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Home > Methadone > Methotrexate > Methadone and Methotrexate

Review: Methadone and Methotrexate

Summary: drug interactions are reported among people who take Methadone and Methotrexate together.

This review analyzes the effectiveness and drug interactions between Methadone and Methotrexate. It is created by eHealthMe based on reports of 271 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Methadone and Methotrexate >>>

What are the drugs

Methadone hydrochloride (latest outcomes from 2,832 users) has active ingredients of methadone hydrochloride. It is often used in pain.

Trend of methadone hydrochloride reports

Methotrexate (latest outcomes from 131,185 users) has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis.

Trend of methotrexate reports

On Oct, 30, 2014: 271 people who take Methadone Hydrochloride, Methotrexate are studied

Methadone Hydrochloride, Methotrexate outcomes

Drug combinations in study:
- Methadone Hydrochloride (methadone hydrochloride)
- Methotrexate (methotrexate sodium)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Methadone Hydrochloride is effectiven/an/an/an/a100.00%
(3 of 3 people)
50.00%
(1 of 2 people)
n/an/a
Methotrexate is effective0.00%
(0 of 1 people)
0.00%
(0 of 1 people)
n/an/a0.00%
(0 of 1 people)
n/an/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Blood Bilirubin IncreasedChest PainHerpes ZosterWithdrawal SyndromeAbortion SpontaneousSkin Fissuresn/aPain
Acute Respiratory Distress SyndromeGait DisturbanceArthralgiaMalaisePsoriasisEye PainOedema Peripheral
PneumonitisOxygen Saturation DecreasedOedema PeripheralNon-small Cell Lung CancerPainEar PainAnaemia
HypernatraemiaHypersomniaMyocardial InfarctionFeeling HotArthralgiaSkin SensitisationDehydration
HypotensionBlood Potassium IncreasedPainAlopeciaUrinary Tract InfectionSkin Discoloration - BluishArthralgia
Pneumonia Respiratory Syncytial ViralTherapeutic Agent ToxicityFibromyalgiaPneumoniaNauseaMouth UlcerationWeight Decreased
HypoxiaSimilar Reaction On Previous Exposure To DrugImmune System DisorderInsomniaDizziness AggravatedPain - JointsDyspnoea
Cerebrovascular AccidentRenal Failure AcuteThyroid NeoplasmNodulesHot FlashesBone Disorder
PainPancytopeniaJoint SwellingAbnormal DreamsSkin Burning SensationChest Pain
Pain In ExtremityMemory ImpairmentCataractHyperglycaemiaSkin NecrosisPyrexia

Drug effectiveness by gender :

FemaleMale
Methadone Hydrochloride is effective80.00%
(4 of 5 people)
n/a
Methotrexate is effective0.00%
(0 of 3 people)
n/a

Most common drug interactions by gender * :

FemaleMale
PainDehydration
ArthralgiaOedema Peripheral
AnaemiaDizziness
NauseaVision Blurred
Oedema PeripheralPain
Drug IneffectiveHyperhidrosis
FatigueBlood Calcium Decreased
DyspnoeaChest Pain
Hodgkin's DiseaseBack Pain
VomitingDepression

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Methadone Hydrochloride is effectiven/an/an/an/an/a100.00%
(3 of 3 people)
3.12%
(1 of 32 people)
n/a
Methotrexate is effectiven/an/an/an/an/a0.00%
(0 of 2 people)
0.00%
(0 of 6 people)
n/a

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/aHodgkin's DiseaseHodgkin's DiseaseCardiomyopathy NosHyperglycaemiaPainArthralgiaPneumonia
SomnolenceAnaphylactic ReactionDyspnoea NosDehydrationOedema PeripheralBack PainHypoaesthesia
Septic ShockPneumonia Respiratory Syncytial ViralEjection Fraction AbnormalPain In ExtremityFibromyalgiaPainPain
Partial SeizuresHypernatraemiaGlossodyniaFatigueOsteonecrosis Of JawDrug IneffectiveChest Pain
NystagmusBlood Bilirubin IncreasedHypokinesiaOedema PeripheralCataractMusculoskeletal StiffnessNausea
TachycardiaHypotensionOedema Lower LimbArthralgiaHerpes ZosterHeadacheTooth Extraction
Vision BlurredAcute Respiratory Distress SyndromeDyspnoea ExertionalCoughAnaemiaAnaemiaAnaemia
PneumoperitoneumPneumonitisHeadacheHaemoptysisWeight DecreasedPain In ExtremityHyperhidrosis
Pneumatosis IntestinalisHodgkin's Disease Stage IiCardiac Failure CongestiveDyspnoeaConstipationAlopeciaVomiting
Acute Graft Versus Host DiseaseDrug IneffectiveDepressionDizzinessBone PainHaemoglobin DecreasedDry Mouth

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Methadone and Methotrexate?

You are not alone! Join a related mobile support group:
- support group for people who take Methadone and Methotrexate
- support group for people who take Methadone Hydrochloride
- support group for people who take Methotrexate

Recent conversations of related support groups:

Can you answer these questions (Ask a question):

  • Hlab27 antigen and unexplained scratches caused by accutane
    (Asked by a 49 year old woman who has Scratches, Swelling, Burning, Nerve, Muscle Pain, Conjunctivitis, and takes Methotrexate)
    Guinea pig user of Accutane 1982. Experimental drug (told at that time) when a woman hits menopause we are not sure what will happen. I have hit early menopause 42 to be exact. Conjunctivitis, unexplained swelling in fingers, toes, kness, pseudogout (not normal according to my rheumatologist) une ...

