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Review: Enbrel and Prednisone





Summary: drug interactions are reported among people who take Enbrel and Prednisone together.

This review analyzes the effectiveness and drug interactions between Enbrel and Prednisone. It is created by eHealthMe based on reports of 15,397 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Enbrel and Prednisone >>>

What are the drugs

Enbrel has active ingredients of etanercept. It is often used in rheumatoid arthritis. (latest outcomes from Enbrel 175,525 users)

Prednisone has active ingredients of prednisone. It is often used in rheumatoid arthritis. (view latest outcomes from 150,015 users)

On Dec, 14, 2014: 15,397 people who take Enbrel, Prednisone are studied

Enbrel, Prednisone outcomes

Drug combinations in study:
- Enbrel (etanercept)
- Prednisone (prednisone)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Enbrel is effective0.00%
(0 of 4 people)
25.00%
(2 of 8 people)
0.00%
(0 of 2 people)
100.00%
(3 of 3 people)
33.33%
(3 of 9 people)
62.50%
(5 of 8 people)
0.00%
(0 of 2 people)
n/a
Prednisone is effective60.00%
(3 of 5 people)
40.00%
(2 of 5 people)
20.00%
(1 of 5 people)
100.00%
(1 of 1 people)
54.55%
(6 of 11 people)
80.00%
(4 of 5 people)
50.00%
(3 of 6 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
ArthralgiaPneumoniaPneumoniaRheumatoid ArthritisRheumatoid ArthritisPneumoniaPneumoniaInjection Site Reaction Nos
PyrexiaOedema PeripheralRheumatoid ArthritisPneumoniaArthralgiaRheumatoid ArthritisSinusitisRheumatoid Arthritis
HeadacheDrug IneffectiveOedema PeripheralCondition AggravatedPneumoniaPyrexiaPainInjection Site Haemorrhage
NauseaArthralgiaDrug IneffectiveArthralgiaDrug IneffectiveUrinary Tract InfectionCataractDrug Ineffective
PneumoniaRheumatoid ArthritisArthralgiaHeadachePyrexiaHypertensionIntervertebral Disc ProtrusionDermatitis Nos
DyspnoeaDyspnoeaPleural EffusionDrug IneffectiveCondition AggravatedMyocardial InfarctionLung NeoplasmPyrexia
VomitingHeadacheWeight DecreasedPyrexiaPneumonia NosDehydrationLymphadenopathyArthralgia
Weight DecreasedPainPelvic PainParaesthesiaFallRenal Failure AcuteNauseaAsthenia
FatigueFatigueDepressionCellulitisPleural EffusionDeep Vein ThrombosisAphthous StomatitisNausea
Drug IneffectiveCondition AggravatedVaginal HaemorrhagePainDiverticulitisBronchitisSystemic Lupus ErythematosusHeadache Nos

Drug effectiveness by gender :

FemaleMale
Enbrel is effective33.33%
(10 of 30 people)
50.00%
(3 of 6 people)
Prednisone is effective48.39%
(15 of 31 people)
71.43%
(5 of 7 people)

Most common drug interactions by gender * :

FemaleMale
Injection Site Reaction NosRheumatoid Arthritis
Injection Site HaemorrhageInjection Site Reaction Nos
Rheumatoid ArthritisDrug Ineffective
Drug IneffectiveArthralgia
Dermatitis NosPyrexia
PyrexiaDermatitis Nos
ArthralgiaPneumonia Nos
NauseaCondition Aggravated
Headache NosAsthenia
AstheniaCough

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Enbrel is effectiven/an/a0.00%
(0 of 8 people)
0.00%
(0 of 3 people)
30.00%
(3 of 10 people)
15.00%
(3 of 20 people)
43.75%
(7 of 16 people)
0.00%
(0 of 4 people)
Prednisone is effectiven/an/a0.00%
(0 of 8 people)
0.00%
(0 of 10 people)
16.67%
(2 of 12 people)
36.84%
(7 of 19 people)
60.00%
(9 of 15 people)
40.00%
(2 of 5 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Neonatal Respiratory Distress SyndromePyrexiaPyrexiaInjection Site Reaction NosInjection Site Reaction NosInjection Site Reaction NosInjection Site Reaction NosInjection Site Reaction Nos
Premature BabyRheumatoid ArthritisHodgkin's DiseaseRheumatoid ArthritisInjection Site HaemorrhageInjection Site HaemorrhageInjection Site HaemorrhageDrug Ineffective
Congenital Cystic Kidney DiseaseConvulsionInjection Site Reaction NosVaginal HaemorrhageRheumatoid ArthritisRheumatoid ArthritisRheumatoid ArthritisRheumatoid Arthritis
Drug Exposure During PregnancyBrain OedemaDrug IneffectivePelvic PainPyrexiaHeadache NosUpper Respiratory Tract Infection NosDermatitis Nos
Respiratory DistressStreptococcal InfectionHeadacheNauseaUpper Respiratory Tract Infection NosDrug IneffectivePyrexiaInjection Site Haemorrhage
Otitis MediaCerebral HaemorrhageAnaphylactic ReactionPremature LabourHeadache NosAstheniaHeadache NosPyrexia
Reflux NephropathyFatigueCoughSquamous Cell Carcinoma Of The CervixDermatitis NosDermatitis NosAstheniaArthralgia
Secondary HypertensionCondition AggravatedSomnolenceDyspnoea NosDrug IneffectiveArthralgiaDermatitis NosCough
Heart Rate AbnormalVomiting NosInjection Site PainInjection Site HaemorrhageArthralgiaUpper Respiratory Tract Infection NosSinusitis NosAsthenia
Procedural ComplicationNauseaDiplopiaInjection Site ErythemaCoughNauseaDrug IneffectivePain Nos

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Enbrel and Prednisone?

