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Review: taking Methadone and Amitriptyline together

Summary: drug interactions are reported among people who take Methadone and Amitriptyline together.

This review analyzes the effectiveness and drug interactions between Methadone and Amitriptyline. It is created by eHealthMe based on reports of 907 people who take the same drugs from FDA and social media, and is updated regularly.

 

You are not alone: join a support group for people who take Methadone and Amitriptyline >>>

On Mar, 29, 2015: 907 people who take Methadone Hydrochloride, Amitriptyline Hydrochloride are studied

Methadone Hydrochloride, Amitriptyline Hydrochloride outcomes

Drug combinations in study:
- Methadone Hydrochloride (methadone hydrochloride)
- Amitriptyline Hydrochloride (amitriptyline hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Methadone Hydrochloride is effective25.00%
(1 of 4 people)
33.33%
(2 of 6 people)
33.33%
(1 of 3 people)
0.00%
(0 of 1 people)
66.67%
(2 of 3 people)
40.00%
(2 of 5 people)
33.33%
(1 of 3 people)
n/a
Amitriptyline Hydrochloride is effectiven/a8.33%
(1 of 12 people)
100.00%
(1 of 1 people)
0.00%
(0 of 3 people)
0.00%
(0 of 3 people)
0.00%
(0 of 2 people)
40.00%
(2 of 5 people)
n/a

Drug effectiveness by gender :

FemaleMale
Methadone Hydrochloride is effective25.00%
(2 of 8 people)
41.18%
(7 of 17 people)
Amitriptyline Hydrochloride is effective11.11%
(1 of 9 people)
17.65%
(3 of 17 people)

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Methadone Hydrochloride is effectiven/an/an/a66.67%
(2 of 3 people)
33.33%
(2 of 6 people)
12.00%
(3 of 25 people)
10.53%
(2 of 19 people)
0.00%
(0 of 5 people)
Amitriptyline Hydrochloride is effectiven/an/an/a0.00%
(0 of 2 people)
10.00%
(1 of 10 people)
7.69%
(2 of 26 people)
6.67%
(1 of 15 people)
0.00%
(0 of 5 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Blood Sodium DecreasedMultiple Drug Overdose AccidentalPainSeptic ShockMyocardial InfarctionHypotensionVomitingPain
ListlessMeningococcal InfectionPain In ExtremityHyperkalaemiaHepatic EncephalopathyNeutropeniaRed FaceAnxiety
Blood Potassium IncreasedHypotensionPeripheral Arterial Occlusive DiseaseTachycardiaPoor Peripheral CirculationDehydrationDry MouthNausea
Mental Status ChangesPneumoniaGangreneElectrocardiogram Qt ProlongedSuicide AttemptDiarrhoeaSicknessBack Pain
OverdosePeripheral Arterial Occlusive DiseaseDrug Exposure During PregnancyNauseaAbdominal BloatingHaemoglobin DecreasedParanoiaDizziness
MiosisTinnitusSomnolenceItchingPhantom PainHaematocrit DecreasedUrinary Bladder PolypPyrexia
LethargyPain In ExtremityOverdoseDizzinessParanoiaPain In ExtremityAgitationBone Disorder
Depressed Level Of ConsciousnessPainPremature BabySupraventricular TachycardiaMood SwingsWhite Blood Cell Count DecreasedItchingAsthenia
Palmar-plantar Erythrodysaesthesia SyndromeGangreneArterial Thrombosis LimbOedema PeripheralWeaknessPlatelet Count DecreasedWeight DecreasedWeight Decreased
FatigueArterial Thrombosis LimbMiosisCardiac DisorderLoss Of ConsciousnessDizzinessConstipationDyspnoea

Most common drug interactions by gender * :

FemaleMale
PainAsthenia
AnxietyWeight Decreased
NauseaDizziness
Bone DisorderConstipation
Pain In JawDepression
ArthralgiaPyrexia
Back PainFatigue
Emotional DistressBack Pain
Osteonecrosis Of JawDyspnoea
InjuryDrug Ineffective

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Developmental DelaySepsisn/aCardiac ArrestNauseaAstheniaPainPain
Drug Withdrawal Syndrome NeonatalCerebral InfarctionOverdoseCardiac ArrestWeight DecreasedAnxietyWeight Decreased
Drug Exposure During PregnancyCerebral HaemorrhageCompleted SuicideDyspnoeaBack PainPyrexiaOsteomyelitis
Neonatal DisorderRespiratory ArrestDeathConstipationBone DisorderBone Disorder
Congenital NystagmusRespiratory DepressionAnxietyDizzinessInsomniaBack Pain
StrabismusVomitingConvulsionFatigueArthralgiaImpaired Healing
NystagmusDrug AbuseHeadacheDepressionNauseaOsteoarthritis
Strabismus CongenitalInjection Site AbscessRespiratory ArrestPainPain In JawTooth Extraction
Refraction DisorderUnresponsive To StimuliConstipationPyrexiaFallRash
Maternal Drugs Affecting FoetusPyrexiaPainCompleted SuicideInjuryHypoaesthesia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of Methadone and Amitriptyline on

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You are not alone! Join a related support group:
- support group for people who take Amitriptyline Hydrochloride
- support group for people who take Methadone Hydrochloride

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Methadone Hydrochloride (methadone hydrochloride) is often used to treat pain. Amitriptyline Hydrochloride (amitriptyline hydrochloride) is often used to treat migraine. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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