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Review: taking Methadose and Mirapex together

Summary: drug interactions are reported among people who take Methadose and Mirapex together.

This review analyzes the effectiveness and drug interactions between Methadose and Mirapex. It is created by eHealthMe based on reports of 53 people who take the same drugs from FDA and social media, and is updated regularly.

 

 

 

 

You are not alone: join a mobile support group for people who take Methadose and Mirapex >>>

What are the drugs

Methadose has active ingredients of methadone hydrochloride. It is often used in pain. (latest outcomes from 2,391 Methadose users)

Mirapex has active ingredients of pramipexole dihydrochloride. It is often used in restless leg syndrome. (latest outcomes from 10,317 Mirapex users)

On Feb, 1, 2015: 53 people who take Methadose, Mirapex are studied

Methadose, Mirapex outcomes

Drug combinations in study:
- Methadose (methadone hydrochloride)
- Mirapex (pramipexole dihydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Methadose is effectiven/a100.00%
(1 of 1 people)
n/an/a0.00%
(0 of 1 people)
n/a100.00%
(1 of 1 people)
n/a
Mirapex is effectiven/an/an/a0.00%
(0 of 1 people)
50.00%
(1 of 2 people)
n/an/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Colonic FistulaExhaustion, Fatigue, Lethargy, Tiredness, Wearinessn/aObsessive-compulsive DisorderCataplexyn/aMyopathy SteroidPneumonia
OverdoseDystoniaLanguage Disorder - ExpressiveStiff NeckPain In Extremity
HyperhidrosisLanguage Disorder - ExpressiveExhaustion, Fatigue, Lethargy, Tiredness, WearinessCrohn's Disease
NauseaCataplexySpasticityBurning Sensation
Abdominal PainSpasm Of The EsophagusSpasm Of The EsophagusBlood Glucose Increased
Back PainSpasticityMyopathy SteroidPeripheral Coldness
PyrexiaNeuropathy - PeripheralStiff NeckNausea
MalaiseRestless Legs SyndromeDystoniaAnxiety
Tooth InfectionNumbness And TinglingNeuropathy - PeripheralJoint Range Of Motion Decreased
Electrocardiogram Qt ProlongedMusculoskeletal StiffnessPain - JointsMalnutrition

Drug effectiveness by gender :

FemaleMale
Methadose is effective0.00%
(0 of 1 people)
100.00%
(2 of 2 people)
Mirapex is effective0.00%
(0 of 1 people)
50.00%
(1 of 2 people)

Most common drug interactions by gender * :

FemaleMale
Pain In ExtremityPneumonia
Burning SensationCrohn's Disease
Grip Strength DecreasedMalnutrition
Joint Range Of Motion DecreasedBlood Glucose Increased
Hand DeformityBlood Sodium Decreased
HypokinesiaBlood Amylase Decreased
Peripheral ColdnessBlood Alkaline Phosphatase Increased
Sensory LossBlood Urea Increased
NauseaActivated Partial Thromboplastin Time Prolonged
Viith Nerve ParalysisCondition Aggravated

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Methadose is effectiven/an/an/an/an/a6.25%
(1 of 16 people)
n/a50.00%
(1 of 2 people)
Mirapex is effectiven/an/an/an/an/a0.00%
(0 of 16 people)
n/a50.00%
(1 of 2 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/an/aColonic FistulaNauseaArteriosclerosis Coronary ArteryViith Nerve ParalysisHand Deformity
OverdoseInfectionPulmonary OedemaHerpes Zoster OticusGrip Strength Decreased
PneumoniaCrohn's DiseaseDizzinessWeight DecreasedBurning Sensation
MalnutritionAphagiaDyspnoeaNauseaHypokinesia
PyrexiaAbdominal Pain UpperHypotensionOsteoarthritisJoint Range Of Motion Decreased
Electrocardiogram Qt ProlongedVomitingChest PainPneumoniaSensory Loss
Crohn's DiseaseAnal AbscessDrug Withdrawal SyndromeUrinary Tract InfectionPeripheral Coldness
MalaiseAccidental OverdoseMeningiomaHypertensionPain In Extremity
HyperhidrosisPneumoniaAtrioventricular Block First DegreeHyponatraemia
Condition AggravatedTachycardiaNeck PainPneumonia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Methadose and Mirapex?

