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Review: taking Bupropion and Escitalopram together

Summary: drug interactions are reported among people who take Bupropion and Escitalopram together. This review analyzes the effectiveness and drug interactions between Bupropion and Escitalopram. It is created by eHealthMe based on reports of 3,820 people who take the same drugs from FDA and social media, and is updated regularly.

Personalized health information: on eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 66 million people have used us. 200+ peer-reviewed medical journals have referenced our original studies. Start now >>>


You are not alone: join a support group for people who take Bupropion and Escitalopram >>>

What are the drugs

Bupropion hydrochloride has active ingredients of bupropion hydrochloride. It is often used in depression. (latest outcomes from 6,769 Bupropion hydrochloride users)

Escitalopram has active ingredients of escitalopram oxalate. It is often used in depression. (latest outcomes from 11,275 Escitalopram users)

On May, 22, 2015: 3,819 people who take Bupropion Hydrochloride, Escitalopram are studied

Bupropion Hydrochloride, Escitalopram outcomes

Drug combinations in study:
- Bupropion Hydrochloride (bupropion hydrochloride)
- Escitalopram (escitalopram oxalate)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Bupropion Hydrochloride is effective25.81%
(8 of 31 people)
(21 of 77 people)
(8 of 34 people)
(31 of 68 people)
(46 of 83 people)
(31 of 50 people)
(17 of 31 people)
(0 of 2 people)
Escitalopram is effective18.75%
(3 of 16 people)
(14 of 67 people)
(12 of 36 people)
(24 of 62 people)
(52 of 114 people)
(31 of 50 people)
(19 of 28 people)
(0 of 1 people)

Drug effectiveness by gender :

Bupropion Hydrochloride is effective44.72%
(127 of 284 people)
(35 of 91 people)
Escitalopram is effective42.81%
(122 of 285 people)
(33 of 89 people)

Drug effectiveness by age :

Bupropion Hydrochloride is effective0.00%
(0 of 1 people)
(9 of 28 people)
(26 of 113 people)
(34 of 173 people)
(34 of 163 people)
(44 of 167 people)
(15 of 71 people)
Escitalopram is effective0.00%
(0 of 1 people)
(8 of 27 people)
(20 of 99 people)
(38 of 169 people)
(31 of 156 people)
(45 of 167 people)
(13 of 65 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
NauseaDepressionNauseaAnxietyDepressionAnxietyDry MouthDepression
FatigueAnxietyVomitingPainAnxietyDepressionWeight Gain - UnintentionalAnxiety
DepressionDizzinessType 2 Diabetes MellitusInsomniaHyperhidrosisSuicidal IdeationAnaemiaPain
AgitationSuicidal IdeationDiabetes MellitusConvulsionPainDiabetes MellitusInsomniaNausea
ConvulsionNauseaDepressionDepressionHeadachePainPain In ExtremityFatigue
DizzinessHeadacheDizzinessEmotional DistressWeight DecreasedNauseaPainBack Pain
TremorPainSuicidal IdeationVomitingSuicide AttemptType 2 Diabetes MellitusOesophageal CandidiasisDiabetes Mellitus
Confusional StateFeeling AbnormalHyperglycaemiaFatigueInsomniaWeight IncreasedPancreatitisWeight Increased
RashEmotional DistressVertigoHeadacheConvulsionAmnesiaConstipationDizziness
AnxietyVomitingWeight IncreasedDyskinesiaSuicidal IdeationInjuryPneumoniaSuicidal Ideation

Most common drug interactions by gender * :

DizzinessSuicidal Ideation
Back PainHeadache
Weight IncreasedFatigue
FatigueWeight Decreased

Most common drug interactions by age * :

Type 2 Diabetes Mellitusn/aNauseaDizzinessDepressionDiabetes MellitusAnxietyDepression
Suicidal IdeationConvulsionDepressionDiabetes MellitusDepressionPainFall
Pyoderma GangrenosumAnxietyHeadacheAnxietyPainDepressionAnxiety
Pelvic PainFatigueNauseaDizzinessWeight IncreasedNauseaNausea
Urinary Tract InfectionVomitingAnxietyType 2 Diabetes MellitusAnxietySpinal OsteoarthritisTremor
Uterine LeiomyomaAbdominal Pain UpperAbdominal PainNauseaType 2 Diabetes MellitusOsteonecrosis Of JawDrug Ineffective
Tremor NeonatalPainCompleted SuicideSuicidal IdeationSuicidal IdeationDyspnoeaPneumonia
Maternal Drugs Affecting FoetusBiliary DyskinesiaCholelithiasisWeight IncreasedNauseaBone DisorderInsomnia
Extrapyramidal DisorderBack PainTremorFatigueDrug IneffectiveBack PainArthralgia
Weight IncreasedGallbladder InjuryFatigueHeadacheInsomniaPain In ExtremityFatigue

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Bupropion and Escitalopram?


You are not alone! Join a related support group:
- support group for people who take Bupropion Hydrochloride
- support group for people who take Escitalopram

Recent conversations of related support groups:

Can you answer these questions (Ask a question):

More questions for: Bupropion Hydrochloride, Escitalopram

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More reviews for: Bupropion Hydrochloride, Escitalopram

Comments from related studies:

  • From this study (4 weeks ago):

  • I started Lexapro and developed yeast infection. Took Lexapro and treated infection for a week, with not much improvement. I don't know if this is a side effect of Lexapro. The reviews do not mention this but for me the timing is ironic. If it is the Lexapro will my body straighten itself out if I keep taking it or do I need to stop taking it to feel better?


  • From this study (1 month ago):

  • I have had a painful, red, itchy rash on my skin(face) off and on for the past two years. Nothing I have tried has worked in treating it. A dermatologist told me it was Rosacea and treated it with topical hydrocordisone. It did work for a time but has since stopped working. I have since tried all kinds of treatments including topical, herbs and food for inflamation and accupuncture. It is very irritating and painful and has affected my self confidence. I personally do not think it is Rosacea because it does not appear on my face like most Roasacea does. Instead it is more on my chin, around my nose and eyes. Nothing on my cheeks. I am currently considering stopping the Wellbutrin to see if it goes away.


  • From this study (3 months ago):

  • had laser procedure to repair


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Complete drug side effects:

On eHealthMe, Bupropion Hydrochloride (bupropion hydrochloride) is often used to treat depression. Escitalopram (escitalopram oxalate) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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