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Review: Isoniazid and Rifampin

This review analyzes the effectiveness and drug interactions between Isoniazid and Rifampin. It is created by eHealthMe based on 1,059 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

On Apr, 17, 2014: 1,059 people who take Isoniazid, Rifampin are studied

Isoniazid, Rifampin outcomes

Drug combinations in study:
- Isoniazid (isoniazid)
- Rifampin (rifampin)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Isoniazid is effectiven/a50.00%
(4 of 8 people)
100.00%
(3 of 3 people)
100.00%
(1 of 1 people)
n/an/an/an/a
Rifampin is effectiven/a50.00%
(4 of 8 people)
100.00%
(3 of 3 people)
100.00%
(1 of 1 people)
n/an/an/an/a

Drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Renal Failure Acute
(19 reports)

Pyrexia
(19 reports)

Headache
(12 reports)

Multi-organ Failure
(11 reports)

Hepatitis
(11 reports)

Cytolytic Hepatitis
(11 reports)

Convulsion
(9 reports)

Renal Impairment
(9 reports)

Stevens-johnson Syndrome
(9 reports)

Liver Disorder
(8 reports)

Pyrexia
(22 reports)

Renal Failure Acute
(22 reports)

Cytolytic Hepatitis
(18 reports)

Hepatitis Fulminant
(16 reports)

Neutropenia
(15 reports)

Stevens-johnson Syndrome
(14 reports)

Leukopenia
(14 reports)

Drug Eruption
(14 reports)

Dyspnoea
(12 reports)

Eosinophilia
(11 reports)

Ocular Icterus
(4 reports)

Convulsion
(4 reports)

Deafness
(3 reports)

Optic Neuropathy
(3 reports)

Hypoacusis
(3 reports)

Pyrexia
(3 reports)

Hepatic Failure
(2 reports)

Hepatitis Cholestatic
(2 reports)

Visual Impairment
(2 reports)

Hepatic Cirrhosis
(2 reports)

Mental Disorder
(2 reports)

Disturbance In Attention
(2 reports)

Somnolence
(2 reports)

Thrombocytopenia
(2 reports)

Cerebral Ischaemia
(1 report)

Fatigue
(1 report)

Paraesthesia
(1 report)

Hepatitis Fulminant
(1 report)

Shock
(1 report)

Pyrexia
(1 report)

Disturbance In Attention
(2 reports)

Somnolence
(2 reports)

Mental Disorder
(2 reports)

Dysarthria
(1 report)

Meningism
(1 report)

Rash Generalised
(1 report)

Tuberculoma Of Central Nervous System
(1 report)

Drug Eruption
(1 report)

Pyrexia
(1 report)

Cerebral Ischaemia
(1 report)

Stevens Johnson Syndrome
(1 report)

n/aPyrexia
(48 reports)

Immune Reconstitution Syndrome
(26 reports)

Hepatitis Fulminant
(19 reports)

Dyspnoea
(18 reports)

Hepatotoxicity
(17 reports)

Diarrhoea
(16 reports)

Renal Failure Acute
(16 reports)

Deep Vein Thrombosis
(16 reports)

General Physical Health Deterioration
(15 reports)

Tuberculosis
(15 reports)

Drug effectiveness by gender :

FemaleMale
Isoniazid is effective77.78%
(7 of 9 people)
33.33%
(1 of 3 people)
Rifampin is effective77.78%
(7 of 9 people)
33.33%
(1 of 3 people)

Drug interactions by gender * :

FemaleMale
Pyrexia
(68 reports)

Aspartate Aminotransferase Increased
(23 reports)

Nausea
(21 reports)

Cytolytic Hepatitis
(21 reports)

Alanine Aminotransferase Increased
(21 reports)

Hepatitis Fulminant
(20 reports)

Hepatic Failure
(20 reports)

Asthenia
(19 reports)

Hepatic Encephalopathy
(18 reports)

Lymphadenopathy
(18 reports)

Pyrexia
(84 reports)

Renal Failure Acute
(52 reports)

Dyspnoea
(30 reports)

Thrombocytopenia
(29 reports)

Neutropenia
(26 reports)

Cough
(22 reports)

Drug Eruption
(21 reports)

Convulsion
(21 reports)

