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Home > Methotrexate > Tylenol > Methotrexate and Tylenol

Review: Methotrexate and Tylenol

Summary: drug interactions are reported among people who take Methotrexate and Tylenol together.

This review analyzes the effectiveness and drug interactions between Methotrexate and Tylenol. It is created by eHealthMe based on reports of 4,881 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Methotrexate and Tylenol >>>

What are the drugs

Methotrexate (latest outcomes from 131,185 users) has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis.

Trend of methotrexate reports

Tylenol (latest outcomes from 55,612 users) has active ingredients of acetaminophen. It is often used in pain.

Trend of tylenol reports

On Nov, 12, 2014: 4,881 people who take Methotrexate, Tylenol are studied

Methotrexate, Tylenol outcomes

Drug combinations in study:
- Methotrexate (methotrexate sodium)
- Tylenol (acetaminophen)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Methotrexate is effectiven/a0.00%
(0 of 5 people)
100.00%
(1 of 1 people)
50.00%
(1 of 2 people)
0.00%
(0 of 4 people)
0.00%
(0 of 5 people)
100.00%
(1 of 1 people)
n/a
Tylenol is effective50.00%
(1 of 2 people)
n/an/a0.00%
(0 of 4 people)
20.00%
(1 of 5 people)
0.00%
(0 of 2 people)
0.00%
(0 of 5 people)
100.00%
(1 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
PyrexiaNauseaPneumonitisPneumoniaPneumoniaDeep Vein ThrombosisAstheniaPyrexia
NauseaPyrexiaPneumoniaPyrexiaPyrexiaThrombocytopeniaHeadacheNausea
HypotensionVomitingSepsisRespiratory FailureErysipelasPyrexiaAgranulocytosisDyspnoea
DehydrationPneumoniaLiver Function Test AbnormalMulti-organ FailureHerpes ZosterNon-small Cell Lung Cancer Stage IiibOedema PeripheralArthralgia
VomitingRheumatoid ArthritisInfectionSepsisPharyngitis StreptococcalMouth UlcerationChillsPain
Febrile NeutropeniaCondition AggravatedDehydrationGeneral Physical Health DeteriorationRheumatoid ArthritisPurpuraMyocardial InfarctionHeadache
HyperglycaemiaRashTuberculosisVomitingNauseaCoughChest PainVomiting
DyspnoeaDyspnoeaWeight DecreasedLung DisorderDyspnoeaPancytopeniaCandidiasisFatigue
Respiratory FailureHeadacheAlanine Aminotransferase IncreasedDisseminated TuberculosisFatigueWeight DecreasedPyrexiaOedema Peripheral
HypoalbuminaemiaColitisNauseaAnaemiaCoughHeadacheDehydrationDiarrhoea

Drug effectiveness by gender :

FemaleMale
Methotrexate is effective20.00%
(3 of 15 people)
0.00%
(0 of 3 people)
Tylenol is effective14.29%
(2 of 14 people)
33.33%
(1 of 3 people)

Most common drug interactions by gender * :

FemaleMale
NauseaPyrexia
PyrexiaNausea
HeadachePneumonia
DyspnoeaDyspnoea
PainFatigue
ArthralgiaArthralgia
VomitingVomiting
FatiguePain
DiarrhoeaHypotension
FallCough

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Methotrexate is effectiven/an/a0.00%
(0 of 1 people)
0.00%
(0 of 1 people)
0.00%
(0 of 2 people)
50.00%
(1 of 2 people)
4.76%
(1 of 21 people)
7.14%
(1 of 14 people)
Tylenol is effectiven/an/a0.00%
(0 of 1 people)
0.00%
(0 of 1 people)
0.00%
(0 of 2 people)
0.00%
(0 of 2 people)
5.56%
(1 of 18 people)
13.33%
(2 of 15 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Central Line InfectionPyrexiaFebrile NeutropeniaPyrexiaDyspnoeaNauseaHeadachePyrexia
Bronchial HyperreactivityTremorMucosal InflammationPainPyrexiaHeadachePainDyspnoea
AscitesNauseaArthralgiaArthralgiaPruritusPyrexiaArthralgiaPneumonia
Staphylococcal InfectionTachycardiaVomitingHeadacheVomitingPainNauseaNausea
Acute Circulatory FailureDiarrhoeaCrohn's DiseaseNauseaHeadacheArthralgiaPyrexiaOedema Peripheral
Angioneurotic OedemaVomitingPyrexiaDizzinessNauseaDyspnoeaDyspnoeaAtrial Fibrillation
Respiratory DistressTracheobronchitisFebrile Bone Marrow AplasiaDyspnoeaDehydrationFatigueBack PainPain
Lobar PneumoniaAscitesMulti-organ FailureDiarrhoeaCoughVomitingDiarrhoeaArthralgia
Condition AggravatedRespiratory FailureMuscular WeaknessCrohn's DiseaseHyperglycaemiaOedema PeripheralVomitingFatigue
Bacteria Stool IdentifiedPseudomonal BacteraemiaPain In ExtremityInfusion Related ReactionDiarrhoeaChest PainAstheniaFall

