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Review: Methadone and Methotrexate

This review analyzes the effectiveness and drug interactions between Methadone and Methotrexate. It is created by eHealthMe based on reports of 271 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: join a mobile support group for people who take Methadone and Methotrexate >>>

What are the drugs

Methadone hydrochloride (latest outcomes from 2,803 users) has active ingredients of methadone hydrochloride. It is used in pain.

Methotrexate (latest outcomes from 131,102 users) has active ingredients of methotrexate sodium. It is used in rheumatoid arthritis.

On Aug, 16, 2014: 271 people who take Methadone Hydrochloride, Methotrexate are studied

Methadone Hydrochloride, Methotrexate outcomes

Drug combinations in study:
- Methadone Hydrochloride (methadone hydrochloride)
- Methotrexate (methotrexate sodium)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Methadone Hydrochloride is effectiven/an/an/an/a100.00%
(3 of 3 people)
50.00%
(1 of 2 people)
n/an/a
Methotrexate is effective0.00%
(0 of 1 people)
0.00%
(0 of 1 people)
n/an/a0.00%
(0 of 1 people)
n/an/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Blood Bilirubin IncreasedChest PainHerpes ZosterWithdrawal SyndromeAbortion SpontaneousSkin Fissuresn/aPain
Acute Respiratory Distress SyndromeGait DisturbanceArthralgiaMalaisePsoriasisEye PainOedema Peripheral
PneumonitisOxygen Saturation DecreasedOedema PeripheralNon-small Cell Lung CancerPainEar PainAnaemia
HypernatraemiaHypersomniaMyocardial InfarctionFeeling HotArthralgiaSkin SensitisationDehydration
HypotensionBlood Potassium IncreasedPainAlopeciaUrinary Tract InfectionSkin Discoloration - BluishArthralgia
Pneumonia Respiratory Syncytial ViralTherapeutic Agent ToxicityFibromyalgiaPneumoniaNauseaMouth UlcerationWeight Decreased
HypoxiaSimilar Reaction On Previous Exposure To DrugImmune System DisorderInsomniaDizziness AggravatedPain - JointsDyspnoea
Cerebrovascular AccidentRenal Failure AcuteThyroid NeoplasmNodulesHot FlashesBone Disorder
PainPancytopeniaJoint SwellingAbnormal DreamsSkin Burning SensationChest Pain
Pain In ExtremityMemory ImpairmentCataractHyperglycaemiaSkin NecrosisPyrexia

Drug effectiveness by gender :

FemaleMale
Methadone Hydrochloride is effective80.00%
(4 of 5 people)
n/a
Methotrexate is effective0.00%
(0 of 3 people)
n/a

Most common drug interactions by gender * :

FemaleMale
PainDehydration
ArthralgiaOedema Peripheral
AnaemiaDizziness
NauseaVision Blurred
Oedema PeripheralPain
Drug IneffectiveHyperhidrosis
FatigueBlood Calcium Decreased
DyspnoeaChest Pain
Hodgkin's DiseaseBack Pain
VomitingDepression

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Methadone Hydrochloride is effectiven/an/an/an/an/a100.00%
(3 of 3 people)
3.12%
(1 of 32 people)
n/a
Methotrexate is effectiven/an/an/an/an/a0.00%
(0 of 2 people)
0.00%
(0 of 6 people)
n/a

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/aHodgkin's DiseaseHodgkin's DiseaseCardiomyopathy NosHyperglycaemiaPainArthralgiaPneumonia
SomnolenceAnaphylactic ReactionDyspnoea NosDehydrationOedema PeripheralBack PainHypoaesthesia
Septic ShockPneumonia Respiratory Syncytial ViralEjection Fraction AbnormalPain In ExtremityFibromyalgiaPainPain
Partial SeizuresHypernatraemiaGlossodyniaFatigueOsteonecrosis Of JawDrug IneffectiveChest Pain
NystagmusBlood Bilirubin IncreasedHypokinesiaOedema PeripheralCataractMusculoskeletal StiffnessNausea
TachycardiaHypotensionOedema Lower LimbArthralgiaHerpes ZosterHeadacheTooth Extraction
Vision BlurredAcute Respiratory Distress SyndromeDyspnoea ExertionalCoughAnaemiaAnaemiaAnaemia
PneumoperitoneumPneumonitisHeadacheHaemoptysisWeight DecreasedPain In ExtremityHyperhidrosis
Pneumatosis IntestinalisHodgkin's Disease Stage IiCardiac Failure CongestiveDyspnoeaConstipationAlopeciaVomiting
Acute Graft Versus Host DiseaseDrug IneffectiveDepressionDizzinessBone PainHaemoglobin DecreasedDry Mouth

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group:
- group for people who take Methadone and Methotrexate
- group for people who take Methadone Hydrochloride
- group for people who take Methotrexate

Comments from related studies:

  • From this study (4 months ago):

  • All lesions necrosis
    Painful granulomas
    I live in chronic pain and fatigue

    Reply

  • From this study (7 months ago):

  • I take methotexate weekly.. After a day of taking them, I have terrible chest pain that radiates to my neck, and down my sides

    Reply

  • From this study (2 years ago):

  • just want to know what drugs are safe to take with methadone for arthritis?

    Reply

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Complete drug side effects:

On eHealthMe, Methadone Hydrochloride (methadone hydrochloride) is often used to treat pain. Methotrexate (methotrexate sodium) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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