Aspartate Aminotransferase Increased
(20 reports)

Liver Function Tests Nos Abnormal
(19 reports)

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Isoniazid is effectiven/an/an/a50.00%
(3 of 6 people)
40.00%
(2 of 5 people)
100.00%
(2 of 2 people)
n/a50.00%
(1 of 2 people)
Rifampin is effectiven/an/an/a50.00%
(3 of 6 people)
40.00%
(2 of 5 people)
100.00%
(2 of 2 people)
n/a50.00%
(1 of 2 people)

Drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Immune Reconstitution Syndrome
(5 reports)

Coagulopathy
(4 reports)

Lymphadenitis
(4 reports)

Brain Oedema
(4 reports)

Pyrexia
(4 reports)

Hepatic Failure
(4 reports)

Bovine Tuberculosis
(4 reports)

Hepatic Encephalopathy
(4 reports)

Acute Hepatic Failure
(4 reports)

Drug Exposure During Pregnancy
(3 reports)

Pyrexia
(4 reports)

Paradoxical Drug Reaction
(3 reports)

Hydrocephalus
(2 reports)

Acinetobacter Infection
(2 reports)

Stenotrophomonas Infection
(2 reports)

Central Nervous System Infection
(2 reports)

Acute Hepatic Failure
(2 reports)

Pulmonary Tuberculosis
(2 reports)

Grand Mal Convulsion
(2 reports)

Cardiac Arrest
(2 reports)

Pyrexia
(8 reports)

Drug Level Increased
(6 reports)

Renal Failure Acute
(5 reports)

Acute Hepatic Failure
(5 reports)

Paradoxical Drug Reaction
(4 reports)

Thrombocytopenia
(4 reports)

Lymphadenopathy
(4 reports)

Night Sweats
(3 reports)

Cough
(3 reports)

Cytolytic Hepatitis
(3 reports)

Pyrexia
(14 reports)

Nausea
(8 reports)

Aspartate Aminotransferase Increased
(8 reports)

Hepatic Failure
(8 reports)

Immune Reconstitution Syndrome
(7 reports)

Alanine Aminotransferase Increased
(7 reports)

Hepatic Necrosis
(6 reports)

Blood Creatine Phosphokinase Increased
(6 reports)

Vomiting
(5 reports)

Hepatomegaly
(5 reports)

Pyrexia
(32 reports)

Immune Reconstitution Syndrome
(13 reports)

Renal Failure Acute
(12 reports)

Hepatitis Fulminant
(11 reports)

Deep Vein Thrombosis
(10 reports)

Lymphadenopathy
(10 reports)

General Physical Health Deterioration
(9 reports)

Cough
(9 reports)

Cytolytic Hepatitis
(8 reports)

Pulmonary Embolism
(8 reports)

Pyrexia
(16 reports)

Vomiting
(12 reports)

Hepatitis Fulminant
(8 reports)

Hepatic Encephalopathy
(8 reports)

Aspartate Aminotransferase Increased
(8 reports)

Diarrhoea
(8 reports)

Anaemia
(7 reports)

Hepatitis
(7 reports)

Cough
(6 reports)

Dyspnoea
(6 reports)

Renal Failure Acute
(19 reports)

Drug Eruption
(18 reports)

Pyrexia
(17 reports)

Leukopenia
(16 reports)

Neutropenia
(13 reports)

Convulsion
(12 reports)

Stevens-johnson Syndrome
(12 reports)

Dyspnoea
(11 reports)

Pruritus
(10 reports)

Blood Bilirubin Increased
(10 reports)

Pyrexia
(45 reports)

Thrombocytopenia
(23 reports)

Liver Function Tests Nos Abnormal
(18 reports)

Renal Failure Acute
(16 reports)

Hepatocellular Damage
(15 reports)

Cholestasis
(15 reports)

Pleural Effusion
(13 reports)

Hepatic Function Abnormal
(13 reports)

Hepatic Failure
(13 reports)

Aspartate Aminotransferase Increased
(13 reports)

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Isoniazid, Rifampin

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Complete drug side effects:

On eHealthMe, Isoniazid (isoniazid) is often used to treat tuberculosis. Rifampin (rifampin) is often used to treat infection. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Can you answer these questions (what is this?):

More questions for: Isoniazid, Rifampin

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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