Drug interactions between Plaquenil and Ibuprofen
This is a real world study of Plaquenil and Ibuprofen drug interactions. The study is created by eHealthMe based on 670 reports from FDA.
Do you have chronic disease and take multiple drugs? eHealthMe can monitor your drugs and notify you when there are serious drug reactions detected. Our original studies have been used on premier medical publications. The monitor will be personalized to your gender and age. Start now
What are the drugs
Plaquenil has active ingredients of hydroxychloroquine sulfate. It is used in systemic lupus erythematosus, rheumatoid arthritis, sjogren syndrome, arthritis, mixed connective tissue disease, autoimmune disorder.
Ibuprofen has active ingredients of ibuprofen. It is used in pain, headache, back pain - low, inflammation, arthritis, fever.
On May, 4, 2013: 670 people who reported to have interactions when taking Ibuprofen, Plaquenil are studied

Drug combinations in study:
- Ibuprofen (ibuprofen)
- Plaquenil (hydroxychloroquine sulfate)
Most common interactions experienced by people in the use of Ibuprofen, Plaquenil:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports | |
| 1 | Dyspnoea | 98 |
| 2 | Diarrhoea | 94 |
| 3 | Arthralgia | 86 |
| 4 | Pyrexia | 68 |
| 5 | Nausea | 65 |
| 6 | Headache | 61 |
| 7 | Pain | 53 |
| 8 | Fatigue | 52 |
| 9 | Fall | 38 |
| 10 | Insomnia | 38 |
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Most common interactions experienced by people in long term use of Ibuprofen, Plaquenil:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports | |
| 1 | Eustachian Tube Dysfunction | 22 |
| 2 | Rhinitis Allergic | 22 |
| 3 | Dyspnoea | 14 |
| 4 | Bronchitis | 11 |
| 5 | Pharyngitis | 11 |
| 6 | Tracheitis | 11 |
| 7 | Pathological Gambling | 11 |
| 8 | Psychiatric Symptom | 11 |
| 9 | Otitis Media Acute | 11 |
| 10 | Chest Pain | 7 |
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Top conditions involved for these people * :
- Rheumatoid arthritis
- Systemic lupus erythematosus
- Pain
- Asthma
- Prophylaxis
Top co-used drugs for these people * :
- Methotrexate
- Prednisone
- Folic acid
- Enbrel
- Humira
* Approximation only. Some reports may have incomplete information.
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Side effects in real world:
On eHealthMe, Plaquenil (hydroxychloroquine sulfate) is often used to treat systemic lupus erythematosus. Ibuprofen (ibuprofen) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.
What is the drug used for and how effective is it:
Other drugs that are used to treat the same conditions:
Comments from related studies:
From this study (2 months ago):
From this study (3 months ago):
From this study (4 months ago):
From this study (3 years ago):
eosinophilia bowel problems with pain lethargic
I found out I have svt heart conditions and was wondering if any of these drugs have an effect or cause any problems with it or cause you to get svt?
Mirena put in January 2012 and removed July 2012. Started getting sick June 2012 and diagnosed with Kidney Stones, bone spurs, and Lupus since.
Fatal - severe asymptomatic broncho-pneumonia within four hours.
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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
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