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Review: taking Levothyroxine thyroid and Ibuprofen together

Summary: drug interactions are reported among people who take Levothyroxine thyroid and Ibuprofen together.

This review analyzes the effectiveness and drug interactions between Levothyroxine thyroid and Ibuprofen. It is created by eHealthMe based on reports of 5,734 people who take the same drugs from FDA and social media, and is updated regularly.


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On Mar, 26, 2015: 5,734 people who take Levothyroxine thyroid, Ibuprofen are studied

Levothyroxine thyroid, Ibuprofen outcomes

Drug combinations in study:
- Levothyroxine thyroid (levothyroxine sodium)
- Ibuprofen (ibuprofen)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Levothyroxine thyroid is effective0.00%
(0 of 5 people)
(2 of 10 people)
(6 of 16 people)
(9 of 21 people)
(12 of 29 people)
(21 of 33 people)
(39 of 61 people)
Ibuprofen is effective46.43%
(13 of 28 people)
(7 of 21 people)
(5 of 15 people)
(5 of 16 people)
(2 of 20 people)
(11 of 31 people)
(13 of 41 people)
(1 of 5 people)

Drug effectiveness by gender :

Levothyroxine thyroid is effective50.00%
(78 of 156 people)
(11 of 19 people)
Ibuprofen is effective31.25%
(50 of 160 people)
(7 of 17 people)

Drug effectiveness by age :

Levothyroxine thyroid is effective100.00%
(1 of 1 people)
(0 of 1 people)
(3 of 12 people)
(10 of 38 people)
(24 of 103 people)
(21 of 96 people)
(30 of 94 people)
Ibuprofen is effective0.00%
(0 of 1 people)
(1 of 1 people)
(5 of 10 people)
(7 of 38 people)
(10 of 126 people)
(18 of 114 people)
(16 of 93 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
HypotensionHeadacheDeathPainGeneral Physical Health DeteriorationPulmonary EmbolismPainPain
Oesophagitis HaemorrhagicVomitingPancreatitis AcuteInjuryUrinary Tract InfectionDeep Vein ThrombosisAnxietyNausea
DyspnoeaGastritis ErosiveRenal Failure AcuteEmotional DistressInjection Site HaemorrhagePainDeep Vein ThrombosisFatigue
VomitingDepressionHeadacheAnxietyLower Respiratory Tract InfectionAnxietyPulmonary EmbolismDyspnoea
Drug IneffectiveNauseaDeep Vein ThrombosisPulmonary EmbolismBlood Pressure DecreasedCholelithiasisEmotional DistressAnxiety
Atrial FibrillationDiarrhoeaDiarrhoeaHeadacheDysphagiaPain In ExtremityNauseaHeadache
OesophagitisDeep Vein ThrombosisAlanine Aminotransferase IncreasedAnaemiaSomnolenceNauseaDyspnoeaArthralgia
DizzinessDizzinessBlood Bilirubin IncreasedNauseaSubcutaneous HaematomaSwellingChest PainInjury
Alanine Aminotransferase IncreasedPulmonary EmbolismGastrointestinal HaemorrhageGastrointestinal HaemorrhageInternational Normalised Ratio IncreasedMobility DecreasedPalpitationsBack Pain
DiarrhoeaRashNauseaCholelithiasisAnticoagulation Drug Level Above TherapeuticImpaired Driving AbilityHot FlushVomiting

Most common drug interactions by gender * :

NauseaWeight Decreased
Drug IneffectiveRenal Failure Acute
Pain In ExtremityDyspnoea
DizzinessRespiratory Failure

Most common drug interactions by age * :

Catheter SepsisConvulsionPainPainPainPainPainNausea
Neonatal DisorderHypothyroidismPulmonary EmbolismDeep Vein ThrombosisPulmonary EmbolismNauseaNauseaFatigue
Intraventricular HaemorrhageVomitingInjuryPulmonary EmbolismFatigueAnxietyHeadachePain
Enterococcal SepsisPyrexiaAnxietyInjuryNauseaDepressionAnxietyDyspnoea
Patent Ductus ArteriosusNauseaVomitingCholecystitis ChronicAnxietyPulmonary EmbolismFatigueDrug Ineffective
Gallbladder OperationHilar LymphadenopathyCholecystitis ChronicCholelithiasisInjuryDeep Vein ThrombosisDyspnoeaFall
Sensation Of Foreign BodyChest PainDeep Vein ThrombosisAnxietyDeep Vein ThrombosisArthralgiaPain In ExtremityHypotension
Type 2 Diabetes MellitusNasal CongestionDepressionGallbladder DisorderAbdominal PainDyspnoeaArthralgiaBack Pain
Blood Cholesterol IncreasedConvulsions NosDyspepsiaAbdominal PainDyspnoeaFatigueBack PainAsthenia
Drug IneffectiveAplastic AnaemiaAffective DisorderEmotional DistressChest PainHeadacheDiarrhoeaArthralgia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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- support group for people who take Ibuprofen
- support group for people who take Levothyroxine Thyroid

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Levothyroxine Thyroid (levothyroxine sodium) is often used to treat hypothyroidism. Ibuprofen (ibuprofen) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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