You are not alone! Join a related mobile support group:
- support group for people who take Methadose and Mirapex
- support group for people who take Methadose
- support group for people who take Mirapex

Can you answer these questions (Ask a question):

  • Does humira cause excessive sweating?
    Having psoriaticarthritis,fibromyalgia,psoriais,restless leg syndrome,roseacea and high blood pressure means complex health issues and a complex list of medication to go with it. Iam suffering extreme sweating,flushing and now a tickled cough. Now it could be due to going through the change (menopause) but that started a year ago and although I was getting the flushes and sweating,it was nothing like it is now! To me,it seems the excessive sweating started roughly a month after taking Humira. Having so many health issues I'm in tune with any changes and note and monitor them. I started Humira 10 months ago now. My Psoriasis has cleared completely so I'm really pleased. Usually,there's a trade off and you end up with something else! Could the issues I have be down to a single drug on the list,or a combination?
  • Can i take ketorolac if i am already taking methadone everyday?
    I take methadone everyday and I have a tooth ache so can I take ketorolac with methadone?
  • Can long-term methadone use cause or increase the risk of colon cancer?
    I had a two-level spinal fusion at L4-S1 in 2000 after being injuried at work in Sept. 24, 1997. I lost everything after...the unjury, ability to do my job, my wife and family (couldn't take the strain) my home, my sense of self and purpose, direction and belonging...credit rating and ability to pay my bills.
    After a long period of waiting to settle my workmens' comp. case, I returned home, from the Bat Area back to Arizona to take of my mother with a yet un dianosed case of moderate dementia.
    Then, in 2011 I had a 2nd surgery to relieve spinal stenosis btwn. L2-L4, just above the fusion site.
    I've been taking methadone since early 2004, a little over ten years, now. I've had high blood pressure since my injury.

    Now, I waiting to be scheduled for a colonoscopy, with my father having had polyps and the way I've been feeling..drained, tired all the time, and stomach pains ( in addition to my chronic low back pain), I...
    find myself wondering if there is any relationtionship between the methadone and other meds and cancer?
  • How well does using both mirapex and neupro at the same timne work
    Off of mirapex because of sexual thoughts, but Neupro does not work nearly as well (at 8 mg/day). I'm curious about using a much lower dose of Mirapex along with Neupro.
  • Can methadone cause my aynurism to burst?
    A doctor is lowering my dose of Methadone I take for severe back pain due to my aneurysm because he said the Methadone could cause a stroke w/my aneurysm. Has anyone else heard of this? Thank you!!!

More questions for: Methadose, Mirapex

You may be interested at these reviews (Write a review):

  • Are you mental on methadone
    My doctor changed my pain medication back in May of 2014 . I was pleased with how well it handle my back pain and was pleased with how inexpensive it was. My husband had been using the same drug with great results. It wasn't until about a month later I started to notice just feelings of sadness. I didn't think too much of it but then I would get such strong feelings of despair really bad that I would just cry. I also started getting a lot of panic attacks I had so much anxiety at times it prevented me from doing things. At one point I really thought I was having some sort of break down, but the feelings would have highs and lows and sometimes I would have a day with out them. Eventually after being on them for 7 months I went to my doctor and asked if it were possible I was experiencing these feelings from the Methadone. He wasn't sure but with it all happening right after I started taking them he decided to put me on something else. It's been about three weeks and even though the feelings are still there they are not as strong and seem to be passing. I hope as time goes I will feel like myself again and hope never to have to experience something like that again.
  • Methadone and forgetting basic things.
    I have been in MMT (Methadone Maintenance Treatment) for around 7 1/2 years for chronic pain. I have gotten to where I forget things that I never would or did before and the longer in time the worse it has gotten I am currently looking at some different meds for treatment. The loss of memory is everything from childhood memories to what I did yesterday I may pay something and if I dont write it diwn I will forget it things I have known all my life I have forgotten. I can't say 100% it is from the MMT or not however I will sag I had no such problems before and I am at age 38 so I believe I am much too young to have severe memory loss that I am currently experiencing and whats scary is what if it never comes back and continues to decline?
  • 3 strong drugs together against neuropathic pain
    Neuropathic pain debuted when I was 24, now I'm 50. Received diagnosed with Ehler-Danlos syndrome (EDS), joint hypermobility type, when I was 35 years old. So it can take some time to get a diagnose. And as EDS-patient I do not belong to any clinic. Orthopedics says that EDS is not orthopedic, rheumatology says that EDS is not an autoimmune disease, GPs say that EDS is too difficult, and so on. Sooner or later we all end up at Psychiatry, even if we are not depressed.

    The first kind of pain I got when I was 24 came from low back, but I experienced as pelvic pain and leg pain. It was clearly a neuropathic pain, but it took years to find out. Later it was treated by a pain clinic with cortisone around the genitofemoral nerves (both sides). Since this treatment didn't result in lasting freedom from pain, the pain clinic started to give me RF (radio frequency) treatment. This made the pain disappeared after one year, and I was 80% free from it between 2002 and 2014, 12 years. The pain doctors said pain could return after 10 years.

    The other kind of neuropathic pain started 2003 with intense stomach pain. During 6 months I could hardly eat nothing due to nausea and vomiting. After this 6 months, stomach pain changed to almost unbearable pain in upper back.
    What happened 2003, and what all the doctors missed, was that the right lowest ribs slid up over the sternum. This rib dislocation is till there today, but now with a lot of cartilage formed around the rib where it is stuck in the lower end of the sternum. The dislocation is clearly visible on X-ray. This has greatly affected the thoracic spine. I have a scoliosis which I had not before 2003. And I still have severe pain in the thoracic spine.

