Review: Lunesta and Benadryl drug interactions
This review analyzes the interactions between Lunesta and Benadryl. It is created by eHealthMe based on 276 people who have drug interactions while taking the drugs. The review uses reports from FDA and social media, and is updated regularly.
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What are the drugs
Lunesta (latest outcomes from 16,147 users) has active ingredients of eszopiclone. It is often used in insomnia.
Benadryl (latest outcomes from 29,259 users) has active ingredients of diphenhydramine hydrochloride. It is often used in allergies.
On Mar, 10, 2014: 276 people who reported to have interactions when taking Lunesta, Benadryl are studied
Drug combinations in study:
- Lunesta (eszopiclone)
- Benadryl (diphenhydramine hydrochloride)
Most common interactions experienced by people in the use of Lunesta, Benadryl:(click on each outcome to view in-depth analysis, incl. how people recovered)
|Interaction||Number of reports|
|Dyspnoea (difficult or laboured respiration)||122|
|Osteonecrosis Of Jaw (death of bone of jaw)||70|
|Nausea (feeling of having an urge to vomit)||63|
|Metastases To Bone (cancer spreads to bone)||52|
|Gastrooesophageal Reflux Disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)||49|
|Pain In Extremity||48|
Most common interactions experienced by people in long term use of Lunesta, Benadryl:(click on each outcome to view in-depth analysis, incl. how people recovered)
|Interaction||Number of reports|
|Post Procedural Bile Leak||2|
|Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)||2|
|Abdominal Abscess (collection of pus in abdomen)||2|
|Ventricular Septal Defect (a hole in the heart, is a common heart defect that's present at birth (congenital))||2|
|Cardiac Failure Congestive||2|
|Congenital Cardiovascular Anomaly (birth defect of heart vessels)||2|
|Drug Exposure During Pregnancy||2|
|Pleural Effusion (water on the lungs)||2|
|Cardiomegaly (increased size of heart than normal)||2|
How effective are the drugs:
|not at all||somewhat||moderate||high||very high|
Top conditions involved for these people * :
Top co-used drugs for these people * :
- Diphenhydramine hcl
* Approximation only. Some reports may have incomplete information.
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Complete drug side effects:
On eHealthMe, Lunesta (eszopiclone) is often used to treat insomnia. Benadryl (diphenhydramine hydrochloride) is often used to treat allergies. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.
What is the drug used for and how effective is it:
- Lunesta is used in:
- Benadryl is used in:
Other drugs that are used to treat the same conditions:
- Lunesta alternatives:
- Benadryl alternatives:
Comments from related studies:
From this study (2 years ago):
From this study (2 years ago):
I have rheumatoid since feb 2010 and having tried multiple meds and shots with no improvement. Decided to try Dandelion with much sucess, but last 2 months have been having gross edema to extremeties and trunk. started Keflex for infected eye glad and by 10:30 pm went to ER for atrial fibrillation. Sent home on Metoprolo, aspirin, and augmentin. Worsening edem to hands, trunk and pitting edema to legs. Not sure what is causing it. have gained at least 15 lbs in a 2 week perion.
I a having swelling around my nipples (I'm not pregnant) and just recently increased my lamactal dosage by 1/2. Could this possibly be a side effect?
Can you answer these questions (what is this?):
- By Cuervo: What forms of pain management are there for torn rotator cuff?
This is a ten year old injury, my first MRI was in 2005, didn't find anything significant. November 2013 2nd MRI shows significant tear as well as bursitis? My Dr really hasn't tried to manage the pain.
- By Krisleigh: How do you know for sure benadryl caused the hair loss
I'm 36 years old and have been taking Benadryl to help sleep for 6-8 months, 4-5 nights a week. The past couple months I've noticed a ton of shedding especially around my crown towards the mid to back of my part and now see my scalp through the hair that is still there. I'm starting to panic and ha ...
- By Mia: Can i take saphris with sudafed and benadryl
Is it ok to take sudafed and Benadryl cold and flu tablets with saphris bipolar tablets?
You may be interested at these reviews (what is this?):
- By snoozy: Zopiclone causing sweating and memory loss
Been on 10mg Zopivane for probably 5 - 10 years. In 2013 migrated to 15mg Zopiclone. Previously experienced hot flashes 3 times a week and in 2013 has increased to 3 to 5 times a night. Usually I have 3 hours sleep, then after midnight the flashed start. In the morning there are sopping wet clothe ...
- By Jillie: Leg pain and occasional arm and hand pain
I started having leg pains at night, lower leg felt like the muscle and bone were being pulled causing sharp pain. It was relieved by getting up and walking but would last most of the night. I finally realized after suffering this over and over for months, that it only happened when I had taken be ...
Recent related drug studies:
- A study of drug interactions between Omeprazole, Benadryl, Lunesta, Dandelion Herb, L-Ornithine, Ginger Root, Petroselinum Crispum for a patient with Gastric Disorder, Insomnia, Rheumatoid Arthritis, Kidney Failure. The patient has Kelp, Amoxicillin And Clavulanate Potassium, Metoprolol Succinate, Aspiration
- A study of drug interactions between Amitriptyline Hydrochloride, Amitriptyline Hydrochloride, Topamax, Topamax, Lyrica, Lamictal - 200MG, Lunesta, Abilify, Vitamin D, Benadryl for a patient with Sleep Disorder, Mood Stabilizer, Low Vitamin Level, Help For Sleep.
NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
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