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Review: Methadone and Vyvanse





Summary: drug interactions are reported among people who take Methadone and Vyvanse together.

This review analyzes the effectiveness and drug interactions between Methadone and Vyvanse. It is created by eHealthMe based on reports of 22 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Methadone and Vyvanse >>>

What are the drugs

Methadone Hydrochloride has active ingredients of methadone hydrochloride. It is often used in pain. (latest outcomes from Methadone Hydrochloride 2,835 users)

Vyvanse has active ingredients of lisdexamfetamine dimesylate. It is often used in attention deficit hyperactivity disorder. (latest outcomes from Vyvanse 7,831 users)

On Nov, 26, 2014: 22 people who take Methadone Hydrochloride, Vyvanse are studied

Methadone Hydrochloride, Vyvanse outcomes

Drug combinations in study:
- Methadone Hydrochloride (methadone hydrochloride)
- Vyvanse (lisdexamfetamine dimesylate)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Methadone Hydrochloride is effectiven/an/a0.00%
(0 of 2 people)
66.67%
(2 of 3 people)
100.00%
(2 of 2 people)
100.00%
(1 of 1 people)
0.00%
(0 of 2 people)
n/a
Vyvanse is effective0.00%
(0 of 1 people)
100.00%
(1 of 1 people)
0.00%
(0 of 3 people)
0.00%
(0 of 1 people)
n/a100.00%
(1 of 1 people)
n/a100.00%
(1 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Logorrhoean/aMuscle TwitchingWithdrawal Syndromen/aWithdrawal Bleedn/aDrug Ineffective
HyperhidrosisSleep TalkingDry EyeSomnolence
DyspnoeaSweating IncreasedDeath SuddenDisturbance In Attention
NauseaCold SweatHeat StrokeListless
PalpitationsDisorientationMusculoskeletal PainDrug Hypersensitivity
Drug HypersensitivityWeight GainFlight Of Ideas
TremorHypertensionDrug Effect Decreased
Psychomotor HyperactivityChest PainAnger
Disturbance In AttentionApathy
ChillsInfluenza Like Illness

Drug effectiveness by gender :

FemaleMale
Methadone Hydrochloride is effective66.67%
(2 of 3 people)
42.86%
(3 of 7 people)
Vyvanse is effective50.00%
(1 of 2 people)
33.33%
(2 of 6 people)

Most common drug interactions by gender * :

FemaleMale
Drug IneffectiveDrug Withdrawal Syndrome
Disturbance In AttentionMuscle Twitching
AngerSleep Talking
StressFeeling Abnormal
TremorOverdose
PalpitationsDrug Hypersensitivity
Psychomotor HyperactivitySomnolence
Drug Effect DecreasedSweating Increased
ListlessCold Sweat
FatigueDisorientation

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Methadone Hydrochloride is effectiven/an/an/a50.00%
(1 of 2 people)
20.00%
(3 of 15 people)
11.11%
(1 of 9 people)
0.00%
(0 of 1 people)
n/a
Vyvanse is effectiven/an/an/a50.00%
(1 of 2 people)
0.00%
(0 of 13 people)
11.11%
(1 of 9 people)
100.00%
(1 of 1 people)
n/a

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/an/aDrug HypersensitivityDisorientationDisturbance In AttentionSomnolencen/a
Dry EyeAngerDrug Ineffective
Cold SweatDrug Effect DecreasedPsychomotor Hyperactivity
Sweating IncreasedFlight Of IdeasPalpitations
Muscle TwitchingListlessNausea
Sleep TalkingStressTremor
Withdrawal BleedApathy
Death SuddenMyalgia
Musculoskeletal PainInfluenza Like Illness
Chest PainLogorrhoea

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Methadone and Vyvanse?

You are not alone! Join a related mobile support group:
- support group for people who take Methadone and Vyvanse
- support group for people who take Methadone Hydrochloride
- support group for people who take Vyvanse

Can you answer these questions (Ask a question):

  • I have been told by my gastroenterologist that i have gastroparesis, what are my treatment options, if any?
    I've had a CT scan and a Gastric Emptying study completed. My stomach is only 35% emptied after 4 hours, it should be at least 90% empty at that point. I have a colonoscopy and esophagealendoscopy scheduled for the first week of the year. What are my treatment options at this point?
  • Any experience or studies of vyvance (lisdexamfetamine) causing vit b12 absorbsion issues and ultimately deficiency? (2 answers)
    Taking Vyvance for about 12 months and just been diagnosed with Pernicious Anaemia and Vit B12 deficiency. Symptoms triggering B12/Intrisic factor tests was extreme fatigue and foul mood during a menstrual cycle.
    Looking to see if anyone else has a similar issue or any knowledge of Vyvance causing any issue with absorption by either altering the bacteria or proteins in the stomach.
    I've had the loading dose of 6 B12 jags (every 2 days) the last a week ago and although I pick up a bit in the evening I am still exhausted in the morning and most of the day. Thanks
  • Can long-term methadone use cause or increase the risk of colon cancer?
    I had a two-level spinal fusion at L4-S1 in 2000 after being injuried at work in Sept. 24, 1997. I lost everything after...the unjury, ability to do my job, my wife and family (couldn't take the strain) my home, my sense of self and purpose, direction and belonging...credit rating and ability to pay my bills.
    After a long period of waiting to settle my workmens' comp. case, I returned home, from the Bat Area back to Arizona to take of my mother with a yet un dianosed case of moderate dementia.
    Then, in 2011 I had a 2nd surgery to relieve spinal stenosis btwn. L2-L4, just above the fusion site.
    I've been taking methadone since early 2004, a little over ten years, now. I've had high blood pressure since my injury.

