia
Blood Bilirubin IncreasedPost Procedural HaemorrhageTracheobronchitisBack PainMusculoskeletal StiffnessCitrobacter InfectionCardiac Failure CongestiveBone Disorder
HypernatraemiaNeuromaMusculoskeletal StiffnessEctopic PregnancyAnxiety PostoperativePneumonia AspirationDiastolic DysfunctionPleural Effusion
ArthralgiaNervous System DisorderCitrobacter InfectionWound InfectionCachexiaGastrointestinal StenosisWeight IncreasedDyspnoea
HypotensionPainHepatic Neoplasm MalignantAbdominal Wound DehiscenceAphagiaHepatic Neoplasm MalignantPulmonary HypertensionOsteonecrosis Of Jaw

Drug effectiveness by gender :

FemaleMale
Dilaudid is effective100.00%
(1 of 1 people)
50.00%
(1 of 2 people)
Methotrexate Sodium is effectiven/a50.00%
(1 of 2 people)

Most common drug interactions by gender * :

FemaleMale
PainVomiting
NauseaPyrexia
AnxietyFatigue
Bone DisorderNausea
Oedema PeripheralAbdominal Pain
Osteonecrosis Of JawRenal Failure Acute
FatigueDizziness
Pleural EffusionColitis
AnaemiaHeadache
OsteomyelitisDyspnoea

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Dilaudid is effectiven/an/an/an/an/a20.00%
(1 of 5 people)
n/a100.00%
(1 of 1 people)
Methotrexate Sodium is effectiven/an/an/an/an/a25.00%
(1 of 4 people)
n/a0.00%
(0 of 1 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/aSomnolenceNauseaPainDyspnoeaJoint DislocationPain
HypernatraemiaHeadacheCrohn's DiseasePainPainOedema Peripheral
Blood Bilirubin IncreasedDyspnoeaVomitingNauseaPleural EffusionBone Disorder
Pneumonia Respiratory Syncytial ViralPyrexiaArthralgiaOsteomyelitisAbdominal PainMetastases To Bone
HypotensionDehydrationPulmonary EmbolismOsteonecrosis Of JawOsteopeniaEmotional Distress
AstheniaVomitingOedema PeripheralDecreased InterestLung DisorderAnxiety
PneumonitisHydrocephalusDyspnoeaAnxietyDiarrhoeaGait Disturbance
Acute Respiratory Distress SyndromeHypertensionMuscular WeaknessGeneral Physical Health DeteriorationFoot FractureChronic Obstructive Pulmonary Disease
Clostridial InfectionSubclavian Vein ThrombosisIncreased Tendency To BruisePneumoniaSinusitisDeformity
AphasiaWithdrawal SyndromePeptic Ulcer HaemorrhagePyrexiaSpinal OsteoarthritisPyrexia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Dilaudid and Methotrexate?

You are not alone! Join a related mobile support group:
- support group for people who take Dilaudid and Methotrexate
- support group for people who take Dilaudid
- support group for people who take Methotrexate Sodium

Can you answer these questions (Ask a question):

  • Hlab27 antigen and unexplained scratches caused by accutane
    Guinea pig user of Accutane 1982. Experimental drug (told at that time) when a woman hits menopause we are not sure what will happen. I have hit early menopause 42 to be exact. Conjunctivitis, unexplained swelling in fingers, toes, kness, pseudogout (not normal according to my rheumatologist) unexplained scratches in same location, forearms, lower thigh (by knee) fingers. Scratches always are in a line with a break in the line. When a woman hits menopause hormones cease and when this happens the path that Accutane takes to cease sebaceous gland function, skin proliferation ceases. Therefore, my friends the HLA B27 (abnormal antigen targeted for skin proliferation does not know where to go so it randomly attacks whatever organ it chooses. Accutane if I remember correctly and I do have proof, permanently alters DNA. There is no other way orally ingesting a retinolic acid it could control skin, hormonal cesessation. I have only been diagnosed thus far with psoriatic arthritis with no other explanations for these other symptoms. I wonder why this is and I also wonder why dermatologists refuse to take a biopsy of my skin to rule out cell skin proliferation dysfunction. What will this damaging drug attack next. Do no be fooled by Dr.s who tell you that you took this drug so long ago how could this be. Well folks, it is because it has already changed your DNA to the HLAB27 antigen. My question also is, what was supposed to be where this abnormal DNA antigen is and how come this antigen only shows up at menopause. My disease (autoimmune) is progressive) and has already attacked nervous, muscle, skin, joints etc. Interesting
  • Anyone develop burning mouth syndrome taking exalgo
    started on ER meds for pain in jan 2014; stomach pain; continued trying diff ones; got to exalgo 8mg thought had sore throat and med didn't work ; went to 12 mg and gums bleeding, swollen, mouth burning has yet to stop since beginning of aug 2014. anyone experience similar and resolutions???
  • Has anybody had multi lobar pneumonia from reaction to methotrexate?
    Bilateral multilobar pneumonia - rheumatologist considers it was caused by a reaction to methotrexate I was taking for ankylosing spondylitis and I was lucky to survive. Anyone have this and later shown to have scarring of the lungs?
  • I am a 56 year old female with rheumatoid arthritis. i also have found out i have osteoporosis. i keep getting right breast sensitivity also tingling and tenderness in right scapula area... (2 answers)
    I am a 56 year old female with tingling in my right shoulder blade and some tenderness. I have occasional breast discomfort in the same side and sometimes my rt. nipple feels sensitive. If I touch the area, the symptom on the nipple vanishes. at times the tingling travels into my neck and symptoms seem more noticeable in the evening. If I shower in a warm shower the symptoms will vanish for a time.. All my mammograms have been normal and never miss any but it has me very worried. I check my breasts often for lumps. From time to time it also seems like I have tenderness along the sternum on that side. I have rhematoid arthritis as well as was recently told I have osteoporosis. I had a thoracic x-ray and they can see loss of bone density and some vertebrae degeneration. Take methotrexate each week and folic acid every day....Any ideas out there???? Thanks
  • Can i take marijuana while taking gilenya
    Hello i would like to know if is safe to have marijuane with gilenya and methotraxate

