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Review: Nucynta and Lorazepam

This review analyzes the effectiveness and drug interactions between Nucynta and Lorazepam. It is created by eHealthMe based on reports of 54 people who take the same drugs from FDA and social media, and is updated regularly.

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What are the drugs

Nucynta (what 1,689 Nucynta users reported?) has active ingredients of tapentadol hydrochloride. It is used in pain.

Lorazepam (what 47,063 Lorazepam users reported?) has active ingredients of lorazepam. It is used in stress and anxiety.

On Aug, 21, 2014: 54 people who take Nucynta, Lorazepam are studied

Nucynta, Lorazepam outcomes

Drug combinations in study:
- Nucynta (tapentadol hydrochloride)
- Lorazepam (lorazepam)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Nucynta is effectiven/a50.00%
(1 of 2 people)
n/an/an/an/an/an/a
Lorazepam is effective0.00%
(0 of 1 people)
n/a0.00%
(0 of 1 people)
n/an/an/an/a0.00%
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DysphagiaAbdominal PainVomitingn/an/an/an/aAbdominal Pain
HospitalisationInflammatory Bowel DiseaseDizziness
Withdrawal SyndromeDizzinessConstipation
DeathConstipationInflammatory Bowel Disease
Musculoskeletal PainApathyAnxiety
HypersensitivityDyspepsiaSuicidal Ideation
Oedema PeripheralCompleted SuicideHypoglycaemia
UrticariaVomitingDyspnoea
SepsisConfusional State
ErythemaOedema Peripheral

Drug effectiveness by gender :

FemaleMale
Nucynta is effectiven/a50.00%
(1 of 2 people)
Lorazepam is effective0.00%
(0 of 1 people)
0.00%
(0 of 2 people)

Most common drug interactions by gender * :

FemaleMale
Abdominal PainAnxiety
DizzinessHypoglycaemia
Inflammatory Bowel DiseaseSuicidal Ideation
ConstipationDepression
Confusional StateCerebrovascular Accident
DisorientationSuicide Attempt
Weight IncreasedAmnestic Disorder
ApathyThroat Tightness
DyspepsiaErythema
Dry MouthOedema Peripheral

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Nucynta is effectiven/an/an/an/an/a100.00%
(1 of 1 people)
n/a0.00%
(0 of 1 people)
Lorazepam is effectiven/an/an/an/a0.00%
(0 of 1 people)
0.00%
(0 of 1 people)
n/a0.00%
(0 of 1 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/an/aPlatelet Count DecreasedHospitalisationSomnambulismAnxietyAbdominal Pain
Withdrawal SyndromeDystoniaHypoglycaemiaConstipation
Weight IncreasedSuicidal IdeationDizziness
Suicide AttemptCerebrovascular AccidentInflammatory Bowel Disease
DepressionDizzinessDyspnoea
Amnestic DisorderDry MouthUrticaria
Poor Quality SleepConfusional StateDysphagia
Binge EatingOedema PeripheralApathy
Pain In ExtremityPneumoniaDysphonia
Back PainDiarrhoeaAnaphylactic Shock

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Nucynta and Lorazepam?

Get connected! Join a mobile support group:
- group for people who take Nucynta and Lorazepam
- group for people who take Lorazepam
- group for people who take Nucynta

Comments from related studies:

  • From this study (2 years ago):

  • sonya on Jun, 22, 2012:

    my mom, 75, with copd has been homebound on purpose for the past 5 years - she is taking hydrocodone, trazodone, ativan, clonazepam - she's been falling, has gotten shorter, doesn't hold her head up - from what i can tell this is a horrible combination of meds and one doctor is giving her all this - can you tell me the symptoms and side effects of this combination please??? asap!!! thank you, sonya

    Reply

    JT on Jul, 2, 2012:

    Hi Sonya.

    This combinations of meds is much too sedating and could cause respiratory depression.Also, why would your Mom be on 2 benzodiazepines i.e. clonazepan and ativan.Ativan can sometimes be used to help with sleeping but it seems your Mom is taking Trazodone for that.The Hydrocodone is a pain killer but can sedate also.Further, it is addictive but if she needs ? Why not Advil.Like you, I would also be concerned with falling at her age
    i.e. broken hip etc.which could lead to her being bed ridden if she manges to get through the operation.You need another Dr.This combination is seldom prescribed for someone her age.Warmest, JT

    Reply

    Leena on Oct, 20, 2012:

    Sonya,
    I used to take klonopin, ativan, and hydrocodone. The ativan was only for emergencies (i.e. extreme panic attacks). I found that mixing klonopin and hydrocodone drastically changed my personality to the point where they suspected I had a severe mood or personality disorder. When I stopped this combo my personality returned to normal. I have seen the same thing happen in 100% of cases where these drugs are mixed (n=3). The symptoms it produces can resemble borderline personality disorder &/or bipolar. Basically mood swings that are disproportionate to the situation. Common sense seems to disappear. People also seemed to think I was being disingenuous but in reality I was too confused to remain consistent. I have never taken trazadone but my sister took it mixed with klonopin and it would knock her out for a long time, sometimes an entire day. Hope that helps a little. All the best to you and your mother.

    Reply

    Ms67GTO on Nov, 21, 2012:

    Leena, I have taken Klonopin (Clonazepam) in combination with hydrocodone for a number of years with absolutely no side effects. Both are extremely beneficial to my conditions. I'm truly sorry you suffered nasty effects from this combo. Each person's metabolism and chemical make-up are very different. What may work for some, doesn't work for others. After hearing someone's success story using particular drugs, others want to copy their regimen in hopes of the same relief. It may have worked for them, but you may suffer dire consequences.

    Reply

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Complete drug side effects:

On eHealthMe, Nucynta (tapentadol hydrochloride) is often used to treat pain. Lorazepam (lorazepam) is often used to treat stress and anxiety. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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