  • Can long-term methadone use cause or increase the risk of colon cancer?
    (Asked by a 57 year old man who has Chronic Pain, Failed Back Surgery Syndrome, and takes Fluticasone Propionate, Finasteride, Doxazosin Mesylate, Acetaminophen, Trazodone Hydrochloride, Butrans, Sertraline, Omeprazole, Simvastatin, Triamterene And Hydrochlorothiazide, Naproxen, Aspirin, Polyethylene Glycol 3350, Senna, Colace, Methadone Hydrochloride)
    I had a two-level spinal fusion at L4-S1 in 2000 after being injuried at work in Sept. 24, 1997. I lost everything after...the unjury, ability to do my job, my wife and family (couldn't take the strain) my home, my sense of self and purpose, direction and belonging...credit rating and ability to pay ...

  • Has anybody had multi lobar pneumonia from reaction to methotrexate?
    (Asked by a 57 year old woman who has Migraine Without Aura, Anxiety And Stress, Major Depression With Psychotic Features, Bilateral Multilobar Pneumonia, Ankylosing Spondylitis, and takes Zyprexa, Methotrexate)
    Bilateral multilobar pneumonia - rheumatologist considers it was caused by a reaction to methotrexate I was taking for ankylosing spondylitis and I was lucky to survive. Anyone have this and later shown to have scarring of the lungs?

  • I am a 56 year old female with rheumatoid arthritis. i also have found out i have osteoporosis. i keep getting right breast sensitivity also tingling and tenderness in right scapula area...
    (Asked by a 56 year old woman who has Hign Blood Pressure, Osteoporosis Postmenopausal, Rheumatoid Arthritis, and takes Methotrexate)
    I am a 56 year old female with tingling in my right shoulder blade and some tenderness. I have occasional breast discomfort in the same side and sometimes my rt. nipple feels sensitive. If I touch the area, the symptom on the nipple vanishes. at times the tingling travels into my neck and symptoms s ...

  • Can i take marijuana while taking gilenya
    (Asked by a 36 year old woman who has MS, and takes Gilenya)
    Hello i would like to know if is safe to have marijuane with gilenya and methotraxate

More questions for: Methadone Hydrochloride, Methotrexate

You may be interested at these reviews (Write a review):

  • 3 strong drugs together against neuropathic pain
    (Posted by a 49 year old man who has Ehlers-danlos Syndrome, Joint Hypermobility, Neuropathic Pain, and takes Pregabalin, Clonazepam, Methadone Hydrochloride)
    Neuropathic pain debuted when I was 24, now I'm 50. Received diagnosed with Ehler-Danlos syndrome (EDS), joint hypermobility type, when I was 35 years old. So it can take some time to get a diagnose. And as EDS-patient I do not belong to any clinic. Orthopedics says that EDS is not orthopedic, rheum ...

  • Nexium improves my constipation
    (Posted by a 53 year old woman who has Constipation, GERD, and takes Lyrica, Methadone Hydrochloride, Lipitor)
    Started taking Nexium 1 week ago and I noticed improvement with my chronic constipation.

  • Humira: my experience
    (Posted by a 66 year old man who has Ankylosing Spondylitis, Reiter's Syndrome, Psoriatic Arthritis, and takes Methotrexate Preservative Free, Enbrel, Humira)
    I have had some form of arthritis probably since birth. My father and maternal grandfather had some form of arthritis. I began to realize pain in both ankles if I stood or walked too long. I began taking many NSAIDs when I was around 22. I've done gold, prednisone (twice), plaquenil, butazoidin, ...

  • Xanax bed wetting will it stop and do i wear diapers or die
    (Posted by a 48 year old man who has Bedwetting, Confusion, Bone And Joint Pain, Adjustment Disorder With Mixed Anxiety And Depressed Mood, Depression Suicidal, Backaches And Stress, and takes Xanax, Acetaminophen, Wellbutrin, Methadone Hydrochloride, Norco)
    I am on the very edge of crazy. So starting this is pushing ne way over. I'm 49 for crap sakes. I am so tired of the pain in my body and I am just tired, this is the last slap I can't anymore. Naturally alcohol I am sure is just about the end game along with cuts. Just want to bleed out and not hur ...

  • Psoratic arthritis and trigeminal neuralgia
    (Posted by a 33 year old man who has Nasal Septum Deviation, Psoriasis, Psoriatic Arthritis, Trigeminal Neuralgia, Asthma Exercise Induced, and takes Methotrexate)
    hi i suffer from psorisis and psoratic athritis i was just diagnosed with trigeminal neuralgia i was looking for the connection between the two and i see that there is one from your study the thing is all 13 people in the study said to have psoriatic arthropathy yet only one said to have psoratic a ...

More reviews for: Methadone Hydrochloride, Methotrexate

Complete drug side effects:

On eHealthMe, Methadone Hydrochloride (methadone hydrochloride) is often used to treat pain. Methotrexate (methotrexate sodium) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug studies (Check your drugs):

More related studies for: Methadone Hydrochloride, Methotrexate

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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