    Now, I waiting to be scheduled for a colonoscopy, with my father having had polyps and the way I've been feeling..drained, tired all the time, and stomach pains ( in addition to my chronic low back pain), I...
    find myself wondering if there is any relationtionship between the methadone and other meds and cancer?
  • Is the water clear or cloudy when you dissolve vyvanse and is there a way to tell if the powder in the capsule is real
    When I have dissolved my 70 mg vyvanse in water it is usually clear but now it is cloudy. which should it be cloudy or clear. I feel like someone is changing the powder in my capsules. Is there a way to tell if its the real powder in the capsule.
  • Is it safe to take unisom on top of vyvanse
    I have took 5 ritalin 20mg and 2 30 mg vyvanse since early this morning. It is now 1:00in the morning, I'm very tired. I have 2 toddlers that I have to take carevof. Just wanting to know if it is ok to take some unison now so I can get some sleep

More questions for: Methadone Hydrochloride, Vyvanse

You may be interested at these reviews (Write a review):

  • 3 strong drugs together against neuropathic pain
    Neuropathic pain debuted when I was 24, now I'm 50. Received diagnosed with Ehler-Danlos syndrome (EDS), joint hypermobility type, when I was 35 years old. So it can take some time to get a diagnose. And as EDS-patient I do not belong to any clinic. Orthopedics says that EDS is not orthopedic, rheumatology says that EDS is not an autoimmune disease, GPs say that EDS is too difficult, and so on. Sooner or later we all end up at Psychiatry, even if we are not depressed.

    The first kind of pain I got when I was 24 came from low back, but I experienced as pelvic pain and leg pain. It was clearly a neuropathic pain, but it took years to find out. Later it was treated by a pain clinic with cortisone around the genitofemoral nerves (both sides). Since this treatment didn't result in lasting freedom from pain, the pain clinic started to give me RF (radio frequency) treatment. This made the pain disappeared after one year, and I was 80% free from it between 2002 and 2014, 12 years. The pain doctors said pain could return after 10 years.

    The other kind of neuropathic pain started 2003 with intense stomach pain. During 6 months I could hardly eat nothing due to nausea and vomiting. After this 6 months, stomach pain changed to almost unbearable pain in upper back.
    What happened 2003, and what all the doctors missed, was that the right lowest ribs slid up over the sternum. This rib dislocation is till there today, but now with a lot of cartilage formed around the rib where it is stuck in the lower end of the sternum. The dislocation is clearly visible on X-ray. This has greatly affected the thoracic spine. I have a scoliosis which I had not before 2003. And I still have severe pain in the thoracic spine.

    It was initially treated with morphine daily, and later with Durogesic (fentanyl), but this didn't help much. 2005 I was hospitalized because I had too much pain to take care of myself and my hygiene. After some months the doctors started to give me clonazepam because the muscles along the spine was in a chronic seizures. Clonazepam helped, but I could still have a lot of pain in two vertebrae in the thoracic spine. It felt as if someone drilled into the vertebrae without anesthesia. After a few months, doctors also prescribed me methadone. Then the pain disappeared almost completely. Since 2006, I have eaten clonazepam and methadone every day, and I need to sleep in an armchair to not get more pain because of moving during sleep.

    There are side effects. After 1,5 years with clonazepam and methadone I started to have panic attacks. Or rather one long panic attack which didn't stop before I got treatment with amitryptilin and pregabalin (Lyrica). These 2 medicines stopped the panic disorder completely after some hours, and the panic was then gone. Then I got side effects of these 2 medicines, amitryptilin & Lyrica, too. I gained a lot of weight (from 83 to 148 kg) and got much water (edema) in both my legs under the knees and in both feet. The feet could swallow to the double size. 2012 I stopped with amitryptilin and started to loose weight again (in Aug 2014 below 80 kg) and get less water in my legs. Today I eat as little medicines I can, but I have to take methadone, clonazepam and Lyrica every day, twice. If I try to take away one of these 3 medicines, I got pain problems at once. Lyrica is the most painful one to take away. In Sept-Dec 2013 I lowered Lyrica from 300 mg daily, to 150, then to 75 and finally 0 mg. The pain I had was extremely difficult to handle. It didn't help to take more methadone or anything else. I have checked on Internet and found that many people got pain from quitting with Lyrica. Most people start eating it again. So did I. But 2006 and 2007 it was enough to treat the pain with methadone and clonazepam, I got the Lyrica against anxiety not pain. But today I take Lyrica against pain.

