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Review: Lunesta and Benadryl

This review analyzes the effectiveness and drug interactions between Lunesta and Benadryl. It is created by eHealthMe based on reports of 308 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: join a mobile support group for people who take Lunesta and Benadryl >>>

What are the drugs

Lunesta (latest outcomes from 16,168 users) has active ingredients of eszopiclone. It is often used in insomnia.

Benadryl (latest outcomes from 29,318 users) has active ingredients of diphenhydramine hydrochloride. It is often used in allergies.

On Jul, 14, 2014: 308 people who take Lunesta, Benadryl are studied

Lunesta, Benadryl outcomes

Drug combinations in study:
- Lunesta (eszopiclone)
- Benadryl (diphenhydramine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Lunesta is effective20.00%
(1 of 5 people)
0.00%
(0 of 3 people)
0.00%
(0 of 1 people)
25.00%
(2 of 8 people)
50.00%
(1 of 2 people)
100.00%
(3 of 3 people)
n/an/a
Benadryl is effective16.67%
(1 of 6 people)
0.00%
(0 of 5 people)
50.00%
(1 of 2 people)
n/a0.00%
(0 of 1 people)
75.00%
(3 of 4 people)
100.00%
(1 of 1 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DysgeusiaInsomniaInsomniaCardiac Failure CongestiveUrticariaConvulsionAngerPain
Drug IneffectiveDysgeusiaAtrial Septal DefectPruritusPyrexiaSweating - ExcessiveWeight Decreased
InsomniaUrticariaCongenital Cardiovascular AnomalyAbdominal AbscessIrritabilityNausea
DyspnoeaCardiomegalyPost Procedural Bile LeakPanic AttackOsteonecrosis Of Jaw
NauseaDrug Exposure During PregnancyAnorgasmiaNystagmusDyspnoea
VomitingPleural EffusionAnxietyInsomnia
PneumoniaVentricular Septal DefectDizzinessPain In Extremity
Initial InsomniaTinnitusArthralgia
Multiple Drug OverdoseTongue DisorderAnxiety
FatigueDrug HypersensitivityConstipation

Drug effectiveness by gender :

FemaleMale
Lunesta is effective25.00%
(4 of 16 people)
50.00%
(3 of 6 people)
Benadryl is effective35.71%
(5 of 14 people)
20.00%
(1 of 5 people)

Most common drug interactions by gender * :

FemaleMale
PainPneumonia
Weight DecreasedOsteonecrosis Of Jaw
NauseaWeight Decreased
DyspnoeaAnaemia
InsomniaOsteopenia
ArthralgiaBone Disorder
Metastases To BoneAnxiety
FatigueCompression Fracture
Osteonecrosis Of JawHepatic Steatosis
ConstipationDepression

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Lunesta is effectiven/an/an/a0.00%
(0 of 5 people)
18.18%
(2 of 11 people)
50.00%
(4 of 8 people)
0.00%
(0 of 7 people)
50.00%
(1 of 2 people)
Benadryl is effectiven/an/an/a25.00%
(1 of 4 people)
22.22%
(2 of 9 people)
25.00%
(2 of 8 people)
14.29%
(1 of 7 people)
0.00%
(0 of 2 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/aSuicide AttemptVomitingExcoriationBack PainInsomniaPneumonia
Abdominal Pain UpperInsomniaThrombophlebitis SuperficialIntervertebral Disc ProtrusionNauseaWeight Decreased
PancreatitisPalpitationsConvulsionPainPainFatigue
Abdominal PainNauseaHaemoglobin DecreasedDepressionPain In ExtremityFall
SomnolenceBack PainErectile DysfunctionAnxietyFatigueArthralgia
Initial InsomniaAstheniaFlushingPain In ExtremityAnaemiaHyponatraemia
DiarrhoeaLeft Ventricular HypertrophyConstipationDyspnoeaNausea
Abdominal PainDrug Screen PositiveOsteonecrosis Of JawHypoaesthesiaOsteoarthritis
PresyncopeDrug AbuseBone DisorderWeight DecreasedPain
OverdoseImpaired HealingSpinal OsteoarthritisGait DisturbancePulmonary Hypertension

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group:
- group for people who take Lunesta and Benadryl
- group for people who take Benadryl
- group for people who take Lunesta

Comments from related studies:

  • From this study (4 weeks ago):

  • Itching in extremeties with no rash apparent. Eyes watery and burning. Twitching is in left eyelid. Itching started 8 days ago. Lotion does not help much. Diphenhydramine does not help much.

    Reply

  • From this study (2 years ago):

  • I have rheumatoid since feb 2010 and having tried multiple meds and shots with no improvement. Decided to try Dandelion with much sucess, but last 2 months have been having gross edema to extremeties and trunk. started Keflex for infected eye glad and by 10:30 pm went to ER for atrial fibrillation. Sent home on Metoprolo, aspirin, and augmentin. Worsening edem to hands, trunk and pitting edema to legs. Not sure what is causing it. have gained at least 15 lbs in a 2 week perion.

    Reply

  • From this study (2 years ago):

  • I a having swelling around my nipples (I'm not pregnant) and just recently increased my lamactal dosage by 1/2. Could this possibly be a side effect?

    Reply

Post a new comment    OR    Read more comments

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More reviews for: Benadryl, Lunesta

Complete drug side effects:

On eHealthMe, Lunesta (eszopiclone) is often used to treat insomnia. Benadryl (diphenhydramine hydrochloride) is often used to treat allergies. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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