    It was initially treated with morphine daily, and later with Durogesic (fentanyl), but this didn't help much. 2005 I was hospitalized because I had too much pain to take care of myself and my hygiene. After some months the doctors started to give me clonazepam because the muscles along the spine was in a chronic seizures. Clonazepam helped, but I could still have a lot of pain in two vertebrae in the thoracic spine. It felt as if someone drilled into the vertebrae without anesthesia. After a few months, doctors also prescribed me methadone. Then the pain disappeared almost completely. Since 2006, I have eaten clonazepam and methadone every day, and I need to sleep in an armchair to not get more pain because of moving during sleep.

    There are side effects. After 1,5 years with clonazepam and methadone I started to have panic attacks. Or rather one long panic attack which didn't stop before I got treatment with amitryptilin and pregabalin (Lyrica). These 2 medicines stopped the panic disorder completely after some hours, and the panic was then gone. Then I got side effects of these 2 medicines, amitryptilin & Lyrica, too. I gained a lot of weight (from 83 to 148 kg) and got much water (edema) in both my legs under the knees and in both feet. The feet could swallow to the double size. 2012 I stopped with amitryptilin and started to loose weight again (in Aug 2014 below 80 kg) and get less water in my legs. Today I eat as little medicines I can, but I have to take methadone, clonazepam and Lyrica every day, twice. If I try to take away one of these 3 medicines, I got pain problems at once. Lyrica is the most painful one to take away. In Sept-Dec 2013 I lowered Lyrica from 300 mg daily, to 150, then to 75 and finally 0 mg. The pain I had was extremely difficult to handle. It didn't help to take more methadone or anything else. I have checked on Internet and found that many people got pain from quitting with Lyrica. Most people start eating it again. So did I. But 2006 and 2007 it was enough to treat the pain with methadone and clonazepam, I got the Lyrica against anxiety not pain. But today I take Lyrica against pain.

    Beside weight gain and leg edema, clonazepam and Lyrica significantly affect the sexual desire. And Lyrica alone makes it almost impossible to ejaculate. All four drugs together (clonazepam, methadone, amitryptiline and Lyrica), make one forget all about sex life. You don't even miss it. When I stopped with amitryptiline and lowered Lyrica (still taking clonazepam and methadone), I could suddenly easily get erections again, feel desire, but not getting orgasms. This is quite difficult to deal with.

    The pain pattern is greatly affected, by pain and by the medicines. So is the mood. I get something which feels like heavy depression, especially if I take the medicines late that day. I should take a medicine like methadone 3 times a day, because the effects of the tablet lasts around 8 hours. But I take them every 12 hours, to have a low consumption in case doctors prescribe them too late (which happens, and then it's good to have a spouse going to the pharmacy buying them for you, because you have too much pain to go yourself).

    Since methadone is also used for treating heroine addicts, medical staff treat you with disrespect when they see that it says "methadone" in your health record. I need to show a certificate that says that I deal with chronic neuropathic pain, that I never have had problems with drug addiction, to get normal respect.

    I wanted to share this because I think I am alone in the world with these medicines in combination against neuropathic pain caused by hypermobile joints, joint dislocation and muscle spasms. After trying almost everything else, including surgery cutting nerves, methadone, clonazepam and Lyrica seems to be the only way to kill my pain. But it's a life where you always is questioned, because of the use of methadone. I can guarantee that everybody in the world should accept these medicines if they had experienced the unbearable pain I had in upper back before they started to give me clonazepam and methadone.
  • Nexium improves my constipation
    Started taking Nexium 1 week ago and I noticed improvement with my chronic constipation.
  • Xanax bed wetting will it stop and do i wear diapers or die (1 response)
    I am on the very edge of crazy. So starting this is pushing ne way over. I'm 49 for crap sakes. I am so tired of the pain in my body and I am just tired, this is the last slap I can't anymore. Naturally alcohol I am sure is just about the end game along with cuts.
    Just want to bleed out and not hurt anymore and be so scared to leave my house or sleep. I just want to sleep forever.

More reviews for: Methadose, Mirapex

Comments from related studies:

  • From this study (2 years ago):

  • I recently was tested for Copper, and my labs show that it is double. There has been no liver problems in our family. The Celebrex I am taking (as well as many others) has warnings on it that it could affect other parts of the body. I am wondering if my problems are now caused by the medications, and what can be done to reverse what they have acused.

    Reply

Complete drug side effects:

On eHealthMe, Methadose (methadone hydrochloride) is often used to treat pain. Mirapex (pramipexole dihydrochloride) is often used to treat restless leg syndrome. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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