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Review: taking Meclizine and Promethazine together

Summary: drug interactions are reported among people who take Meclizine and Promethazine together.

This review analyzes the effectiveness and drug interactions between Meclizine and Promethazine. It is created by eHealthMe based on reports of 359 people who take the same drugs from FDA and social media, and is updated regularly.





You are not alone: join a mobile support group for people who take Meclizine and Promethazine >>>

What are the drugs

Meclizine has active ingredients of meclizine hydrochloride. It is often used in dizziness. (latest outcomes from 5,834 Meclizine users)

Promethazine has active ingredients of promethazine hydrochloride. It is often used in nausea. (latest outcomes from 1,218 Promethazine users)

On Feb, 24, 2015: 359 people who take Meclizine, Promethazine are studied

Meclizine, Promethazine outcomes

Drug combinations in study:
- Meclizine (meclizine hydrochloride)
- Promethazine (promethazine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Meclizine is effective50.00%
(1 of 2 people)
(0 of 1 people)
(0 of 2 people)
(1 of 1 people)
(0 of 1 people)
(0 of 1 people)
Promethazine is effective66.67%
(2 of 3 people)
(0 of 2 people)
(1 of 2 people)
(1 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Itchingn/aDizzinessn/an/aNumbness And Tinglingn/aNausea
Burning SensationMood SwingsVomiting
Sleeping DifficultyShort-term Memory LossPain
Premenstrual SyndromeDizziness
Polycystic OvariesChest Pain
Thinking SlowedAbdominal Pain
Metabolic DisorderHeadache
Night SweatsAnxiety
Aggression AggravatedVertigo

Drug effectiveness by gender :

Meclizine is effective25.00%
(2 of 8 people)
Promethazine is effective50.00%
(4 of 8 people)

Most common drug interactions by gender * :

AnxietyChest Pain
Abdominal PainVertigo
Oedema PeripheralRash
Back PainHeadache

Drug effectiveness by age :

Meclizine is effectiven/an/an/a0.00%
(0 of 25 people)
(1 of 5 people)
(0 of 1 people)
(1 of 2 people)
Promethazine is effectiven/an/an/a0.00%
(0 of 25 people)
(2 of 5 people)
(1 of 1 people)
(1 of 2 people)

Most common drug interactions by age * :

Decreased Appetiten/aPainCompleted SuicideDizzinessPainCardiogenic ShockAsthenia
SwellingPulmonary EmbolismPainVomitingConstipationVomitingOedema Peripheral
Weight DecreasedEructationAbdominal PainVertigoNauseaPainAbdominal Pain
Helicobacter GastritisCholecystitis ChronicHeadacheHypoaesthesiaDizzinessNausea
HeadacheInjuryNauseaAnxietyCardiac Failure CongestiveAnxiety
LabyrinthitisBiliary DyskinesiaAbdominal PainWeight DecreasedHepatic FailureBack Pain
TremorNauseaDepressionRashRenal Failure AcuteHeadache
HaemorrhoidsMuscular WeaknessFatigueParaesthesiaDeep Vein ThrombosisFall
Postural Orthostatic Tachycardia SyndromeHypoaesthesiaChest PainTremorSeptic ShockVomiting
Hepatic SteatosisPeripheral ColdnessNight SweatsDyspnoeaAzotaemiaDyspnoea

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of Meclizine and Promethazine on

Do you take Meclizine and Promethazine?

You are not alone! Join a related mobile support group:
- support group for people who take Meclizine and Promethazine
- support group for people who take Meclizine
- support group for people who take Promethazine

Can you answer these questions (Ask a question):

More questions for: Meclizine, Promethazine

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More reviews for: Meclizine, Promethazine

Comments from related studies:

  • From this study (2 years ago):

  • I started having seizures about 9 months ago. Each time the seizures are more violent and last longer.


  • From this study (3 years ago):

  • Do any of these drugs interact to cause defiancy? also which ones would most likely make someone hallucinate? Thank you.


  • From this study (5 years ago):

  • I am on SS Disability since 2005 for acute back pain ,joint pain,migraines and depression. I have Fibromyligia and have suffered every day for 31 years. Pain began during my first pregancy in 1978.I have had many surgeries and shots for pain.Having more surgery starting tomorrow with another carpel tunnel surgery followed soon by two back surgies I have needed for many years without being able too afford. I am now on Medicade and medicare.


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Complete drug side effects:

On eHealthMe, Meclizine (meclizine hydrochloride) is often used to treat dizziness. Promethazine (promethazine hydrochloride) is often used to treat nausea. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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