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Review: Prednisone and Methotrexate

This review analyzes the effectiveness and drug interactions between Prednisone and Methotrexate. It is created by eHealthMe based on reports of 25,932 people who take the same drugs from FDA and social media, and is updated regularly.

Get connected: join a mobile support group for people who take Prednisone and Methotrexate >>>

What are the drugs

Prednisone (latest outcomes from 149,968 users) has active ingredients of prednisone. It is often used in rheumatoid arthritis.

Methotrexate (latest outcomes from 131,165 users) has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis.

On Oct, 26, 2014: 25,932 people who take Prednisone, Methotrexate are studied

Prednisone, Methotrexate outcomes

Drug combinations in study:
- Prednisone (prednisone)
- Methotrexate (methotrexate sodium)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Prednisone is effective27.59%
(8 of 29 people)
35.09%
(20 of 57 people)
32.26%
(10 of 31 people)
50.00%
(20 of 40 people)
51.52%
(17 of 33 people)
56.76%
(21 of 37 people)
62.50%
(15 of 24 people)
100.00%
(1 of 1 people)
Methotrexate is effective4.55%
(1 of 22 people)
19.40%
(13 of 67 people)
19.23%
(5 of 26 people)
36.84%
(14 of 38 people)
27.03%
(10 of 37 people)
39.29%
(11 of 28 people)
45.00%
(9 of 20 people)
0.00%
(0 of 2 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
PyrexiaPyrexiaPneumoniaPneumoniaDiarrhoeaPyrexiaOedema PeripheralPyrexia
Febrile NeutropeniaPneumoniaPneumonitisPyrexiaPneumoniaWeight DecreasedAstheniaArthralgia
PneumoniaAnaemiaNauseaNauseaFatigueDeathPyrexiaDrug Ineffective
NauseaCellulitisCellulitisRespiratory FailureSepsisFatigueCoughNausea
HypotensionNauseaDrug IneffectiveArthralgiaNauseaAnaemiaHeadacheRheumatoid Arthritis
VomitingCardio-respiratory ArrestAnaemiaRheumatoid ArthritisWeight DecreasedPneumoniaChest PainPain
DiarrhoeaRenal Failure AcuteUrinary Tract InfectionFatigueRheumatoid ArthritisPancytopeniaLung DisorderPneumonia
DyspnoeaWeight DecreasedVomitingRenal FailureImpaired HealingNauseaCerebrovascular AccidentFatigue
HeadacheFebrile NeutropeniaDyspnoeaVomitingInsomniaPleural EffusionChillsDyspnoea
HypertensionPainWeight DecreasedSepsisChest PainMalaiseArthralgiaAsthenia

Drug effectiveness by gender :

FemaleMale
Prednisone is effective45.13%
(88 of 195 people)
42.11%
(24 of 57 people)
Methotrexate is effective23.28%
(44 of 189 people)
37.25%
(19 of 51 people)

Most common drug interactions by gender * :

FemaleMale
ArthralgiaPyrexia
PyrexiaPneumonia
NauseaDrug Ineffective
Drug IneffectiveArthralgia
PainRheumatoid Arthritis
Rheumatoid ArthritisNausea
FatigueAsthenia
PneumoniaPain
DyspnoeaFatigue
HeadacheDyspnoea

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Prednisone is effectiven/a100.00%
(2 of 2 people)
20.00%
(2 of 10 people)
25.00%
(3 of 12 people)
21.88%
(14 of 64 people)
26.19%
(22 of 84 people)
27.46%
(39 of 142 people)
35.29%
(30 of 85 people)
Methotrexate is effectiven/a100.00%
(2 of 2 people)
11.11%
(1 of 9 people)
8.33%
(1 of 12 people)
7.94%
(5 of 63 people)
9.76%
(8 of 82 people)
24.30%
(26 of 107 people)
24.69%
(20 of 81 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
NeutropeniaPyrexiaCrohn's DiseasePyrexiaPyrexiaPyrexiaArthralgiaPneumonia
Gamma-glutamyltransferase IncreasedDrug ToxicityPyrexiaArthralgiaNauseaArthralgiaPyrexiaPyrexia
Respiratory Syncytial Virus InfectionPneumoniaHypotensionNauseaArthralgiaDrug IneffectiveNauseaArthralgia
DiarrhoeaFebrile NeutropeniaNeutropeniaHeadacheDrug IneffectiveNauseaPainDrug Ineffective
StomatitisConvulsionAbdominal PainDrug IneffectiveVomitingRheumatoid ArthritisDrug IneffectiveNausea
PyrexiaMucosal InflammationVomitingDyspnoeaInjection Site Reaction NosPainFatigueAsthenia
ThrombocytopeniaNeutropeniaHyperglycaemiaPainHeadacheHeadacheOedema PeripheralRheumatoid Arthritis
Pain In ExtremityVomitingHyperbilirubinaemiaChest PainRheumatoid ArthritisFatigueRheumatoid ArthritisFatigue
Normochromic Normocytic AnaemiaAlanine Aminotransferase IncreasedHeadacheRheumatoid ArthritisInjection Site HaemorrhageOedema PeripheralDiarrhoeaDyspnoea
Molluscum ContagiosumAbdominal PainNauseaWeight DecreasedDiarrhoeaInjection Site Reaction NosHeadacheFall

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Prednisone and Methotrexate?

Get connected! Join a related mobile support group:
- support group for people who take Prednisone and Methotrexate
- support group for people who take Methotrexate
- support group for people who take Prednisone

Comments from related studies:

  • From this study (2 weeks ago):

  • I find I can read something but have a difficult time relating what I have just read to another person. Although I understand what I have read, I just seem to have great difficulty putting it into words to relate

    Reply

  • From this study (3 weeks ago):

  • Going blind and nothing seems to be helping

    Reply

    kss40 on Oct, 4, 2014:

    What do u mean going blind? Do u have RP and CME that is why u r on Diamox? U neec someone to talk to?

    Reply

  • From this study (4 weeks ago):

  • The list above is what I take daily to ease my joint pain due to Rheumatoid Arthritis, not sure if any one of these contradicts the effect of my medications, however I am always looking for relieve.

    Reply

Post a new comment    OR    Read more comments

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More reviews for: Methotrexate, Prednisone

Complete drug side effects:

On eHealthMe, Prednisone (prednisone) is often used to treat rheumatoid arthritis. Methotrexate (methotrexate sodium) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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