More questions for: Dilaudid, Methotrexate Sodium

You may be interested at these reviews (Write a review):

  • Humira: my experience
    I have had some form of arthritis probably since birth. My father and maternal grandfather had some form of arthritis. I began to realize pain in both ankles if I stood or walked too long.

    I began taking many NSAIDs when I was around 22. I've done gold, prednisone (twice), plaquenil, butazoidin, sulfasalazine, etc. My best results came with methotrexate after I got cellulitis in my knee (scratch it while kayaking in the summer, fiberglass boat). It dropped my sed rate from over 100 to 35 or so within a few months. I continued with MTX from 1977 to 2000 when my MD suggested Enbrel and stopping MTX. That was a VERY bad decision. Enbrel appeared to mask the disease for a few years. I had my left MCP replaced in 2004, my right heel debrided in 2010, and both my TMJs replaced in 2012. I strongly believe that if I had kept with the MTX it would have delayed those changes. Additionally, in 2011 I was in a bus crash returning from RAGBRAI. I got knocked out from three to six minutes. I had a nasty concussion that lasted 2+ years. Towards the end of the third year post accident I started exercising more aggressively. After doing several 40, 50, and 60 miles rides, I took a leisurely 50 mile ride around Boston at night. Two days later I had a spinal edema. So much for biking and other active sports! :-(

    I have continued with MTX. Late 2013 my MD increased my MTX to .8/week. I had been taking .6/week. I stopped taking Enbrel and switched to Humira in early 2014. I took it for a few months before my doc and I realized it was not doing any better than Enbrel. I tried Humira for three months but it did not seem to work any better than Enbrel. In early June I stopped Humira and waited a few weeks before I started Otezla. I stopped Oterzla on 9/15/14 because it made me depressed and allowed my morning stiffness to get much worse.

    I started prednisone again from the start of July. By mid-August I told my MD that I was screaming louder than I ever had; my dog was very startled. I stopped it gradually over the next two weeks. Meanwhile, the Otezla made me feel awful.

