Review: Isoniazid and Rifampin drug interactions
This review analyzes the interactions between Isoniazid and Rifampin. It is created by eHealthMe based on 1,030 people who have drug interactions while taking the drugs. The review uses reports from FDA and social media, and is updated regularly.
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What are the drugs
Isoniazid (latest outcomes from 7,166 users) has active ingredients of isoniazid. It is often used in tuberculosis.
Rifampin (latest outcomes from 2,104 users) has active ingredients of rifampin. It is often used in tuberculosis.
On Feb, 6, 2014: 1,030 people who reported to have interactions when taking Isoniazid, Rifampin are studied
Drug combinations in study:
- Isoniazid (isoniazid)
- Rifampin (rifampin)
Most common interactions experienced by people in the use of Isoniazid, Rifampin:(click on each outcome to view in-depth analysis, incl. how people recovered)
|Interaction||Number of reports|
|Neutropenia (an abnormally low number of neutrophils)||87|
|Renal Failure Acute (rapid kidney dysfunction)||65|
|Thrombocytopenia (decrease of platelets in blood)||47|
|Aspartate Aminotransferase Increased||42|
|Hepatitis Fulminant (life-threatening condition defined by significantly impaired liver function)||38|
|Hepatic Failure (liver failure)||37|
|Alanine Aminotransferase Increased||36|
|Nausea (feeling of having an urge to vomit)||35|
Most common interactions experienced by people in long term use of Isoniazid, Rifampin:(click on each outcome to view in-depth analysis, incl. how people recovered)
|Interaction||Number of reports|
|Somnolence (a state of near-sleep, a strong desire for sleep)||4|
|Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)||2|
|Respiratory Failure (inadequate gas exchange by the respiratory system)||2|
|Thrombocytopenia (decrease of platelets in blood)||2|
|Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)||2|
|Disturbance In Attention||2|
|Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)||1|
How effective are the drugs:
|not at all||somewhat||moderate||high||very high|
Top conditions involved for these people * :
- Hiv infection
- Pulmonary tuberculosis
- Disseminated tuberculosis
Top co-used drugs for these people * :
- Ethambutol hydrochloride
* Approximation only. Some reports may have incomplete information.
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Complete drug side effects:
On eHealthMe, Isoniazid (isoniazid) is often used to treat tuberculosis. Rifampin (rifampin) is often used to treat tuberculosis. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.
What is the drug used for and how effective is it:
- Isoniazid is used in:
- Rifampin is used in:
Other drugs that are used to treat the same conditions:
- Isoniazid alternatives:
- Rifampin alternatives:
Can you answer these questions (what is this?):
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- Could isoniazid cause a normal people epilepsy?
I got TB in 2011，I have took isoniazid and rifampin for 9 months. Last month, I found I became epilepsy.
- Treatment for chronic q fever without heart noticeable problems together with chronic lyme disease
Been on treatment with 200mg/day doxy only for 3 months, added 300mg/day rifadin for another 3 months. Had little or no improvement with doxy alone, had a little more when added rifadin. But always thought treatment was correct but dosage was not appropriate. Not enough. Had to stop because I got pr ...
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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
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