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Home > Flexeril > Cymbalta > Flexeril and Cymbalta

Review: Flexeril and Cymbalta

Summary: drug interactions are reported among people who take Flexeril and Cymbalta together.

This review analyzes the effectiveness and drug interactions between Flexeril and Cymbalta. It is created by eHealthMe based on reports of 1,634 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Flexeril and Cymbalta >>>

What are the drugs

Flexeril (latest outcomes from 16,437 users) has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms.

Trend of flexeril reports

Cymbalta (latest outcomes from 49,259 users) has active ingredients of duloxetine hydrochloride. It is often used in depression.

Trend of cymbalta reports

On Nov, 25, 2014: 1,634 people who take Flexeril, Cymbalta are studied

Flexeril, Cymbalta outcomes

Drug combinations in study:
- Flexeril (cyclobenzaprine hydrochloride)
- Cymbalta (duloxetine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Flexeril is effective20.00%
(4 of 20 people)
25.00%
(5 of 20 people)
16.67%
(2 of 12 people)
17.39%
(4 of 23 people)
29.41%
(10 of 34 people)
26.67%
(4 of 15 people)
66.67%
(2 of 3 people)
33.33%
(1 of 3 people)
Cymbalta is effective31.25%
(5 of 16 people)
21.95%
(9 of 41 people)
16.67%
(2 of 12 people)
31.82%
(7 of 22 people)
33.33%
(12 of 36 people)
33.33%
(1 of 3 people)
50.00%
(2 of 4 people)
50.00%
(1 of 2 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Feeling AbnormalAnxietyDepressionNauseaDepressionCholecystitis ChronicFemur FracturePain
Aspartate Aminotransferase IncreasedDizzinessAnxietyDiabetic NeuropathyAnxietyPainColon AdenomaNausea
Alanine Aminotransferase IncreasedDepressionTemporomandibular Joint SyndromeDiabetic ComaPainGallbladder DisorderCystitisDepression
HeadacheHepatic CirrhosisVertigoHyperglycaemiaMuscle TwitchingSphincter Of Oddi DysfunctionHypothyroidismFatigue
DepressionHypersensitivityOsteonecrosisHypoglycaemiaCholecystitis ChronicPancreatitisUrinary RetentionAnxiety
Weight DecreasedCellulitisOral HerpesMental Status ChangesPancreatitisMuscle SpasmsTooth DisorderArthralgia
NauseaSphincter Of Oddi DysfunctionArthropathyChronic HepatitisSphincter Of Oddi DysfunctionVision BlurredPostmenopausal HaemorrhageWeight Increased
Hepatic Enzyme IncreasedChronic HepatitisWoundConvulsionFibromyalgiaMuscle TwitchingLymphoedemaHeadache
InsomniaPancreatic Duct StenosisCerebral CystCardiomyopathyPsychotic DisorderTremorOsteoporosisInsomnia
AgitationBile Duct StenosisAphthous StomatitisHepatic CirrhosisGallbladder DisorderFatigueLow Turnover OsteopathyDyspnoea

Drug effectiveness by gender :

FemaleMale
Flexeril is effective26.13%
(29 of 111 people)
15.79%
(3 of 19 people)
Cymbalta is effective30.43%
(35 of 115 people)
15.00%
(3 of 20 people)

Most common drug interactions by gender * :

FemaleMale
PainDepression
NauseaAnxiety
DepressionPain
AnxietyNausea
FatigueChest Pain
ArthralgiaPain In Extremity
Weight IncreasedSuicidal Ideation
HeadacheNeuropathy Peripheral
InsomniaDiabetes Mellitus
DiarrhoeaDyspnoea

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Flexeril is effectiven/an/an/a28.57%
(4 of 14 people)
7.78%
(7 of 90 people)
8.79%
(8 of 91 people)
17.65%
(12 of 68 people)
10.00%
(1 of 10 people)
Cymbalta is effectiven/an/an/a33.33%
(5 of 15 people)
9.09%
(8 of 88 people)
9.78%
(9 of 92 people)
18.84%
(13 of 69 people)
27.27%
(3 of 11 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Meningomyelocelen/aGallbladder DisorderDiabetes MellitusNauseaPainPainPain
Neural Tube DefectCholecystitis ChronicType 2 Diabetes MellitusWeight IncreasedNauseaNauseaAnxiety
Spina BifidaSphincter Of Oddi DysfunctionConvulsionHeadacheFatigueArthralgiaFatigue
TalipesPainPulmonary EmbolismType 2 Diabetes MellitusDepressionDepressionFall
Maternal Drugs Affecting FoetusPancreatitisInjuryDyspnoeaBack PainFatigueDepression
Congenital HydrocephalusType 2 Diabetes MellitusAnxietyFatigueAnxietyAnxietyNeuropathy Peripheral
ObesityAnxietyDeathDepressionAstheniaHeadacheHypertension
Type 2 Diabetes MellitusScarDepressionVomitingPain In ExtremityInsomniaAnaemia
Abortion InducedAbdominal DistensionPainArthralgiaChest PainWeight IncreasedDizziness
Congenital Central Nervous System AnomalyDepressionAdverse Drug ReactionAbdominal PainDiarrhoeaHypertensionAnhedonia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Flexeril and Cymbalta?