    My MD is going to get me onto another injectable that I take monthly. I forget its name.
  • Sepsis hallucinations misdiagnosed
    I was admitted to the hospital at 10 p.m., with a total bowel blockage caused by scar-tissue adhesions. I had first gone to the ER at 3 a.m. that morning, but the ER doc misdiagnosed my condition as constipation. I was in extreme pain and also too weak to tell my husband when he first came home that I needed to return to the ER. By the time I returned, I became violently nauseated, and vomited repeatedly. Then a gastro-nasal tube was forced down my nose and into my stomach. I began hallucinating at approximately 5 p.m. the following day. I did not realize I was hallucinating, and thought my experiences were real. Some were quite coherent, such as believing there was a book sitting on table at home with a photo on the front showing a sculpture in white marble of a woman's hands holding the Bible, with barbed wire wrapped around her hands. I thought the sculpture had won the Nobel prize, and the book was the biography of the sculptor, whose mother had gone to extraordinary lengths to keep him safe from the Nazis. Some may actually have occurred during dreams, and were wildly improbable, but I don't recall ever going to sleep. At one point, I thought I was at a rest stop on the NJ turnpike, and saw the Nobel-winning sculptor there, working on a wood sculpture. The sculptor turned out to be the maintenance man on the hospital floor. I pulled out the naso-gastral tube three times, but was unaware that I had done so, although I do remember believing that I was buried beneath peat moss and feeling suffocated as I clawed my way out. I also thought I was at a party being given by a law firm which had sold its building to a school for gifted children, but I (also a lawyer) had been deposited there by my nurse and her boyfriend, who were supposed to have taken me to the OR. Some scenes from a book I had been reading made their way into my delusions, which were so real to me that I actually called some of the people involved later on and asked if the events had really happened. The hallucinations began before surgery and continued afterward. When I awoke from anesthesia, I thought the hospital staff was painting the doors to my upstairs bathroom, a project I'd been involved with before the blockage struck. I asked them how they knew what colors to use. They thought I was joking, and confirmed that they had gotten the colors right. Finally a neurologist was summoned, and I told her I was on the passenger ramp at La Guardia airport (instead of in a hospital in NC), and that I'd been born in Havana, Cuba (instead of Baltimore, MD.) I believed myself to be a member of the ruling party in Cuba (pre-Castro) and during an outdoor ceremony, an earthquake had struck, causing ancient monuments to come tumbling down. Later, I was bobbing in harbor waters near a huge ocean liner, with plastic bottles and other detritus floating by. The foregoing are only a small sample of the multitude of hallucinations. Occasionally, I was only an observer of astonishing events, but usually I was a participant. I recognized my husband and friends, but told them about many of these events, believing they had happened. The neurologist diagnosed clonazepam withdrawal. My other doctors later said this was unlikely, as I took clonazepam in small amounts on an erratic schedule, and was not dependent on the drug, although my prescription called for 3 mg. daily. Physician friends said my symptoms were more likely the result of sepsis. I did contract a urinary-tract infection from the catheter, and was being given antibiotics. Additionally, the nature of my underlying condition, and the delay in diagnosis and treatment, may have contributed to the sepsis. Hallucinations occur in only a very small percentage of sepsis sufferers, and in only a small percentage of those withdrawing suddenly from clonazepam. However, I do fit the profile of those who do experience hallucinations with sepsis, being female and aged 62 at the time of this description. After the three-day period, I returned to normal, although believing that my hallucinations had been real persisted for some days afterward. I recovered quickly from the surgery, although the pain persisted for a while, and I was walking easily (dragging my IV with me) through the hospital halls. This was the ONLY symptom I had. Not all the hallucinations were unpleasant -- in fact, they were highly interesting -- but they were incredibly complex. I still remember all the details, better than I remember what actually happened yesterday. Except for the urinary-tract infection, I had no other adverse effects from hospitalization -- no fever, chills, nausea, sweating, headaches, trembling or anything of that kind. The bowel blockage and the surgery were of course not fun, but in a way the hallucinations were fascinating. My own feeling, and that of the doctors who know me and my medical issues, is that my experiences were caused by sepsis, not clonazepam withdrawal, and the antibiotics I was given are probably what saved me.
  • Psoratic arthritis and trigeminal neuralgia
    hi i suffer from psorisis and psoratic athritis i was just diagnosed with trigeminal neuralgia i was looking for the connection between the two and i see that there is one from your study
    the thing is all 13 people in the study said to have psoriatic arthropathy yet only one said to have psoratic arthritis yet to the best of my knowledge it is the same condition just a diffrent name which means all those studied have psoratic arthritis like me
    also i have not been taking those medicines in the study yet i have the same condition so if you take me into account could be the oly conecction between all of us is the psorisis and psoratic arthritis and not the medicine
  • Trinesha white need medical care advice on if it is possible to mix two medicine together
    Can they be able to mix trinesha white need medical care advice on if it is possible to mix two medicine together
  • Spiriva caused me to swell up like a hippo.
    My Doctor prescribed spiriva to help me breathe due to asthma/cold. I never smoked but my parents and friends were heavy smokers. I used the spiriva 3 times. Once a day for 3 days then I started swelling in my ankles and the swelling continued until my face, hands arms... basically I was so swollen I gained 29 pounds in two days. My doctor put me on lasix and potassium for several weeks. I quit using the spiriva when my other doctor asked if I was on any new meds. Spiriva was the only new medicine. When I stopped using it the swelling went away.

More reviews for: Dilaudid, Methotrexate Sodium

Comments from related studies:

  • From this study (1 year ago):

  • Bone density scan, negative, osteopenia
    seronegative RA
    musculo-skeletal stiffness, extreme pain
    3 stents in Right Coronary Artery
    Moderate calcification of aorta
    spinal stenosis

    Reply

  • From this study (1 year ago):

  • Sleep Apnea - treated with Cpap.

    Reply

Complete drug side effects:

On eHealthMe, Dilaudid (hydromorphone hydrochloride) is often used to treat pain. Methotrexate Sodium (methotrexate sodium) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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