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Review: Methylprednisolone and Benadryl

This review analyzes the effectiveness and drug interactions between Methylprednisolone and Benadryl. It is created by eHealthMe based on 348 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

On Apr, 5, 2014: 348 people who reported to have interactions when taking Methylprednisolone, Benadryl are studied

Trend of Methylprednisolone, Benadryl's drug interactions, side effects and effectiveness reports (7436821)

Drug combinations in study:
- Methylprednisolone (methylprednisolone)
- Benadryl (diphenhydramine hydrochloride)

eHealthMe real world results:

Most common interactions experienced by people in the use of Methylprednisolone, Benadryl:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Pyrexia (fever)147
Arthralgia (joint pain)129
Dyspnoea (difficult or laboured respiration)127
Fatigue (feeling of tiredness)123
Fall98
Nausea (feeling of having an urge to vomit)94
Back Pain88
Abdominal Pain83
Depression81
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)80

Most common interactions experienced by people in long term use of Methylprednisolone, Benadryl:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Appendicitis (inflammation of the appendix)5
Fasciculations Of Muscle (twitching of voluntary muscle of body)3
Muscle Cramps Aggravated (painful sensations caused by muscle contraction)2
Umbilical Hernia (an outward bulging (protrusion) of the abdominal lining or part of the abdominal organ(s) through the area around the belly button)2
Mucosal Inflammation (infection of mucous membrane)2
Neuroma (tumour of nerve tissue)2

How effective are the drugs:

not at allsomewhatmoderatehighvery high
Methylprednisolone0.000.000.000.000.00
Benadryl0.00%100.00%0.00%0.00%0.00%

Top conditions involved for these people * :

  1. Premedication
  2. Pain
  3. Prophylaxis
  4. Hypersensitivity
  5. Hypertension

Top co-used drugs for these people * :

  1. Medrol
  2. Diphenhydramine hcl
  3. Acetaminophen
  4. Prednisone
  5. Prilosec

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Benadryl, Methylprednisolone

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Complete drug side effects:

On eHealthMe, Methylprednisolone (methylprednisolone) is often used to treat inflammation. Benadryl (diphenhydramine hydrochloride) is often used to treat allergies. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (4 years ago):

  • Is ok to take benadryl if i'm taking medrol?

    Reply

  • From this study (5 years ago):

  • CAN THESE THREE ITEMS BE TAKEN TOGETHER AND WHAT ARE THE POSSIBLE SIDE EFFECTS?

    Reply

Can you answer these questions (what is this?):

  • Nasal and chest infection and congestion
    I have been suffering stuffy nose and chest congestion and swelling of cheek bones due to infection, started taking methyprednisone and yesterday and no relieve as of yet i am getting worse.

  • Have benadryl users ever experienced sudden onset hearing loss in one ear? does i hearing return?
    I've been taking Benadryl tablets to control intense itching for the past two months or so. My last tablet was 2 days ago. Today, over the course of 2 hours, I've lost a significant amount of hearing in one ear. Has anyone else experienced this? Was your hearing restored, and if so, with treatmen ...

  • How do you know for sure benadryl caused the hair loss
    I'm 36 years old and have been taking Benadryl to help sleep for 6-8 months, 4-5 nights a week. The past couple months I've noticed a ton of shedding especially around my crown towards the mid to back of my part and now see my scalp through the hair that is still there. I'm starting to panic and ha ...

More questions for: Benadryl, Methylprednisolone

You may be interested at these reviews (what is this?):

  • Leg pain and occasional arm and hand pain
    I started having leg pains at night, lower leg felt like the muscle and bone were being pulled causing sharp pain. It was relieved by getting up and walking but would last most of the night. I finally realized after suffering this over and over for months, that it only happened when I had taken be ...

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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