Review: Isoniazid and Rifampin
This review analyzes the effectiveness and drug interactions when people take Isoniazid and Rifampin. It is created by eHealthMe based on 1,030 reports from FDA and social media, and is updated regularly.
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What are the drugs
Isoniazid (latest outcomes) has active ingredients of isoniazid. It is used in tuberculosis, pulmonary tuberculosis, ppd skin test, latent tuberculosis, tuberculin test positive, tuberculosis skin test positive
Rifampin (latest outcomes) has active ingredients of rifampin. It is used in tuberculosis, pulmonary tuberculosis, infection, cat scratch disease, ppd skin test, mrsa infection
On Dec, 5, 2013: 1,030 people who reported to have interactions when taking Isoniazid, Rifampin are studied
Drug combinations in study:
- Isoniazid (isoniazid)
- Rifampin (rifampin)
Most common interactions experienced by people in the use of Isoniazid, Rifampin:(click on each outcome to view in-depth analysis, incl. how people recovered)
|Interaction||Number of reports|
|Neutropenia (an abnormally low number of neutrophils)||87|
|Renal Failure Acute (rapid kidney disfunction)||65|
|Thrombocytopenia (decrease of platelets in blood)||47|
|Aspartate Aminotransferase Increased||42|
|Hepatitis Fulminant (life-threatening condition defined by significantly impaired liver function)||38|
|Hepatic Failure (liver failure)||37|
|Alanine Aminotransferase Increased||36|
|Cytolytic Hepatitis (dissolution or destruction of a liver cell)||35|
Most common interactions experienced by people in long term use of Isoniazid, Rifampin:(click on each outcome to view in-depth analysis, incl. how people recovered)
|Interaction||Number of reports|
|Somnolence (a state of near-sleep, a strong desire for sleep)||4|
|Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)||2|
|Disturbance In Attention||2|
|Thrombocytopenia (decrease of platelets in blood)||2|
|Mental Disorder (a psychological term for a mental or behavioral pattern or anomaly that causes distress or disability)||2|
|Renal Failure Chronic (long lasting kidney disfunction)||1|
|General Physical Health Deterioration (weak health status)||1|
|Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi)||1|
How effective are the drugs:
|not at all||somewhat||moderate||high||very high|
Top conditions involved for these people * :
- Hiv infection
- Pulmonary tuberculosis
- Disseminated tuberculosis
Top co-used drugs for these people * :
- Ethambutol hydrochloride
* Approximation only. Some reports may have incomplete information.
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Can you answer these questions (what is this?):
- By Badbelly: How to cure isoniazid c dif colitis
(for a 47 year old woman who has Diarrhea, Colitis, and takes Isoniazid, Probiotics, Pyridoxine (vitamin B6))
Developed c dif colitis 4.5 mos into inh tx also have cvid as well as systemic lupus and ankylosing spondylitis... What can they give me?
(Number of patients like Badbelly: 343)
- By isoniad epilepsy: Could isoniazid cause a normal people epilepsy?
(for a 25 year old man who has TB, and takes Isoniazid, Rifampin)
I got TB in 2011，I have took isoniazid and rifampin for 9 months. Last month, I found I became epilepsy.
(Number of patients like isoniad epilepsy: 92)
- By LymePortugal: Treatment for chronic q fever without heart noticeable problems together with chronic lyme disease
(for a 38 year old woman who has Antibody Test Abnormal, Cytomegalovirus Antibody Positive, Lyme Disease - Chronic Persistent, Q Fever Chronic, and takes Doxycycline, Rifadin)
Been on treatment with 200mg/day doxy only for 3 months, added 300mg/day rifadin for another 3 months. Had little or no improvement with doxy alone, had a little more when added rifadin. But always thought treatment was correct but dosage was not appropriate. Not enough. Had to stop because I got pr ...
(Number of patients like LymePortugal: 498)
You may be interested at these reviews (what is this?):
- By TexasLady: Isoniazid: the downside continued
(for a 62 year old woman who has Fatigue, Dizziness (excl Vertigo), Nausea, Impaired Healing, Liver Pain, Diarrhea, Hair Thinning, Liver Pain, Skin Atrophy, and takes Isoniazid)
I also have extreme fatigue. I can sleep 8 hours and then take a 4 hour nap. I have dizziness which seems to be increasing in the last few weeks. I have nausea on and off. I have diarrhea in the morning 45 minutes after taking it. Then I am mostly constipated for the rest of the day. It seems ...
(Number of patients like TexasLady: 926)
- By TexasLady: Isoniazid--the downside
(for a 62 year old woman who has Mental Status Changes, and takes Isoniazid)
Started taking Isonizaid approximately June 10. I am having fairly severe memory loss. I am having mental confusion. I am having depression. I have weight gain. I have liver pain, but it has lessened in the last month though it was severe in the first 3 months. I have digestive issues such as ...
(Number of patients like TexasLady: 66)
Complete drug side effects:
On eHealthMe, Isoniazid (isoniazid) is often used to treat tuberculosis. Rifampin (rifampin) is often used to treat tuberculosis. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.
What is the drug used for and how effective is it:
- Isoniazid is used in:
- Rifampin is used in:
Other drugs that are used to treat the same conditions:
- Isoniazid alternatives:
- Rifampin alternatives:
NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
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