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Review: taking Macrobid and Pepcid Ac together

Summary: drug interactions are reported among people who take Macrobid and Pepcid Ac together.

This review analyzes the effectiveness and drug interactions between Macrobid and Pepcid Ac. It is created by eHealthMe based on reports of 140 people who take the same drugs from FDA and social media, and is updated regularly.





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What are the drugs

Macrobid has active ingredients of nitrofurantoin; nitrofurantoin, macrocrystalline. It is often used in urinary tract infection. (latest outcomes from 3,450 Macrobid users)

Pepcid Ac has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. (latest outcomes from 3,317 Pepcid Ac users)

On Feb, 25, 2015: 140 people who take Macrobid, Pepcid Ac are studied

Macrobid, Pepcid Ac outcomes

Drug combinations in study:
- Macrobid (nitrofurantoin; nitrofurantoin, macrocrystalline)
- Pepcid Ac (famotidine)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Macrobid is effectiven/an/a0.00%
(0 of 1 people)
Pepcid Ac is effectiven/an/a50.00%
(1 of 2 people)

Drug effectiveness by gender :

Macrobid is effective0.00%
(0 of 1 people)
Pepcid Ac is effective50.00%
(1 of 2 people)

Drug effectiveness by age :

Macrobid is effectiven/an/an/an/an/an/an/a0.00%
(0 of 3 people)
Pepcid Ac is effectiven/an/an/an/a0.00%
(0 of 1 people)
(1 of 3 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Mobility DecreasedSwellingDepressionMyocardial InfarctionOvarian Cystn/an/aPain
FatigueExhaustion, Fatigue, Lethargy, Tiredness, WearinessHypertensive Heart DiseasePain In ExtremityArthralgia
Fat Tissue IncreasedHallucination, VisualNervous System DisorderDyspnoeaFatigue
Ocular HyperaemiaPulmonary FibrosisOedema PeripheralNausea
PruritusSkin CancerSickle Cell Anaemia With CrisisGait Disturbance
Weight IncreasedHypertensionChest PainFall
Swelling FaceGastrooesophageal Reflux DiseaseCarpal Tunnel SyndromeBack Pain
RashBunionPulmonary EmbolismUrinary Tract Infection
Eye SwellingChronic Obstructive Pulmonary DiseaseInfectionDizziness
Heart Rate IncreasedConstipationDyspnoea

Most common drug interactions by gender * :

Gait DisturbanceDecreased Appetite
NauseaGastrooesophageal Reflux Disease
Back PainHypokalaemia
Urinary Tract InfectionFatigue
Tardive DyskinesiaRenal Failure Acute

Most common drug interactions by age * :

n/an/aAbdominal Pain LowerAbdominal Pain UpperHaemorrhoidsPainMyocardial InfarctionGait Disturbance
PollakiuriaCholelithiasisHypotoniaDyspnoeaGroin PainPain
Abdominal PainDeep Vein ThrombosisMean Cell Haemoglobin Concentration DecreasedOedema PeripheralHeart Rate IncreasedTardive Dyskinesia
Gallbladder DisorderPremature BabyHaemoglobin DecreasedFatigueBreast DisorderDizziness
Abdominal Pain UpperPremature Separation Of PlacentaHaematocrit DecreasedDepressionDyspnoeaFall
Urinary Tract InfectionComplications Of Maternal Exposure To Therapeutic DrugsElectrocardiogram Abnormal NosArthralgiaCerebrovascular AccidentUrinary Tract Infection
Bile Duct StoneMaternal Drugs Affecting FoetusFallAnxietyChest PainDysphagia
EnuresisNephrolithiasisFeeling Hot And ColdEmotional DistressUrethral StenosisFatigue
PancreatitisCholecystitis ChronicMenstruation IrregularBack PainSialoadenitisArthralgia
Vaginal DischargePancreatitisMuscle Contractions InvoluntaryGastrooesophageal Reflux DiseaseAstheniaVomiting

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Macrobid and Pepcid Ac?

You are not alone! Join a related mobile support group:
- support group for people who take Macrobid and Pepcid Ac
- support group for people who take Macrobid
- support group for people who take Pepcid Ac

Can you answer these questions (Ask a question):

More questions for: Macrobid, Pepcid Ac

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More reviews for: Macrobid, Pepcid Ac

Complete drug side effects:

On eHealthMe, Macrobid (nitrofurantoin; nitrofurantoin, macrocrystalline) is often used to treat urinary tract infection. Pepcid Ac (famotidine) is often used to treat gastroesophageal reflux disease. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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