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Review: Loratadine and Benadryl

This review analyzes the effectiveness and drug interactions between Loratadine and Benadryl. It is created by eHealthMe based on reports of 1,309 people who take the same drugs from FDA and social media, and is updated regularly.

Get connected: join a mobile support group for people who take Loratadine and Benadryl >>>

What are the drugs

Loratadine (latest outcomes from 10,960 users) has active ingredients of loratadine. It is often used in allergies.

Benadryl (latest outcomes from 29,335 users) has active ingredients of diphenhydramine hydrochloride. It is often used in allergies.

On Sep, 27, 2014: 1,309 people who take Loratadine, Benadryl are studied

Loratadine, Benadryl outcomes

Drug combinations in study:
- Loratadine (loratadine)
- Benadryl (diphenhydramine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Loratadine is effective17.65%
(3 of 17 people)
25.00%
(3 of 12 people)
14.29%
(1 of 7 people)
33.33%
(3 of 9 people)
55.56%
(5 of 9 people)
33.33%
(3 of 9 people)
0.00%
(0 of 1 people)
0.00%
(0 of 1 people)
Benadryl is effective42.86%
(9 of 21 people)
46.15%
(6 of 13 people)
33.33%
(1 of 3 people)
60.00%
(3 of 5 people)
50.00%
(4 of 8 people)
50.00%
(4 of 8 people)
0.00%
(0 of 1 people)
0.00%
(0 of 2 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DizzinessAcute Respiratory Distress SyndromeDemyelinationEosinophilic PneumoniaFatigueShort-term Memory LossShoulder PainNausea
HypotensionSmall Intestinal ObstructionLeukopeniaBone LossDrowsinessMenopausal SymptomsShort-term Memory LossPain
VomitingDisseminated Intravascular CoagulationPremature LabourBladder IrritationDrug Effect DecreasedRespiratory ArrestMenopausal SymptomsDyspnoea
BronchitisPneumonia Respiratory Syncytial ViralDyspepsiaRespiratory ArrestAsthmaDeathHeadache
AgranulocytosisPost Procedural HaemorrhageDehydrationDeathGynaecomastiaDizzinessFatigue
ConvulsionHypotensionSystemic Inflammatory Response SyndromeBody Temperature FluctuationShortness Of BreathDepression
ThrombocytopeniaHypernatraemiaGastrooesophageal Reflux DiseasePain ExacerbatedAsthmaArthralgia
Pneumonia Respiratory Syncytial ViralBlood Bilirubin IncreasedAnxietyAcid RefluxBody Temperature FluctuationVomiting
Myocardial InfarctionPneumonitisH1n1 InfluenzaChest PainPain ExacerbatedPyrexia
Blood Pressure IncreasedBronchitisCrohn's DiseaseHeadacheRashAnxiety

Drug effectiveness by gender :

FemaleMale
Loratadine is effective26.83%
(11 of 41 people)
29.17%
(7 of 24 people)
Benadryl is effective37.50%
(15 of 40 people)
57.14%
(12 of 21 people)

Most common drug interactions by gender * :

FemaleMale
NauseaNausea
PainVomiting
HeadacheDyspnoea
ArthralgiaPyrexia
DyspnoeaRash
DepressionFatigue
FatigueCough
AnxietyDizziness
Pain In ExtremityHeadache
Oedema PeripheralPain Nos

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Loratadine is effectiven/a50.00%
(2 of 4 people)
20.00%
(1 of 5 people)
4.76%
(1 of 21 people)
23.81%
(5 of 21 people)
17.39%
(4 of 23 people)
21.43%
(3 of 14 people)
8.70%
(2 of 23 people)
Benadryl is effectiven/a66.67%
(2 of 3 people)
66.67%
(4 of 6 people)
33.33%
(7 of 21 people)
10.00%
(2 of 20 people)
36.84%
(7 of 19 people)
21.43%
(3 of 14 people)
9.09%
(2 of 22 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
AggressionVomitingHeadacheCerebral HaemorrhageFallPainNauseaNausea
ConvulsionCoughPneumonitisConvulsionBronchitisNauseaChest PainAsthenia
Hyperkinetic SyndromeStatus EpilepticusHypotensionCerebral InfarctionDepressionDyspnoeaOedema PeripheralDyspnoea
Abdominal Pain NosHeart Rate IncreasedAcute Respiratory Distress SyndromeTransverse Sinus ThrombosisObesityArthralgiaDiarrhoeaFatigue
Tardive DyskinesiaNauseaFatigueLoss Of ConsciousnessBlood Cholesterol IncreasedVomitingPainDizziness
MydriasisSinusitisBlood Bilirubin IncreasedPainArthralgiaFatigueHeadacheCardiac Failure Congestive
NervousnessRespiratory Tract InfectionPyrexiaBlood Pressure IncreasedContusionBack PainPain In ExtremityVomiting
Drug IneffectiveHeadacheNauseaPyrexiaJoint SwellingAnxietyAnxietyDiarrhoea
ConstipationDrug IneffectiveLymphadenopathyNauseaAnaemiaHeadacheDyspnoeaDrug Ineffective
Foaming At MouthHilar LymphadenopathyPainCognitive DisorderAbdominal PainDepressionRashMyalgia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Loratadine and Benadryl?

Get connected! Join a related mobile support group:
- support group for people who take Loratadine and Benadryl
- support group for people who take Benadryl
- support group for people who take Loratadine

Comments from related studies:

  • From this study (10 months ago):

  • will any these come up positive

    Reply

  • From this study (2 years ago):

  • I was on all of these and my daughter was just born a stillborn! I have had 2 previous births that were term and normal. I didn't have to take all of these with them!

    Reply

  • From this study (2 years ago):

  • Experiencing neuropathy of feet which began after gout attack -- curious if any drug interaction may be partially responsible. Note -- newest refill of Atorvastatin is manufactured by Sandoz, but have not taken any yet.

    Reply

Post a new comment    OR    Read more comments

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Complete drug side effects:

On eHealthMe, Loratadine (loratadine) is often used to treat allergies. Benadryl (diphenhydramine hydrochloride) is often used to treat allergies. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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