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Review: taking Phenytoin and Vimpat together

Summary: drug interactions are reported among people who take Phenytoin and Vimpat together.

This review analyzes the effectiveness and drug interactions between Phenytoin and Vimpat. It is created by eHealthMe based on reports of 275 people who take the same drugs from FDA and social media, and is updated regularly.





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What are the drugs

Phenytoin has active ingredients of phenytoin. It is often used in epilepsy. (latest outcomes from 11,104 Phenytoin users)

Vimpat has active ingredients of lacosamide. It is often used in epilepsy. (latest outcomes from 2,069 Vimpat users)

On Feb, 27, 2015: 275 people who take Phenytoin, Vimpat are studied

Phenytoin, Vimpat outcomes

Drug combinations in study:
- Phenytoin (phenytoin)
- Vimpat (lacosamide)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Phenytoin is effectiven/an/an/an/a0.00%
(0 of 1 people)
Vimpat is effectiven/an/an/a0.00%
(0 of 1 people)

Drug effectiveness by gender :

Phenytoin is effective0.00%
(0 of 1 people)
Vimpat is effective0.00%
(0 of 1 people)

Drug effectiveness by age :

Phenytoin is effectiven/an/an/an/a0.00%
(0 of 1 people)
Vimpat is effectiven/an/an/an/a0.00%
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Vision BlurredConvulsionIschaemiaUrticariaBruxismn/aToxic EncephalopathyConvulsion
DiplopiaStatus EpilepticusHyperhidrosisCatatoniaStatus EpilepticusDiplopia
ConvulsionEncephalopathyTransaminases IncreasedPost-traumatic EpilepsyBalance Disorder
PyrexiaSudden DeathChest DiscomfortHypertensionNeurotoxicity
Drug Level FluctuatingAtaxiaDrug Screen PositiveDizziness
LeukopeniaLoss Of ConsciousnessCardiac HypertrophyDrug Ineffective
DizzinessTremorAtrial FlutterStatus Epilepticus
Jugular Vein ThrombosisCardiomegalySudden DeathGait Disturbance
Tracheal StenosisBacterial Test PositiveAtrial FibrillationGrand Mal Convulsion
Selective AbortionUrinary Sediment PresentAtrioventricular Block First DegreeAnticonvulsant Drug Level Decreased

Most common drug interactions by gender * :

Balance DisorderAnger
DiplopiaVision Blurred
Anticonvulsant Drug Level DecreasedPruritus
Gait DisturbanceSomnolence
Drug IneffectiveDrug Ineffective
Status EpilepticusDepression
Grand Mal ConvulsionAnorexia Nervosa

Most common drug interactions by age * :

Drug IneffectiveDroolingConvulsionHeadacheDiplopiaVision BlurredConvulsionConvulsion
PyrexiaPneumoniaDizzinessBalance DisorderDiplopiaStatus EpilepticusAngioedema
IrritabilityFacial Bones FractureFatigueConvulsionConvulsionTremorDisturbance In Attention
AngerCerebral AtrophySleep DisorderNeurotoxicityDrug Level FluctuatingDisorientationDeath
Depressed MoodGrand Mal ConvulsionConvulsionDrug IneffectiveTremorEncephalopathyLeukopenia
Oral HerpesVomitingPregnancyAnticonvulsant Drug Level DecreasedRashBalance DisorderFall
Head BangingVisual ImpairmentSelective AbortionDizzinessCoordination AbnormalGait DisturbancePyrexia
HypophagiaDrug IneffectiveDrug AbuseAtaxiaLethargyComplex Partial SeizuresPruritus
Oral DiscomfortCondition AggravatedAmmonia IncreasedStatus EpilepticusDizzinessCardiomegalyHead Injury
Tonic ConvulsionDyspnoeaLoss Of ConsciousnessGait DisturbanceBlood Pressure IncreasedCerebellar AtrophyDementia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Phenytoin and Vimpat?

You are not alone! Join a related mobile support group:
- support group for people who take Phenytoin and Vimpat
- support group for people who take Phenytoin
- support group for people who take Vimpat

Can you answer these questions (Ask a question):

  • Lichenoid dermatitis caused by vimpat
    I was on tegretol and found out it was causing my lichenoid dermatitis so now I'm on vimpat and was wondering if Vimpat causes lichenoid dermatitis too.
  • Can this medication be causeing me low blood sugar which causes my seizures to come more often?
    I begin taking Vimpat and since then have become shaky and nauseated at times. More then once had a seizure after feeling this way. I begin to check blood glucose from my sister machine and noticed my blood sugar has dropped when feeling this way. I want to know if Vimpat is causing this and what can I do about it. I'm already epileptic. Thank you.
  • Does indigestion cause seizure?
    in 22 years of seizure a good amount of water and sleep will help. Relax the eyes is important. Tegretol xr is the best drug for me. The only negative is I have to increase the amount taken every few years. I am on 1600mg a day now....Please share with me what you know.
  • Does dilatin and topomax cause bad breath and b.o
    I take very good care of hygeine but still notice bad breath and excessive sweating with bad smell
  • I am taking a mix of trileptal. vimpat and keppra and suffering from suffer mood and agreesive episodes is that common
    I have been going through a change of my epilepsy medication, I take 100mg twice pd of vimpat, 450 twice pd trileptal and 1500mg twice pd of keppra. I have been suffering massive mood swings, serious aggression and un-well thoughts. my doctor has suggested surgery to remove my hippocampus. today I a fit of rage over took me which almost caused harm to myself and another. this is not the type of person I am or have ever been. there is no history of mental illness in my family, its been suggested I have the symptoms of bi-polar. I don't know if its ME who is nuts or behaviour this way its due to my medication, any thoughts opinions personal experiences ect ect would be helpful as I am at my wits end cheers

More questions for: Phenytoin, Vimpat

You may be interested at these reviews (Write a review):

  • Pros and cons of vimpat for me
    I take a huge list of drugs unfortunately I have RA, Partial Small intestinal block, diabetes, asthma, allergies. Immune problems. Vimpat has done wonders for the migraines and seizure problems but the side effects are almost as bad. I have visual disturbances but I also have auras so who knows. The worst problems are shaking, memory, (worst is words) and sudden jerks and nerve firings which produce jerks or just loss of muscle control. Some of the random nerve firings can disrupt my whole body but they only last a fraction of a second and are more annoying than anything else. I tried at least one seizure agent from every category of meds nothing worked except Vimpat. I tried the whole range of dosing. Less than 300mg did not work and I only have the side effects above 250mg so apparently for me it has to cause side effects to work. Compared to the time losses, horrible headaches that are nearly continuous for for me they are worth it, I think. Now I am wondering now that I know where those effects are coming from.
  • Dilantin causes false positive testing
    False positive hampering use of cocaine..private test has benzoylecgonine. My doctor and pharmacist have both said Dilantin has caused false positive. DCF want "expert" statements..where do I find an expert?

More reviews for: Phenytoin, Vimpat

Comments from related studies:

  • From this study (1 year ago):

  • he has cerebro pausy can, t talk


  • From this study (3 years ago):

  • Dan on Feb, 5, 2012:

    I have not long ago been put on Lacosamide 200mg twice daily.Along with Keppra 1500mg,Phenytoin 425 Daily,Clonazepam 2mg x 3 daily and Sertraline 150mg

    Since trying to reduce Lacosamide I've had nightmares and feel really tired all the time.Has anyone else experienced this.


Complete drug side effects:

On eHealthMe, Phenytoin (phenytoin) is often used to treat epilepsy. Vimpat (lacosamide) is often used to treat epilepsy. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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