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Review: Loratadine and Benadryl

This review analyzes the effectiveness and drug interactions between Loratadine and Benadryl. It is created by eHealthMe based on 1,202 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Mar, 29, 2014: 1,202 people who reported to have interactions when taking Loratadine, Benadryl are studied

Trend of Loratadine, Benadryl's drug interactions, side effects and effectiveness reports (7453465)

Drug combinations in study:
- Loratadine (loratadine)
- Benadryl (diphenhydramine hydrochloride)

eHealthMe real world results:

Most common interactions experienced by people in the use of Loratadine, Benadryl:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Dyspnoea (difficult or laboured respiration)322
Anxiety313
Vomiting269
Arthralgia (joint pain)249
Pyrexia (fever)246
Pain219
Nausea (feeling of having an urge to vomit)193
Headache (pain in head)153
Fatigue (feeling of tiredness)142
Depression131

Most common interactions experienced by people in long term use of Loratadine, Benadryl:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Short-term Memory Loss2
Anxiety2
Shortness Of Breath2
Drug Effect Decreased1
Menopausal Symptoms1
Body Temperature Fluctuation1
Pain Exacerbated1
Depression Suicidal (suicide depressive disorder)1
Dizziness1
Bone Loss1

How effective are the drugs:

not at allsomewhatmoderatehighvery high
Loratadine0.00%28.57%42.86%28.57%0.00%
Benadryl0.00%33.33%50.00%16.67%0.00%

Top conditions involved for these people * :

  1. Premedication
  2. Pain
  3. Hypersensitivity
  4. Prophylaxis
  5. Hypertension

Top co-used drugs for these people * :

  1. Claritin
  2. Seroquel
  3. Aspirin
  4. Prilosec
  5. Prednisone

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Benadryl, Loratadine

You can also:

Complete drug side effects:

On eHealthMe, Loratadine (loratadine) is often used to treat allergies. Benadryl (diphenhydramine hydrochloride) is often used to treat insomnia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (3 months ago):

  • will any these come up positive

    Reply

  • From this study (13 months ago):

  • I was on all of these and my daughter was just born a stillborn! I have had 2 previous births that were term and normal. I didn't have to take all of these with them!

    Reply

  • From this study (1 year ago):

  • Experiencing neuropathy of feet which began after gout attack -- curious if any drug interaction may be partially responsible. Note -- newest refill of Atorvastatin is manufactured by Sandoz, but have not taken any yet.

    Reply

Post a new comment    OR    Read more comments

Can you answer these questions (what is this?):

More questions for: Benadryl, Loratadine

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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