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Related topic: Methotrexate, Tylenol

Review: Methotrexate and Tylenol

This review analyzes the effectiveness and drug interactions between Methotrexate and Tylenol. It is created by eHealthMe based on 4,855 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Mar, 30, 2014: 4,855 people who reported to have interactions when taking Methotrexate, Tylenol are studied

Trend of Methotrexate, Tylenol's drug interactions, side effects and effectiveness reports (8547738)

Drug combinations in study:
- Methotrexate (methotrexate sodium)
- Tylenol (acetaminophen)

eHealthMe real world results:

Most common interactions experienced by people in the use of Methotrexate, Tylenol:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Pyrexia (fever)1,458
Dyspnoea (difficult or laboured respiration)1,291
Arthralgia (joint pain)1,274
Vomiting1,013
Diarrhoea905
Nausea (feeling of having an urge to vomit)868
Pain835
Headache (pain in head)750
Fatigue (feeling of tiredness)670
Oedema Peripheral (superficial swelling)548

Most common interactions experienced by people in long term use of Methotrexate, Tylenol:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Pyrexia (fever)129
Asthenia (weakness)97
Pneumonia96
Respiratory Failure (inadequate gas exchange by the respiratory system)78
Vomiting70
Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)69
Headache (pain in head)55
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)52
Sepsis (a severe blood infection that can lead to organ failure and death)49
Nausea (feeling of having an urge to vomit)46

How effective are the drugs:

not at allsomewhatmoderatehighvery high
Methotrexate0.00%16.67%66.67%16.67%0.00%
Tylenol0.00%0.00%100.00%0.00%0.00%

Top conditions involved for these people * :

  1. Rheumatoid arthritis
  2. Pain
  3. Premedication
  4. Hypertension
  5. Crohn's disease

Top co-used drugs for these people * :

  1. Folic acid
  2. Remicade
  3. Prednisone
  4. Humira
  5. Golimumab

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Complete drug side effects:

On eHealthMe, Methotrexate (methotrexate sodium) is often used to treat rheumatoid arthritis. Tylenol (acetaminophen) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (8 months ago):

  • I am having most of the symptoms of Hypothyroid, weight gain, very dry skin & hair, easily stressed, palpitations yet my doctor tells me my bloods are normal. No one seems to know why I am feeling so bad all the time.

    Reply

  • From this study (12 months ago):

  • I want to know if in fact there is a relation between these conditions and if there is any possibility that the adderall which he used for years before getting the other two conditions has anything to do with the two. Also if the chronic asthma medications he was exposed as a baby (proventyl, pulmicort and prednisone). Fyi child has allergy to amoxil. Thank you.

    Reply

  • From this study (1 year ago):

  • have not started cipralex yet - conce4rned about warfarin mix

    Reply

    Joe T on Feb, 26, 2013:

    I am on Methotrexate fir the past year, been taking it as a sub cutaneous 20mg injection once weekly.

    About 3 months ago i started to take cipralex(lexapro) 10mg daily. I seem to tolerate ut very well. Cipralex have improved my axiety/mood swings to a great deal, additionally i havent taken one pill of NSAID for the past 3 months. I used to take about 3-4 pills of Arcoxia every week. I am not sure if Cipralex numbs y joints pain, or if Methotrexate is working better, all i know is thank God i am doing well physically and psychologically things seem to be in a balance!

    I am male, 28 years of age. I do regular blood tests every 6 weeks. These include liver function tests, kidney function test, erythrocyte sedimentation rate, C reactive protein, and Complete blood count. All my reasults have always been in range with the normal limits.

    I hope my answer helps.

    Cheers,

    Joe

    Reply

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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