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Methotrexate and Tylenol?

You are not alone! Join a related mobile support group:
- support group for people who take Methotrexate and Tylenol
- support group for people who take Methotrexate
- support group for people who take Tylenol

Recent conversations of related support groups:

Can you answer these questions (Ask a question):

  • Can a drug test result return positive for amphetamine using 500mg tylenol extra strength
    (Asked by a 57 year old man who has Headache, and takes Tylenol)
    Can a drug test result return positive for amphetamine using 500mg tylenol extra strength?

  • Can unexplained hypertension be cause by a partial thyroidectomy?
    (Asked by a 50 year old man who has BP 135/77 Even After Increasing Meds, and takes Acetaminophen, Fluticasone Propionate, Allegra D 24 Hour, Nexium, Valsartan, Metoprolol Succinate, Amlodipine Besylate)
    Doc is trying to figure out why the BP suddenly spiked. I started an exercise regimen after a stress test. I had to be on Metoprolol just to pass the test. Results were no heart-related issues. Lost 6lbs. since starting exercise and don't know if this is Thyroidal or not. No discussion with the ...

  • Does zoloft cause ringing in the ears, like tinnitus? i've been on it for a month and noticed the ringing in the ears about a week ago, and it's just constant ringing and it's driving me insane.
    (Asked by a 24 year old man who has Ringing In The Ears, and takes Dicyclomine Hydrochloride, Benadryl, Tylenol, Lialda, Azathioprine, Prednisone, Ambien, Zoloft)
    I've been on most of the medications for more than a year and it hasn't been that bad getting used to them. But I've been on Zoloft and ambien for about a month now, and I've been noticing a lot of side effects. The one I just recently noticed and that has been driving me completely insane, is the r ...

  • Hlab27 antigen and unexplained scratches caused by accutane
    (Asked by a 49 year old woman who has Scratches, Swelling, Burning, Nerve, Muscle Pain, Conjunctivitis, and takes Methotrexate)
    Guinea pig user of Accutane 1982. Experimental drug (told at that time) when a woman hits menopause we are not sure what will happen. I have hit early menopause 42 to be exact. Conjunctivitis, unexplained swelling in fingers, toes, kness, pseudogout (not normal according to my rheumatologist) une ...

  • Can long-term methadone use cause or increase the risk of colon cancer?
    (Asked by a 57 year old man who has Chronic Pain, Failed Back Surgery Syndrome, and takes Fluticasone Propionate, Finasteride, Doxazosin Mesylate, Acetaminophen, Trazodone Hydrochloride, Butrans, Sertraline, Omeprazole, Simvastatin, Triamterene And Hydrochlorothiazide, Naproxen, Aspirin, Polyethylene Glycol 3350, Senna, Colace, Methadone Hydrochloride)
    I had a two-level spinal fusion at L4-S1 in 2000 after being injuried at work in Sept. 24, 1997. I lost everything after...the unjury, ability to do my job, my wife and family (couldn't take the strain) my home, my sense of self and purpose, direction and belonging...credit rating and ability to pay ...

More questions for: Methotrexate, Tylenol

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    I am on the very edge of crazy. So starting this is pushing ne way over. I'm 49 for crap sakes. I am so tired of the pain in my body and I am just tired, this is the last slap I can't anymore. Naturally alcohol I am sure is just about the end game along with cuts. Just want to bleed out and not hur ...

  • Penicillin vk induced drowsiness
    (Posted by a 28 year old man who has Pain - Ear, and takes Acetaminophen, Penicillin-vk)
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More reviews for: Methotrexate, Tylenol

Complete drug side effects:

On eHealthMe, Methotrexate (methotrexate sodium) is often used to treat rheumatoid arthritis. Tylenol (acetaminophen) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug studies (Check your drugs):

More related studies for: Methotrexate, Tylenol

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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