    Beside weight gain and leg edema, clonazepam and Lyrica significantly affect the sexual desire. And Lyrica alone makes it almost impossible to ejaculate. All four drugs together (clonazepam, methadone, amitryptiline and Lyrica), make one forget all about sex life. You don't even miss it. When I stopped with amitryptiline and lowered Lyrica (still taking clonazepam and methadone), I could suddenly easily get erections again, feel desire, but not getting orgasms. This is quite difficult to deal with.

    The pain pattern is greatly affected, by pain and by the medicines. So is the mood. I get something which feels like heavy depression, especially if I take the medicines late that day. I should take a medicine like methadone 3 times a day, because the effects of the tablet lasts around 8 hours. But I take them every 12 hours, to have a low consumption in case doctors prescribe them too late (which happens, and then it's good to have a spouse going to the pharmacy buying them for you, because you have too much pain to go yourself).

    Since methadone is also used for treating heroine addicts, medical staff treat you with disrespect when they see that it says "methadone" in your health record. I need to show a certificate that says that I deal with chronic neuropathic pain, that I never have had problems with drug addiction, to get normal respect.

    I wanted to share this because I think I am alone in the world with these medicines in combination against neuropathic pain caused by hypermobile joints, joint dislocation and muscle spasms. After trying almost everything else, including surgery cutting nerves, methadone, clonazepam and Lyrica seems to be the only way to kill my pain. But it's a life where you always is questioned, because of the use of methadone. I can guarantee that everybody in the world should accept these medicines if they had experienced the unbearable pain I had in upper back before they started to give me clonazepam and methadone.
  • Nexium improves my constipation
    Started taking Nexium 1 week ago and I noticed improvement with my chronic constipation.
  • Xanax bed wetting will it stop and do i wear diapers or die (1 response)
    I am on the very edge of crazy. So starting this is pushing ne way over. I'm 49 for crap sakes. I am so tired of the pain in my body and I am just tired, this is the last slap I can't anymore. Naturally alcohol I am sure is just about the end game along with cuts.
    Just want to bleed out and not hurt anymore and be so scared to leave my house or sleep. I just want to sleep forever.
  • Vyvanse for aspergers / autism and adhd working well
    Glad our child's condition was properly diagnosed and now is treated with this medication. Had to go to a team of experts to get the right diagnosis of Aspergers with ADHD, impulsive type. I'm sharing this in hopes some others will be consider a medication that can possibly help.
  • Suboxone buprenorphine/naloxone causing premature ejaculation (1 response)
    Hello, I've been a heroine smoker for 5 years. In that time I lost much of my libido which was strange because I was prity much a sex addict . Anyways I've been clean for a year and on saboxine. Before I got on saboxine I had a clean two months off of everything.i relapsed on heroine and decided saboxine was the best route methadone is poison I know (get off it ) ASAP if your on. When I was clean in those two months my sex drive came back and I was back to my old self. Know that I'm on Saboxine my sex drive sucks, so I started tapering. I have a beautiful women and my drive is back but I can"t hold a nut. It sucks she's meet all my x s and she knows I must of been doing something right because there all banging hot. I wanted to post this so other People don t think there going nuts( no Punt intended) if the same thing is happening to them. I guess my advice has to be I have to get off the subs I ain't chancing some of those s s r is because you could fuck up your sex life for good. If your gona go the pill route go daproxetine I here it's the safest. I'm gona look up hurbail rhymedies. I love ladies and love sex hopefully this problem will go away soon because drugs are fun but not worth a fine peace of ass. No drug is worth all this headache that's for sure. Saboxine does make you remember and start living life again but use it as a stepping tool don"t get stick on it

More reviews for: Methadone Hydrochloride, Vyvanse

Comments from related studies:

  • From this study (10 months ago):

  • I have had chronic pain since 2002 in my lower back and have had a spinal fusion with no help now I have developed this tingling and numbness mostly on the left leg at the top side and the right leg to

    Reply

  • From this study (3 years ago):

  • * Didn't start gaining weight until aftwer taking geodon for 2 yearas, however after 6 years on geodon I drastically lowered my dose without ANY weight loss. Also, the apetite lowering effects of the adderall and vyvanse have completely dissapeared after taking them for 2 years at very high doses (prescribed). Also, the Adderall XR lost a sgnificant part of its effectiveness after 7 years. The plus side to that is that it no longer causes nervousness/anxiety as a side effect. I am most concerned with my chest pain. Only noticed it this past year. Year 7 of Geodon and adderal. Seems worse if I take imediate release adderal. because the IR adderal often also causes my stomach pain I'm not sure if the pain is coming fronm my heart, lung or if it is acid reflux? But it is VERY WORRISOME!!

    Reply

Complete drug side effects:

On eHealthMe, Methadone Hydrochloride (methadone hydrochloride) is often used to treat pain. Vyvanse (lisdexamfetamine dimesylate) is often used to treat attention deficit hyperactivity disorder. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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