You are not alone! Join a related mobile support group:
- support group for people who take Enbrel and Prednisone
- support group for people who take Enbrel
- support group for people who take Prednisone

Recent conversations of related support groups:

Can you answer these questions (Ask a question):

More questions for: Enbrel, Prednisone

You may be interested at these reviews (Write a review):

  • Hair loss with enbrel
    I have been on Enbrel for 4 months and started seeing significant hair thinning at the second month of treatments (50 mg once per week). My Rhuematologist suggested 800 mcg of folic acid. I am still losing hair although I am feeling so much better.
  • Etanercept and irritability
    I have been on Etanercept for 8 years for Psoriasis. Previous to this I was on
    Methotrexate, Cyclosporine, Retinodes and ACTH injections.Since being on 25mg twice a week I have been 98% clear.The only side effect to date is "Irritability" which lasts about 24hrs.
    This Drug has been my saving grace.
  • Prednisone rx 3,3,2,2,1,1 plan suicidal haunts all day
    I came home from the Hospitol with a 3,3,2,2,1,1 Rx.
    I took (3) and spent the rest of the day contenplating Suicide.
    The rest of the Rx went in the Toilet by 7:pm.
    I wonder how many this Killed.
  • Prednisone induced cushing's syndrome
    Prescribed Prednisone 20mg twice daily. Took for six weeks and developed weaken muscles and swollen face. Was hospitalized and informed I had severe Cushing's Syndrome. Host of problems included glucose over 400, inflammed pancreas, triglycerides over 4,000 and vision problems. Muscles were wasted and weak so fell several times. Had to regain strength and learn to walk again with physical therapy. Left with foggy thinking, fatigue, muscle myopathy and peripheral neuropathy. Also developed osteopenia. Afterwards was placed on hydrocortisone and Lyrica for pain. Later found liver damage.
  • Humira: my experience
    I have had some form of arthritis probably since birth. My father and maternal grandfather had some form of arthritis. I began to realize pain in both ankles if I stood or walked too long.

    I began taking many NSAIDs when I was around 22. I've done gold, prednisone (twice), plaquenil, butazoidin, sulfasalazine, etc. My best results came with methotrexate after I got cellulitis in my knee (scratch it while kayaking in the summer, fiberglass boat). It dropped my sed rate from over 100 to 35 or so within a few months. I continued with MTX from 1977 to 2000 when my MD suggested Enbrel and stopping MTX. That was a VERY bad decision. Enbrel appeared to mask the disease for a few years. I had my left MCP replaced in 2004, my right heel debrided in 2010, and both my TMJs replaced in 2012. I strongly believe that if I had kept with the MTX it would have delayed those changes. Additionally, in 2011 I was in a bus crash returning from RAGBRAI. I got knocked out from three to six minutes. I had a nasty concussion that lasted 2+ years. Towards the end of the third year post accident I started exercising more aggressively. After doing several 40, 50, and 60 miles rides, I took a leisurely 50 mile ride around Boston at night. Two days later I had a spinal edema. So much for biking and other active sports! :-(

    I have continued with MTX. Late 2013 my MD increased my MTX to .8/week. I had been taking .6/week. I stopped taking Enbrel and switched to Humira in early 2014. I took it for a few months before my doc and I realized it was not doing any better than Enbrel. I tried Humira for three months but it did not seem to work any better than Enbrel. In early June I stopped Humira and waited a few weeks before I started Otezla. I stopped Oterzla on 9/15/14 because it made me depressed and allowed my morning stiffness to get much worse.

    I started prednisone again from the start of July. By mid-August I told my MD that I was screaming louder than I ever had; my dog was very startled. I stopped it gradually over the next two weeks. Meanwhile, the Otezla made me feel awful.

    My MD is going to get me onto another injectable that I take monthly. I forget its name.

More reviews for: Enbrel, Prednisone

Comments from related studies:

  • From this study (8 months ago):

  • Comes in episodes every 8-14 months for 7 years with chronic pain inbetween. Genetic tests show NOD2 (Card 15) has two mutations

    Reply

  • From this study (8 months ago):

  • Trying to figure if it's the Mobic Savella or prednisone raising my Bp. It been 168/99 for 2weeks

    Reply

  • From this study (9 months ago):

  • Trying to determine if the timing of these drugs- especially the weekly mtx- should be staggered during the day to ensure they are appropriately absorbed. Periodic seizures continue- about once a quarter.

    Reply

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Complete drug side effects:

On eHealthMe, Enbrel (etanercept) is often used to treat rheumatoid arthritis. Prednisone (prednisone) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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