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Review: Phenytoin and Vimpat

This review analyzes the effectiveness and drug interactions between Phenytoin and Vimpat. It is created by eHealthMe based on 271 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Mar, 31, 2014: 271 people who reported to have interactions when taking Phenytoin, Vimpat are studied

Trend of Phenytoin, Vimpat's drug interactions, side effects and effectiveness reports (3164999)

Drug combinations in study:
- Phenytoin (phenytoin)
- Vimpat (lacosamide)

eHealthMe real world results:

Most common interactions experienced by people in the use of Phenytoin, Vimpat:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)271
Diplopia (double vision)194
Balance Disorder184
Drug Interaction146
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)132
Pyrexia (fever)72
Anticonvulsant Drug Level Decreased60
Drug Ineffective58
Gait Disturbance48

Most common interactions experienced by people in long term use of Phenytoin, Vimpat:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Catatonia (unresponsive to external stimuli)6
Bruxism (habitual grinding of the teeth, typically during sleep)6
Toxic Encephalopathy (a degenerative neurologic disorder caused by exposure to toxic substances)6
Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)6
Hypertension (high blood pressure)6
Sudden Death6
Post-traumatic Epilepsy4
Drug Screen Positive4
Cardiac Hypertrophy (thickening of the heart muscle)4
Urticaria (rash of round, red welts on the skin that itch intensely)2

How effective are the drugs:


Top conditions involved for these people * :

  1. Epilepsy
  2. Convulsion
  3. Status epilepticus
  4. Complex partial seizures
  5. Grand mal convulsion

Top co-used drugs for these people * :

  1. Dilantin
  2. Keppra
  3. Levetiracetam
  4. Topiramate
  5. Oxcarbazepine

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Phenytoin, Vimpat

You can also:

Complete drug side effects:

On eHealthMe, Phenytoin (phenytoin) is often used to treat epilepsy. Vimpat (lacosamide) is often used to treat epilepsy. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (6 months ago):

  • he has cerebro pausy can, t talk


  • From this study (2 years ago):

  • Dan on Feb, 5, 2012:

    I have not long ago been put on Lacosamide 200mg twice daily.Along with Keppra 1500mg,Phenytoin 425 Daily,Clonazepam 2mg x 3 daily and Sertraline 150mg

    Since trying to reduce Lacosamide I've had nightmares and feel really tired all the time.Has anyone else experienced this.


Can you answer these questions (what is this?):

More questions for: Phenytoin, Vimpat

More reviews for: Phenytoin, Vimpat

Recent related drug studies:

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Related studies

- Phenytoin side effects
- Vimpat side effects



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