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Review: taking Prednisone and Methotrexate together

Summary: drug interactions are reported among people who take Prednisone and Methotrexate together.

This review analyzes the effectiveness and drug interactions between Prednisone and Methotrexate. It is created by eHealthMe based on reports of 25,951 people who take the same drugs from FDA and social media, and is updated regularly.

 

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On Mar, 28, 2015: 25,951 people who take Prednisone, Methotrexate are studied

Prednisone, Methotrexate outcomes

Drug combinations in study:
- Prednisone (prednisone)
- Methotrexate (methotrexate sodium)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Prednisone is effective27.59%
(8 of 29 people)
33.33%
(20 of 60 people)
33.33%
(11 of 33 people)
51.22%
(21 of 41 people)
47.37%
(18 of 38 people)
55.00%
(22 of 40 people)
62.50%
(15 of 24 people)
100.00%
(1 of 1 people)
Methotrexate is effective4.35%
(1 of 23 people)
19.72%
(14 of 71 people)
17.86%
(5 of 28 people)
38.46%
(15 of 39 people)
26.19%
(11 of 42 people)
40.00%
(12 of 30 people)
45.00%
(9 of 20 people)
0.00%
(0 of 2 people)

Drug effectiveness by gender :

FemaleMale
Prednisone is effective43.96%
(91 of 207 people)
42.37%
(25 of 59 people)
Methotrexate is effective23.27%
(47 of 202 people)
37.74%
(20 of 53 people)

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Prednisone is effectiven/a100.00%
(2 of 2 people)
20.00%
(2 of 10 people)
25.00%
(3 of 12 people)
20.90%
(14 of 67 people)
23.47%
(23 of 98 people)
27.40%
(40 of 146 people)
33.33%
(32 of 96 people)
Methotrexate is effectiven/a100.00%
(2 of 2 people)
11.11%
(1 of 9 people)
15.38%
(2 of 13 people)
7.35%
(5 of 68 people)
8.33%
(8 of 96 people)
24.32%
(27 of 111 people)
23.91%
(22 of 92 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
PyrexiaPyrexiaPneumoniaPneumoniaDiarrhoeaPyrexiaOedema PeripheralPyrexia
Febrile NeutropeniaPneumoniaPneumonitisPyrexiaFatigueWeight DecreasedAstheniaArthralgia
PneumoniaAnaemiaNauseaNauseaPneumoniaDeathPyrexiaDrug Ineffective
NauseaCellulitisCellulitisArthralgiaSepsisFatigueCoughNausea
HypotensionNauseaDrug IneffectiveRespiratory FailureNauseaAnaemiaHeadacheRheumatoid Arthritis
VomitingCardio-respiratory ArrestUrinary Tract InfectionRheumatoid ArthritisWeight DecreasedPancytopeniaChest PainPain
DiarrhoeaRenal Failure AcuteAnaemiaRenal FailureRheumatoid ArthritisPneumoniaLung DisorderPneumonia
DyspnoeaWeight DecreasedWeight DecreasedFatigueImpaired HealingNauseaCerebrovascular AccidentFatigue
HeadacheFebrile NeutropeniaPulmonary FibrosisVomitingDepressionMalaiseChillsDyspnoea
HypertensionPainDyspnoeaSepsisInsomniaGastric DisorderArthralgiaAsthenia

Most common drug interactions by gender * :

FemaleMale
ArthralgiaPyrexia
PyrexiaPneumonia
NauseaDrug Ineffective
Drug IneffectiveArthralgia
PainRheumatoid Arthritis
Rheumatoid ArthritisNausea
FatigueAsthenia
PneumoniaPain
DyspnoeaFatigue
HeadacheDyspnoea

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
NeutropeniaPyrexiaCrohn's DiseasePyrexiaPyrexiaPyrexiaArthralgiaPneumonia
Gamma-glutamyltransferase IncreasedDrug ToxicityPyrexiaArthralgiaNauseaArthralgiaPyrexiaPyrexia
Respiratory Syncytial Virus InfectionPneumoniaHypotensionNauseaArthralgiaDrug IneffectiveNauseaArthralgia
DiarrhoeaFebrile NeutropeniaNeutropeniaHeadacheDrug IneffectiveNauseaPainDrug Ineffective
StomatitisConvulsionAbdominal PainDyspnoeaVomitingRheumatoid ArthritisDrug IneffectiveNausea
PyrexiaMucosal InflammationVomitingDrug IneffectiveInjection Site Reaction NosPainFatigueAsthenia
ThrombocytopeniaNeutropeniaHyperglycaemiaPainHeadacheHeadacheOedema PeripheralRheumatoid Arthritis
Pain In ExtremityVomitingHyperbilirubinaemiaChest PainRheumatoid ArthritisFatigueRheumatoid ArthritisFatigue
Normochromic Normocytic AnaemiaAlanine Aminotransferase IncreasedHeadacheRheumatoid ArthritisInjection Site HaemorrhageOedema PeripheralDiarrhoeaDyspnoea
Molluscum ContagiosumAbdominal PainNauseaWeight DecreasedDiarrhoeaInjection Site Reaction NosHeadacheFall

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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- support group for people who take Methotrexate
- support group for people who take Prednisone

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Prednisone (prednisone) is often used to treat asthma. Methotrexate (methotrexate sodium) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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