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Review: Macrobid and Pepcid Ac

This review analyzes the effectiveness and drug interactions between Macrobid and Pepcid Ac. It is created by eHealthMe based on 138 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

On Apr, 1, 2014: 138 people who reported to have interactions when taking Macrobid, Pepcid Ac are studied

Trend of Macrobid, Pepcid Ac's drug interactions, side effects and effectiveness reports (3298393)

Drug combinations in study:
- Macrobid (nitrofurantoin; nitrofurantoin, macrocrystalline)
- Pepcid Ac (famotidine)

eHealthMe real world results:

Most common interactions experienced by people in the use of Macrobid, Pepcid Ac:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Arthralgia (joint pain)123
Dyspnoea (difficult or laboured respiration)95
Fatigue (feeling of tiredness)85
Nausea (feeling of having an urge to vomit)80
Urinary Tract Infection67
Gait Disturbance58

Most common interactions experienced by people in long term use of Macrobid, Pepcid Ac:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Dyspnoea (difficult or laboured respiration)2
Ovarian Cyst (fluid filled sac of the ovary)2
Carpal Tunnel Syndrome (nerve compression at wrist results numbness weakness, pain , swelling)2
Chest Pain2
Skin Cancer2
Sickle Cell Anaemia With Crisis (sickle cell anaemia have painful episodes)2
Pain In Extremity2
Oedema Peripheral (superficial swelling)2
Pulmonary Embolism (blockage of the main artery of the lung)2

How effective are the drugs:

not at allsomewhatmoderatehighvery high
Pepcid Ac0.00%0.00%0.00%100.00%0.00%

Top conditions involved for these people * :

  1. Gastrooesophageal reflux disease
  2. Pain
  3. Rhinitis allergic
  4. Rheumatoid arthritis
  5. Depression

Top co-used drugs for these people * :

  1. Premarin
  2. Prednisone tab
  3. Levaquin
  4. Prilosec
  5. Nexium

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Macrobid, Pepcid Ac

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Complete drug side effects:

On eHealthMe, Macrobid (nitrofurantoin; nitrofurantoin, macrocrystalline) is often used to treat urinary tract infection. Pepcid Ac (famotidine) is often used to treat gastroesophageal reflux disease. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Can you answer these questions (what is this?):

More questions for: Macrobid, Pepcid Ac

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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