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Review: Mucinex and NyQuil

This review analyzes the effectiveness and drug interactions between Mucinex and NyQuil. It is created by eHealthMe based on reports of 19 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: join a mobile support group for people who take Mucinex and NyQuil >>>

What are the drugs

Mucinex (what 5,822 Mucinex users reported?) has active ingredients of guaifenesin. It is used in cough.

Nyquil (what 1,128 Nyquil users reported?) has active ingredients of acetaminophen; dextromethorphan; doxylamine; pseudoephedrine. It is used in herpes labialis (oral herpes simplex).

On Aug, 12, 2014: 19 people who take Mucinex, NyQuil are studied

Mucinex, NyQuil outcomes

Drug combinations in study:
- Mucinex (guaifenesin)
- NyQuil (acetaminophen; dextromethorphan; doxylamine; pseudoephedrine)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Mucinex is effective0.00%
(0 of 1 people)
(1 of 1 people)
NyQuil is effective0.00%
(0 of 1 people)
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Intentional OverdoseIntentional OverdoseAnxiety
Muscle SpasmsMuscle SpasmsCardiomegaly
Suicide AttemptSuicide AttemptSyncope
Pulmonary Fibrosis
Productive Cough

Drug effectiveness by gender :

Mucinex is effectiven/a50.00%
(1 of 2 people)
NyQuil is effectiven/a0.00%
(0 of 2 people)

Most common drug interactions by gender * :

Subarachnoid HaemorrhagePyrexia
Cerebral InfarctionDyspnoea
Pulmonary HypertensionAnxiety
Cor PulmonaleSarcoidosis
Pulmonary EmbolismProductive Cough
InsomniaObstructive Airways Disorder
DyspnoeaInterstitial Lung Disease
Abdominal Pain UpperLeft Ventricular Dysfunction
PyelonephritisElectrocardiogram T Wave Abnormal

Drug effectiveness by age :

Mucinex is effectiven/an/an/an/an/an/a0.00%
(0 of 1 people)
(1 of 1 people)
NyQuil is effectiven/an/an/an/an/an/a0.00%
(0 of 1 people)
(0 of 1 people)

Most common drug interactions by age * :

n/an/an/aPulmonary HypertensionDepressionEmotional DistressSarcoidosisNasopharyngitis
Cor PulmonaleAnxietyCerebrovascular AccidentObstructive Airways DisorderLower Respiratory Tract Infection
Pulmonary EmbolismHeadacheThalamic InfarctionProductive CoughSwollen Tongue
PyelonephritisIntentional OverdosePyrexiaDysarthria
InsomniaMuscle SpasmsChest X-ray AbnormalWeight Bearing Difficulty
CardiomegalySuicide AttemptWhite Blood Cell Disorder
Abdominal Pain UpperHypertension
PainCerebrovascular Accident
CholecystitisAbdominal Pain

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group to help out with your experience or learn from others anytime and anywhere:
- group for people who take Mucinex and NyQuil
- group for people who take Mucinex
- group for people who take NyQuil

Comments from related studies:

  • From this study (2 years ago):

  • after taking these drugs I found relief for nasal congestion but developed queezing with chest congestion


Can you answer these questions (what is this?):

More questions for: Mucinex, NyQuil

More reviews for: Mucinex, NyQuil

Complete drug side effects:

On eHealthMe, Mucinex (guaifenesin) is often used to treat cough. Nyquil (acetaminophen; dextromethorphan; doxylamine; pseudoephedrine) is often used to treat herpes labialis (oral herpes simplex). Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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