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Review: Trazodone and Fluoxetine

This review analyzes the effectiveness and drug interactions between Trazodone and Fluoxetine. It is created by eHealthMe based on reports of 3,405 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: join a mobile support group for people who take Trazodone and Fluoxetine >>>

What are the drugs

Trazodone hydrochloride (latest outcomes from 6,523 users) has active ingredients of trazodone hydrochloride. It is often used in insomnia.

Fluoxetine (latest outcomes from 28,040 users) has active ingredients of fluoxetine hydrochloride. It is often used in depression.

On Jul, 24, 2014: 3,404 people who take Trazodone Hydrochloride, Fluoxetine are studied

Trazodone Hydrochloride, Fluoxetine outcomes

Drug combinations in study:
- Trazodone Hydrochloride (trazodone hydrochloride)
- Fluoxetine (fluoxetine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Trazodone Hydrochloride is effective20.00%
(4 of 20 people)
36.84%
(7 of 19 people)
53.33%
(8 of 15 people)
42.86%
(9 of 21 people)
59.26%
(16 of 27 people)
52.63%
(10 of 19 people)
73.33%
(11 of 15 people)
n/a
Fluoxetine is effective12.50%
(2 of 16 people)
23.81%
(5 of 21 people)
28.57%
(4 of 14 people)
42.11%
(8 of 19 people)
40.91%
(9 of 22 people)
36.84%
(7 of 19 people)
44.44%
(12 of 27 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
ArthralgiaType 2 Diabetes MellitusType 2 Diabetes MellitusDiabetes MellitusObesityType 2 Diabetes MellitusDepressionNausea
DepressionNauseaNauseaType 2 Diabetes MellitusType 2 Diabetes MellitusWeight IncreasedFatigueType 2 Diabetes Mellitus
Disturbance In AttentionBack PainDiabetic NeuropathyPainBlood Cholesterol IncreasedDiabetes MellitusMemory ImpairmentDiabetes Mellitus
InsomniaObesityStillbirthBlood Cholesterol IncreasedBlood Triglycerides IncreasedDiabetes Mellitus Inadequate ControlDepressed MoodDepression
Drug IneffectiveDiabetic KetoacidosisBlood Triglycerides IncreasedObesityWeight IncreasedAnxietyVision BlurredAnxiety
Blood Creatine Phosphokinase IncreasedPainDrug Exposure During PregnancyBladder DisorderChest PainObesityPanic AttackPain
Neuropathy PeripheralAgitationVulvovaginal CandidiasisBlood Triglycerides IncreasedDepressionPainVictim Of CrimeFatigue
NauseaMuscle SpasmsDiabetes MellitusBacterial InfectionOsteoporosisTardive DyskinesiaAngerHeadache
Pharyngolaryngeal PainHyperglycaemiaWeight IncreasedCardiac DisorderRib FractureDepressionStressDyspnoea
AngerWeight IncreasedUpper Respiratory Tract InfectionFungal InfectionRespiratory DistressGallbladder DisorderSomnolenceFall

Drug effectiveness by gender :

FemaleMale
Trazodone Hydrochloride is effective52.43%
(54 of 103 people)
33.33%
(11 of 33 people)
Fluoxetine is effective38.46%
(40 of 104 people)
20.59%
(7 of 34 people)

Most common drug interactions by gender * :

FemaleMale
NauseaAnxiety
Type 2 Diabetes MellitusType 2 Diabetes Mellitus
Diabetes MellitusDiabetes Mellitus
DepressionDepression
PainFatigue
HeadacheNausea
AnxietyPain
FatigueSuicidal Ideation
DyspnoeaFall
Weight IncreasedInsomnia

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Trazodone Hydrochloride is effectiven/a0.00%
(0 of 2 people)
33.33%
(1 of 3 people)
18.75%
(9 of 48 people)
36.36%
(16 of 44 people)
27.94%
(19 of 68 people)
25.45%
(14 of 55 people)
23.08%
(6 of 26 people)
Fluoxetine is effectiven/a0.00%
(0 of 2 people)
0.00%
(0 of 3 people)
14.81%
(8 of 54 people)
24.44%
(11 of 45 people)
16.92%
(11 of 65 people)
25.45%
(14 of 55 people)
11.11%
(3 of 27 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Diabetes MellitusElectrocardiogram Qt ProlongedAggressionDiabetes MellitusType 2 Diabetes MellitusDiabetes MellitusNauseaPain
AggressionBipolar DisorderSuicide AttemptType 2 Diabetes MellitusDiabetes MellitusType 2 Diabetes MellitusDepressionFatigue
Tardive DyskinesiaRespiratory Failure (excl Neonatal)Suicidal IdeationDizzinessNauseaNauseaType 2 Diabetes MellitusAnxiety
PancreatitisPulse AbsentWeight IncreasedVomitingAnxietyHeadacheFallAsthenia
Congenital Diaphragmatic HerniaInsomniaNauseaAbdominal Pain UpperDepressionDyspnoeaHeadacheFall
ConvulsionLeft Ventricular HypertrophyPersonality ChangeWeight IncreasedWeight IncreasedFatiguePainDiarrhoea
Lung Disorder NosAggressionAngerSuicidal IdeationDrug Withdrawal SyndromeDepressionPain In ExtremityDyspnoea
Peritoneal EffusionSedationAgitationPancreatitisPainChest PainAnxietyHeadache
Pleural EffusionWeight IncreasedFeeling AbnormalDepressionDrug DependenceAnxietyDiabetes MellitusConstipation
Pelvic Fluid CollectionDrug IneffectiveSomnolenceDyspnoeaHeadacheWeight IncreasedFatigueSpinal Osteoarthritis

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group:
- group for people who take Trazodone and Fluoxetine
- group for people who take Fluoxetine
- group for people who take Trazodone Hydrochloride

Comments from related studies:

  • From this study (5 months ago):

  • Pervasive developmental disorder...autism...unexplained g.i. Issues with multiple procedures only finding inflammation...prescribed sucralfate after severe vomiting which seemed to help for awhile, but cycle seems to be starting all over again...vomits often after eating

    Reply

  • From this study (7 months ago):

  • I have been diagnosed with dysautonomia dis regulation of my heart, blood pressure, and peripheral vascular system.

    Reply

Post a new comment    OR    Read more comments

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Complete drug side effects:

On eHealthMe, Trazodone Hydrochloride (trazodone hydrochloride) is often used to treat insomnia. Fluoxetine (fluoxetine hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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