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Review: taking Miralax and Colace together

Summary: drug interactions are reported among people who take Miralax and Colace together.

This review analyzes the effectiveness and drug interactions between Miralax and Colace. It is created by eHealthMe based on reports of 691 people who take the same drugs from FDA and social media, and is updated regularly.





You are not alone: join a mobile support group for people who take Miralax and Colace >>>

What are the drugs

Miralax has active ingredients of polyethylene glycol 3350. It is often used in constipation. (latest outcomes from 9,279 Miralax users)

Colace has active ingredients of docusate . It is often used in constipation. (latest outcomes from 1,310 Colace users)

On Feb, 3, 2015: 691 people who take Miralax, Colace are studied

Miralax, Colace outcomes

Drug combinations in study:
- Miralax (polyethylene glycol 3350)
- Colace (docusate )

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Miralax is effective0.00%
(0 of 4 people)
(1 of 4 people)
(1 of 2 people)
(0 of 3 people)
(1 of 2 people)
Colace is effective0.00%
(0 of 3 people)
(0 of 4 people)
(0 of 3 people)
(1 of 3 people)
(0 of 2 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DehydrationPneumonia Fungaln/aLoss Of Control Of LegsHallucination, AuditoryMuscle MassLoss Of Control Of LegsPain
Febrile NeutropeniaChest PainLoss Of AppetiteLoss Of AppetiteNausea
Prostate CancerDyskinesiaMuscle Contractions InvoluntaryMuscle Contractions InvoluntaryConstipation
HyperbilirubinaemiaFebrile NeutropeniaSwellingSwellingDyspnoea
Pulmonary EmbolismAbdominal PainSacral PainSacral PainVomiting
General Physical Health DeteriorationMuscle SpasmsInflammatory PainInflammatory PainPyrexia
Loss Of ConsciousnessSystemic MycosisChest PainChest PainAnxiety
EncephalitisSinusitis FungalFallFallAnaemia
Blood Potassium DecreasedFungal RhinitisNight SweatsNight SweatsFall
ConstipationLeukaemia RecurrentHeadacheHeadacheFatigue

Drug effectiveness by gender :

Miralax is effective25.00%
(2 of 8 people)
(1 of 7 people)
Colace is effective12.50%
(1 of 8 people)
(0 of 7 people)

Most common drug interactions by gender * :

PainAbdominal Pain
Back PainPain

Drug effectiveness by age :

Miralax is effectiven/an/a0.00%
(0 of 1 people)
(0 of 3 people)
(1 of 22 people)
(2 of 2 people)
(0 of 3 people)
(0 of 9 people)
Colace is effectiven/an/a0.00%
(0 of 1 people)
(0 of 3 people)
(1 of 22 people)
(0 of 2 people)
(0 of 3 people)
(0 of 9 people)

Most common drug interactions by age * :

n/aEpistaxisPainDyskinesiaAbdominal PainAnxietyNauseaFall
Decreased AppetiteHeadacheFebrile NeutropeniaNauseaPainConstipationVomiting
Weight DecreasedHaematocrit DecreasedPneumonia FungalDisease ProgressionInjuryVomitingPain
Abdominal PainStaphylococcal InfectionAbdominal PainConstipationNauseaAbdominal PainNausea
LymphadenopathyVomitingChest PainRetinal OedemaAnaemiaDyspnoeaAsthenia
PyrexiaLipase IncreasedMuscle SpasmsVision BlurredPyrexiaAnaemiaConfusional State
Local SwellingNauseaSinusitis FungalVena Cava ThrombosisDyspnoeaPyrexiaDiarrhoea
AtelectasisFallFungal RhinitisDrug IneffectiveCompression FractureAstheniaDehydration
EczemaAbdominal Pain UpperHallucinationHypertensionConstipationGastrooesophageal Reflux DiseaseDyspnoea
Ear PainHaemoglobin DecreasedConfusional StateThrombosisOsteonecrosis Of JawPainHypotension

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Miralax and Colace?

You are not alone! Join a related mobile support group:
- support group for people who take Miralax and Colace
- support group for people who take Colace
- support group for people who take Miralax

Can you answer these questions (Ask a question):

  • Can long-term methadone use cause or increase the risk of colon cancer?
    I had a two-level spinal fusion at L4-S1 in 2000 after being injuried at work in Sept. 24, 1997. I lost everything after...the unjury, ability to do my job, my wife and family (couldn't take the strain) my home, my sense of self and purpose, direction and rating and ability to pay my bills.
    After a long period of waiting to settle my workmens' comp. case, I returned home, from the Bat Area back to Arizona to take of my mother with a yet un dianosed case of moderate dementia.
    Then, in 2011 I had a 2nd surgery to relieve spinal stenosis btwn. L2-L4, just above the fusion site.
    I've been taking methadone since early 2004, a little over ten years, now. I've had high blood pressure since my injury.