You are not alone! Join a related mobile support group:
- support group for people who take Flexeril and Cymbalta
- support group for people who take Cymbalta
- support group for people who take Flexeril

Recent conversations of related support groups:

  • Support group for people who take Cymbalta
    Now found out I have incompetent vein in leg which may be part of the problem had cystocopy and found cysts in kidney, then developed hypertension but no one will diagnose the pain. Now decided it is the same as diabetic neuropathy but as gp and consultant point out I am a long way from being diabetic with perfect blood glucose so thinks it's just guessing and hope

Can you answer these questions (Ask a question):

  • Cymbalta r/t autonomic neuropathy
    (Asked by a 62 year old man who has Stomach Pains, GERD, Fatique, Constipation, Dizzness, Early Satiety)
    neurotin losartan 20 mg tired all the time, dizziness, chronic constipation, stomach pains, pins and needles, diabetic type 2 hx alcoholism resolved, gerd, early satiety

  • Why would i get copd since i never smoked?
    (Asked by a 62 year old woman who has Rheumatoid Arthritis, PBC, AIH, Asthma, and takes Vitamin D, Calcium Carbonate, Anturol, Morphine Sulfate, Levothyroxine Sodium, Pyridium, Cyclobenzaprine Hydrochloride, Azathioprine, Proair Hfa, Advair Diskus 250/50, Combivent)
    I have several autoimmune disorders, I was shocked to get the COPD diagnosis since I have never smoked but I had second hand smoke first 23 years of my life. My doctor said my Autoimmune Hepatitis and Primary Biliary Cholingitis set me up for COPD.

  • I know that thallasemia can protect some people from malaria, is that the same scenerio for ebola virus as well?
    (Asked by a 57 year old woman who has No Symptoms Just Wondering, and takes Cymbalta)
    Just wondering about the relation between Thallasemia and Ebola Virus

  • What side effects from nuvigil and cymbalta creating seretonin syndrome?
    (Asked by a 53 year old woman who has Hot Red Skin On Face Neck And Back, and takes Suboxone , Nuvigil, Cymbalta)
    My dr thinks that all the drugs I'm on are causing sedition syndrome. But I have t seen where a symptom was red flushed skin?

  • Does duloxetine have shell fish in it?
    (Asked by a 54 year old man who has Depressive Symptom, and takes Duloxetine Hydrochloride)
    Ok this is ridiculous ! a simple question and i'm surprised you don't want a ss#. Simply does this drug contain shellfish?

More questions for: Cymbalta, Flexeril

You may be interested at these reviews (Write a review):

  • Numbness between toes
    (Posted by a 48 year old woman who has Numbness In Hands Or Feet, and takes Cymbalta)
    This summer I flip flops, with the strap between my toes, almost exclusively. When I switched this fall to regular shoes I noticed a strange, numb sensation between my big toe and second toe. At first I thought it had something to do with the flip flops and thought it would go away. It has been a f ...

  • Cymbalta caused joint pain
    (Posted by a 50 year old man who has Pain - Joints, and takes Cymbalta)
    I had taken Cymbalta for about 1.5 years and after taking it for a few months, I started having widespread joint pain. The joint pain has gotten worse and is becoming debilitating. Joint pain in the literature as a side affect of the drug but the joint pain seems to be permanent! I have not taken Cy ...

  • Transition from mirtazapine to cymbalta (bipolar ii) 6 week duration taken in conjunction with seroquel, propranalol and implanon
    (Posted by a 37 year old woman who has Generalized Anxiety Disorder, Bipolar 2, and takes Mirtazapine, Implanon, Propranolol Hydrochloride, Seroquel, Cymbalta)
    In early September I approached my Psychiatrist to report that I was having sleep paralysis episodes as well as insatiable appetite. I had put on about 20lb in the space of 6 months since the sleep paralysis started. My Psychiatrist opted to wean me off the Mirtazapine and onto Cymbalta. I have n ...

  • Severe night sweats and hot flashes with cymbalta?
    (Posted by a 25 year old woman who has Night Sweats, Hot Flashes, and takes Lamictal, Cymbalta)
    I am 24 years old and I have been having severe night sweats for about the last 2 and a half years. I have been on Cymbalta for about 4 and a half years. These night sweats are so severe that I typically wake up 2-4 times a night drenched in sweat where I have to change the sheets, get a new blanket ...

  • Cymbalta side effects
    (Posted by a 56 year old man who has Cymbalta Side Effects, and takes Cymbalta)
    This summer I was put on Cymbalta 65mg because of anxiety. Boy what a mistake (at least for me). I went from a fairly normal life to a life of depression, suicidal thoughts, vertigo, nausea, pain the the back and neck, no energy, no appetite, fatigue, withdrawal from life, fear of dying etc, etc, ...

More reviews for: Cymbalta, Flexeril

Complete drug side effects:

On eHealthMe, Flexeril (cyclobenzaprine hydrochloride) is often used to treat muscle spasms. Cymbalta (duloxetine hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug studies (Check your drugs):

More related studies for: Cymbalta, Flexeril

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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