    Now, I waiting to be scheduled for a colonoscopy, with my father having had polyps and the way I've been feeling..drained, tired all the time, and stomach pains ( in addition to my chronic low back pain), I...
    find myself wondering if there is any relationtionship between the methadone and other meds and cancer?
  • What is better for motility. miralax or lactolose (1 answer)
    what is easiest on guts had small bowel blockage recently and have diverticulitis
  • Can i take ibuprofen when i'm on the medicine miralax to treat my massive head ache?
    I was recently told by a doctor that I was constipated and that I should take Miralax. I personally don't think I'm constipated. My lower abdomen hurts and so does my head. Every single time I sneeze or cough it hurts really bad! I want to know if I can take some ibuprofen to treat the pain. But I don't want to get even more sick for using it when I'm not suppose to.
  • Can miralax cause hyperactivity?
    8 yr old female takes Miralax for constipation early evening and then gets hyperactive for short period of time. Is this related?
  • Relief from severe stomach pain and alimta?
    Father has just completed second round of maintenance chemo called Alimta. He has already been through aggressive cocktail of Avastin, Carboplatin, and Taclitaxel initially. After that, Avastin as a maintenance chemo every 3 weeks. Radiation was also given specifically to specific spine area. After some time, a PET scan indicated new cancer etc. and it was decided to stop Avastin as it was no longer working. The Alimta was chosen as new maintenance chemo. It has become very obvious that approx day 3....after Alimta, my father expieriences severe abdominal pain. A feeling of heaviness or fullness, associated with rocks grinding sensation. The oncologists always reply with comments about Alimta is usually well tolerated. We increased the protonix......but no real relief! The stomach pain also seems to elevate after my father attempts to eat something. The pain usually last about 4 days, then seems to slowly dissipate. We need help! He has already suffered so much. Hoping for some answers and remedies.

More questions for: Colace, Miralax

You may be interested at these reviews (Write a review):

  • Severe tired taking miralax
  • Hot flashes while taking miralax
    After being on daily dose of Miralax for a year and then going off for a few months, after starting back in 2 weeks, experiencing hot flushes periodically all day long last around 30 seconds. I didn't realize when I first started the Miralax for the 1st year that my Hot Flushes may have been a side affect. I even had requested labs to test for menopause which show negative. Again, after I stopped the miralax the hot flushes ceased. As stated above they are back. These did not wait for me to be on the drug 2 or more years either it was within weeks of starting.
  • Mirroralax causes b.p. spike
    Taking Mirroralax for three weeks. Noticed my B.P. Unusually. High 1 week ago, then last Sat. Right after taking the drug my B.P. Went to 186/101 - I am 65 yrs. old and never had this before. Called my Dr. Got bp medicene -stressed out trying to figure out what was the cause. Then yesterday
    Took another dose and right after my bp again spiked up 186/99. Will never use this again.
  • Hair loss with miralax
    My hair started thinning out probably within a few weeks of starting Miralax on a daily basis. I continued taking it for approximately 6 months never thinking it was the Miralax. It being the only new drug I had been on, I looked on-line and immediately stopped taking it after seeing the side effects of hair loss approximately 3 days ago. So I have no long-term recovery to report as far as return of hair growth. I am keeping my fingers crossed and am already on vitamin supplements...B complex, multi vit, calcium and d. I did start on vit E in hopes that would help.
  • Understanding and living with cancer
    After having one treatment of Gemzar, I had a severe reaction, which caused me to have many seizures. This caused me to developed PRES, which in turn has caused me to have brain damage.When I came out of my induced coma I did not know where I was, nor did I know who my family members were. I could not bathe myself, drive, my speech was broken, I could not add two plus two. I was not the woman I was before Gemzar treatment.Now I am unable to work, I am unable to live on my own, I must always be in the company of another person. I have lost my home and car and job due to this condition. I am currently in speech therapy and soon will start occupational therapy (which is VERY costly) This month marks the one year anniversary of this condition for me. I am making progress. I am able to bathe myself, I can do a little cooking, (although the first time I tried I caught the kitchen on fire a little), I am still living with my Mother , as she is my care taker, my nurse, my driver, my chef, my house cleaner. I currently receive disability. My student loans have gone into default. I could go on but I am depressing myself. I am, followed by my Oncologist every two months now.I want to share this information to anyone and everyone who can benefit from this information.

    Thank you, Chelette Williams, BA,MBA.

More reviews for: Colace, Miralax

Comments from related studies:

  • From this study (1 year ago):

  • Taking benicar for six months no problem. Started taking Miralax about 2 months ago and I have skin rash and itchiness all over my body, even eyelids are itchy.


  • From this study (2 years ago):

  • Patient is 80 years old. Was in Liver Shock and is recovering. In rehab facility within a period of 24 hours, went from using the bathroom to being incontinent of urine and having visual hallucinations. Is still oriented to time and place. Liver values continuing to improve, all labs okay. Sleep deprived. Not eating well.


  • From this study (2 years ago):

  • Vagus Nerve Stimulator (VNS) - Chronic-recurrent, treatment-resistant, depression. Implanted January, 2007.


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Complete drug side effects:

On eHealthMe, Miralax (polyethylene glycol 3350) is often used to treat constipation. Colace (docusate ) is often used to treat constipation. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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